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https://www.readbyqxmd.com/read/27895899/oxidatively-degradable-poly-thioketal-urethane-ceramic-composite-bone-cements-with-bone-like-strength
#1
Madison A P McEnery, Sichang Lu, Mukesh K Gupta, Katarzyna J Zienkiewicz, Joseph C Wenke, Kerem N Kalpakci, Daniel Shimko, Craig L Duvall, Scott A Guelcher
Synthetic bone cements are commonly used in orthopaedic procedures to aid in bone regeneration following trauma or disease. Polymeric cements like PMMA provide the mechanical strength necessary for orthopaedic applications, but they are not resorbable and do not integrate with host bone. Ceramic cements have a chemical composition similar to that of bone, but their brittle mechanical properties limit their use in weight-bearing applications. In this study, we designed oxidatively degradable, polymeric bone cements with mechanical properties suitable for bone tissue engineering applications...
2016: RSC Advances
https://www.readbyqxmd.com/read/27889088/osteoblast-cellular-activity-on-low-elastic-modulus-ti-24nb-4zr-8sn-alloy
#2
K C Nune, R D K Misra, S J Li, Y L Hao, R Yang
OBJECTIVES: Low modulus β-titanium alloys with non-toxic alloying elements are envisaged to provide good biocompatibility and alleviate the undesired stress shielding effect. The objective of this study is to fundamentally elucidate the biological response of novel high strength-low elastic modulus Ti2448 alloy through the study of bioactivity and osteoblast cell functions. METHODS: Characterization techniques such as SEM, EDX, XRD, and fluorescence microscopy were utilized to analyze the microstructure, morphology, chemical composition, and cell adhesion...
November 23, 2016: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/27829731/dynamic-thermal-acoustic-response-for-human-bone-materials-at-different-energy-levels-a-diagnosis-approach
#3
Ashok Kumar Thella, James Rizkalla, Neeraj Rathi, Monika Kakani, Ahdy Helmy, Paul Salama, Maher E Rizkalla
BACKGROUND: The non-invasive diagnostic approaches have gained high attention in recent years, utilizing high technology sensor systems, including infrared, microwave devices, acoustic transducers, etc. The patient safety, high resolution images, and reliability are among the driving forces toward high technology approaches. The thermal and acoustic responses of the materials may reflect the important research parameters such as penetration depth, power consumption, and temperature change used for the practical models of the system...
March 2017: Journal of Orthopaedics
https://www.readbyqxmd.com/read/27819644/patient-specific-instruments-for-complex-tumor-resection-reconstruction-surgery-within-the-pelvis-a-series-of-4-cases
#4
Eduard Cernat, Pierre-Louis Docquier, Laurent Paul, Xavier Banse, Ion-Bogdan Codorean
The pelvis bone resection-reconstruction surgery is one of the most challenging fields in orthopedics. Being applied for tumors, as for other complex reconstruction cases, this type of surgery needs careful planning and is time consuming, in order to obtain proper accuracy. Unfortunately not all the time the expected accuracy is met, with consequences for the patients. PSI proved to provide good cutting accuracy during simulated tumor surgery within the pelvis. This article present a series of 4 patients operated in our department between June 2014 and Mars 2015 for tumors resectionreconstructions...
2016: Chirurgia
https://www.readbyqxmd.com/read/27807113/breast-radiation-exposure-in-female-orthopaedic-surgeons
#5
Lindsey C Valone, Monique Chambers, Lisa Lattanza, Michelle A James
BACKGROUND: Breast cancer prevalence is higher among female orthopaedic surgeons compared with U.S. women. The most common breast cancer site, the upper outer quadrant (UOQ), may not be adequately shielded from intraoperative radiation. Factors associated with higher breast radiation exposure (protective apron size and type, surgeon position, and C-arm position) have yet to be established. METHODS: An anthropomorphic torso phantom, simulating the female surgeon, was placed adjacent to a standard operating table...
