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https://www.readbyqxmd.com/read/28441252/paget-s-disease-of-the-vulva-a-review-of-20-years-experience
#1
Raghava Parashurama, Vivek Nama, Richard Hutson
BACKGROUND: Extramammary Paget's disease is a rare condition, and the vulva is a common site for it to occur. Despite this, there is a paucity of literature on Paget's disease of the vulva (VPD). A Cochrane meta-analysis could not draw any conclusions on interventions in VPD. Our aim was to review our practice and improve further management of VPD in our center. METHODS: We reviewed all the cases presented to Leeds Gynaecological Oncology Centre between 1988 and 2016...
May 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28439910/abo-incompatibility-in-mismatched-unrelated-donor-allogeneic-hematopoietic-cell-transplantation-for-acute-myeloid-leukemia-a-report-from-the-acute-leukemia-working-party-of-the-ebmt
#2
Jonathan Canaani, Bipin N Savani, Myriam Labopin, Mauricette Michallet, Charles Craddock, Gerard Socié, Lisa Volin, Johan A Maertens, Charles Crawley, Didier Blaise, Per T Ljungman, Jan Cornelissen, Nigel Russell, Frédéric Baron, Norbert Gorin, Jordi Esteve, Fabio Ciceri, Christoph Schmid, Sebastian Giebel, Mohamad Mohty, Arnon Nagler
ABO incompatibility is commonly observed in stem cell transplantation and its impact in this setting has been extensively investigated. HLA-mismatched unrelated donors (MMURD) are often used as an alternative stem cell source but are associated with increased transplant related complications. Whether ABO incompatibility affects outcome in MMURD transplantation for acute myeloid leukemia (AML) patients is unknown. We evaluated 1013 AML patients who underwent MMURD transplantation between 2005 and 2014. Engraftment rates were comparable between ABO matched and mismatched patients, as were relapse incidence [34%; 95% confidence interval (CI), 28-39; for ABO matched vs...
April 25, 2017: American Journal of Hematology
https://www.readbyqxmd.com/read/28439849/aortic-valve-replacement-after-coronary-artery-bypass-grafting-with-the-in-situ-right-gastroepiploic-artery-to-the-occluded-right-coronary-artery-using-a-temporary-vein-graft-for-cardioplegia
#3
Yoshifumi Fuke, Toru Yasutsune, Masato Sakamoto
BACKGROUND: The operation of aortic valve replacement (AVR) after CABG is a technically challenging procedure in respect to dissection of living grafts from its surrounding tissue, myocardial protection, and so on, especially that procedure to patients with living in situ functional arterial grafts to occluded native coronary arteries has a special problem in regard to myocardial protection because myocardial blood supply originates from various arteries including the left internal thoracic artery (LITA), the right internal thoracic artery (RITA), and the right gastroepiploic artery (GEA); hence, adequate myocardial protection should be fastidiously considered...
December 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/28434037/open-capsular-and-ligament-reconstruction-with-semitendinosus-hamstring-autograft-successfully-controls-superior-and-posterior-translation-for-type-v-acromioclavicular-joint-dislocation
#4
Raffaele Garofalo, Enrico Ceccarelli, Alessandro Castagna, Vittorio Calvisi, Brody Flanagin, Marco Conti, Sumant G Krishnan
PURPOSE: Appropriate surgical management for type V complete acromioclavicular (AC) joint dislocation remains controversial. The purpose of this paper is to retrospectively report the clinical and radiographic outcomes of an open surgical technique consisting for AC joint ligamentous and capsular reconstruction using autologous hamstring tendon grafts and semi-permanent sutures. METHODS: Between January 2005 and December 2011, 32 consecutive patients with symptomatic type V complete AC joint dislocation underwent surgical treatment using the same technique...
April 22, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28410355/descemetorhexis-without-graft-placement-for-the-treatment-of-fuchs-endothelial-dystrophy-preliminary-results-and-review-of-the-literature
#5
Alfonso Iovieno, Alberto Neri, Anna Maria Soldani, Chantal Adani, Luigi Fontana
PURPOSE: To report our preliminary experience with a central descemetorhexis without graft placement in Fuchs endothelial corneal dystrophy (FECD) and to review the existing literature on the topic. METHODS: A 4-mm central descemetorhexis was performed in 5 patients (4 women, 1 man; mean age: 69.8 ± 8.6 yrs; range: 57-78 yrs) with FECD. All patients had central confluent guttae, undetectable central endothelial cell count, healthy peripheral corneal endothelium, no clinically evident bullous keratopathy, and no ocular comorbidities...
