keyword
https://read.qxmd.com/read/38589537/measuring-practice-preference-variation-for-quality-improvement-in-neonatal-respiratory-care
#1
JOURNAL ARTICLE
Helen Healy, Emily Whitesel, Wenyang Mao, Colby L Day, Thomas G Murphy, Clara H Song, Patricia K Williams, Sandhya S Brachio, Parul Cham, Rebecca J Vartanian, Steven Chin, Puneet Arora, Matthew Bizzarro, David W Sink, John A F Zupancic, Munish Gupta
OBJECTIVES: The authors sought to measure and compare practice preference variation in neonatal respiratory care within and between neonatal intensive care units (NICUs) using the Neonatology Survey of Interdisciplinary Groups in Healthcare Tool (NSIGHT). STUDY DESIGN: Eleven NICUs completed the NSIGHT between 2019 and 2021. Net preference was measured by mean response; agreement was ranked by standard distribution of response values. Heat maps showed comparisons between NICUs and disciplines...
April 8, 2024: Journal of Perinatology: Official Journal of the California Perinatal Association
https://read.qxmd.com/read/38409330/the-diagnostic-utility-of-obtaining-two-blood-cultures-for-the-diagnosis-of-early-onset-sepsis-in-neonates
#2
JOURNAL ARTICLE
Noa Fleiss, Veronika Shabanova, Thomas S Murray, Patrick G Gallagher, Matthew J Bizzarro
No abstract text is available yet for this article.
February 26, 2024: Journal of Perinatology: Official Journal of the California Perinatal Association
https://read.qxmd.com/read/38351269/environmental-drivers-of-biogeography-and-community-structure-in-a-mid-atlantic-estuary
#3
JOURNAL ARTICLE
Haley A Oleynik, Joseph J Bizzarro, Edward A Hale, Aaron B Carlisle
Estuaries include some of the most productive yet anthropogenically impacted marine ecosystems on the planet, and provide critical habitat to many ecologically and economically important marine species. In order to elucidate ecological function in estuaries, we must understand what factors drive community dynamics. Delaware Bay is the third largest estuary in the United States and hosts over 200 species of migrant and resident fishes and invertebrates. The Delaware Division of Fish and Wildlife has conducted two long-term trawl surveys at monthly intervals in Delaware Bay since 1966...
February 14, 2024: Oecologia
https://read.qxmd.com/read/38241310/an-updated-end-to-end-ecosystem-model-of-the-northern-california-current-reflecting-ecosystem-changes-due-to-recent-marine-heatwaves
#4
JOURNAL ARTICLE
Dylan G E Gomes, James J Ruzicka, Lisa G Crozier, David D Huff, Elizabeth M Phillips, Pierre-Yves Hernvann, Cheryl A Morgan, Richard D Brodeur, Jen E Zamon, Elizabeth A Daly, Joseph J Bizzarro, Jennifer L Fisher, Toby D Auth
The Northern California Current is a highly productive marine upwelling ecosystem that is economically and ecologically important. It is home to both commercially harvested species and those that are federally listed under the U.S. Endangered Species Act. Recently, there has been a global shift from single-species fisheries management to ecosystem-based fisheries management, which acknowledges that more complex dynamics can reverberate through a food web. Here, we have integrated new research into an end-to-end ecosystem model (i...
