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https://www.readbyqxmd.com/read/29353141/vitrification-of-testicular-tissue-from-prepubertal-cats-in-cryotubes-using-different-cryoprotectant-associations
#1
David Baruc Cruvinel Lima, Ticiana Franco Pereira da Silva, Annice Aquino-Cortez, Johanna Leiva-Revilla, Lúcia Daniel Machado da Silva
Protocols for the cryopreservation of testicular tissue are not yet established. In cats, few studies have been conducted on testicular vitrification using different cryoprotectant associations (CPAs). Thus, the objective of this study was to compare the effect of different CPAs on the vitrification of testicular tissue from prepubertal cats in cryotubes. We used 10 pairs of testicles, with each pair divided into 8 fragments that were distributed into different experimental groups. Two of these fragments were allocated into the control group (CG) and the other six were distributed according to the CPAs to be tested (dimethyl sulfoxide (DMSO)/glycerol (GLY), ethylene glycol (EG)/GLY, or DMSO/EG)...
January 5, 2018: Theriogenology
https://www.readbyqxmd.com/read/29342466/deep-vein-thrombosis-a-rare-cause-of-acute-testicular-pain-case-report-literature-review
#2
Adrián Amador Robayna, Jonathan Rodríguez Talavera, Begoña Ballesta Martínez, Javier Falcón Barroso, Almudena Carrión Valencia, Nuria Orribo Morales, Melania Santacruz Pérez, Jesús Monllor Gisbert
INTRODUCTION: Thrombosis is defined as the formation of a clot in a blood vessel that obstructs the flow of blood to the peripheral tissues. The incidence of thromboembolic disease ranges from 0.7 to 1.2% within urology. CASE REPORT: A 40-year-old warehouse worker male presented to the emergency department with worsening of a month's lasting scrotal pain. Physical examination showed the presence of an enlarged and painful left testicle with no other findings. Right testicle, penis and abdominal examination showed no abnormalities whatsoever...
January 17, 2018: Urologia Internationalis
https://www.readbyqxmd.com/read/29331980/dmc1-mutation-that-causes-human-non-obstructive-azoospermia-and-premature-ovarian-insufficiency-identified-by-whole-exome-sequencing
#3
Wen-Bin He, Chao-Feng Tu, Qiang Liu, Lan-Lan Meng, Shi-Min Yuan, Ai-Xiang Luo, Fu-Sheng He, Juan Shen, Wen Li, Juan Du, Chang-Gao Zhong, Guang-Xiu Lu, Ge Lin, Li-Qing Fan, Yue-Qiu Tan
BACKGROUND: The genetic causes of the majority of male and female infertility caused by human non-obstructive azoospermia (NOA) and premature ovarian insufficiency (POI) with meiotic arrest are unknown. OBJECTIVE: To identify the genetic cause of NOA and POI in two affected members from a consanguineous Chinese family. METHODS: We performed whole-exome sequencing of DNA from both affected patients. The identified candidate causative gene was further verified by Sanger sequencing for pedigree analysis in this family...
January 13, 2018: Journal of Medical Genetics
https://www.readbyqxmd.com/read/29325584/adenomatoid-tumor-of-the-testis-mimicking-malignant-testicular-cancer-on-multiparametric-ultrasound
#4
Renate Pichler, Gennadi Tulchiner, Fabian Steinkohl, Afschin Soleiman, Wolfgang Horninger, Isabel Maria Heidegger, Friedrich Aigner
BACKGROUND: Adenomatoid tumor is one of the most common histological subtypes of paratesticular cancer arising from the epididymis. In very rare cases, these tumors appear as intratesticular lesions originating in the tunica albuginea, representing a diagnostic challenge. CASE PRESENTATION: We present a case of a 51-year-old man with a small (0.9 cm) hyperechoic lesion of the left testicle mimicking testicular cancer on multiparametric ultrasound. The lesion was localized in the peripheral zone, confirming vascularization and increased stiffness on contrast-enhanced ultrasound and real-time elastography...
