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https://www.readbyqxmd.com/read/28438880/testicular-dose-during-prophylaxis-of-heterotopic-ossification-with-radiation-therapy
#1
Waleed F Mourad, John K Ma, Satyaseelan Packianathan, Weisi Yan, Sherif G Shaaban, Edward M Marchan, Lamiaa E Abdallah, Rei He, Paul N Mobit, Chunli Claus Yang, Srinivasan Vijayakumar
AIM: A single-institution, retrospective study was performed to investigate potential techniques to minimize radiation exposure to the testicles during heterotopic ossification (HO) prophylaxis. We report the impact of split-beam technique (SBT) and different photon energies on the total dose of radiation received by the testicles during prophylaxis of HO. MATERIALS AND METHODS: Between 2008 and 2010, we identified 64 patients with traumatic acetabular fractures who underwent surgery followed by radiation therapy (RT) without testicular shielding...
May 2017: In Vivo
https://www.readbyqxmd.com/read/28431283/zika-virus-infection-of-adult-and-fetal-stat2-knock-out-hamsters
#2
Venkatraman Siddharthan, Arnaud J Van Wettere, Rong Li, Jinxin Miao, Zhongde Wang, John D Morrey, Justin G Julander
Zika virus (ZIKV) infection was investigated in adult and fetal STAT2 knock-out (KO) hamsters. Subcutaneous injection of ZIKV of adults resulted in morbidity, mortality, and infection of the uterus, placenta, brain, spinal cord, and testicles, thus providing an opportunity to evaluate congenital ZIKV infection in a second rodent species besides mice. ZIKV-infected cells with morphologies of Sertoli cells and spermatogonia were observed in the testes, which may have implications for sexual transmission and male sterility...
April 18, 2017: Virology
https://www.readbyqxmd.com/read/28427900/molecular-cloning-and-characterization-of-kiss1-in-brandt-s-voles-lasiopodomys-brandtii
#3
Yan Chen, Lan Liu, Zhengguang Li, Dawei Wang, Ning Li, Ying Song, Cong Guo, Xiaohui Liu
Kisspeptin, encoded by kiss1, has been regarded as a major modulator of mammalian puberty and fertility due to its stimulation on GnRH. Brandt's vole is one of the main pest species on the Inner Mongolian steppes for its striking reproductive capacity and kiss1 is a key candidate gene related to reproductive regulatory cascades. In this study, kiss1 cDNA was cloned from the hypothalamus of Brandt's voles and kiss1 mRNA levels were investigated in different tissues, and at different developmental stages, using high-throughput real-time PCR...
April 18, 2017: Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology
https://www.readbyqxmd.com/read/28416925/shear-wave-sonoelastography-findings-of-testicles-in-chronic-kidney-disease-patients-who-undergo-hemodialysis
#4
Azad Hekimoglu, Idil Gunes Tatar, Onur Ergun, Aynur Turan, Mehmet Deniz Aylı, Baki Hekimoglu
OBJECTIVE: Chronic kidney disease (CKD) is known to cause significant deterioration in the function of the testicles and sexual dysfunction in male patients who undergo hemodialysis. The aim of this study was to show the changes in the testicles that occur as a result of hypogonadism secondary to CKD and to analyze the elasticity of the parenchyma by shear wave sonoelastography. MATERIALS AND METHODS: In our study we included 28 male patients who undergo dialysis three times per week and 25 healthy volunteers...