April 13, 2017: Cornea
https://www.readbyqxmd.com/read/28403541/histopathological-evaluation-of-pretransplant-donor-biopsies-in-expanded-criteria-donors-with-high-kidney-donor-profile-index
#6
A Sánchez-Escuredo, A Sagasta, I Revuelta, L M Rodas, D Paredes, M Musquera, F Diekmann, J M Campistol, M Solé, F Oppenheimer
There is no consensus on the allocation of renal transplants from expanded criteria donors (ECD). The Kidney Donor Profile Index (KDPI) is used without the need for pre-transplant donor biopsies (PTDB). We explored whether PTDB based on Remuzzi Score (RS) allows identification of those marginal kidneys in the highest calculated KDPI risk group (>91%) that appropriate for single transplantation. A retrospective study was conducted of 485 consecutive kidneys procured from a single center and transplanted if the RS was <4...
April 12, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28403481/do-flow-and-pulsatility-index-within-the-accepted-ranges-predict-long-term-outcomes-after-coronary-artery-bypass-grafting
#7
Maximiliano De Leon, Roberto Stanham, Gerardo Soca, Victor Dayan
Background Transit-time flow measurement (TTFM) is the gold standard for intraoperative detection of graft failure. Several reports show that TTFM and distal coronary bed quality (DCBQ) may also be useful for midterm detection of graft failure. Nonetheless, there are no data regarding their predictive role on long-term outcomes. Methods Patients with three-vessel disease who underwent isolated coronary artery bypass grafting (CABG) in 2006 and received at least one graft to the left anterior descending artery (LAD) or to the first obtuse marginal (OM1) or posterior descending artery (PDA) were included...
April 12, 2017: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/28400663/tunnel-widening-prevention-with-the-allo-achilles-tendon-graft-in-anterior-cruciate-ligament-reconstruction-surgical-tips-and-short-term-followup
#8
Dong Won Suh, Seung Beom Han, Woo Jin Yeo, Won Hee Lee, Jae Ho Kwon, Bong Soo Kyung
BACKGROUND: Tunnel widening (TW) after anterior cruciate ligament (ACL) reconstruction can be a serious complication, and there is controversy over how to prevent it. This study aimed to suggest surgical approaches to prevent TW using an allo-Achilles tendon graft, and then to evaluate TW after these surgical tips were applied. MATERIALS AND METHODS: Sixty two patients underwent ACL reconstruction with an allo-Achilles tendon graft. Four surgical approaches were used: Making a tibial tunnel by bone impaction, intraarticular reamer application, bone portion application for the femoral tunnel, and an additional bone plug application for the tibial tunnel...
March 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28399024/immediate-reconstruction-for-plantar-melanoma-a-paradigm-shift
#9
Hunter Oliver-Allen, Merisa Piper, Carolyn Vaughn, Hani Sbitany
INTRODUCTION: Plantar melanoma tumors are traditionally treated with wide local excision based on depth of invasion, followed by delayed reconstruction once negative surgical margins are confirmed. However, delayed reconstruction requires care for an open wound, a prolonged treatment course, and the need for an additional surgery. Immediate reconstruction has been shown to be oncologically safe in head and neck melanoma, but little is described in the literature regarding immediate reconstruction in plantar melanoma...
May 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28394527/-laparoscopic-resection-of-the-transplanted-kidney-for-renal-cell-carcinoma-t1n0m0
#10
V I Vtorenko, R N Trushkin, A E Lubennikov, N O Kolesnikov
Laparoscopic resection of the transplanted kidney has been very rarely reported in the literature. On the one hand, this is due to the extremely low incidence of tumors of renal transplants. On the other hand, these patients are usually managed by open surgery due to difficulties in laparoscopic resection because of the scar tissue in the kidney area. Other options, though rarely performed, are cryosurgery and radiofrequency ablation of the tumor. In this article we report our own experience with a patient who underwent laparoscopic resection of renal transplant for renal cell carcinoma T1aN0M0 19 years after kidney transplantation...
