keyword
Keywords Probiotic stimulator interleuk...

Probiotic stimulator interleukin 10

https://read.qxmd.com/read/37224578/streptococcus-lactarius-mb622-and-streptococcus-salivarius-mb620-isolated-from-human-milk-reduce-chemokine-il-8-production-in-response-to-tnf-%C3%AE-in-caco-2-cell-line-an-exploratory-study
#21
JOURNAL ARTICLE
Ayesha Saeed, Azra Yasmin, Mehreen Baig, Muhammad Arslan Ahmed, Zia-Ur-Rehman Farooqi
Streptococci are a predominant genera of the human milk microbiome. Among different lactic acid bacteria (LAB) a few Streptococcal strains are also considered as probiotics. Probiotic bacteria are reported to modulate immunity when consumed in adequate amount and bacterial hydrophobicity can be considered as a preliminary experiment for the adhesive capability of probiotic bacteria to the epithelial cells. The present study aimed to investigate the probiotic, hydrophobic and immune modulation property of Streptococcus lactarius MB622 and Streptococcus salivarius MB620, isolated from human milk...
May 22, 2023: Cytokine
https://read.qxmd.com/read/37110385/in-vitro-preventive-effect-and-mechanism-of-action-of-weissella-cibaria-cmu-against-streptococcus-mutans-biofilm-formation-and-periodontal-pathogens
#22
JOURNAL ARTICLE
Mi-Sun Kang, Geun-Yeong Park, A-Reum Lee
In this study, we evaluated the in vitro anti-biofilm, antibacterial, and anti-inflammatory activity of Weissella cibaria CMU (CMU), an oral probiotic, against periodontopathogens. Compared to other oral probiotics, CMU showed a superior inhibitory effect on the biofilm formation and growth of Streptococcus mutans on orthodontic wires and artificial teeth ( p < 0.05). CMU exerted potent antibacterial effects against S. mutans and Porphyromonas gingivalis according to a line test. In human gingival fibroblasts (HGFs) stimulated by P...
April 7, 2023: Microorganisms
https://read.qxmd.com/read/37089407/-in-vitro-evaluation-of-lactiplantibacillus-plantarum-hokkaido-strain-effective-lactic-acid-bacteria-for-calf-diarrhea
#23
JOURNAL ARTICLE
Mari Ikehata, Satoru Konnai, Tomohiro Okagawa, Kentaro Abe, Mitsuru Honma, Toru Kitamura, Naoya Maekawa, Yasuhiko Suzuki, Shiro Murata, Kazuhiko Ohashi
Calf diarrhea adversely affects growth and sometimes results in mortality, leading to severe economic losses to the cattle industry. Antibiotics are useful in the treatment against bacterial diarrhea, but not against viral, protozoan, and antibiotic-resistant bacterial diarrhea. Therefore, there are growing requirements for a novel control method for calf diarrhea. Probiotics have been considered promising candidates for preventive and supportive therapy for calf diarrhea for many years. A recent study has revealed that Lactiplantibacillus plantarum HOKKAIDO strain (Lp-HKD) reduces intestinal pathology and the severity of diarrhea in bovine rotavirus (BRV)-infected calves...
2023: Frontiers in Veterinary Science
https://read.qxmd.com/read/36914312/development-of-innovative-fermented-products-by-exploiting-the-diversity-of-immunomodulatory-properties-and-fermentative-activity-of-lactic-and-propionic-acid-bacteria
#24
JOURNAL ARTICLE
Nassima Illikoud, Fillipe Luiz Rosa do Carmo, Nathalie Daniel, Gwénaël Jan, Valérie Gagnaire
Many consumers nowadays demand plant-based milk analogs for reasons related to lifestyle, health, diet and sustainability. This has led to the increasing development of new products, fermented or not. The objective of the present study was to develop a plant-based fermented product (based on soy milk analog or on hemp milk analog), as well as mixes, using lactic acid bacteria (LAB) and propionic acid bacteria (PAB) strains, as well as consortia thereof. We screened a collection of 104 strains, from nine LAB species and two PAB species, based on their ability to ferment plant or milk carbohydrates, to acidify goat milk, soy milk analog and hemp milk analog, as well as to hydrolyze proteins isolated from these three products...