January 11, 2018: European Journal of Medical Research
https://www.readbyqxmd.com/read/29315760/protective-influence-of-rosiglitazone-against-testicular-ischaemia-reperfusion-injury-in-rats
#5
N Zheng, H Shao, D Wu, D Shen, X Lin
Testicular torsion is a urology urgent disease which causes testicular injury and potential sterility. In this study, we explored the protective influence of rosiglitazone on testicular ischaemia-reperfusion damage. There were 28 male Sprague Dawley rats in total, which were assigned randomly to four groups. Group A was blank control one; group B was testicular injury one; group C was rosiglitazone one; group D was rosiglitazone antagonist one. The testicles were counter-rotated after 2 hr and then underwent orchiectomy 24 hr later...
January 9, 2018: Andrologia
https://www.readbyqxmd.com/read/29305943/pediatric-testicular-hemangioma-in-a-10-year-old-a-rare-entity-that-may-mimic-malignancy-with-appraisal-of-the-literature
#6
Sarah B Hugar, Brian Kadow, Amy Davis, Sarangarajan Ranganathan, Miguel Reyes-Múgica, Francis X Schneck, Jennifer Picarsic
Capillary hemangioma is a rare benign lesion in the testicle, particularly in pediatrics. It can mimic malignancy, leading to radical orchiectomy. We present a case of a testicular hemangioma in a child, and review the literature on testicular hemangiomas in this age group. A hypervascular testicular lesion without elevated tumor markers may warrant intraoperative biopsy to direct surgical management, which may include testis-sparing surgery if amenable.
January 3, 2018: Urology
https://www.readbyqxmd.com/read/29303051/a-novel-function-of-geranylgeraniol-in-regulating-testosterone-production
#7
Hsin-Jung Ho, Hitoshi Shirakawa, Puspo E Giriwono, Asagi Ito, Michio Komai
Isoprenoids play widely differing roles in various physiological processes in animals and plants. Geranylgeraniol (GGOH) is an isoprenoid found in plants, and is an important metabolic derivative in the isoprenoid/cholesterol synthesis pathway. Earlier studies focused on GGOH's ability to improve the side effects of bisphosphonate therapy by regulating the mevalonate pathway. More recently, the mevalonate pathway-independent effects of GGOH have been described, including anti-inflammatory, anti-tumorigenic, and neuroprotective activities...
January 5, 2018: Bioscience, Biotechnology, and Biochemistry
https://www.readbyqxmd.com/read/29300118/genome-wide-linkage-analysis-identifies-loci-for-testicle-and-ovary-traits-in-chickens
#8
Yanfa Sun, Ranran Liu, Guiping Zhao, Maiqing Zheng, Peng Li, Li Liu, Jie Wen
Development of testes or ovaries is critical to chicken breeders. Understanding the genetic mechanisms influencing the development of the testes and ovaries could enhance selection efforts which target reproductive traits. The linkage analysis was conducted within an F2 population derived from Beijing-You chickens and a commercial broiler line. The results have identified one quantitative trait loci (QTL, designated T1) for bilateral testicular weight (TW) and the percentage of TW to carcass weight, and five QTLs (designated O1-O5) for ovary weight (follicle-free, OW) and the percentage of OW to carcass weight...
January 4, 2018: Animal Biotechnology
https://www.readbyqxmd.com/read/29288977/maternal-nutritional-restriction-during-late-gestation-impairs-development-of-the-reproductive-organs-in-both-male-and-female-lambs
#9
F Hoffman, E Boretto, S Vitale, V Gonzalez, G Vidal, M F Pardo, M F Flores, F Garcia, G Bagnis, O C M Queiroz, M B Rabaglino
Maternal nutritional restrictions during late gestation could lead to fetal hypoglycemia. Glucose levels in the fetal sheep regulate circulating insulin-like growth factor 1 (IGF1) levels, which stimulate cell proliferation and differentiation of reproductive organs after binding to its own receptor or estrogen receptors. The objective of this study was to determine the effects of subnutrition of ewes during the last trimester of gestation on the serum glucose/IGF1 levels and development of reproductive organs in their lambs...
