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https://www.readbyqxmd.com/read/27921092/testicular-microlithiasis-patient-compliance-in-a-two-year-follow-up-program
#1
M R Pedersen, P J S Osther, F B Soerensen, S R Rafaelsen
Introduction: We present a retrospective 2-year follow-up cohort of 103 men with testicular microlithiasis (TML) and discuss patient compliance and the value of surveillance. Methods: A retrospective analysis of patients examined with scrotal ultrasonography (US) in the period from 2008 through 2010 was performed. A total of 103 men with TML were diagnosed and offered US follow-up every 6 months for 2 years. They were retrospectively analyzed regarding demographics and follow-up details, including the development of any kind of malignancy until March 2015, using the Danish Electronic Pathology Registry...
November 2016: Ultrasound International Open
https://www.readbyqxmd.com/read/27920989/dartos-fascia-interposition-flap-for-penetrating-cavernosal-and-urethral-trauma
#2
Hailiu Yang, Robert D Brown, John Chovanes, Allen D Seftel
We present an unusual case of a single gunshot to the genitalia in which the bullet trajectory injured the urethra, corpus cavernosum, and both testicles. All injuries were successfully repaired during initial exploration. Our report serves as a reminder to clinicians to have a high index of suspicion in this circumstance and consider immediate exploration of all the injured areas. We also demonstrate the use of a dartos fascia interposition flap to cover and separate the concomitant urethral and corporal sutures lines...
January 2017: Urology Case Reports
https://www.readbyqxmd.com/read/27909618/clinico-pathological-outcomes-of-post-primary-and-salvage-chemotherapy-retroperitoneal-lymph-node-dissection-for-mixed-germ-cell-tumors-king-hussein-cancer-center-experience
#3
Kholoud Alqasem, Ibrahim Abukhiran, Judy Jasser, Tamer Bisharat, Riyad T Ellati, Jakub Khzouz, Ibrahim Al-Saidi, Ali Al-Daghamin
OBJECTIVE: We sought to characterize clinical and pathologic outcomes of advanced mixed germ cell tumors after retroperitoneal lymph node dissection for post-chemotherapy residual masses. MATERIAL AND METHODS: Between January 2006 and November 2015, 56 patients underwent retroperitoneal lymph node dissection (RPLND) for residual masses of greater than 1 cm after receiving either primary chemotherapy or salvage chemotherapy. Retrospective review of the patients' characteristics, clinical, pathological, and treatment outcomes were performed after institutional review board (IRB) and ethics committee approval...
December 2016: Turkish Journal of Urology
https://www.readbyqxmd.com/read/27908670/proteome-of-the-rete-testis-fluid-from-tropically-adapted-morada-nova-rams
#4
Mauricio Fraga van Tilburg, Solange Damasceno Sousa, Révila Bianca Ferreira de Melo, Frederico B Moreno, Ana Cristina Monteiro-Moreira, Renato A Moreira, Arlindo de Alencar Moura
The rete testis has a close relationship with sperm development and may have other functions besides serving as an intercalated channel. The aim of this study was to identify and characterize the proteins of rete testis fluid (RTF) from tropically-adapted Morada Nova rams. Testicles obtained from six Morada Nova rams were dissected and the head of the epididymis was separated to access the efferent ducts. Rete testis fluid was obtained by gentle massage of the testis. The fluid was centrifuged to remove cell debris and sperm...
November 22, 2016: Animal Reproduction Science
https://www.readbyqxmd.com/read/27904607/a-bilobed-testicle-diagnosed-with-ultrasound-in-an-18-year-old-boy
#5
Farzaneh Hekmatnia, Mohammad Momeni, Ali Hekmatnia, Mohammad Mehdi Baradaran Mahdavi
Bilobed testicle is a very rare congenital malformation with an unknown etiology. Herein, we report an 18-year-old boy presented with a right-bilobed testicle mimicking a testicular tumor. The present case highlights the importance of considering bilobed testicle as a valuable differential diagnosis of testicular mass to prevent unnecessary surgery. Furthermore, the case could provide more information about presentation and management of bilobed testicle.