2024: PloS One
https://read.qxmd.com/read/38155534/analysis-of-cation-composition-in-dolomites-on-the-intact-particles-sampled-from-asteroid-ryugu
#5
JOURNAL ARTICLE
Mayu Morita, Hiroharu Yui, Shu-Hei Urashima, Morihiko Onose, Shintaro Komatani, Izumi Nakai, Yoshinari Abe, Yasuko Terada, Hisashi Homma, Kazuko Motomura, Kiyohiro Ichida, Tetsuya Yokoyama, Kazuhide Nagashima, Jérôme Aléon, Conel M O'D Alexander, Sachiko Amari, Yuri Amelin, Ken-Ichi Bajo, Martin Bizzarro, Audrey Bouvier, Richard W Carlson, Marc Chaussidon, Byeon-Gak Choi, Nicolas Dauphas, Andrew M Davis, Wataru Fujiya, Ryota Fukai, Ikshu Gautam, Makiko K Haba, Yuki Hibiya, Hiroshi Hidaka, Peter Hoppe, Gary R Huss, Tsuyoshi Iizuka, Trevor R Ireland, Akira Ishikawa, Shoichi Itoh, Noriyuki Kawasaki, Noriko T Kita, Kouki Kitajima, Thorsten Kleine, Sasha Krot, Ming-Chang Liu, Yuki Masuda, Frédéric Moynier, Ann Nguyen, Larry Nittler, Andreas Pack, Changkun Park, Laurette Piani, Liping Qin, Tommaso Di Rocco, Sara S Russell, Naoya Sakamoto, Maria Schönbächler, Lauren Tafla, Haolan Tang, Kentaro Terada, Tomohiro Usui, Sohei Wada, Meenakshi Wadhwa, Richard J Walker, Katsuyuki Yamashita, Qing-Zhu Yin, Shigekazu Yoneda, Edward D Young, Ai-Cheng Zhang, Tomoki Nakamura, Hiroshi Naraoka, Takaaki Noguchi, Ryuji Okazaki, Kanako Sakamoto, Hikaru Yabuta, Masanao Abe, Akiko Miyazaki, Aiko Nakato, Masahiro Nishimura, Tatsuaki Okada, Toru Yada, Kasumi Yogata, Satoru Nakazawa, Takanao Saiki, Satoshi Tanaka, Fuyuto Terui, Yuichi Tsuda, Sei-Ichiro Watanabe, Makoto Yoshikawa, Shogo Tachibana, Hisayoshi Yurimoto
Characterization of the elemental distribution of samples with rough surfaces has been strongly desired for the analysis of various natural and artificial materials. Particularly for pristine and rare analytes with micrometer sizes embedded on specimen surfaces, non-invasive and matrix effect-free analysis is required without surface polishing treatment. To satisfy these requirements, we proposed a new method employing the sequential combination of two imaging modalities, i.e., microenergy-dispersive X-ray fluorescence (micro-XRF) and Raman micro-spectroscopy...
December 28, 2023: Analytical Chemistry
https://read.qxmd.com/read/38102626/pulmonary-function-assessment-after-covid-19-in-vaccinated-healthcare-workers
#6
JOURNAL ARTICLE
Lorenzo Ippoliti, Luca Coppeta, Giuseppina Somma, Giuseppe Bizzarro, Francesco Borelli, Teresa Crispino, Cristiana Ferrari, Ilaria Iannuzzi, Andrea Mazza, Agostino Paolino, Andrea Magrini, Antonio Pietroiusti
COVID-19 typically presents with flu-like symptoms due to the viral infection itself. The most severe cases are characterised by lung damage, an important factor in fatal outcome due to alveolar damage. In some cases, patients develop a long COVID with persistent symptoms of chest pain and fatigue. Causes, including organ damage or inflammation, are being investigated. Clinical outcomes are variable and permanent lung damage is not fully understood, while vaccination is effective against severe infection but its effect on respiratory function in mild cases remains uncertain...
December 15, 2023: Journal of Occupational Medicine and Toxicology
https://read.qxmd.com/read/37939187/water-circulation-in-ryugu-asteroid-affected-the-distribution-of-nucleosynthetic-isotope-anomalies-in-returned-sample
#7
JOURNAL ARTICLE
Tetsuya Yokoyama, Meenakshi Wadhwa, Tsuyoshi Iizuka, Vinai Rai, Ikshu Gautam, Yuki Hibiya, Yuki Masuda, Makiko K Haba, Ryota Fukai, Rebekah Hines, Nicole Phelan, Yoshinari Abe, Jérôme Aléon, Conel M O'D Alexander, Sachiko Amari, Yuri Amelin, Ken-Ichi Bajo, Martin Bizzarro, Audrey Bouvier, Richard W Carlson, Marc Chaussidon, Byeon-Gak Choi, Nicolas Dauphas, Andrew M Davis, Tommaso Di Rocco, Wataru Fujiya, Hiroshi Hidaka, Hisashi Homma, Peter Hoppe, Gary R Huss, Kiyohiro Ichida, Trevor Ireland, Akira Ishikawa, Shoichi Itoh, Noriyuki Kawasaki, Noriko T Kita, Koki Kitajima, Thorsten Kleine, Shintaro Komatani, Alexander N Krot, Ming-Chang Liu, Kevin D McKeegan, Mayu Morita, Kazuko