Sue Ellen Cox, Joely Kaufman-Janette, Joel L Cohen, Michael Gold, John Joseph, Mark S Nestor, Berthold Rzany, Susan Taylor, Jihao Zhou, Michael Cecerle, Elena Pueraro, Ryan Irvine, Steven Dayan
BACKGROUND: Hyperfunctional glabellar frown lines can transmit facial miscues that adversely affect emotional communication, increase perceptions of age, and diminish self-esteem. OBJECTIVE: To evaluate the efficacy of letibotulinumtoxinA in mitigating the negative psychological impact associated with moderate to severe glabellar lines and to assess subject satisfaction with treatment outcome in the BLESS phase 3 clinical trials. MATERIALS AND METHODS: Baseline and posttreatment assessments were made using validated subject-administered instruments: Modified Skindex-16 Glabellar Line Quality of Life (GL-QoL) Scale, Facial Assessment and Cosmetic Evaluation Questionnaire (FACE-Q) Appraisal of Lines Between Eyebrows Scale, FACE-Q Age Appraisal Visual Analog Scale, and FACE-Q Satisfaction with Outcome Scale...
March 12, 2024: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]