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/27900820/investigation-of-the-effects-of-kisspeptin-10-in-methionine-induced-lipid-peroxidation-in-testicle-tissue-of-young-rats
#6
Hatice Akkaya, Signem Eyuboglu, Gozde Erkanlı Senturk, Bayram Yilmaz
Disruption of the balance oxidants, antioxidants cause various pathophysiological conditions such as lipid peroxidation, protein degradation, or DNA damage. We have examined possible effects of kisspeptin-10 on the structural damage produced by methionine-induced lipid peroxidation in testicle tissue of young rats. Kisspeptin-10 did not significantly affect spermatogenic cells in seminiferous tubules. Testosterone levels decreased in the methionine group as compared with the control group but without statistical significance...
November 30, 2016: Journal of Biochemical and Molecular Toxicology
https://www.readbyqxmd.com/read/27898354/vasitis-mimicking-an-amyand-s-hernia-a-case-report
#7
Juan Manuel Romero Marcos, Santiago Baena Bradaschia, José María Muñoz Pérez, José Andrés Cifuentes Ródenas
INTRODUCTION: Amyand's hernia is an inguinal hernia containing the caecal appendix. It is usually an intraoperative finding, although it can be diagnosed preoperatively with radiologic examinations, which would show a tubular structure inside the inguinal canal. PRESENTATION OF CASE: A male patient presented to the emergency department complaining of abdominal pain in the right lower quadrant. He had been orchidectomized during his childhood due to cryptorchidism, and had been under antibiotic treatment a week before due to a suspected gonorrhoea...
November 22, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27894425/pediatric-testicular-torsion
#8
REVIEW
Paul R Bowlin, John M Gatti, J Patrick Murphy
The pediatric patient presenting with acute scrotal pain requires prompt evaluation and management given the likelihood of testicular torsion as the underlying cause. Although other diagnoses can present with acute testicular pain, it is important to recognize the possibility of testicular torsion because the best chance of testicular preservation occurs with expeditious management. When testicular torsion is suspected, prompt surgical exploration is warranted. A delay in surgical management should not occur in an effort to obtain confirmatory imaging...
February 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/27891737/role-of-resistance-physical-exercise-in-preventing-testicular-damage-caused-by-chronic-ethanol-consumption-in-uchb-rats
#9
Gessica Dutra Gonçalves, Nichelle Antunes Vieira, Henrique Rodrigues Vieira, Aline Dias Valério, Gláucia Elóisa Munhoz de Lion Siervo, Patricia Fernanda Felipe Pinheiro, Francisco Eduardo Martinez, Flávia Alessandra Guarnier, Giovana Rampazzo Teixeira, Glaura Scantamburlo Alves Fernandes
Ethanol consumption is associated with spermatogenesis damage and testosterone level alterations. Alcohol remains the most commonly used substance among athletes and sports enthusiasts. This study evaluated whether resistance physical exercise can reduce the testicular damage caused by ethanol exposure. A total of 36 ethanol drinking (UChB) rats were divided into four groups: C (control rats), ETOH (ethanol consumption), ETOH + T (ethanol consumption + physical training), and T (group physical training)...
November 28, 2016: Microscopy Research and Technique
https://www.readbyqxmd.com/read/27885104/could-vitamin-c-and-zinc-chloride-protect-the-germ-cells-against-sodium-arsenite
#10
L S Altoé, I B Reis, Mlm Gomes, H Dolder, Jc Monteiro Pirovani
Arsenic (As) is commonly associated with natural and human processes such as volcanic emissions, mining and herbicides production, being an important pollutant. Several studies have associated As intake with male fertility reduction, thus the aim of the present study was to evaluate whether vitamin C and/or zinc would counteract As side effects within the testicles. Adult male Wistar rats were divided into six experimental groups: control, sodium arsenite (5 mg/kg/day), vitamin C (100 mg/kg/day), zinc chloride (ZnCl2; 20 mg/kg/day), sodium arsenite + vitamin C and sodium arsenite + ZnCl2 Testicles and epididymis were harvested and either frozen or routinely processed to be embedded in glycol methacrylate resin...