April 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/28393781/comparison-of-levosimendan-versus-dobutamine-in-patients-with-moderate-to-severe-left-ventricular-dysfunction-undergoing-off-pump-coronary-artery-bypass-grafting-a-randomized-prospective-study
#11
Ashok Kandasamy, Hariharan Antony Simon, P Murthy, Mahalakshmi Annadurai, Mushkath Mohamed Ali, Gayathri Ramanathan
CONTEXT: Recent upsurge in referral of patients with compromised left ventricular (LV) function for cardiac surgery has led to an increasing use inotropes to achieve improvement of tissue perfusion in the perioperative period. AIMS AND OBJECTIVES: To compare the hemodynamic effects and immediate postoperative outcomes with levosimendan and dobutamine in patients with moderate to severe LV dysfunction undergoing off-pump coronary artery bypass grafting (OPCAB). SETTINGS AND DESIGN: University teaching hospital, randomized control study...
April 2017: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/28392815/gingival-unit-graft-versus-free-gingival-graft-for-treatment-of-gingival-recession-a-randomized-controlled-clinical-trial
#12
Niloofar Jenabian, Mohadese Yazdanpanah Bahabadi, Ali Bijani, Morteza Rahimi Rad
OBJECTIVES: Gingival recession can lead to root exposure and discomfort for patients. There are various techniques for root coverage. The aim of this study was to compare the use of gingival unit graft (palatal graft including the marginal gingiva and papillae) with free gingival graft for treatment of localized gingival recession. MATERIALS AND METHODS: In this randomized controlled clinical trial, 18 bilateral localized recessions of Miller class I and II were treated in nine systemically healthy patients...
June 2016: Journal of Dentistry of Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/28390774/surgeon-leadership-in-the-coding-billing-and-contractual-negotiations-for-fenestrated-endovascular-aortic-aneurysm-repair-increases-medical-center-contribution-margin-and-physician-reimbursement
#13
Francesco Aiello, Jonathan Durgin, Vijaya Daniel, Louis Messina, Danielle Doucet, Jessica Simons, James Jenkins, Andres Schanzer
BACKGROUND: Fenestrated endovascular aneurysm repair (FEVAR) allows endovascular treatment of thoracoabdominal and juxtarenal aneurysms previously outside the indications of use for standard devices. However, because of considerable device costs and increased procedure time, FEVAR is thought to result in financial losses for medical centers and physicians. We hypothesized that surgeon leadership in the coding, billing, and contractual negotiations for FEVAR procedures will increase medical center contribution margin (CM) and physician reimbursement...
April 5, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28389600/intravascular-donor-monocytes-play-a-central-role-in-lung-transplant-ischaemia-reperfusion-injury
#14
Kate Colette Tatham, Kieran Patrick O'Dea, Rosalba Romano, Hannah Elizabeth Donaldson, Kenji Wakabayashi, Brijesh Vipin Patel, Louit Thakuria, Andre Rudiger Simon, Padmini Sarathchandra, Nandor Marczin, Masao Takata
RATIONALE: Primary graft dysfunction in lung transplant recipients derives from the initial, largely leukocyte-dependent, ischaemia-reperfusion injury. Intravascular lung-marginated monocytes have been shown to play key roles in experimental acute lung injury, but their contribution to lung ischaemia-reperfusion injury post transplantation is unknown. OBJECTIVE: To define the role of donor intravascular monocytes in lung transplant-related acute lung injury and primary graft dysfunction...
April 7, 2017: Thorax
https://www.readbyqxmd.com/read/28385945/resection-of-the-ilium-in-patients-with-a-sarcoma-should-the-pelvic-ring-be-reconstructed
#15
M K Laitinen, M C Parry, J I Albergo, V S Umathi, L M Jeys, R J Grimer
AIMS: The aim of the study was to investigate the controversial issue of whether the pelvic ring should be reconstructed following resection of the sarcomas of the ilium. PATIENTS AND METHODS: From our database, we identified 64 patients who underwent excision of a tumour involving the ilium between 1976 and 2015. A total of 35 underwent complete resection, of whom 24 were reconstructed with a non-vascularised fibula graft, and four with extracorporeal irradiation and reimplantation...