Motomura, Frédéric Moynier, Izumi Nakai, Kazuhide Nagashima, Ann Nguyen, Larry Nittler, Morihiko Onose, Andreas Pack, Changkun Park, Laurette Piani, Liping Qin, Sara Russell, Naoya Sakamoto, Maria Schönbächler, Lauren Tafla, Haolan Tang, Kentaro Terada, Yasuko Terada, Tomohiro Usui, Sohei Wada, Richard J Walker, Katsuyuki Yamashita, Qing-Zhu Yin, Shigekazu Yoneda, Edward D Young, Hiroharu Yui, Ai-Cheng Zhang, Tomoki Nakamura, Hiroshi Naraoka, Takaaki Noguchi, Ryuji Okazaki, Kanako Sakamoto, Hikaru Yabuta, Masanao Abe, Akiko Miyazaki, Aiko Nakato, Masahiro Nishimura, Tatsuaki Okada, Toru Yada, Kasumi Yogata, Satoru Nakazawa, Takanao Saiki, Satoshi Tanaka, Fuyuto Terui, Yuichi Tsuda, Sei-Ichiro Watanabe, Makoto Yoshikawa, Shogo Tachibana, Hisayoshi Yurimoto
Studies of material returned from Cb asteroid Ryugu have revealed considerable mineralogical and chemical heterogeneity, stemming primarily from brecciation and aqueous alteration. Isotopic anomalies could have also been affected by delivery of exogenous clasts and aqueous mobilization of soluble elements. Here, we show that isotopic anomalies for mildly soluble Cr are highly variable in Ryugu and CI chondrites, whereas those of Ti are relatively uniform. This variation in Cr isotope ratios is most likely due to physicochemical fractionation between 54 Cr-rich presolar nanoparticles and Cr-bearing secondary minerals at the millimeter-scale in the bulk samples, likely due to extensive aqueous alteration in their parent bodies that occurred [Formula: see text] after Solar System birth...
November 10, 2023: Science Advances
https://read.qxmd.com/read/37877650/myelomatous-meningitis-diagnosed-by-cerebrospinal-fluid-cytology-examination
#8
JOURNAL ARTICLE
Tommaso Bizzarro, Giovanna De Marco, Michele Romoli, Lina Paolucci, Federico Morigi, Marco Longoni, Daniela Bartolini
Myelomatous meningitis diagnosed by CSF cytology. The combined use of cytology with immunocytochemistry can identify the presence of multiple myeloma cells in cerebrospinal fluid specimens.
October 25, 2023: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://read.qxmd.com/read/37541286/a-top-down-proteomic-approach-reveals-a-salivary-protein-profile-able-to-classify-parkinson-s-disease-with-respect-to-alzheimer-s-disease-patients-and-to-healthy-controls
#9
JOURNAL ARTICLE
Cristina Contini, Laura Fadda, Greca Lai, Carla Masala, Alessandra Olianas, Massimo Castagnola, Irene Messana, Federica Iavarone, Alessandra Bizzarro, Carlo Masullo, Paolo Solla, Giovanni Defazio, Barbara Manconi, Giacomo Diaz, Tiziana Cabras
Parkinson's disease (PD) is a complex neurodegenerative disease with motor and non-motor symptoms. Diagnosis is complicated by lack of reliable biomarkers. To individuate peptides and/or proteins with diagnostic potential for early diagnosis, severity and discrimination from similar pathologies, the salivary proteome in 36 PD patients was investigated in comparison with 36 healthy controls (HC) and 35 Alzheimer's disease (AD) patients. A top-down platform based on HPLC-ESI-IT-MS allowed characterizing and quantifying intact peptides, small proteins and their PTMs (overall 51)...
August 4, 2023: Proteomics
https://read.qxmd.com/read/37500662/a-multi-predator-trophic-database-for-the-california-current-large-marine-ecosystem
#10
JOURNAL ARTICLE
Joseph J Bizzarro, Lynn Dewitt, Brian K Wells, K Alexandra Curtis, Jarrod A Santora, John C Field
The California Current Trophic Database (CCTD) was developed at NOAA Southwest Fisheries Science Center in collaboration with numerous diet data contributors. We compiled the CCTD from twenty-four data sets, representing both systematic collections and directed trophic studies. Diet composition data, including stomach and scat samples, were obtained from 105,694 individual predators among 143 taxa collected throughout the California Current Large Marine Ecosystem (CCLME) from 1967-2019. Predator taxa consist of squids (n = 5), elasmobranchs (n = 13), bony fishes (n = 118), and marine mammals (n = 7)...
