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https://www.readbyqxmd.com/read/28727318/appropriate-cyclic-tensile-strain-promotes-biological-changes-of-cranial-base-synchondrosis-chondrocytes
#1
F Chu, Q Feng, Z Hu, G Shen
OBJECTIVES: This study was designed to clarify biological changes of cranial base synchondrosis chondrocytes (CBSCs) upon cyclic tensile strain (CTS) loading which simulated orthopaedic mechanical protraction on cranial base synchondroses (CBS). MATERIAL AND METHODS: A two-step digestion method was used to isolate CBSCs obtained from 1-week-old Sprague Dawley rats. Immunohistochemical staining of type II collagen and Sox9 was conducted to identify chondrocytes. A CTS of 1 Hz and 10% elongation was applied to the second passage of CBSCs by FX-5000™ Tension System for 24 hours...
August 2017: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/28726223/comprehensive-study-on-parameter-sensitivity-for-flow-and-nutrient-modeling-in-the-hydrological-simulation-program-fortran-model
#2
Chuan Luo, Zhaofu Li, Min Wu, Kaixia Jiang, Xiaomin Chen, Hengpeng Li
Numerous parameters are used to construct the HSPF (Hydrological Simulation Program Fortran) model, which results in significant difficulty in calibrating the model. Parameter sensitivity analysis is an efficient method to identify important model parameters. Through this method, a model's calibration process can be simplified on the basis of understanding the model's structure. This study investigated the sensitivity of the flow and nutrient parameters of HSPF using the DSA (differential sensitivity analysis) method in the Xitiaoxi watershed, China...
July 19, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28712882/perfusion-of-muscle-flaps-independent-of-the-anatomical-vascular-pedicle-pedicle-autonomy
#3
K Bradshaw, M Wagels
INTRODUCTION: Free muscle flaps are being used more commonly for complex lower limb reconstruction. Up to 33% of flaps used to reconstruct lower limb trauma will require an orthopaedic procedure after reconstruction. To date there have been only case reports detailing the variable survival of muscle flaps after actual or simulated pedicle injury and the process and timeframe of neovascularisation remains undefined. We aim to show that perfusion of a muscle flap is possible after injury to its anatomical vascular pedicle...
June 7, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28712686/using-touch-surgery-to-improve-surgical-education-in-low-and-middle-income-settings-a-randomized-control-trial
#4
Gisele Juru Bunogerane, Kathryn Taylor, Yihan Lin, Ainhoa Costas-Chavarri
BACKGROUND/OBJECTIVE: There is a severe surgical workforce shortage in Rwanda. Innovative educational tools must be introduced to train more residents and increase surgical capacity. Touch Surgery (TS) is a smartphone application that offers trainees the opportunity to practice operations; however, its effect is unknown in low- and middle-income countries. Our objectives were to determine the training effect of TS and its feasibility for use in surgery education in a low-resource setting...
July 13, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28705649/a-new-approach-for-endoscopicneurolysis-of-the-supra-scapular-nerve-at-the-spinoglenoidnotch-a-preliminary-cadaver-study
#5
Marc-Alexandre Loirat, Maxime Tierny, Anthony Hervé, Arthur Lignel, Eric Berton, Mickaël Ropars, Hervé Thomazeau
INTRODUCTION: The suprascapular nerve (SSN) can become compressedatits 2 scapularattachments: the suprascapular and the spinoglenoid notch. The objective of this study was to describe a new arthroscopicapproach for SSN neurolysis at the spinoglenoid notch. METHOD: 10 cadaver shoulderswereused. Two weredissected to simulate the "classical" arthroscopic approach and to help in the creation of a new "direct medial retrospinal" approach. Eight othershoulders were used to validatethis new approach, with control of the whole juxta-glenoidcourse of the SSN as criterion of success...
