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https://www.readbyqxmd.com/read/29166669/frequency-of-five-disease-causing-genetic-mutations-in-a-large-mixed-breed-dog-population-2011-2012
#1
Sharon Zierath, Angela M Hughes, Neale Fretwell, Mark Dibley, Kari J Ekenstedt
BACKGROUND: A large and growing number of inherited genetic disease mutations are now known in the dog. Frequencies of these mutations are typically examined within the breed of discovery, possibly in related breeds, but nearly always in purebred dogs. No report to date has examined the frequencies of specific genetic disease mutations in a large population of mixed-breed dogs. Further, veterinarians and dog owners typically dismiss inherited/genetic diseases as possibilities for health problems in mixed-breed dogs, assuming hybrid vigor will guarantee that single-gene disease mutations are not a cause for concern...
2017: PloS One
https://www.readbyqxmd.com/read/29166415/prognosis-of-type-1-autoimmune-pancreatitis-after-corticosteroid-therapy-induced-remission-in-terms-of-relapse-and-diabetes-mellitus
#2
Masaki Miyazawa, Hajime Takatori, Tetsuro Shimakami, Kazunori Kawaguchi, Kazuya Kitamura, Kuniaki Arai, Koichiro Matsuda, Taku Sanada, Takeshi Urabe, Katsuhisa Inamura, Takashi Kagaya, Hideki Mizuno, Uichiro Fuchizaki, Taro Yamashita, Yoshio Sakai, Tatsuya Yamashita, Eishiro Mizukoshi, Masao Honda, Shuichi Kaneko
BACKGROUND AND AIM: Relapse and diabetes mellitus (DM) are major problems for the prognosis of autoimmune pancreatitis (AIP). We examined the prognosis of type 1 AIP after corticosteroid therapy (CST)-induced remission in terms of relapse and DM. METHODS: The study enrolled 82 patients diagnosed with type 1 AIP who achieved remission with CST. We retrospectively evaluated the relapse rate in terms of the administration period of CST, clinical factors associated with relapse, and the temporal change in glucose tolerance...
2017: PloS One
https://www.readbyqxmd.com/read/29166253/hepatitis-c-virus-patients-risk-factors-and-knowledge-in-an-urban-clinic-providing-wound-care
#3
Barbara Pieper, Katharine Sickon
INTRODUCTION: Affecting about 3.2 million people in the United States, hepatitis C virus (HCV) is the primary cause of chronic liver disease and a global health challenge. Hepatitis C virus can affect the functioning of the liver, the health of the person, and thus wound healing. OBJECTIVE: This quality project explores risk factors of HCV; self-reported screening, occurrence, and treatment; and knowledge of HCV in patients seeking wound care in an urban clinic...
November 20, 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/29166194/the-effects-of-music-therapy-on-the-physiological-response-of-asthmatic-children-receiving-inhalation-therapy
#4
Riau Roslita, Nani Nurhaeni, Dessie Wanda
The clinical manifestation of asthma in children can interfere with their daily activities. Music therapy may become one of the alternative approaches to making children feel comfortable during inhalation therapy. The aim of the study was to identify the effects of music therapy on the physiological response of asthmatic preschool and school-age children receiving inhalation therapy. This study used a quasi-experimental, nonequivalent control group with a pre-test-post-test design. The 44 respondents consisted of preschool and school-age children assigned to intervention and control groups...
2017: Compr Child Adolesc Nurs
https://www.readbyqxmd.com/read/29165965/using-teams-to-improve-outcomes-and-performance
#5
Beth Ulrich, Nancy Manning Crider
Mastering the use of teams in healthcare organizations can maximize outcomes and optimize the use of resources. Most work in healthcare organizations is done by teams, whether it's the clinical team taking care of patients on a unit, the leadership team accountable for operations of the organization, or a team formed to solve a specific problem, improve quality, or plan an event. Effective teams make organizations successful; ineffective teams can create more problems than they solve. This article describes how to successfully use the power of teams within the healthcare setting, create and develop teams, be a team leader or member, create conditions for team effectiveness and high performance, and provide team training...