December 15, 2017: Theriogenology
https://www.readbyqxmd.com/read/29288976/maternal-parity-affects-placental-development-growth-and-metabolism-of-foals-until-1-year-and-a-half
#10
M Robles, C Dubois, C Gautier, M Dahirel, I Guenon, H Bouraima-Lelong, C Viguié, L Wimel, A Couturier-Tarrade, P Chavatte-Palmer
Primiparous mares are known to produce smaller foals than multiparous mares. This difference seems to be partly explained by the reduced exchange surface and volume of the placental villi in primiparous compared to multiparous placentas. The effect of maternal parity on foals' post-natal growth, metabolism and sexual maturation, however, has been given little consideration. The objectives of this work were to analyse placental biometry and structure at term, growth of foals and yearlings, their metabolism and testicular maturation at one year of age...
December 21, 2017: Theriogenology
https://www.readbyqxmd.com/read/29279691/recurrent-masses-after-testicular-cancer-growing-teratoma-syndrome-a-case-report-and-review-of-the-literature
#11
Fanny Priod, Francis Lorge, Marcelo Di Gregorio, Michaël V Dupont, Marie-Cécile Nollevaux, Laurence Faugeras, Georges Lawson, Philippe Eucher, Lionel D'Hondt
Background: Growing teratoma syndrome is a rare syndrome that affects patients with nonseminomatous germ-cell tumors (NSGCTs). It is characterized by recurrent growing masses that appear during or after chemotherapy in the presence of normal levels of tumor markers. Histological examination is the only way to confirm the diagnosis. Case Presentation: We present the case of a 36-year-old man who developed recurrent masses after curative treatment for NSGCT of the testicle...
September 2017: Case Reports in Oncology
https://www.readbyqxmd.com/read/29276802/comparison-of-tissue-stiffness-using-shear-wave-elastography-in-men-with-normal-testicular-tissue-testicular-microlithiasis-and-testicular-cancer
#12
Malene Roland Pedersen, Henrik Møller, Palle Jørn Sloth Osther, Peter Vedsted, René Holst, Søren Rafael Rafaelsen
Objectives: To compare elastography measurements in men with normal testicular tissue, testicular microlithiasis and testicular cancer. Methods: A total of 248 consecutive patients were included. All men provided written informed consent. Testicular stiffness was assessed using shear wave elastography (SWE). Three SWE velocity measurements were assessed in each testicle. The patients were divided into three groups; men with normal testicular tissue (n=130), men with testicular microlithiasis (n=99) and men with testicular cancer (n=19)...
September 2017: Ultrasound International Open
https://www.readbyqxmd.com/read/29259856/the-expression-profile-of-ifitm-family-gene-in-rats
#13
Yanqin Lu, Qingli Zuo, Yao Zhang, Yanzhou Wang, Tianyou Li, Jinxiang Han
The interferon-inducible transmembrane proteins (IFITMs) are a family of small transmembrane proteins belonging to the interferon (IFN)-stimulated gene (ISG) superfamily and strongly induced by IFNs. In this paper, we studied the expression profile of IFITMs in 32 organ tissues. The IFITM mRNA expression profile showed that IFITM1, IFITM2 and IFITM3 were expressed in each tissue, especially, in spermatophore, spermaduct, testicle and epididymis. The expression of IFITM1, IFITM2 and IFITM3 showed a trend from high to low...
November 2017: Intractable & Rare Diseases Research
https://www.readbyqxmd.com/read/29242732/usefulness-of-tc-99m-pertechnetate-spect-ct-in-the-diagnosis-of-testicular-infarction-after-inguinal-herniorrhaphy
#14
Myoung Hyoun Kim, Chang Guhn Kim, Soon-Ah Park, Dae-Weung Kim
A 77-year-old male underwent open repair for a right indirect inguinal hernia and complained of right scrotal pain on the third postoperative day. Color Doppler imaging revealed decreased blood flow with heterogeneous hypoechogenicity in the right testis. A Tc-99m pertechnetate testicular scan showed diffuse hyperemia and increased uptake in the right scrotum. Additional SPECT/CT revealed a photon defect in the right testicle with increased uptake in the peri-testicular area. A subsequent operation revealed a large hematoma in the right spermatic cord and consequent right testicular infarction, and right orchiectomy was performed...