April 2023: Food Research International
https://read.qxmd.com/read/36909859/efficacies-of-potential-probiotic-candidates-isolated-from-traditional-fermented-korean-foods-in-stimulating-immunoglobulin-a-secretion
#25
JOURNAL ARTICLE
Chang-Yong Choi, Chang-Hee Lee, Jun Yang, Seok-Jin Kang, In-Byung Park, Si-Won Park, Na-Young Lee, Hyun-Been Hwang, Hyun Sun Yun, Taehoon Chun
The aim of this study was to evaluate efficacies of selected lactic acid bacteria (LAB) in inducing immunoglobulin A (IgA) secretion. Twenty-five different LAB isolated from traditional fermented Korean foods were characterized for their probiotic properties and screened to identify those that could stimulate lamina propria cells (LPCs) from Peyer's patch to secret IgA in vitro . Among them, four strains ( Lactiplantibacillus plantarum CJW55-10, Lactiplantibacillus pentosus CJW18-6, L. pentosus CJW56-11, and Pediococcus acidilactici CJN2696) were found to be strong IgA inducers...
March 2023: Food science of animal resources
https://read.qxmd.com/read/36884184/the-effect-of-akkermansia-muciniphila-and-its-outer-membrane-vesicles-on-micrornas-expression-of-inflammatory-and-anti-inflammatory-pathways-in-human-dendritic-cells
#26
JOURNAL ARTICLE
Laya Zoghi Mofrad, Abolfazl Fateh, Fattah Sotoodehnejadnematalahi, Dariush Norouzian Sham Asbi, Seyed Davar Siadat
Probiotics play a crucial role in immunomodulation by regulating dendritic cell (DC) maturation and inducing tolerogenic DCs. Akkermansia muciniphila affects inflammatory response by elevating inhibitory cytokines. We aimed to evaluate whether Akkermansia muciniphila and its outer membrane vesicles (OMVs) affect microRNA-155, microRNA-146a, microRNA-34a, and let-7i expression of inflammatory and anti-inflammatory pathways. Peripheral blood mononuclear cells (PBMCs) were isolated from the healthy volunteers...
March 8, 2023: Probiotics and Antimicrobial Proteins
https://read.qxmd.com/read/36838243/modulatory-effects-of-heat-inactivated-streptococcus-thermophilus-strain-7-on-the-inflammatory-response-a-study-on-an-animal-model-with-tlr3-induced-intestinal-injury
#27
JOURNAL ARTICLE
Gilbert Aaron Lee, Yu-Wei Chang, Wan-Li Lin, Yu-Chen S H Yang, Wei-Jen Chen, Fu-Huan Huang, Yun-Ru Liu
Rotavirus infections result in severe gastroenteritis with a detrimental inflammatory response in the intestine. Because probiotics have an anti-inflammatory effect and can modulate the gut microbiota profile, they can be used as a biotherapy for inflammatory intestinal diseases. In this study, we isolated Streptococcus thermophilus strain 7 (ST7) from cow milk and examined the effect of heat-inactivated ST7 on the intestinal histopathological score, inflammatory cytokine levels, T-cell activation and effector function, and microbiome profile in a mouse model with intestinal injury induced by polyinosinic-polycytidylic acid (poly I:C), a Toll-like receptor 3 agonist...
January 20, 2023: Microorganisms
https://read.qxmd.com/read/36812033/immunostimulatory-effects-of-dairy-probiotic-strains-bifidobacterium-animalis-ssp-lactis-hy8002-and-lactobacillus-plantarum-hy7717
#28
JOURNAL ARTICLE
Ju-Yeon Kim, Joo Yun Kim, Hyeonji Kim, Eun Chae Moon, Keon Heo, Jae-Jung Shim, Jung-Lyoul Lee
Previous studies reported that Bifidobacterium animalis ssp. lactis HY8002 (HY8002) improved intestinal integrity and had immunomodulatory effects. Lactobacillus plantarum HY7717 (HY7717) was screened in vitro from among 21 other lactic acid bacteria (LAB) and demonstrated nitric oxide (NO) production. The aims of this study were to investigate the individual and combined ex vivo and in vivo effects of LAB strains HY8002 and HY7717 at immunostimulating mice that have been challenged with an immunosuppressant drug...