November 24, 2016: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/27883967/case-report-of-migration-of-2-ventriculoperitoneal-shunt-catheters-to-the-scrotum-use-of-an-inguinal-incision-for-retrieval-diagnostic-laparoscopy-and-hernia-repair
#11
Caesar Ricci, Bratislav M Velimirovic, Tamara N Fitzgerald
BACKGROUD: Ventriculoperitoneal shunts are commonly used in the treatment of hydrocephalus, and catheter migration to various body sites has been reported. Pediatric and general surgeons are asked on occasion to assist with intraabdominal access for these shunts, particularly when there may be extensive adhesions or other complicating factors. METHODS: We describe a case in which an old shunt catheter was never removed from the abdomen, and it migrated through an inguinal hernia into the scrotum...
November 5, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27864728/variation-in-pestivirus-growth-in-testicle-primary-cell-culture-is-more-dependent-on-the-individual-cell-donor-than-cattle-breed
#12
Matheus N Weber, Fernando V Bauermann, Ninnet Gómez-Romero, Andy D Herring, Cláudio W Canal, John D Neill, Julia F Ridpath
The causes of bovine respiratory disease complex (BRDC) are multifactorial and include infection with both viral and bacterial pathogens. Host factors are also involved as different breeds of cattle appear to have different susceptibilities to BRDC. Infection with bovine pestiviruses, including bovine viral diarrhea virus 1 (BVDV1), BVDV2 and 'HoBi'-like viruses, is linked to the development of BRDC. The aim of the present study was to compare the growth of different bovine pestiviruses in primary testicle cell cultures obtained from taurine, indicine and mixed taurine and indicine cattle breeds...
November 18, 2016: Veterinary Research Communications
https://www.readbyqxmd.com/read/27830100/scrotal-involvement-with-testicular-nonseminomatous-germ-cell-tumour
#13
C G O'Leary, J A Allen, F O'Brien, A Tuthill, D G Power
A 37-year-old male presented with a traumatic injury to the scrotal region necessitating emergency surgery. Evacuation of a haematoma and bilateral orchidectomy were performed. A left sided nonseminomatous germ cell tumour (NSGCT), predominantly yolk sac, was identified. Microscopic margins were positive for tumour. Initial tumour markers revealed an AFP of 22,854 ng/mL, HCG of <1 mIU/mL, and LDH of 463 IU/L. Eight weeks after surgery, AFP levels remained elevated at 11,646 ng/mL. Computed tomography (CT) scanning demonstrated left inguinal adenopathy, 1...
2016: Case Reports in Oncological Medicine
https://www.readbyqxmd.com/read/27818621/diffuse-type-testicular-seminoma-in-a-stallion
#14
G Farjanikish, M Sayari, A Raisi, S Shirian
A 7-year-old stallion with progressive left testicular enlargement was presented. Grossly, the excised testicle measured 25 × 15 × 12 cm and weighed 3.7 kg. It was multinodular with a gray-white surface; however, the right testis was normal. Histologically, the neoplastic cells were disseminated diffusely in the tumoral stroma with a minimal fibrovascular stroma. Neoplastic cells were round to polygonal with abundant eosinophilic cytoplasm and large round to oval vesicular or hyperchromatic nucleous with a single prominent nucleolus...
2016: Comparative Clinical Pathology
https://www.readbyqxmd.com/read/27816924/men-s-knowledge-of-their-own-fertility-a-population-based-survey-examining-the-awareness-of-factors-that-are-associated-with-male-infertility
#15
D Daumler, P Chan, K C Lo, J Takefman, P Zelkowitz
STUDY QUESTION: How knowledgeable are men about the medical, environmental and psychological factors that are associated with male infertility? SUMMARY ANSWER: Men, across most demographic groups, have limited knowledge of the various factors that are associated with male infertility. WHAT IS KNOWN ALREADY: Few surveys have focused on men's knowledge of their own fertility. Studies of both men and women have found that men are comparatively less knowledgeable about issues of fertility and reproductive health...