December 2017: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29234092/advantage-of-early-orchiopexy-for-undescended-testis-analysis-of-testicular-growth-percentage-ratio-in-patients-with-unilateral-undescended-testicle
#15
Chi-Shin Tseng, I-Ni Chiang, Chung-Hung Hong, Yu-Chuan Lu, Jian-Hua Hong, Hong-Chiang Chang, Kuo-How Huang, Yeong-Shiau Pu
This study reports the experience of our tertiary referral center and proposes a new indicator, the growth percentage ratio (GPR), for determining the optimal timing of surgical intervention. A retrospective review of boys who underwent orchiopexy for undescended testis from 2001 to 2013 was conducted. We analyzed testicular volumes in different age groups using the UDT to normally descended testis ratio and testicular GPR. A total of 134 boys with unilateral undescended testicle underwent regular ultrasonography follow-up examinations for more than a mean of 3...
December 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29230496/testicle-sparing-surgery-versus-radical-orchiectomy-in-the-management-of-leydig-cell-tumors-results-from-a-multicenter-study
#16
Florian Laclergerie, Guillaume Mouillet, Alexandre Frontczak, Loïc Balssa, Pascal Eschwege, Christian Saussine, Stéphane Larré, Luc Cormier, Antoine Thiery Vuillemin, François Kleinclauss
OBJECTIVE: To compare the oncological outcomes of testicle-sparing surgery (TSS) and radical orchiectomy (RO) in patients with Leydig cell tumor (LCT) of the testis. PATIENTS AND METHODS: A multicenter retrospective clinical study was conducted in 12 centers in France. All the patients with histologically proven LCT were included and analyzed according to treatment (organ-sparing surgery or radical orchiectomy). Patients underwent preoperative clinical, biological and imaging assessment...
December 11, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/29209550/rare-case-of-large-bowel-injury-due-to-direct-blunt-trauma-to-a-preexisting-femoral-hernia
#17
C Tinner, M Odermatt, P Villiger
We report a case of an 85-year-old man with a known asymptomatic left femoral hernia who was admitted to the emergency ward a few hours after falling from a bicycle and suffering from blunt trauma of the handlebar to the left inguinal region. The clinical findings and a computed tomography (CT) scan detecting free air in the femoral hernia sac suggested bowel perforation. Emergency laparotomy 6 hours after the incident confirmed a tear of the sigmoid colon accompanied by free blood and faeces in the left inguinal region of the abdomen...
2017: Case Reports in Surgery
https://www.readbyqxmd.com/read/29207773/testicular-and-epididymal-metastasis-from-prostate-carcinoma-a-rare-manifestation-of-common-disease
#18
Jayesh Mittal, L N Dorairajan, R Manikandan, Bhawanan A Bade, Amit Mishra
Carcinoma prostate secondary metastasis to testicle and epididymis is rare. We report a case of metastatic carcinoma prostate in which testicular and epididymal metastasis were diagnosed incidentally in bilateral orchiectomy specimen. Testicular and para testicular structure should be properly evaluated for accurate staging of carcinoma prostate. Epididymis should always be included in bilateral orchidectomy specimen.
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29205163/extramedullary-plasmacytoma-of-the-testicle
#19
Diego M Carrion, Mario Álvarez-Maestro, Juan Gómez Rivas, Pilar González-Peramato, Jesús Cisneros Ledo
OBJECTIVE: We present the case of a patient diagnosed with a testicular extramedullary plasmacytoma (EMP), and perform a brief review of the literature of this pathology. METHODS: A 64 year-old male patient, with history of multiple myeloma successfully treated three years before, presented with left testicular swelling. Initial work-up was compatible with a testicular tumor and radical inguinal orchiectomy was performed. RESULTS: Histologic examination of the testis revealed extensive intertubular infiltration by CD138 and CD56 atypical plasma cells, with diffuse staining for IgA, compatible with EMP...
December 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/29201487/primary-malignancy-in-a-supernumerary-testicle-presenting-as-a-large-pelvic-mass
#20
Justin Noroozian, Daniel Farishta, Daniel Ballow, Joseph Sonstein, Eduardo Orihuela, Eduardo Eyzaguirre
Supernumerary testis, also known as polyorchidism, is a condition characterized by the presence of more than two testes. Another condition of the testes is seminoma, a common cause of testicular germ cell tumor. A 35-year-old male was transferred to our hospital with a diagnosis of abdominal mass causing abdominal pain. On physical exam, he had a palpable undescended left testicle in the left inguinal canal, which was determined to be seminoma. The mass was surgically removed, and the patient underwent chemotherapy...
2017: Case Reports in Urology
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