keyword
MENU ▼
Read by QxMD icon Read
search

Oxygen Carrier

keyword
https://www.readbyqxmd.com/read/28225712/left-ventricular-function-and-exercise-performance-in-idiopathic-dilated-cardiomyopathy-role-of-tissue-doppler-imaging
#1
Elena Zambon, Annamaria Iorio, Concetta Di Nora, Cosimo Carriere, Elena Abate, Marco Merlo, Giulia Barbati, Andrea Di Lenarda, Bruno Pinamonti, Piergiuseppe Agostoni, Gianfranco Sinagra
BACKGROUND: To examine the relationship between left ventricular (LV) function evaluated at echocardiography and exercise performance in idiopathic dilated cardiomyopathy (IDCM) patients. METHODS AND RESULTS: We enrolled 76 consecutive IDCM patients in sinus rhythm, undergoing cardiopulmonary exercise testing and echocardiography [49 ± 13 years old; LV ejection fraction 31 ± 7%, LV end-diastolic volume 96 ± 31 ml/m; peak oxygen consumption (peak VO2/kg) 18 ± 5...
April 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/28218529/antibacterial-paramagnetic-quinones-from-actinoallomurus
#2
Marianna Iorio, João Cruz, Matteo Simone, Alice Bernasconi, Cristina Brunati, Margherita Sosio, Stefano Donadio, Sonia I Maffioli
Four metabolites, designated paramagnetoquinone A, B, C, and D (1-4), were isolated from three strains belonging to the actinomycete genus Actinoallomurus. Compounds 1 and 2 showed potent antibacterial activity with MIC values lower than 0.015 μg/mL against Gram-positive pathogens, including antibiotic-resistant strains. Since compounds 1 and 2 were NMR-silent due to the presence of an oxygen radical, structure elucidation was achieved through a combination of derivatizations, oxidations, and analysis of (13)C-labeled compounds...
February 20, 2017: Journal of Natural Products
https://www.readbyqxmd.com/read/28218314/implicating-the-contributions-of-surface-and-bulk-states-on-carrier-trapping-and-photocurrent-performance-of-bivo4-photoanodes
#3
B Pattengale, J Huang
Monoclinic-scheelite BiVO4 has been widely studied as a promising oxygen evolution reaction (OER) catalyst in artificial photosynthesis. Though significant progress to improve or augment its catalysis performance has been made, fundamental understanding of its relatively poor performance as a bare material is lacking. In this paper, we report the correlation of the surface structure and trap states with charge separation efficiency and OER performance of bare BiVO4 photoanodes via varying the sample thickness...
February 20, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28213335/transformation-products-of-clindamycin-in-moving-bed-biofilm-reactor-mbbr
#4
Gordon T H Ooi, Monica Escola Casas, Henrik R Andersen, Kai Bester
Clindamycin is widely prescribed for its ability to treat a number of common bacterial infections. Thus, clindamycin enters wastewater via human excretion or disposal of unused medication and widespread detection of pharmaceuticals in rivers proves the insufficiency of conventional wastewater treatment plants in removing clindamycin. Recently, it has been discovered that attached biofilm reactors, e.g., moving bed biofilm reactors (MBBRs) obtain a higher removal of pharmaceuticals than conventional sludge wastewater treatment plants...
February 2, 2017: Water Research
https://www.readbyqxmd.com/read/28212020/a-new-reaction-pathway-induced-by-plasmon-for-selective-benzyl-alcohol-oxidation-on-biocl-possessing-oxygen-vacancies
#5
Hao Li, Feng Qin, Zhiping Yang, Ximin Cui, Jianfang Wang, Lizhi Zhang
Selective organic transformation under mild conditions constitutes a challenge in green chemistry, especially for alcohol oxidation, which typically requires environmentally unfriendly oxidants. Here, we report a new plasmonic catalyst of Au supported on BiOCl containing oxygen vacancies. It photocatalyzes selective benzyl alcohol oxidation with O2 under visible light through synergistic action of plasmonic hot electrons and holes. Oxygen vacancies on BiOCl facilitate the trapping and transfer of plasmonic hot electrons to adsorbed O2, producing •O2(‒) radicals, while plasmonic hot holes remaining on the Au surface mildly oxidize benzyl alcohol to corresponding carbon-centered radicals...