February 2017: Eurasian Journal of Medicine
https://www.readbyqxmd.com/read/28414684/who-shot-the-cannonballs-extensive-lung-metastases-in-a-39-year-old-man
#5
D Sommerhalder, J Blondin
CASE: A 39 year-old man presented to the emergency department complaining of a cough of 2 months in duration. He also complained of weight loss of 20 pounds in two months and night sweats over the same period. An x-ray of the chest was performed and revealed innumerable lung nodules and masses. Computed tomography of the chest and abdomen were subsequently performed which confirmed the masses, but imaging did not reveal an obvious primary source. A testicular exam was performed but no obvious abnormalities were noted...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28404209/investigation-of-toxoplasma-gondii-in-semen-testicle-and-epididymis-tissues-of-primo-infected-cats-felis-catus
#6
Weslen Fabricio Pires Teixeira, Maria Eduarda Gonçalves Tozato, Julia Cestari Pierucci, Giovana Pavão Vital, André Cayeiro Cruz, Welber Daniel Zanetti Lopes, Marina Suzuki Cursino, Samea Fernandes Joaquim, Vando Edésio Soares, Helio Langoni, Kátia Denise Saraiva Bresciani, Alvimar José da Costa
This study aimed to investigate the presence of Toxoplasma gondii in semen, testicle and epididymis tissues of cats experimentally infected by this coccidium. A total of 12 male felines without a definite breed that were of reproductive age and serologically negative for T. gondii were selected and distributed to the following three experimental groups: GI, inoculated with 600 tissue cysts of the P strain of T. gondii (isolate III); GII, inoculated with 2×10(5) tachyzoites of the RH strain (isolate I); and GIII, not inoculated (control group)...
April 3, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28402060/evaluation-of-different-fragment-sizes-and-cryoprotectants-for-cryopreservation-of-feline-testicular-tissues
#7
B I Macente, G H Toniollo, M Apparicio, Cfm Mansano, H E Thomé, C L Canella, Meg Tozato, R R Gutierrez
This study aimed to evaluate tissue damage of feline testicles sectioned in two different sizes (0.3 or 0.5 cm(3) ) and submitted to different cryoprotectants (propanediol or glycerol). Testicles obtained from 12 domestic cats were sectioned in 0.3 and 0.5 cm(3) sized pieces and immediately evaluated by TBARS and semi-quantitatively by histomorphology. The remaining fragments were placed in cryotubes with 1 ml Egg yolk Tris Equex STM extender containing 3% glycerol or 3% propanediol and cryopreserved by fast-freezing technique...
April 2017: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/28400459/investigating-the-relationship-between-precocious-puberty-and-obesity-a-cross-sectional-study-in-shanghai-china
#8
Chang Chen, Yunting Zhang, Wanqi Sun, Yao Chen, Yanrui Jiang, Yuanjin Song, Qinmin Lin, Lixia Zhu, Qi Zhu, Xiumin Wang, Shijian Liu, Fan Jiang
OBJECTIVES: Obesity is reported to be closely relevant to early sexual development but the relationship between sexual precocity and obesity or central obesity is still inconsistent, especially in boys. We aimed to investigate the relationship between precocious puberty and obesity as well as central obesity. DESIGN: A large population-based cross-sectional study using multistage, stratified cluster random sampling. SETTING: Data from the Shanghai Children's Health, Education and Lifestyle Evaluation (SCHEDULE) study in June 2014...
April 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28395666/hydroxytyrosol-prevents-reduction-in-liver-activity-of-%C3%AE-5-and-%C3%AE-6-desaturases-oxidative-stress-and-depletion-in-long-chain-polyunsaturated-fatty-acid-content-in-different-tissues-of-high-fat-diet-fed-mice
#9
Rodrigo Valenzuela, Francisca Echeverria, Macarena Ortiz, Miguel Ángel Rincón-Cervera, Alejandra Espinosa, María Catalina Hernandez-Rodas, Paola Illesca, Alfonso Valenzuela, Luis A Videla
BACKGROUND: Eicosapentaenoic acid (EPA, C20:5n-3), docosahexaenoic acid (DHA, C22:6n-3) and arachidonic acid (AA, C20:4n-6) are long-chain polyunsaturated fatty acids (LCPUFAs) with relevant roles in the organism. EPA and DHA are synthesized from the precursor alpha-linolenic acid (ALA, C18:3n-3), whereas AA is produced from linoleic acid (LA, C18:2n-6) through the action of Δ5 and Δ6-desaturases. High-fat diet (HFD) decreases the activity of both desaturases and LCPUFA accretion in liver and other tissues...
April 11, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28386495/bilateral-sertoli-cell-tumors-in-a-patient-with-androgen-insensitivity-syndrome
#10
Roberta Fonseca de Souza, Janaina Pereira da Silva, Bruno Vieira Balla, Rodrigo Neves Ferreira, Antônio Chambô Filho
Androgen insensitivity syndrome is the most common cause of male pseudohermaphroditism and the third most common cause of primary amenorrhea. This genetic alteration is a consequence of inherited defects on the X chromosome causing total or partial damage to the intrauterine virilization process due to functional abnormalities in the androgen receptors. The present report describes a 22-year-old patient with a female phenotype and a 46, XY karyotype, presenting with bilateral inguinal tumors. The tumors were surgically removed at the Santa Casa de Misericórdia Hospital in Vitória, Espírito Santo, Brazil...