July 10, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28698836/copper-as-an-alternative-antimicrobial-coating-for-implants-an-in-vitro-study
#6
Claudia Bergemann, Sarah Zaatreh, Katharina Wegner, Kathleen Arndt, Andreas Podbielski, Rainer Bader, Cornelia Prinz, Ulrich Lembke, J Barbara Nebe
AIM: To investigate osteoconductive and antimicrobial properties of a titanium-copper-nitride (TiCuN) film and an additional BONIT(®) coating on titanium substrates. METHODS: For micro-structuring, the surface of titanium test samples was modified by titanium plasma spray (TPS). On the TPS-coated samples, the TiCuN layer was deposited by physical vapor deposition. The BONIT(®) layer was coated electrochemically. The concentration of copper ions released from TiCuN films was measured by atomic absorption spectrometry...
June 24, 2017: World Journal of Transplantation
https://www.readbyqxmd.com/read/28698016/the-timing-and-importance-of-motor-skills-course-in-knee-arthroscopy-training
#7
Engin Çetinkaya, Hakan Çift, Ahmet Aybar, Ersin Erçin, Gamze Babür Güler, Oğuz Poyanlı
OBJECTIVES: The aim of this prospective study is to evaluate the impact of the simulation training program in learning duration of arthroscopic motor skills. Furthermore, we investigated the difference between junior and experienced residents in the improvement of arthroscopic motor skills duration. METHODS: We established 2 study groups according to participants' year of experience in orthopedic residency with junior group residents with three years or less than three years experience as group 1 and experienced group with over 3 years of experience as group 2...
July 8, 2017: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/28680331/immunotoxicity-evaluation-of-novel-bioactive-composites-in-male-mice-as-promising-orthopaedic-implants
#8
Gehan T El-Bassyouni, Mariam G Eshak, Ibrahim A H Barakat, Wagdy K B Khalil
OBJECTIVE: In orthopaedics, novel bioactive composites are largely needed to improve the synthetic achievement of the implants. In this work, semiconducting metal oxides such as SiO2, TiO2, and ZrO2 particles (Ps) were used individually and in different ratios to obtain different biphasic composites. The immunotoxicity of these composites was tested to inspect the potential toxicity prior to their use in further medical applications. MATERIALS AND METHODS: In vitro mineralisation ability was inspected by soaking the composites in simulated body fluid (SBF)...
2017: Central-European Journal of Immunology
https://www.readbyqxmd.com/read/28675248/quick-bacteriophage-mediated-bioluminescence-assay-for-detecting-staphylococcus-spp-in-sonicate-fluid-of-orthopaedic-artificial-joints
#9
Katja Šuster, Aleš Podgornik, Andrej Cör
Staphylococcus spp. accounts for up to two thirds of all microorganisms causing prosthetic joint infections, with Staphylococcus aureus and Staphylococcus epidermidis being the major cause. The present study describes a diagnostic model to detect staphylococci using a specific bacteriophage and bioluminescence detection, exploring the possibility of its use on sonicate fluid of orthopaedic artificial joints. Intracellular adenosine-5'-triphosphate release by bacteriophage mediated lysis of staphylococci was assessed to determine optimal parameters for detection...
July 4, 2017: New Microbiologica
https://www.readbyqxmd.com/read/28651976/observational-learning-during-simulation-based-training-in-arthroscopy-is-it-useful-to-novices
#10
Marie-Eve LeBel, John Haverstock, Sayra Cristancho, Lucia van Eimeren, Gavin Buckingham
OBJECTIVE: Observing experts constitutes an important and common learning experience for surgical residents before operating under direct guidance. However, studies suggest that exclusively observing experts may induce suboptimal motor learning, and watching errors from non-experts performing simple motor tasks may generate better performance. We investigated whether observational learning is transferrable to arthroscopy learning using virtual reality (VR) simulation. SETTING/DESIGN: In our surgical simulation laboratory, we compared students learning basic skills on a VR arthroscopy simulator after watching an expert video demonstration of VR arthroscopy tasks or a non-expert video demonstration of the same tasks to a Control group without video demonstration...