November 2, 2016: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/27801643/arthroscopic-skills-assessment-and-use-of-box-model-for-training-in-arthroscopic-surgery-using-sawbones-fast-workstation
#6
Saumitra Goyal, Mohamed Abdel Radi, Islam Karam-Allah Ramadan, Hatem Galal Said
PURPOSE: Arthroscopic skills training outside the operative room may decrease risks and errors by trainee surgeons. There is a need of simple objective method for evaluating proficiency and skill of arthroscopy trainees using simple bench model of arthroscopic simulator. The aim of this study is to correlate motor task performance to level of prior arthroscopic experience and establish benchmarks for training modules. METHODS: Twenty orthopaedic surgeons performed a set of tasks to assess a) arthroscopic triangulation, b) navigation, c) object handling and d) meniscus trimming using SAWBONES "FAST" arthroscopy skills workstation...
2016: SICOT-J
https://www.readbyqxmd.com/read/27796196/quantifying-range-of-motion-changes-across-4-simulated-measurements-of-the-glenohumeral-joint-posterior-capsule-an-exploratory-cadaver-study
#7
Amitabh Dashottar, John Borstad
Study Design Repeated-measures controlled laboratory cadaveric study. Background There is a lack of information about the most sensitive measure of glenohumeral joint posterior capsule length. Although maximum strains on the glenohumeral joint posterior capsule are observed in measurements combining glenohumeral joint flexion and internal rotation (IR), the range-of-motion (ROM) change after experimental contracture has never been compared across commonly used posterior capsular measurements. Objectives To evaluate the IR ROM change across 4 glenohumeral joint posterior capsule measurements after experimental capsule shrinkage using radiofrequency thermal energy...
December 2016: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/27785046/simulation-analysis-of-resource-flexibility-on-healthcare-processes
#8
Yusta W Simwita, Berit I Helgheim
PURPOSE: This paper uses discrete event simulation to explore the best resource flexibility scenario and examine the effect of implementing resource flexibility on different stages of patient treatment process. Specifically we investigate the effect of resource flexibility on patient waiting time and throughput in an orthopedic care process. We further seek to explore on how implementation of resource flexibility on patient treatment processes affects patient access to healthcare services...
2016: Journal of Multidisciplinary Healthcare
https://www.readbyqxmd.com/read/27777477/study-of-scattered-radiation-during-fluoroscopy-in-hip-surgery
#9
Oksana Lesyuk, Patrick Emmanuel Sousa, Sónia Isabel do Espirito Santo Rodrigues, António Fernando Abrantes, Rui Pedro Pereira de Almeida, João Pedro Pinheiro, Kevin Barros Azevedo, Luís Pedro Vieira Ribeiro
OBJECTIVE: To measure the scattered radiation dose at different positions simulating hip surgery. MATERIALS AND METHODS: We simulated fluoroscopy-assisted hip surgery in order to study the distribution of scattered radiation in the operating room. To simulate the patient, we used a anthropomorphic whole-body phantom, and we used an X-ray-specific detector to quantify the radiation. Radiographs were obtained with a mobile C-arm X-ray system in continuous scan mode, with the tube at 0º (configuration 1) or 90º (configuration 2)...
July 2016: Radiologia Brasileira
https://www.readbyqxmd.com/read/27770873/mechanical-and-degradation-properties-of-biodegradable-mg-strengthened-poly-lactic-acid-composite-through-plastic-injection-molding
#10
Muhammad Shoaib Butt, Jing Bai, Xiaofeng Wan, Chenglin Chu, Feng Xue, Hongyan Ding, Guanghong Zhou
Full biodegradable magnesium alloy (AZ31) strengthened poly-lactic acid (PLA) composite rods for potential application for bone fracture fixation were prepared by plastic injection process in this work. Their surface/interfacial morphologies, mechanical properties and vitro degradation were studied. In comparison with untreated Mg rod, porous MgO ceramic coating on Mg surface formed by Anodizing (AO) and micro-arc-oxidation (MAO)treatment can significantly improve the interfacial binding between outer PLA cladding and inner Mg rod due to the micro-anchoring action, leading to better mechanical properties and degradation performance of the composite rods...
January 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/27735977/biomechanical-and-cost-comparisons-of-near-far-and-pin-bar-constructs
#11
Augusta Whitney Kluk, Tina Zhang, Joseph P Russell, Hyunchul Kim, Adam H Hsieh, Robert V O'Toole
Orthopedic dogma states that external fixator stiffness is improved by placing 1 pin close to the fracture and 1 as distant as possible ("near-far"). This fixator construct is thought to be less expensive than placing pins a shorter distance apart and using "pin-bar" clamps that attach pins to outriggers. The authors therefore hypothesized that the near-far construct is stiffer and less expensive. They compared mechanical stiffness and costs of near-far and pin-bar constructs commonly used for temporary external fixation of femoral shaft fractures...