November 2022: Journal of Animal Science and Technology
https://read.qxmd.com/read/36590538/distribution-cholesterol-lowering-and-immunomodulation-effects-of-lactic-acid-bacteria-from-fermented-mussel-hoi-dong
#29
JOURNAL ARTICLE
Engkarat Kingkaew, Hiroshi Konno, Yoshihito Hosaka, Wongsakorn Phongsopitanun, Somboon Tanasupawat
Forty-eight lactic acid bacteria (LAB) isolated from fermented mussels in Thailand were evaluated for their probiotic properties, bile salt hydrolase (BSH), cholesterol assimilation and immunomodulatory effects. They were identified as Companilactobacillus formosensis (Group I, 10 isolates), Lentilactobacillus buchneri (Group II, 8 isolates), Lactiplantibacillus plantarum subsp. plantarum (Group III, 16 isolates), Lacticaseibacillus rhamnosus (Group IV, 1 isolate), Pediococcus pentosaceus (Group V, 5 isolates) and P...
December 2022: Heliyon
https://read.qxmd.com/read/36422317/immunostimulatory-activity-of-lactic-acid-bacteria-cell-free-supernatants-through-the-activation-of-nf-%C3%AE%C2%BAb-and-mapk-signaling-pathways-in-raw-264-7-cells
#30
JOURNAL ARTICLE
Jaekoo Lee, Seonyoung Kim, Chang-Ho Kang
Lactic acid bacteria (LAB) can improve host health and has strong potential for use as a health functional food. Specific strains of LAB have been reported to exert immunostimulatory effects. The primary goal of this study was to evaluate the immunostimulatory activities of novel LAB strains isolated from humans and foods and to investigate the probiotic properties of these strains. Cell-free supernatants (CFS) obtained from selected LAB strains significantly increased phagocytosis and level of nitric oxide (NO) and pro-inflammatory cytokines such as tumor necrosis factor (TNF)-α and interleukin (IL)-6 in RAW264...
November 13, 2022: Microorganisms
https://read.qxmd.com/read/36415572/investigation-of-immunostimulatory-effects-of-heat-treated-lactiplantibacillus-plantarum-lm1004-and-its-underlying-molecular-mechanism
#31
JOURNAL ARTICLE
Won-Young Bae, Woo-Hyun Jung, So Lim Shin, Seulgi Kwon, Minn Sohn, Tae-Rahk Kim
Postbiotics are defined as probiotics inactivated by heat, ultraviolet radiation, sonication, and other physical or chemical stresses. Postbiotics are more stable than probiotics, and these properties are advantageous for food additives and pharmacological agents. This study investigated the immunostimulatory effects of heat-treated Lactiplantibacillus plantarum LM1004 (HT-LM1004). Cellular fatty acid composition of L. plantarum LM1004 isolated form kimchi was analyzed by gas chromatography-mass spectrometry detection system...
November 2022: Food science of animal resources
https://read.qxmd.com/read/36362221/-lactobacillus-sakei-mjm60958-as-a-potential-probiotic-alleviated-non-alcoholic-fatty-liver-disease-in-mice-fed-a-high-fat-diet-by-modulating-lipid-metabolism-inflammation-and-gut-microbiota
#32
JOURNAL ARTICLE
Huong Thi Nguyen, Mingkun Gu, Pia Werlinger, Joo-Hyung Cho, Jinhua Cheng, Joo-Won Suh
Non-alcoholic fatty liver disease (NAFLD) is a common liver disease with a rapidly increasing number of cases worldwide. This study aimed to evaluate the effects of Lactobacillus sakei MJM60958 (MJM60958) on NAFLD in vitro and in vivo. In in vitro tests, MJM60958 significantly inhibited lipid accumulation by 46.79% in HepG2 cells stimulated with oleic acid and cholesterol (OA-C). Moreover, MJM60958 showed safe and probiotic characteristics in vitro. In the animal study, MJM60958 administration in a high-fat diet-induced NAFLD mouse model significantly reduced body weight and liver weight, and controlled aspartate aminotransferase (ALT), aspartate transaminase (AST), triglyceride (TG), urea nitrogen (BUN), and uric acid (UA) levels in the blood, which are features of NAFLD...