June 23, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28639869/economic-burden-of-inpatient-admission-of-ankle-fractures
#11
Justin D Stull, Suneel B Bhat, Justin M Kane, Steven M Raikin
BACKGROUND: Ankle fractures are among the most prevalent traumatic orthopaedic injuries. A large proportion of patients sustaining operative ankle fractures are admitted directly from the emergency department prior to operative management. In the authors' experience, however, many closed ankle injuries may be safely and effectively managed on an outpatient basis. The aim of this study was to characterize the economic impact of routine inpatient admission of ankle fractures. METHODS: A retrospective review of all outpatient ankle fracture surgery performed by a single foot and ankle fellowship-trained surgeon at a tertiary level academic center in 2012 was conducted to identify any patients requiring postoperative inpatient admission...
June 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/28614352/a-novel-iterative-mixed-model-to-remap-three-complex-orthopedic-traits-in-dogs
#12
Meng Huang, Jessica J Hayward, Elizabeth Corey, Susan J Garrison, Gabriela R Wagner, Ursula Krotscheck, Kei Hayashi, Peter A Schweitzer, George Lust, Adam R Boyko, Rory J Todhunter
Hip dysplasia (HD), elbow dysplasia (ED), and rupture of the cranial (anterior) cruciate ligament (RCCL) are the most common complex orthopedic traits of dogs and all result in debilitating osteoarthritis. We reanalyzed previously reported data: the Norberg angle (a quantitative measure of HD) in 921 dogs, ED in 113 cases and 633 controls, and RCCL in 271 cases and 399 controls and their genotypes at ~185,000 single nucleotide polymorphisms. A novel fixed and random model with a circulating probability unification (FarmCPU) function, with marker-based principal components and a kinship matrix to correct for population stratification, was used...
2017: PloS One
https://www.readbyqxmd.com/read/28607938/biomechanical-head-to-head-comparison-of-2-sutures-and-the-giftbox-versus-bunnell-techniques-for-midsubstance-achilles-tendon-ruptures
#13
Rufus O Van Dyke, Sejul A Chaudhary, Gregory Gould, Roman Trimba, Richard T Laughlin
BACKGROUND: Acute midsubstance Achilles tendon ruptures are a common orthopaedic problem for which the optimal repair technique and suture type remain controversial. Head-to-head comparisons of current fixation constructs are needed to establish which stitch/suture combination is most biomechanically favorable. HYPOTHESIS: Of the tested fixation constructs, Giftbox repairs with Fiberwire will exhibit superior stiffness and strength during biomechanical testing. STUDY DESIGN: Controlled laboratory study...
May 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28600218/systematic-review-of-patient-specific-surgical-simulation-toward-advancing-medical-education-%C3%A2
#14
Won Hyung A Ryu, Navjit Dharampal, Ahmed E Mostafa, Ehud Sharlin, Gail Kopp, William Bradley Jacobs, Robin John Hurlbert, Sonny Chan, Garnette R Sutherland
OBJECTIVE: Simulation-based education has been shown to be an effective tool to teach foundational technical skills in various surgical specialties. However, most of the current simulations are limited to generic scenarios and do not allow continuation of the learning curve beyond basic technical skills to prepare for more advanced expertise, such as patient-specific surgical planning. The objective of this study was to evaluate the current medical literature with respect to the utilization and educational value of patient-specific simulations for surgical training...
June 6, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28588107/staffs-and-managers-perceptions-of-how-and-when-discrete-event-simulation-modelling-can-be-used-as-a-decision-support-in-quality-improvement-a-focus-group-discussion-study-at-two-hospital-settings-in-sweden
#15
Helena Hvitfeldt-Forsberg, Pamela Mazzocato, Daniel Glaser, Christina Keller, Maria Unbeck
OBJECTIVE: To explore healthcare staffs' and managers' perceptions of how and when discrete event simulation modelling can be used as a decision support in improvement efforts. DESIGN: Two focus group discussions were performed. SETTING: Two settings were included: a rheumatology department and an orthopaedic section both situated in Sweden. PARTICIPANTS: Healthcare staff and managers (n=13) from the two settings. INTERVENTIONS: Two workshops were performed, one at each setting...