July 27, 2023: Scientific Data
https://read.qxmd.com/read/37495699/earth-s-evolving-geodynamic-regime-recorded-by-titanium-isotopes
#11
JOURNAL ARTICLE
Zhengbin Deng, Martin Schiller, Matthew G Jackson, Marc-Alban Millet, Lu Pan, Katrine Nikolajsen, Nikitha S Saji, Dongyang Huang, Martin Bizzarro
Earth's mantle has a two-layered structure, with the upper and lower mantle domains separated by a seismic discontinuity at about 660 km (refs. 1,2 ). The extent of mass transfer between these mantle domains throughout Earth's history is, however, poorly understood. Continental crust extraction results in Ti-stable isotopic fractionation, producing isotopically light melting residues3-7 . Mantle recycling of these components can impart Ti isotope variability that is trackable in deep time. We report ultrahigh-precision 49 Ti/47 Ti ratios for chondrites, ancient terrestrial mantle-derived lavas ranging from 3...
July 26, 2023: Nature
https://read.qxmd.com/read/37492442/neuropsychological-measures-of-post-covid-19-cognitive-status
#12
JOURNAL ARTICLE
Alessandra Lauria, Angelo Carfì, Francesca Benvenuto, Giulia Bramato, Francesca Ciciarello, Sara Rocchi, Elisabetta Rota, Andrea Salerno, Leonardo Stella, Marcello Tritto, Antonella Di Paola, Cristina Pais, Matteo Tosato, Delfina Janiri, Gabriele Sani, Rita Lo Monaco, Francesco C Pagano, Massimo Fantoni, Roberto Bernabei, Francesco Landi, Alessandra Bizzarro
BACKGROUND: COVID-19 may result in persistent symptoms in the post-acute phase, including cognitive and neurological ones. The aim of this study is to investigate the cognitive and neurological features of patients with a confirmed diagnosis of COVID-19 evaluated in the post-acute phase through a direct neuropsychological evaluation. METHODS: Individuals recovering from COVID-19 were assessed in an out-patient practice with a complete neurological evaluation and neuropsychological tests (Mini-Mental State Examination; Rey Auditory Verbal Test, Multiple Feature Target Cancellation Test, Trial Making Test, Digit Span Forward and Backward, and Frontal Assessment Battery)...
2023: Frontiers in Psychology
https://read.qxmd.com/read/37450600/abundant-presolar-grains-and-primordial-organics-preserved-in-carbon-rich-exogenous-clasts-in-asteroid-ryugu
#13
JOURNAL ARTICLE
Ann N Nguyen, Prajkta Mane, Lindsay P Keller, Laurette Piani, Yoshinari Abe, Jérôme Aléon, Conel M O'D Alexander, Sachiko Amari, Yuri Amelin, Ken-Ichi Bajo, Martin Bizzarro, Audrey Bouvier, Richard W Carlson, Marc Chaussidon, Byeon-Gak Choi, Nicolas Dauphas, Andrew M Davis, Tommaso Di Rocco, Wataru Fujiya, Ryota Fukai, Ikshu Gautam, Makiko K Haba, Yuki Hibiya, Hiroshi Hidaka, Hisashi Homma, Peter Hoppe, Gary R Huss, Kiyohiro Ichida, Tsuyoshi Iizuka, Trevor R Ireland, Akira Ishikawa, Shoichi Itoh, Noriyuki Kawasaki, Noriko T Kita, Kouki Kitajima, Thorsten Kleine, Shintaro Komatani, Alexander N Krot, Ming-Chang Liu, Yuki Masuda, Kevin D McKeegan, Mayu Morita, Kazuko Motomura, Frédéric Moynier, Izumi Nakai, Kazuhide Nagashima, David Nesvorný, Larry Nittler, Morihiko Onose, Andreas Pack, Changkun Park, Liping Qin, Sara S Russell, Naoya Sakamoto, Maria Schönbächler, Lauren Tafla, Haolan Tang, Kentaro Terada, Yasuko Terada, Tomohiro Usui, Sohei Wada, Meenakshi Wadhwa, Richard J Walker, Katsuyuki Yamashita, Qing-Zhu Yin, Tetsuya Yokoyama, Shigekazu Yoneda, Edward D Young, Hiroharu Yui, Ai-Cheng Zhang, Tomoki Nakamura, Hiroshi Naraoka, Takaaki Noguchi, Ryuji Okazaki, Kanako Sakamoto, Hikaru Yabuta, Masanao Abe, Akiko Miyazaki, Aiko Nakato, Masahiro Nishimura, Tatsuaki Okada, Toru Yada, Kasumi Yogata, Satoru Nakazawa, Takanao Saiki, Satoshi Tanaka, Fuyuto Terui, Yuichi Tsuda, Sei-Ichiro Watanabe, Makoto Yoshikawa, Shogo Tachibana, Hisayoshi Yurimoto