February 17, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28199124/tempo-spatial-activation-of-sequential-quadruple-stimuli-for-high-gene-expression-of-polymeric-gene-nanocomplexes
#6
Hana Cho, Young-Woo Cho, Sun-Woong Kang, Mi-Kyoung Kwak, Kang Moo Huh, You Han Bae, Han Chang Kang
The clinical application of intracellular gene delivery via nanosized carriers is hindered by intracellular multistep barriers that limit high levels of gene expression. To solve these issues, four different intracellular or external stimuli that can efficiently activate a gene carrier, a gene, or a photosensitizer (pheophorbide A [PhA]) were assessed in this study. The designed nanosized polymeric gene complexes were composed of PhA-loaded thiol-degradable polycation (PhA@RPC) and cytomegalovirus (CMV) promoter-equipped pDNA...
February 15, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28195212/loss-of-oxyr-reduces-efficacy-of-oxygen-respiration-in-shewanella-oneidensis
#7
Fen Wan, Miaomiao Shi, Haichun Gao
In many bacteria, OxyR is the major regulator controlling cellular response to H2O2. A common phenotype resulting from OxyR loss is reduced growth rate, but the underlying mechanism is unknown. We demonstrated in Shewanella oneidensis, an important research model for applied and environmental microbes, that the defect is primarily due to an electron shortage to major terminal oxidase cytochrome cbb3. The loss of OxyR leads to enhanced production of electron carriers that compete for electrons against cytochrome cbb3, cytochrome bd in particular...
February 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28194397/a-novel-human-tissue-engineered-3-d-functional-vascularized-cardiac-muscle-construct
#8
Mani T Valarmathi, John W Fuseler, Jeffrey M Davis, Robert L Price
Organ tissue engineering, including cardiovascular tissues, has been an area of intense investigation. The major challenge to these approaches has been the inability to vascularize and perfuse the in vitro engineered tissue constructs. Attempts to provide oxygen and nutrients to the cells contained in the biomaterial constructs have had varying degrees of success. The aim of this current study is to develop a three-dimensional (3-D) model of vascularized cardiac tissue to examine the concurrent temporal and spatial regulation of cardiomyogenesis in the context of postnatal de novo vasculogenesis during stem cell cardiac regeneration...
2017: Frontiers in Cell and Developmental Biology
https://www.readbyqxmd.com/read/28193035/mitochondria-targeted-ratiometric-fluorescent-nanosensor-for-simultaneous-biosensing-and-imaging-of-o2-%C3%A2-and-ph-in-live-cells
#9
Hong Huang, Fangyuan Dong, Yang Tian
Intracellular pH undertakes critical functions in the formation of a proton gradient and electrochemical potential that drives the adenosine triphosphate synthesis. It is also involved in various metabolic processes occurring in mitochondria, such as the generation of reactive oxygen species, calcium regulation, as well as the triggering of cell proliferation and apoptosis. Meanwhile, the aberrant accumulation of O2(•-) within mitochondria is frequently intertwined with mitochondrial dysfunction and disease development...
December 20, 2016: Analytical Chemistry
https://www.readbyqxmd.com/read/28192343/comparison-of-different-two-pathway-models-for-describing-the-combined-effect-of-do-and-nitrite-on-the-nitrous-oxide-production-by-ammonia-oxidizing-bacteria
#10
Longqi Lang, Mathieu Pocquet, Bing-Jie Ni, Zhiguo Yuan, Mathieu Spérandio
The aim of this work is to compare the capability of two recently proposed two-pathway models for predicting nitrous oxide (N2O) production by ammonia-oxidizing bacteria (AOB) for varying ranges of dissolved oxygen (DO) and nitrite. The first model includes the electron carriers whereas the second model is based on direct coupling of electron donors and acceptors. Simulations are confronted to extensive sets of experiments (43 batches) from different studies with three different microbial systems. Despite their different mathematical structures, both models could well and similarly describe the combined effect of DO and nitrite on N2O production rate and emission factor...