2017: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28385395/cytoplasmic-droplet-acting-as-a-mitochondrial-modulator-during-sperm-maturation-in-dogs
#11
D S R Angrimani, J D A Losano, C F Lucio, G A L Veiga, F C Landim, M Nichi, C I Vannucchi
Motility acquisition during sperm maturation and passage through the epididymis is closely related to mitochondrial function and appears to occur in parallel with cytoplasmic droplet (CD) migration. However, such mechanism remains unclear in dogs. Thus, the aim of this study was to characterize the influence of sperm CD in the mitochondrial functionality during epididymal sperm maturation in dogs. Twenty-one adult dogs were submitted to elective bilateral orchiectomy. Testicles were stored for 18-24h at 5°C and epididymal sperm samples were then collected from different segments of the epididymis (caput, corpus and cauda)...
March 30, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/28367922/effects-of-dietary-fish-oil-and-apple-polyphenol-on-the-concentration-serum-lipids-and-excretion-of-fecal-bile-acids-in-rats
#12
Yasue Hosoyamada, Masako Yamada
We studied the effects of fish oil and apple polyphenol combined with a high cholesterol diet in rats, and assessed serum and liver lipids concentrations, serum oxidative stress and fecal bile acid excretion. Young male rats were fed a diet containing the control (Control), apple polyphenol (AP), fish oil (FO) or fish oil+apple polyphenol (FO+AP) for 4 wk. The control diet contained a lard component. Posterior abdominal wall fat and testicle peripheral fat weights decreased in the FO+AP group compared to the AP group...
2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/28364806/lufenuron-impact-upon-anthonomus-grandis-boheman-coleoptera-curculionidae-midgut-and-its-reflection-in-gametogenesis
#13
Hilton Nobre Costa, Franklin Magliano da Cunha, Glaucilane Santos Cruz, Carolline Guimarães D'assunção, Guilherme Gomes Rolim, Maria Edna Gomes Barros, Mariana Oliveira Breda, Alvaro Aguiar Coelho Teixeira, Valéria Wanderley Teixeira
The insecticide Match® (lufenuron), one of the main insect growth regulators used in pest control, has been presented as a viable alternative against the boll weevil, Anthonomus grandis (Coleoptera: Curculionidae), by inhibiting chitin synthesis. Thus, this study aimed to examine whether Match® interferes in the synthesis of the peritrophic matrix, leading to changes in the midgut epithelium, resulting in nutritional deficiency and reflecting, thereby, in the gametogenesis process of A. grandis. Floral cotton buds were immersed in the insecticide solution (800μL of Match®+200mL of distilled water) and offered to the adult insects...
April 2017: Pesticide Biochemistry and Physiology
https://www.readbyqxmd.com/read/28346969/the-comparison-of-laparoscopic-and-microsurgical-varicocoelectomy-in-infertile-men-with-varicocoele-on-paternity-rate-12%C3%A2-months-after-surgery-a-prospective-randomized-controlled-trial
#14
RANDOMIZED CONTROLLED TRIAL
P Bryniarski, P Taborowski, P Rajwa, Z Kaletka, M Życzkowski, A Paradysz
The best surgical approach for varicocoelectomy is still unknown, however more and more physicians favour subinguinal microsurgery. The aim of this study was to find whether microsurgical approach is superior to laparoscopic varicocoelectomy in terms of pregnancy rate, fertility potential, endocrinological function of the testis, erectile dysfunction and testicle volume increase. It was a prospective, non-masked, parallel-group randomized controlled trial with one to one allocation. It was conducted at authors' institution and designed as per protocol study...