April 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28385570/-why-is-it-important-to-differentiate-trichoblastic-carcinomas-ct-from-basal-cell-carcinomas-cbc-about-21-cases
#16
M Thomas, C Bruant-Rodier, F Bodin, B Cribier, M Huther, C Dissaux
Trichoblastic carcinoma is a rare epithelial malignant epithelial tumor, its diagnosis is difficult and the therapeutic management is non-consensual. This retrospective study, carried out between 2009 and 2015, covered 21 cases and analyzed the diagnostic and therapeutic characteristics of trichoblastic carcinomas. Sex ratio is 2. Trichoblastic carcinoma predominated in the face (65% of cases), particularly in perinasal (30% of cases). Its clinical presentation is in 95% of cases as basal cell carcinoma, which is the first clinical diagnosis evoked...
April 3, 2017: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/28383091/a-new-technique-for-the-surgical-treatment-of-atlantoaxial-instability-c1-lateral-mass-and-c2-3-transfacet-screwing
#17
Salim Senturk, Goktug Akyoldas, Onur Yaman, Ali Fahir Ozer
AIM: Atlantoaxial instability is a special entity that may be caused by many disorders such as trauma, tumor, arthritis, congenital malformation and infection. Atlantoaxial fixation is needed to provide stability, prevent neurological deficits and correct deformity. The objective of this study is to introduce an alternative technique for the treatment of atlantoaxial instability in patients who have vertebral artery anomaly, anomalous C2 or osteoporosis. MATERIAL AND METHODS: C1-2-3 fixation was performed in a 50-years-old, male patient with atlantoaxial instability due to os odontoideum...
March 9, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28370489/volumetric-changes-and-peri-implant-health-at-implant-sites-with-or-without-soft-tissue-grafting-in-the-esthetic-zone-a-retrospective-case-control-study-with-a-5-year-follow-up
#18
Stefan P Bienz, Ronald E Jung, Vitor M Sapata, Christoph H F Hämmerle, Jürg Hüsler, Daniel S Thoma
OBJECTIVES: To evaluate the volumetric changes and peri-implant health at implant sites with and without previous soft tissue grafting over a 5-year observation period. MATERIAL AND METHODS: In 18 partially edentulous patients, dental implants were placed in the esthetic zone (15-25) with simultaneous guided bone regeneration, followed by submerged healing. During the healing phase, eight patients (test) received a subepithelial connective tissue graft, whereas 10 patients (control) did not receive any soft tissue augmentation...
March 29, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/28368977/cutaneous-burn-injury-promotes-shifts-in-the-bacterial-microbiome-in-autologous-donor-skin-implications-for-skin-grafting-outcomes
#19
Jennifer K Plichta, Xiang Gao, Huaiying Lin, Qunfeng Dong, Evelyn Toh, David E Nelson, Richard L Gamelli, Elizabeth A Grice, Katherine A Radek
INTRODUCTION: The cutaneous microbiome maintains skin barrier function, regulates inflammation, and stimulates wound healing responses. Burn injury promotes an excessive activation of the cutaneous and systemic immune response directed against commensal and invading pathogens. Skin grafting is the primary method of reconstructing full-thickness burns, and wound infection continues to be a significant complication. METHODS: In this study, the cutaneous bacterial microbiome was evaluated and subsequently compared to patient outcomes...
March 31, 2017: Shock
https://www.readbyqxmd.com/read/28368299/natural-killer-t-cells-in-liver-ischemia-reperfusion-injury
#20
REVIEW
Michael A Zimmerman, Alicia Martin, Jennifer Yee, Jennifer Schiller, Johnny C Hong
Restoration of blood flow to an ischemic organ results in significant tissue injury. In the field of liver transplantation, ischemia-reperfusion injury (IRI) has proven to be a formidable clinical obstacle. In addition to metabolic stress and inflammation, IRI results in profound graft dysfunction and loss. The severity of IRI further limits the ability to expand the donor pool by using partial grafts and marginal organs. As such, the inflammatory response to reperfusion of the liver continues to be an area of intense investigation...
April 1, 2017: Journal of Clinical Medicine
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