March 2017: Nephrology Nursing Journal: Journal of the American Nephrology Nurses' Association
https://www.readbyqxmd.com/read/29165943/-abdominal-wall-pain-the-%C3%A2-anterior-cutaneous-nerve-entrapment-syndrom-%C3%A2
#6
Jonathan Margalith, Reza Kehtari
Abdominal wall pain is a poorly recognized clinical problem and ofently misdiagnosed. It results in inappropriate diagnostic testing, unsatisfactory treatments and considerable costs. However, chronic abdominal wall pain can be easily diagnosed by a precise physical examination and can be rapidly and efficiently treated. Awareness of knowing criteria of the diagnosis is important but their validity needs to be evaluated in additional studies.
November 22, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/29165852/capturing-and-missing-the-patient-s-story-through-outcome-measures-a-thematic-comparison-of-patient-generated-items-in-psychlops-with-core-om-and-phq-9
#7
Célia Md Sales, Inês Td Neves, Paula G Alves, Mark Ashworth
BACKGROUND: There is increasing interest in individualized patient-reported outcome measures (I-PROMS), where patients themselves indicate the specific problems they want to address in therapy and these problems are used as items within the outcome measurement tool. OBJECTIVE: This paper examined the extent to which 279 items reported in an I-PROM (PSYCHLOPS) added qualitative information which was not captured by two well-established outcome measures (CORE-OM and PHQ-9)...
November 22, 2017: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/29165420/-clinical-features-and-diagnosis-of-diabetic-polyneuropathy
#8
S E Avetisov, N A Chernenkova, Z V Surnina
Diabetic polyneuropathy (DPN) is a serious complication of diabetes that leads to early disability in patients if late diagnosed. There has been a lot of research into pathophysiological mechanisms of nerve fiber damage and risk factors for neurological complications of diabetes. Early diagnosis of the latter is quite a challenge and, thus, the problem of finding more reliable diagnostic modalities is rather pressing. In this review, an interdisciplinary approach to the said problem, high-end diagnostic methods, and clinical features of DPN are described...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/29165076/pasylation-as-a-powerful-technology-for-improving-the-pharmacokinetic-properties-of-biopharmaceuticals
#9
Sajjad Ahmadpour, Seyed Jalal Hosseinimehr
One of the major challenges of short plasma half-life biopharmaceuticals is to daily high dose administration that leads to economic problems, patient inconvenience and undesirable side effects. Increasing the hydrodynamic volume beyond the pore size of the glomerular basal membrane is a general approach to increase the size of the small biopharmaceuticals with low half-life in blood circulation. PASylation technology is one of these approaches that are designed based on the genetic fusion of biopharmaceutical with a hydrophilic random coil sequence of tri proline (Pro), alanine (Ala), and serine (Ser) amino acids...
November 20, 2017: Current Drug Delivery
https://www.readbyqxmd.com/read/29164787/factors-related-to-duration-of-untreated-psychosis-of-first-episode-schizophrenia-spectrum-disorder
#10
Yong Qiu, Leijun Li, Zhaoyu Gan, Jihui Wang, Liangrong Zheng, Jiaoshi Zhao, Nianhong Guan, Qinling Wei
AIM: Duration of untreated psychosis (DUP) is associated with outcome and functioning. It is expected that scientists will find factors that modulate DUP, but thus far, research on this topic has shown inconsistent results. Furthermore, similar studies in China are insufficient. This study aims to explore social and clinical factors for DUP in South China and to learn the influence that family plays on DUP through their awareness of psychosis. METHODS: Participants included 216 patients with first episode schizophrenia spectrum disorder...