February 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28190622/effect-of-carbon-dioxide-on-the-twinkling-artifact-in-ultrasound-imaging-of-kidney-stones-a-pilot-study
#11
Julianna C Simon, Yak-Nam Wang, Bryan W Cunitz, Jeffrey Thiel, Frank Starr, Ziyue Liu, Michael R Bailey
Bone demineralization, dehydration and stasis put astronauts at increased risk of forming kidney stones in space. The color-Doppler ultrasound "twinkling artifact," which highlights kidney stones with color, can make stones readily detectable with ultrasound; however, our previous results suggest twinkling is caused by microbubbles on the stone surface which could be affected by the elevated levels of carbon dioxide found on space vehicles. Four pigs were implanted with kidney stones and imaged with ultrasound while the anesthetic carrier gas oscillated between oxygen and air containing 0...
February 9, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28188676/hemoglobin-based-oxygen-carrier-rescues-double-transplant-patient-from-life-threatening-anemia
#12
M F Gomez, O Aljure, G Ciancio, M Lynn
This is a case of a 46-year-old male, Jehovah's Witness kidney-pancreas transplant recipient found to have early in the postoperative period, splenic vein thrombosis requiring heparin infusion. Two days later, he developed severe symptomatic anemia (Hb < 6 g/dL). Standard medical therapy for bloodless surgical patients with severe anemia was instituted. Nevertheless, the patient's hemoglobin concentration continued to decline to critical levels (2 g/dL). Transfusion of allogeneic blood products was not an option, prompting use of a hemoglobin-based oxygen carrier (HBOC)...
February 11, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28188434/bloodless-reperfusion-with-the-oxygen-carrier-hboc-201-in-acute-myocardial-infarction-a-novel-platform-for-cardioprotective-probes-delivery
#13
Jose M García-Ruiz, Carlos Galán-Arriola, Rodrigo Fernández-Jiménez, Jaume Aguero, Javier Sánchez-González, Ana García-Alvarez, Mario Nuno-Ayala, Gregory P Dubé, Zafiris Zafirelis, Gonzalo J López-Martín, Juan A Bernal, Enrique Lara-Pezzi, Valentín Fuster, Borja Ibáñez
Reperfusion, despite being required for myocardial salvage, is associated with additional injury. We hypothesize that infarct size (IS) will be reduced by a period of bloodless reperfusion with hemoglobin-based oxygen carriers (HBOC) before blood-flow restoration. In the pig model, we first characterized the impact of intracoronary perfusion with a fixed volume (600 ml) of a pre-oxygenated acellular HBOC, HBOC-201, on the healthy myocardium. HBOC-201 was administered through the lumen of the angioplasty balloon (i...
March 2017: Basic Research in Cardiology
https://www.readbyqxmd.com/read/28183818/normalization-of-hemoglobin-based-oxygen-carrier-201-induced-vasoconstriction-roles-of-nitric-oxide-scavenging-and-endothelin
#14
Yannick J Taverne, Daphne P M de Wijs-Meijler, Maaike Te Lintel Hekkert, Paula F Moon-Massat, Greg P Dubé, Dirk Jan Duncker, Daphne Merkus
BACKGROUND: Hemoglobin-based oxygen carrier (HBOC)-201 is a cell-free modified hemoglobin solution potentially facilitating oxygen uptake and delivery in cardiovascular disorders and hemorrhagic shock. Clinical use has been hampered by vasoconstriction in the systemic and pulmonary beds. Therefore we aimed to 1) determine the possibility of counteracting HBOC-201-induced pressor effects with adenosine (ADO), 2) assess the potential roles of nitric oxide (NO) scavenging, reactive oxygen species (ROS) and endothelin (ET) in mediating the observed vasoconstriction and 3) compare these effects in resting and exercising swine...