Preliminary analyses of asteroid Ryugu samples show kinship to aqueously altered CI (Ivuna-type) chondrites, suggesting similar origins. We report identification of C-rich, particularly primitive clasts in Ryugu samples that contain preserved presolar silicate grains and exceptional abundances of presolar SiC and isotopically anomalous organic matter. The high presolar silicate abundance (104 ppm) indicates that the clast escaped extensive alteration. The 5 to 10 times higher abundances of presolar SiC (~235 ppm), N-rich organic matter, organics with N isotopic anomalies (1...
July 14, 2023: Science Advances
https://read.qxmd.com/read/37341216/akt-inhibition-interferes-with-the-expression-of-immune-checkpoint-proteins-and-increases-nk-induced-killing-of-hl60-aml-cells
#14
JOURNAL ARTICLE
Sofia Mônaco Gama, Vanessa Araújo Varela, Natalia Mazini Ribeiro, Bruna Bizzarro, Camila Hernandes, Thiago Pinheiro Arrais Aloia, Mariane Tami Amano, Welbert Oliveira Pereira
OBJECTIVE: To determine the role of the AKT pathway in the regulating of natural Killer-induced apoptosis of acute myeloid leukemia cells and to characterize the associated molecular mechanisms. METHODS: BALB/c nude mice were injected with HL60 cells to induce a xenogenic model of subcutaneous leukemic tumors. Mice were treated with perifosine, and their spleens were analyzed using biometry, histopathology, and immunohistochemistry. Gene expression analysis in leukemia cells was performed by real-time PCR...
2023: Einstein
https://read.qxmd.com/read/37316662/silicon-isotope-constraints-on-terrestrial-planet-accretion
#15
JOURNAL ARTICLE
Isaac J Onyett, Martin Schiller, Georgy V Makhatadze, Zhengbin Deng, Anders Johansen, Martin Bizzarro
Understanding the nature and origin of the precursor material to terrestrial planets is key to deciphering the mechanisms and timescales of planet formation1 . Nucleosynthetic variability among rocky Solar System bodies can trace the composition of planetary building blocks2-5 . Here we report the nucleosynthetic composition of silicon (μ30 Si), the most abundant refractory planet-building element, in primitive and differentiated meteorites to identify terrestrial planet precursors. Inner Solar System differentiated bodies, including Mars, record μ30 Si deficits of -11...
July 2023: Nature
https://read.qxmd.com/read/37109328/use-of-first-line-oral-analgesics-during-and-after-covid-19-results-from-a-survey-on-a-sample-of-italian-696-covid-19-survivors-with-post-acute-symptoms
#16
JOURNAL ARTICLE
Vincenzo Galluzzo, Maria Beatrice Zazzara, Francesca Ciciarello, Matteo Tosato, Alessandra Bizzarro, Annamaria Paglionico, Valentina Varriano, Elisa Gremese, Riccardo Calvani, Francesco Landi
Background-Analgesics could be used to manage painful symptoms during and after COVID-19. Materials and methods-Persistence of painful symptoms was assessed during and after COVID-19 in a sample of patients admitted to a post-acute COVID-19 outpatient service in Rome, Italy. Data on type and frequency of use of first-line analgesics were collected. Pain severity was evaluated with a numeric rating scale (NRS) from 0 to 10. Results-Mean age of 696 participants was 57.1 ± 20.3 years and 61.7% were women...