May 2017: Andrology
https://www.readbyqxmd.com/read/28340890/reproductive-disorders-in-pet-rodents
#15
REVIEW
Jaume Martorell
Reproduction diseases are common presentations in small rodents. Some can be presented to the clinician as an emergency where a fast and effective treatment is required. This article presents an overview of reproductive disorders in these species. Diseases affecting the ovary, uterus, testicles, and mammary gland are developed in rats, mice, hamsters, and gerbils: inflammatory, infectious, and neoplasia. Clinical signs, diagnosis, and treatment information are included. Some specific indications about the surgical reproduction procedures are described...
May 2017: Veterinary Clinics of North America. Exotic Animal Practice
https://www.readbyqxmd.com/read/28337635/measurement-of-bovine-body-and-scrotal-temperature-using-implanted-temperature-sensitive-radio-transmitters-data-loggers-and-infrared-thermography
#16
A L Wallage, J B Gaughan, A T Lisle, L Beard, C W Collins, S D Johnston
Synchronous and continuous measurement of body (BT) and scrotal temperature (ST) without adverse welfare or behavioural interference is essential for understanding thermoregulation of the bull testis. This study compared three technologies for their efficacy for long-term measurement of the relationship between BT and ST by means of (1) temperature sensitive radio transmitters (RT), (2) data loggers (DL) and (3) infrared imaging (IRI). After an initial pilot study on two bulls to establish a surgical protocol, RTs and DLs were implanted into the flank and mid-scrotum of six Wagyu bulls for between 29 and 49 days...
March 23, 2017: International Journal of Biometeorology
https://www.readbyqxmd.com/read/28336287/a-unique-case-of-pentaorchidism
#17
Amanda Myers, Bradley Morganstern, Ronnie Fine
Polyorchidism is a rare congenital anomaly with less than 200 case reports in literature. Triorchidism - three testicles - is the most common presentation. We present an unusual case of a patient who was diagnosed with five testicles by magnetic resonance imaging. To the best of our knowledge, this rare presentation has not previously been reported in the medical literature.
March 20, 2017: Urology
https://www.readbyqxmd.com/read/28331810/juvenile-granulosa-cell-tumor-of-the-testicle-report-of-a-neonatal-case-with-positive-alpha-fetoprotein-immunohistochemical-staining
#18
Melissa Dundas, Mark Horowitz, Richard Sidlow
We report on a case of juvenile granulosa cell tumor of the testicle in a neonate, a rare testicular tumor in children. No genital ambiguity, anatomic abnormalities, nor sex chromosome aneuploidy was noted in this patient. In our case, despite positive staining for alpha-fetoprotein which is most consistent with yolk sac tumors, all clinical, gross anatomic, histologic, and other immunohistologic characteristics of the tumor remained consistent with the diagnosis of juvenile granulosa cell tumor. The alpha-fetoprotein positivity of the tumor remains unexplained...
May 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28330548/-polyorchidism-is-a-rare-cause-of-a-scrotal-mass
#19
Grete Padkær, Bassam Hamid Mahdi, Poul Erik Andersen, Lars Lund
In this case report we present a 14-year-old boy with two testicles in the right hemiscrotum - a case of polyorchidism. He did not have surgery for his condition, and his condition was followed according to the guidelines. In a study, 6.4% of cases with polyorchidism were found to contain neoplasms of which the most were malignant. If the supernumerary testicle is not contributing to the spermatogenesis, it is therefore recommended to remove the testicle. Otherwise, recommendations are a yearly follow-up by Doppler ultrasound, including a physical examination to discover development of cancer...
March 20, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28322096/cdx2-immunostaining-in-primary-and-metastatic-germ-cell-tumours-of-the-testis
#20
Fatma Oz Atalay, Berna Aytac Vuruskan, Hakan Vuruskan
Objective To evaluate the immunohistochemical staining pattern of caudal type homeobox 2 (CDX2) protein in germ cell tumours (GCTs) of the testis. Methods This study reassessed archival tissue samples collected from patients diagnosed with primary and metastatic testicular GCTs for CDX2 immunoreactivity using standard immunohistochemical techniques. Positive nuclear immunostaining was evaluated with regard to both the staining intensity and the extent of the staining. Results Tissue sections from primary and metastatic testicular GCTs ( n = 104), germ cell neoplasia in situ (GCNis) ( n = 5) and benign testicles ( n = 15) were analysed...
December 2016: Journal of International Medical Research
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