October 13, 2016: Orthopedics
https://www.readbyqxmd.com/read/27726454/rapidly-dissociated-autologous-meniscus-tissue-enhances-meniscus-healing-an-in-vitro-study
#12
Piya-On Numpaisal, Benjamin B Rothrauff, Riccardo Gottardi, Chung-Liang Chien, Rocky S Tuan
PURPOSE: Treatment of meniscus tears is a persistent challenge in orthopedics. Although cell therapies have shown promise in promoting fibrocartilage formation in in vitro and preclinical studies, clinical application has been limited by the paucity of autologous tissue and the need for ex vivo cell expansion. Rapid dissociation of the free edges of the anterior and posterior meniscus with subsequent implantation in a meniscus lesion may overcome these limitations. The purpose of this study was to explore the effect of rapidly dissociated meniscus tissue in enhancing neotissue formation in a radial meniscus tear, as simulated in an in vitro explant model...
October 11, 2016: Connective Tissue Research
https://www.readbyqxmd.com/read/27723229/the-development-and-error-analysis-of-a-kinematic-parameters-based-spatial-positioning-method-for-an-orthopedic-navigation-robot-system
#13
Baoqing Pei, Gang Zhu, Yu Wang, Huiting Qiao, Xiangqian Chen, Binbin Wang, Xiaoyun Li, Weijun Zhang, Wenyong Liu, Yubo Fan
BACKGROUND: Spatial positioning is the key function of a surgical navigation robot system, and accuracy is the most important performance index of such a system. METHODS: The kinematic parameters of a six degrees of freedom (DOF) robot arm were used to form the transformation from intraoperative fluoroscopy images to a robot's coordinate system without C-arm calibration and to solve the redundant DOF problem. The influences of three typical error sources and their combination on the final navigation error were investigated through Monte Carlo simulation...
October 9, 2016: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
https://www.readbyqxmd.com/read/27720405/construct-validity-assessment-of-the-learning-curve-and-experience-of-using-a-low-cost-arthroscopic-surgical-simulator
#14
Henry B Colaco, Katie Hughes, Eyiyemi Pearse, Magnus Arnander, Duncan Tennent
OBJECTIVE: We have developed a low-cost, portable shoulder simulator designed to train basic arthroscopic skills. This study aimed to establish the construct validity of the simulator by determining which parameters discriminated between experience levels and to assess the experience of using the simulator. DESIGN: Participants were given an introductory presentation and an untimed practice run of a 6-step triangulation task using hooks and rubber bands. A total of 6 consecutive attempts at the task were timed, and the number of times the participant looked at their hands during the task was recorded...
October 5, 2016: Journal of Surgical Education
https://www.readbyqxmd.com/read/27720337/a-mathematical-method-for-precisely-calculating-the-radiographic-angles-of-the-cup-after-total-hip-arthroplasty
#15
Jing-Xin Zhao, Xiu-Yun Su, Ruo-Xiu Xiao, Zhe Zhao, Li-Hai Zhang, Li-Cheng Zhang, Pei-Fu Tang
We established a mathematical method to precisely calculate the radiographic anteversion (RA) and radiographic inclination (RI) angles of the acetabular cup based on anterior-posterior (AP) pelvic radiographs after total hip arthroplasty. Using Mathematica software, a mathematical model for an oblique cone was established to simulate how AP pelvic radiographs are obtained and to address the relationship between the two-dimensional and three-dimensional geometry of the opening circle of the cup. In this model, the vertex was the X-ray beam source, and the generatrix was the ellipse in radiographs projected from the opening circle of the acetabular cup...
October 5, 2016: Medical Engineering & Physics
https://www.readbyqxmd.com/read/27717913/surface-phosphonation-enhances-hydroxyapatite-coating-adhesion-on-polyetheretherketone-and-its-osseointegration-potential
#16
Hesameddin Mahjoubi, Emily Buck, Praveena Manimunda, Reza Farivar, Richard Chromik, Monzur Murshed, Marta Cerruti
: Polyetheretherketone (PEEK) has excellent mechanical properties, biocompatibility, chemical resistance and radiolucency, making it suitable for use as orthopedic implants. However, its surface is hydrophobic and bioinert, and surface modification is required to improve its bioactivity. In this work, we showed that grafting phosphonate groups via diazonium chemistry enhances the bioactivity of PEEK. Decreased contact angle indicated reduced hydrophobicity as a result of the treatment and X-ray photoelectron spectroscopy (XPS) confirmed the attachment of phosphonate groups to the surface...