April 20, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/36983903/characterization-of-cystatin-b-interactome-in-saliva-from-healthy-elderly-and-alzheimer-s-disease-patients
#17
JOURNAL ARTICLE
Cristina Contini, Simone Serrao, Barbara Manconi, Alessandra Olianas, Federica Iavarone, Giulia Guadalupi, Irene Messana, Massimo Castagnola, Carlo Masullo, Alessandra Bizzarro, Christoph W Turck, Giuseppina Maccarrone, Tiziana Cabras
Cystatin B is a small, multifunctional protein involved in the regulation of inflammation, innate immune response, and neuronal protection and found highly abundant in the brains of patients with Alzheimer's disease (AD). Recently, our study demonstrated a significant association between the level of salivary cystatin B and AD. Since the protein is able to establish protein-protein interaction (PPI) in different contexts and aggregation-prone proteins and the PPI networks are relevant for AD pathogenesis, and due to the relevance of finding new AD markers in peripheral biofluids, we thought it was interesting to study the possible involvement of cystatin B in PPIs in saliva and to evaluate differences and similarities between AD and age-matched elderly healthy controls (HC)...
March 10, 2023: Life
https://read.qxmd.com/read/36874263/are-we-essential-or-sacrificial-the-effects-of-felt-public-gratitude-on-essential-worker-recovery-activities-during-covid-19
#18
JOURNAL ARTICLE
Hee Young Kim, Sijun Kim, Taeya M Howell, Sarah P Doyle, Nathan C Pettit, Michael Bizzarro
COVID-19 has been characterized by unprecedented levels of public gratitude to some, but not all, essential workers. In this research, we integrate insights from the stigmatized occupations and gratitude literature to build theory on the positive and negative relationships between such displays of public gratitude and essential workers' recovery activities. We argue that felt public gratitude positively relates to adaptive recovery activities (e.g., exercise) and negatively relates to maladaptive recovery activities (e...
March 2023: Social Psychological and Personality Science
https://read.qxmd.com/read/36673059/immunohistochemistry-for-claudin-4-and-bap1-in-the-differential-diagnosis-between-sarcomatoid-carcinoma-and-sarcomatoid-mesothelioma
#19
JOURNAL ARTICLE
Lina Zuccatosta, Tommaso Bizzarro, Giulio Rossi, Graziana Gallo, Stefano Gasparini, Andrea Ambrosini-Spaltro
(1) Background. In the differential diagnosis between sarcomatoid carcinoma (SC) and sarcomatoid mesothelioma (SM), we aimed to investigate the role of Claudin-4 and BAP1, a panel recently used to distinguish conventional carcinoma from epithelioid mesothelioma. (2) Methods. We collected 41 surgical pleural biopsies of SM, 46 surgical resections of SC from different sites and 49 pleural biopsies of normal/hyperplastic mesothelium. All the cases were tested for Claudin-4 and BAP1 using immunohistochemistry. The statistical calculations of the sensitivity, specificity and positive and negative predictive values were performed...
January 9, 2023: Diagnostics
https://read.qxmd.com/read/36625072/reducing-mrsa-infection-in-a-new-nicu-during-the-covid-19-pandemic
#20
JOURNAL ARTICLE
Renee E Barrett, Noa Fleiss, Caitlin Hansen, Melissa M Campbell, Michelle Rychalsky, Christina Murdzek, Kathy Krechevsky, Meaghan Abbott, Terese Allegra, Beth Blazevich, Louise Dunphy, Amy Fox, Tracy Gambardella, Lindsey Garcia, Natalie Grimm, Amy Scoffone, Matthew J Bizzarro, Thomas S Murray
BACKGROUND AND OBJECTIVES: Methicillin-resistant Staphylococcus aureus (MRSA) is prevalent in most NICUs, with a high rate of skin colonization and subsequent invasive infections among hospitalized neonates. The effectiveness of interventions designed to reduce MRSA infection in the NICU during the coronavirus disease 2019 (COVID-19) pandemic has not been characterized. METHODS: Using the Institute for Healthcare Improvement's Model for Improvement, we implemented several process-based infection prevention strategies to reduce invasive MRSA infections at our level IV NICU over 24 months...
January 10, 2023: Pediatrics
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