November 3, 2022: International Journal of Molecular Sciences
https://read.qxmd.com/read/36224643/dietary-supplementation-of-macleaya-cordata-extract-and-bacillus-in-combination-improve-laying-performance-by-regulating-reproductive-hormones-intestinal-microbiota-and-barrier-function-of-laying-hens
#33
JOURNAL ARTICLE
Fei Wang, Peng Zou, Shujie Xu, Qi Wang, Yuanhao Zhou, Xiang Li, Li Tang, Baikui Wang, Qian Jin, Dongyou Yu, Weifen Li
BACKGROUND: This study aimed to investigate whether the combination of Macleaya cordata extract (MCE) and Bacillus could improve the laying performance and health of laying hens better. METHODS: A total of 360 29-week-old Jingbai laying hens were randomly divided into 4 treatments: control group (basal diet), MCE group (basal diet + MCE), Probiotics Bacillus Compound (PBC) group (basal diet + compound Bacillus), MCE + PBC group (basal diet + MCE + compound Bacillus)...
October 13, 2022: Journal of Animal Science and Biotechnology
https://read.qxmd.com/read/36178579/immune-enhancing-effect-of-heat-treated-levilactobacillus-brevis-ku15159-in-raw-264-7-cells
#34
JOURNAL ARTICLE
Chang-Hoon Hwang, Kee-Tae Kim, Na-Kyoung Lee, Hyun-Dong Paik
Probiotics are alive microbes that present beneficial to the human's health. They influence immune responses through stimulating antibody production, activating T cells, and altering cytokine expression. The probiotic characteristics of Levilactobacillus brevis KU15159 were evaluated on the tolerance and adherence to gastrointestinal conditions. L. brevis KU15159 was safe in a view of producing various useful enzymes and antibiotic sensitivity. Heat-treated L. brevis KU15159 increased production of nitric oxide (NO) and phagocytic activity in RAW 264...
September 30, 2022: Probiotics and Antimicrobial Proteins
https://read.qxmd.com/read/36157148/current-medical-treatment-for-alcohol-associated-liver-disease
#35
REVIEW
Gustavo Ayares, Francisco Idalsoaga, Luis A Díaz, Jorge Arnold, Juan P Arab
Alcohol-associated liver disease is one of the main causes of chronic liver disease. It comprises a clinical-histologic spectrum of presentations, from steatosis, steatohepatitis, to different degrees of fibrosis, including cirrhosis and severe necroinflammatory disease, called alcohol-associated hepatitis. In this focused update, we aim to present specific therapeutic interventions and strategies for the management of alcohol-associated liver disease. Current evidence for management in all spectra of manifestations is derived from general chronic liver disease recommendations, but with a higher emphasis on abstinence and nutritional support...
2022: Journal of Clinical and Experimental Hepatology
https://read.qxmd.com/read/36076276/lactobacillus-rhamnosus-gr-1-attenuates-foodborne-bacillus-cereus-induced-nlrp3-inflammasome-activity-in-bovine-mammary-epithelial-cells-by-protecting-intercellular-tight-junctions
#36
JOURNAL ARTICLE
Qiang Shan, Ning Liu, Xue Wang, Yaohong Zhu, Jinhua Yin, Jiufeng Wang
BACKGROUND: Bacillus cereus is an important pathogen that causes human food poisoning, specifically diarrhea and vomiting. B. cereus can also induce mastitis in dairy cows and has a strong survival ability in milk, as it cannot be inactivated by high-temperature short-time pasteurization. Therefore, B. cereus can enter the market through pasteurized milk and other dairy products, imposing enormous hidden dangers on food safety and human health. RESULTS: In this study, B...