June 6, 2017: BMJ Open
https://www.readbyqxmd.com/read/28573966/learning-navigation-learning-with-navigation-a-review
#16
Jean-Yves Jenny, Frederic Picard
The goal of this review paper is to retrieve from the existing literature relevant information (1) about the learning curve of the currently existing navigation systems and (2) about the use of navigation system for teaching orthopaedic procedures. All studies reporting on the learning curve of navigation systems support the hypothesis that computer-navigated total knee arthroplasty (TKA) involves only a short learning curve and that beginners can obtain good results from the beginning of their experience, as navigation provides continuous feedback during all phases of the knee replacement surgery and allows for correcting any bone cut errors...
2017: SICOT-J
https://www.readbyqxmd.com/read/28552412/connecting-the-wrist-to-the-hand-a-simulation-study-exploring-changes-in-thumb-tip-endpoint-force-following-wrist-surgery
#17
Jennifer A Nichols, Michael S Bednar, Sarah J Wohlman, Wendy M Murray
The wrist is essential for hand function. Yet, due to the complexity of the wrist and hand, studies often examine their biomechanical features in isolation. This approach is insufficient for understanding links between orthopaedic surgery at the wrist and concomitant functional impairments at the hand. We hypothesize that clinical reports of reduced force production by the hand following wrist surgeries can be explained by the surgically-induced, biomechanical changes to the system, even when those changes are isolated to the wrist...
June 14, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28532092/cytocompatibility-studies-of-titania-doped-calcium-borosilicate-bioactive-glasses-in-vitro
#18
Rajkumar Samudrala, Abdul Azeem P, Vasudevarao Penugurti, Bramanandam Manavathi
The present study aims to elucidate the applications of Titania (TiO2) doped calcium borosilicate glass as a biocompatible material in regenerative orthopedic applications. In this context, we have examined the bioactivity of various concentrations of TiO2 doped glasses with the help of simulated body fluid (SBF). Cytocompatibility, cell proliferation, and protein expression studies revealed the potential candidature of TiO2 doped glasses on osteoblast cell lines (MG-63). We hypothesized that TiO2 doped calcium borosilicate glasses are most cytocompatible material for bone implants...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28523072/delayed-endothelial-progenitor-cell-therapy-promotes-bone-defect-repair-in-a-clinically-relevant-rat-model
#19
Brent D Bates, Charles Godbout, David J Ramnaraign, Emil H Schemitsch, Aaron Nauth
The repair of segmental bone defects remains a significant challenge for orthopaedic surgeons. Endothelial progenitor cells (EPCs) have successfully promoted the repair of acute defects in animal models; however, the ability of EPCs to induce the repair of chronic nonhealing defects, such as those often encountered clinically, has not been investigated. Therefore, the purpose of this study was to investigate the ability of EPCs delivered in delayed fashion to induce the repair of nonhealing defects in a clinically relevant model...
2017: Stem Cells International
https://www.readbyqxmd.com/read/28521380/-clinical-practical-examination-in-orthopaedic-teaching-who-is-the-ideal-examiner
#20
Peter Melcher, Andreas Roth, Mohamed Ghanem, Daisy Rotzoll
Background Medical curricula require an increasing amount of integrated clinical practical skills education. German medical faculties are increasingly implementing the OSCE (objective structured clinical examination) to test students' practical as well as communication skills. Teaching and assessment tools for practical skills include simulators and simulated patient scenarios, where peer-assisted teaching (PAT) is applied. Trained student tutors support this process. This study examines for the first time the use of PAT student tutors as examiners in an orthopaedic OSCE unit and the existence of possible differences in rating between faculty and PAT student tutors...
May 18, 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
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