November 22, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29164736/a-technique-to-correct-anterior-posterior-tooth-discrepancy-for-a-maxillary-immediate-complete-denture
#11
Edmond A Bedrossian, Armand Putra, Kwok-Hung Chung
This article describes a chairside technique to correct inappropriate occlusal vertical dimension as well as the inaccurate anterior-posterior tooth set-up of a maxillary immediate complete denture. When fabricating an immediate denture, the inability of a wax-denture trial and the potential for unpredictable complications during surgery, compromised esthetics and function of an immediate complete denture may pose a clinical problem, which needs instant correction. The technique described can provide an alternative method to correct and deliver a definitive immediate complete denture on the day of surgery...
November 21, 2017: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/29164609/who-benefits-from-adolescent-sleep-interventions-moderators-of-treatment-efficacy-in-a-randomized-controlled-trial-of-a-cognitive-behavioral-and-mindfulness-based-group-sleep-intervention-for-at-risk-adolescents
#12
Matthew J Blake, Laura M Blake, Orli Schwartz, Monika Raniti, Joanna M Waloszek, Greg Murray, Julian G Simmons, Elizabeth Landau, Ronald E Dahl, Dana L McMakin, Paul Dudgeon, John Trinder, Nicholas B Allen
BACKGROUND: The aim of this study was to test moderators of therapeutic improvement in an adolescent cognitive-behavioral and mindfulness-based group sleep intervention. Specifically, we examined whether the effects of the program on postintervention sleep outcomes were dependent on participant gender and/or measures of sleep duration, anxiety, depression, and self-efficacy prior to the interventions. METHOD: Secondary analysis of a randomized controlled trial conducted with 123 adolescent participants (female = 59...
November 22, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/29164544/-construction-and-application-of-innovative-education-technology-strategies-in-nursing
#13
Li-Fen Chao, Hsiang-Ping Huang, Lee-Fen Ni, Chia-Lan Tsai, Tsuey-Yuan Huang
The evolution of information and communication technologies has deeply impacted education reform, promoted the development of digital-learning models, and stimulated the development of diverse nursing education strategies in order to better fulfill needs and expand in new directions. The present paper introduces the intelligent-learning resources that are available for basic medical science education, problem-based learning, nursing scenario-based learning, objective structured clinical examinations, and other similar activities in the Department of Nursing at Chang Gung University of Science and Technology...
December 2017: Hu Li za Zhi the Journal of Nursing
https://www.readbyqxmd.com/read/29164514/high-urinary-iodine-thyroid-autoantibodies-and-thyroid-stimulating-hormone-for-papillary-thyroid-cancer-risk
#14
Hengqiang Zhao, Hehe Li, Tao Huang
Thyroid nodules have become a common clinical problem, and the clinical importance of thyroid nodules lies in the determination of thyroid cancer. This study aims to evaluate the risk factors for papillary thyroid cancer (PTC) with regard to urinary iodine concentration (UIC), thyroid-stimulating hormone (TSH), thyroid peroxidase antibody (TPOAb), and thyroglobulin antibody (TGAb) in comparison to thyroid nodular goiter (NG). Among the 2041 patients, 43.8% of which showed more than adequate (UIC 200-299 μg/L) and excessive iodine (UIC ≥ 300...
November 21, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/29164360/risk-of-osteoporosis-after-gastrectomy-in-long-term-gastric-cancer-survivors
#15
Seung Hyun Yoo, Jung Ah Lee, Seo Young Kang, Young Sik Kim, Sung Sunwoo, Beom Soo Kim, Jeong-Hwan Yook
INTRODUCTION: Although early detection and successful gastrectomy have improved the survival of patients with gastric cancer, long-term health problems remain troubling. We evaluated the prevalence of osteoporosis and its risk factors in long-term survivors of gastric cancer after gastrectomy. METHODS: We reviewed the medical records of a tertiary hospital between 2007 and 2014 to identify survivors of gastric cancer who had visited our center at around 5 years after gastrectomy...