November 5, 2016: Human Reproduction
https://www.readbyqxmd.com/read/27815687/seom-clinical-guidelines-for-the-management-of-germ-cell-testicular-cancer-2016
#16
J Aparicio, J Terrasa, I Durán, J R Germà-Lluch, R Gironés, E González-Billalabeitia, J Gumà, P Maroto, A Pinto, X García-Del-Muro
Testicular cancer represents the most common malignancy in males aged 15-34 years and is considered a model of curable neoplasm. Maintaining success, reducing treatment burden, and focusing on survivorship are then key objectives. Inguinal orchiectomy is the first recommended maneuver that has both diagnostic and therapeutic aims. Most patients are diagnosed with stage I disease (confined to the testicle). Close surveillance and selective, short-course adjuvant chemotherapy are accepted alternatives for these cases...
December 2016: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/27800069/-acute-scrotal-swellings-at-louga-regional-hospital-senegal-epidemiologic-etiologic-and-therapeutic-aspects
#17
Ibrahima Diabaté, Bouréima Ouédraogo, Mbaye Thiam
INTRODUCTION: Acute scrotal swellings (ASS) are a common reason for emergency consultation. This study aims to determine the frequency of hospitalization for ASS at the Louga Amadou Sakhir Mbaye Regional Hospital, Senegal, to identify its clinical forms and to evaluate the care management. METHODS: This is a retrospective descriptive study involving 114 patients hospitalized for ASS at the Louga Amadou Sakhir Mbaye regional hospital, from May 2010 to August 2013...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27796959/techniques-for-the-reprogramming-of-exogenous-stem-progenitor-cell-populations-towards-a-mammary-epithelial-cell-fate
#18
Gilbert H Smith, Corinne A Boulanger
This chapter considers the techniques necessary and required for the reprogramming of exogenous stem/progenitor cell populations towards a mammary epithelial cell fate. The protocols describe how to isolate cells from alternate mouse organs such as testicles of male mice and mix them with mammary cells to generate chimeric glands comprised of male and female epithelial cells that are fully competent. During the reformation of mammary stem cell niches by dispersed epithelial cells, in the context of the intact epithelium-free mammary stroma, non-mammary cells are sequestered and reprogrammed to perform mammary epithelial cell functions including those ascribed to mammary stem/progenitor cells...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27788270/testicular-steroidogenesis-and-locomotor-activity-are-regulated-by-gonadotropin-inhibitory-hormone-in-male-european-sea-bass
#19
José A Paullada-Salmerón, Mairi Cowan, María Aliaga-Guerrero, José F López-Olmeda, Evaristo L Mañanós, Silvia Zanuy, José A Muñoz-Cueto
Gonadotropin-inhibitory hormone (GnIH) is a neurohormone that suppresses reproduction by acting at both the brain and pituitary levels. In addition to the brain, GnIH may also be produced in gonads and can regulate steroidogenesis and gametogenesis. However, the function of GnIH in gonadal physiology has received little attention in fish. The main objective of this study was to evaluate the effects of peripheral sbGnih-1 and sbGnih-2 implants on gonadal development and steroidogenesis during the reproductive cycle of male sea bass (Dicentrarchus labrax)...
2016: PloS One
https://www.readbyqxmd.com/read/27782186/opposite-sex-attraction-in-male-mice-requires-testosterone-dependent-regulation-of-adult-olfactory-bulb-neurogenesis
#20
Roberta Schellino, Sara Trova, Irene Cimino, Alice Farinetti, Bart C Jongbloets, R Jeroen Pasterkamp, Giancarlo Panzica, Paolo Giacobini, Silvia De Marchis, Paolo Peretto
Opposite-sex attraction in most mammals depends on the fine-tuned integration of pheromonal stimuli with gonadal hormones in the brain circuits underlying sexual behaviour. Neural activity in these circuits is regulated by sensory processing in the accessory olfactory bulb (AOB), the first central station of the vomeronasal system. Recent evidence indicates adult neurogenesis in the AOB is involved in sex behaviour; however, the mechanisms underlying this function are unknown. By using Semaphorin 7A knockout (Sema7A ko) mice, which show a reduced number of gonadotropin-releasing-hormone neurons, small testicles and subfertility, and wild-type males castrated during adulthood, we demonstrate that the level of circulating testosterone regulates the sex-specific control of AOB neurogenesis and the vomeronasal system activation, which influences opposite-sex cue preference/attraction in mice...
October 26, 2016: Scientific Reports
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