February 9, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28183632/a-potential-bioactive-wound-dressing-based-on-carboxymethyl-cellulose-zno-impregnated-mcm-41-nanocomposite-hydrogel
#15
Rasul Rakhshaei, Hassan Namazi
Lack of antibacterial activity, deficient water vapor and oxygen permeability, and insufficient mechanical properties are disadvantages of existing wound dressings. Hydrogels could absorb wound exudates due to their strong swelling ratio and give a cooling sensation and a wet environment. To overcome these shortcomings, flexible nanocomposite hydrogel films was prepared through combination of zinc oxide impregnated mesoporous silica (ZnO-MCM-41) as a nano drug carrier with carboxymethyl cellulose (CMC) hydrogel...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28177581/harvesting-hydrogen-gas-from-air-pollutants-with-an-un-biased-gas-phase-photo-electrochemical-cell
#16
Sammy W Verbruggen, Myrthe Van Hal, Tom Bosserez, Jan Rongé, Birger Hauchecorne, Johan A Martens, Silvia Lenaerts
The concept of an all-gas-phase photo-electrochemical cell (PEC) producing hydrogen gas from volatile organic contaminated gas and light is presented. Without applying any external bias, organic contaminants are degraded and hydrogen gas is produced in separate electrode compartments. The system works most efficiently with organic pollutants in inert carrier gas. In the presence of oxygen gas, the cell performs less efficiently but still significant photocurrents are generated, showing the cell can be run on organic contaminated air...
February 8, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28177224/protein-stabilized-gadolinium-oxide-gold-nanoclusters-hybrid-for-multimodal-imaging-and-drug-delivery
#17
Lu Han, Jun-Mei Xia, Xin Hai, Yang Shu, Xu-Wei Chen, Jian-Hua Wang
A protein-stabilized multifunctional theranostic nanoplatform, gadolinium oxide-gold nanoclusters hybrid (Gd2O3-AuNCs), is constructed for multimodal imaging and drug delivery. The Gd2O3-AuNCs nanohybrid is developed by integrating Gd2O3 nanocrystals and gold nanoclusters into bovine serum albumin scaffold as a stabilizer. The nanohybrid exhibits favorable biocompatibility and is capable of enhancing the contrast in magnetic resonance and X-ray computed tomography imaging. Meanwhile, the integrated AuNCs component not only endows the nanohybrid to produce red fluorescence, but also sensitizes the generation of singlet oxygen ((1)O2) upon near-infrared laser stimulation at 808 nm...
February 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28174679/engineering-remotely-triggered-liposomes-to-target-triple-negative-breast-cancer
#18
Alexandra Sneider, Rahul Jadia, Brandon Piel, Derek VanDyke, Christopher Tsiros, Prakash Rai
Triple Negative Breast Cancer (TNBC) continues to present a challenge in the clinic, as there is still no approved targeted therapy. TNBC is the worst sub-type of breast cancer in terms of prognosis and exhibits a deficiency in estrogen, progesterone, and human epidermal growth factor 2 (HER2) receptors. One possible option for the treatment of TNBC is chemotherapy. The issue with many chemotherapy drugs is that their effectiveness is diminished due to poor water solubility, and the method of administration directly or with a co-solvent intravenously can lead to an increase in toxicity...
2017: Oncomedicine
https://www.readbyqxmd.com/read/28165719/design-and-functions-of-semiconducting-fused-polycyclic-furans-for-optoelectronic-applications
#19
Hayato Tsuji, Eiichi Nakamura
The fused polycyclic furan structure is a ubiquitous motif in naturally occurring organic compounds. However, they had been rarely seen in the literature of organic electronic research until very recently, probably because of the lack of stability of simple furans under conditions that the compounds experience in the active layer of the device. Nonetheless, from the viewpoint of molecular structure, furans look to have potential merits as organic semiconductors such as thiophenes, which are more popular in the organic electronic area...
February 6, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28165080/influences-of-the-adsorption-of-different-elements-on-the-electronic-structures-of-a-tin-sulfide-monolayer
#20
Yang Li, Congxin Xia, Juan Du, Wenqi Xiong, Xueping Li, Shuyi Wei
Based on first-principles calculations, we investigated the adsorption energy, structural parameters, and electronic and magnetic properties for the adsorption of different atoms, including light metals, hydrogen, oxygen, and 3D transition metals (TM) adatoms, on a tin sulfide (SnS) monolayer. The results showed that Li- and Al-atom adsorption can effectively induce n-type carriers, whereas O atom adsorption can produce p-type doping in the SnS monolayer. In addition, except for Ni atoms, the other adatoms can induce magnetism in the SnS monolayer...
February 6, 2017: Physical Chemistry Chemical Physics: PCCP
keyword
keyword
70334
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"