November 21, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/29164351/latent-class-symptom-profiles-of-selective-mutism-identification-and-linkage-to-temperamental-and-social-constructs
#16
Rachele Diliberto, Christopher A Kearney
Selective mutism (SM) is a stable, debilitating psychiatric disorder in which a child fails to speak in most public situations. Considerable debate exists as to the typology of this population, with empirically-based studies pointing to possible dimensions of anxiety, oppositionality, and communication problems, among other aspects. Little work has juxtaposed identified symptom profiles with key temperamental and social constructs often implicated in SM. The present study examined a large, diverse, non-clinical, international sample of children aged 6-10 years with SM to empirically identify symptom profiles and to link these profiles to key aspects of temperament (i...
November 21, 2017: Child Psychiatry and Human Development
https://www.readbyqxmd.com/read/29164066/application-of-immunoscore-model-for-the-differentiation-between-active-tuberculosis-and-latent-tuberculosis-infection-as-well-as-monitoring-anti-tuberculosis-therapy
#17
Yu Zhou, Juan Du, Hong-Yan Hou, Yan-Fang Lu, Jing Yu, Li-Yan Mao, Feng Wang, Zi-Yong Sun
Tuberculosis (TB) is a leading global public health problem. To achieve the end TB strategy, non-invasive markers for diagnosis and treatment monitoring of TB disease are urgently needed, especially in high-endemic countries such as China. Interferon-gamma release assays (IGRAs) and tuberculin skin test (TST), frequently used immunological methods for TB detection, are intrinsically unable to discriminate active tuberculosis (ATB) from latent tuberculosis infection (LTBI). Thus, the specificity of these methods in the diagnosis of ATB is dependent upon the local prevalence of LTBI...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/29163947/mechanical-diagnosis-and-therapy-enhances-attitude-toward-self-management-in-people-with-musculoskeletal-disorders-a-preliminary-evidence-with-a-before-after-design
#18
Hiroshi Takasaki
Objectives: Mechanical diagnosis and therapy is one of the most common approaches for the management of low back pain. In mechanical diagnosis and therapy, a great emphasis is placed on patient education so that patients can manage their problems by themselves. However, there has been no evidence that mechanical diagnosis and therapy actually enhances patient's self-management skills. This study aimed to preliminarily investigate whether self-reported skills of self-management for musculoskeletal problems are enhanced through the course of mechanical diagnosis and therapy...
2017: SAGE Open Medicine
https://www.readbyqxmd.com/read/29163869/efficient-identification-of-mental-health-problems-in-refugees-in-germany-the-refugee-health-screener
#19
Elisa Kaltenbach, Eva Härdtner, Katharin Hermenau, Maggie Schauer, Thomas Elbert
Background: A substantial number of refugees present with mental disorders. This appears particularly acute in the currently increasing refugee populations in Europe. Although EU guidelines demand the identification and support of vulnerable individuals such as survivors of trauma, no adequately validated and comprehensive mental health screening instruments for refugees residing in Europe currently exist. Objective: We studied the feasibility, validity, and reliability of the Refugee Health Screener-15 (RHS-15) - a time-efficient and easy-to-implement screening developed by Hollifield et al...
2017: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/29163732/a-comparison-of-the-effects-and-side-effects-of-oral-betahistine-with-injectable-promethazine-in-the-treatment-of-acute-peripheral-vertigo-in-emergency
#20
Hassan Motamed, Meisam Moezzi, Ali Dalir Rooyfard, Kambiz Ahmadi Angali, Zahra Izadi
Background: Vertigo is an illusion of rotation that is caused by the asymmetry of neurological function of the right and left vestibular nuclei. The aim of this study was to compare the efficacy and side effects of oral betahistine with injectable promethazine in treatment of acute peripheral vertigo. Methods: In this double-blind clinical trial study, the patients with acute peripheral vertigo were assigned in the two groups: receiving promethazine intramuscularly at a dose of 25 mg (group A) and receiving 8 mg betahistine tablets (group B) and the severity of their vertigo was evaluated on the visual analog scale (VAS) scoring system...
December 2017: Journal of Clinical Medicine Research
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