October 4, 2016: Acta Biomaterialia
https://www.readbyqxmd.com/read/27716636/evaluation-of-amorphous-magnesium-phosphate-amp-based-non-exothermic-orthopedic-cements
#17
Elham Babaie, Boren Lin, Vijay K Goel, Sarit B Bhaduri
This paper reports for the first time the development of a biodegradable, non-exothermic, self-setting orthopedic cement composition based on amorphous magnesium phosphate (AMP). The occurrence of undesirable exothermic reactions was avoided through using AMP as the solid precursor. The phenomenon of self-setting with optimum rheology is achieved by incorporating a water soluble biocompatible/biodegradable polymer, polyvinyl alcohol (PVA). Additionally, PVA enables a controlled growth of the final phase via a biomimetic process...
October 7, 2016: Biomedical Materials
https://www.readbyqxmd.com/read/27712189/a-computational-model-of-osteochondral-defect-repair-following-implantation-of-stem-cell-laden-multiphase-scaffolds
#18
Adam O'Reilly, Daniel John Kelly
Developing successful tissue engineering strategies requires an understanding of how cells within an implanted scaffold interacts with the host environment. The objective of this study was to use a computational mechanobiological model to explore how the design of a cell laden scaffold influences the spatial formation of cartilage and bone within an osteochondral defect. Tissue differentiation was predicted using a previously developed model in which cell fate depends on the local oxygen tension and the mechanical environment within a damaged joint...
October 6, 2016: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/27699631/estimating-the-societal-benefits-of-tha-after-accounting-for-work-status-and-productivity-a-markov-model-approach
#19
Lane Koenig, Qian Zhang, Matthew S Austin, Berna Demiralp, Thomas K Fehring, Chaoling Feng, Richard C Mather, Jennifer T Nguyen, Asha Saavoss, Bryan D Springer, Adolph J Yates
BACKGROUND: Demand for total hip arthroplasty (THA) is high and expected to continue to grow during the next decade. Although much of this growth includes working-aged patients, cost-effectiveness studies on THA have not fully incorporated the productivity effects from surgery. QUESTIONS/PURPOSES: We asked: (1) What is the expected effect of THA on patients' employment and earnings? (2) How does accounting for these effects influence the cost-effectiveness of THA relative to nonsurgical treatment? METHODS: Taking a societal perspective, we used a Markov model to assess the overall cost-effectiveness of THA compared with nonsurgical treatment...
December 2016: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/27677290/are-peek-on-ceramic-bearings-an-option-for-total-disc-arthroplasty-an-in-vitro-tribology-study
#20
Ryan Siskey, Lauren Ciccarelli, Melissa K C Lui, Steven M Kurtz
BACKGROUND: Most contemporary total disc replacements (TDRs) use conventional orthopaedic bearing couples such as ultrahigh-molecular-weight polyethylene (polyethylene) and cobalt-chromium (CoCr). Cervical total disc replacements incorporating polyetheretherketone (PEEK) bearings (specifically PEEK-on-PEEK bearings) have been previously investigated, but little is known about PEEK-on-ceramic bearings for TDR. QUESTIONS/PURPOSES: (1) What is the tribologic behavior of a PEEK-on-ceramic bearing for cervical TDR under idealized, clean wear test conditions? (2) How does the PEEK-on-ceramic design perform under impingement conditions? (3) How is the PEEK-on-ceramic bearing affected by abrasive wear? (4) Is the particle morphology from PEEK-on-ceramic bearings for TDRs affected by adverse wear scenarios? METHODS: PEEK-on-ceramic cervical TDR bearings were subjected to a 10 million cycle ideal wear test based on ASTM F2423 and ISO 181912-1 using a six-station spine wear simulator (MTS, Eden Prairie, MN, USA) with 5 g/L bovine serum concentration at 23° ± 2° C (ambient temperature)...
November 2016: Clinical Orthopaedics and related Research
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