September 9, 2022: Journal of Animal Science and Biotechnology
https://read.qxmd.com/read/36012836/structural-features-and-immunomodulatory-effects-of-water-extractable-polysaccharides-from-macrolepiota-procera-scop-singer
#37
JOURNAL ARTICLE
Yordan Nikolaev Georgiev, Ondrej Vasicek, Balik Dzhambazov, Tsvetelina Georgieva Batsalova, Petko Nedyalkov Denev, Lili Ivaylova Dobreva, Svetla Trifonova Danova, Svetlana Dimitrova Simova, Christian Winther Wold, Manol Hristov Ognyanov, Berit Smestad Paulsen, Albert Ivanov Krastanov
Macrolepiota procera (MP) is an edible mushroom used in the treatment of diabetes, hypertension and inflammation. However, the structure and biological effects of its polysaccharides (PSs) are unclear. This study investigates the structural features of a PS complex from MP (MP-PSC), its immunomodulatory activities and effects on probiotic and pathogenic bacteria. MP-PSC was obtained by boiling water, and PSs were characterized by 2D NMR spectroscopy. The immunomodulatory effects on blood and derived neutrophils, other leukocytes, and murine macrophages were studied by flow cytometry, chemiluminescence, spectrophotometry, and ELISA...
August 13, 2022: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/36000874/lacticaseibacillus-rhamnosus-lcr35-stimulates-epithelial-vaginal-defenses-upon-gardnerella-vaginalis-infection
#38
JOURNAL ARTICLE
Sylvie Miquel, Julien Verlaguet, Sophie Garcin, Thomas Bertran, Bertrand Evrard, Christiane Forestier, Marjolaine Vareille-Delarbre
Dysbiosis of the vaginal microbiome as a result of overgrowth of anaerobic bacteria, such as Gardnerella vaginalis, and low levels of "healthy" lactobacilli leads to bacterial vaginosis (BV), usually associated with a low-grade inflammatory process. Despite appropriate antibiotic treatment, G. vaginalis -associated BV is characterized by significant recurrence. The use of probiotics could be an interesting alternative therapy due to their ability to rebalance vaginal microbiota. In this study, we investigated the effects of a well-characterized probiotic strain, Lacticaseibacillus rhamnosus Lcr35, on epithelial vaginal and dendritic cell (DC) immune responses after G...
September 15, 2022: Infection and Immunity
https://read.qxmd.com/read/35987935/probiogenomic-analysis-of-lactiplantibacillus-sp-lm14-2-from-fermented-mussel-hoi-dong-and-evaluation-of-its-cholesterol-lowering-and-immunomodulation-effects
#39
JOURNAL ARTICLE
Engkarat Kingkaew, Hiroshi Konno, Yoshihito Hosaka, Somboon Tanasupawat
Lactiplantibacillus sp. LM14-2, isolated from Thai-fermented mussel (Hoi-dong), showed attractive probiotic properties. This strain was identified as Lactiplantibacillus plantarum based on its phenotypic, chemotaxonomic, and genetic characteristics including whole-genome sequencing (WGS). The draft genome sequence was analyzed and annotated for the molecular mechanisms involved in the safety assessment, the adaptation and adhesion of L. plantarum LM14-2 to the gastrointestinal tract (GIT), and the beneficial genes involved in bacteria-host interactions...
August 20, 2022: Probiotics and Antimicrobial Proteins
https://read.qxmd.com/read/35939865/effects-of-potential-probiotics-on-the-expression-of-cytokines-and-human-%C3%AE-defensins-in-human-gingival-epithelial-cells-and-in-vivo-efficacy-in-a-dog-model
#40
RANDOMIZED CONTROLLED TRIAL
Nuntiya Pahumunto, Yada Duangnumsawang, Rawee Teanpaisan
OBJECTIVES: The aims of this study were to examine the effects of probiotic strains on the expression of cytokines and human β-defensins-2-4 in human gingival epithelial cells and to investigate the in vivo efficacy of probiotics in a dog model. DESIGN: Selected probiotics, Lacticaseibacillus paracasei SD1, L. rhamnosus SD4, L. rhamnosus SD11 and Limosilactobacillus fermentum SD7, were examined for the expression of human β-defensins-2-4, and cytokine responses after stimulated by various periodontopathogens...
October 2022: Archives of Oral Biology
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