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https://www.readbyqxmd.com/read/28918612/increase-concentration-of-transforming-growth-factor-beta-tgf-%C3%AE-in-breast-milk-of-mothers-with-psychological-disorders
#1
Mamak Shariat, Nasrin Abedinia, Nima Rezaei, Nahid Farrokhzad
Several studies have shown an imbalance between proinflammatory and anti-inflammatory cytokines in depression and anxiety disorders. However, less attention has been paid to the role of cytokines in psychological disorder in mothers who breastfeed. This study looks at whether concentration levels of TGF-β2 are altered in anxious and depressive breastfeeding mothers. This study checked the concentration level of TGF-B2 in relation with psychological symptoms on 110 breastfeeding mothers; based on random sampling method with using of Beck Depression Inventory (BDI), General Health Questionnaire (GHQ) and Spielberger Stress Scale (STAI) in 2015 also TGF-β2 was measured in breast milk using ELISA...
July 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/28918065/the-role-of-epigenetics-in-lysosomal-storage-disorders-uncharted-territory
#2
REVIEW
Shahzeb Hassan, Ellen Sidransky, Nahid Tayebi
The study of the contribution of epigenetic mechanisms, including DNA methylation, histone modifications, and microRNAs, to human disease has enhanced our understanding of different cellular processes and diseased states, as well as the effect of environmental factors on phenotypic outcomes. Epigenetic studies may be particularly relevant in evaluating the clinical heterogeneity observed in monogenic disorders. The lysosomal storage disorders are Mendelian disorders characterized by a wide spectrum of associated phenotypes, ranging from neonatal presentations to symptoms that develop in late adulthood...
August 1, 2017: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/28917365/a-systematic-review-of-the-efficacy-and-safety-of-rosa-damascena-mill-with-an-overview-on-its-phytopharmacological-properties
#3
REVIEW
Neda Nayebi, Nahid Khalili, Mohammad Kamalinejad, Majid Emtiazy
Rosa damascena Mill. is one of the most famous ornamental plants cultivated all over the world mostly for perfumery industries. Traditionally it has been used as an astringent, analgesic, cardiac and intestinal tonic.The paucity ofauthoritative monographs urged usto summarize its clinical effectiveness and safety with acomprehensive review of the literature. "PUBMED", "SCOPUS", "WEBOF SCIENCE" were searched up to April 30, 2017 with search terms:("Rosa damascena" OR "Damask Rose"). All human studies with any mono-preparation were included...
October 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28915995/detection-and-molecular-characterization-of-feline-hemoplasmas-in-wild-felid-species-in-iran-in-the-middle-east
#4
Fereshteh Ghazisaeedi, Nahid Atyabi, Taghi Zahraei Salehi, Saeid Tabatabaei, Iraj Ashrafi Tamai, Iman Memarian, Séverine Tasker
Three feline hemoplasma species exist in felids: Mycoplasma haemofelis, 'Candidatus Mycoplasma haemominutum', and 'Candidatus Mycoplasma turicensis'. The aims of the study were to determine the presence of, and molecularly characterize, any hemoplasmas in wild felids, including the endangered Persian leopard in Iran, the Middle East. Blood samples were collected from 19 wild felids, including three Persian leopards. Using species-specific hemoplasma PCRs and ELISA serological testing for feline leukaemia virus and feline immunodeficiency virus (FIV), two Persian leopards were found to be infected with 'Ca...
October 2017: Comparative Immunology, Microbiology and Infectious Diseases
https://www.readbyqxmd.com/read/28904505/embryo-cryopreservation-following-in-vitro-maturation-for-fertility-preservation-in-a-woman-with-mullerian-adenosarcoma-a-case-report
#5
Mehdi Mohsenzadeh, Mohammad A Khalili, Nasim Tabibnejad, Nahid Yari, Azam Agha-Rahimi, Mojgan Karimi-Zarchi
In-vitro maturation (IVM) of the immature oocytes recovered from the surgically removed ovarian tissue has been considered as a process for fertility preservation in patients with cancer. Fertility preservation for a woman with Mullerian adenocarcinoma. A 37-year-old woman with Mullerian adenocarcinoma was a candidate for ovarian resection. The immature oocytes were retrieved after ovarian resection from a 37-year-old woman with Mullerian adenocarcinoma. The oocytes underwent IVM and were fertilized using intracytoplasmic sperm injection (ICSI)...
April 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/28901680/evaluation-of-polyacrylonitrile-electrospun-nano-fibrous-mats-as-leukocyte-removal-filter-media
#6
Raha Pourbaghi, Mohammad Zarrebini, Dariush Semnani, Abbasali Pourazar, Nahid Akbari, Reihaneh Shamsfar
Removal of leukocytes from blood products is the most effective means for elimination of undesirable side effects and prevention of possible reactions in recipients. Micro-fibrous mats are currently used for removal of leukocytes from blood. In this study, samples of electrospun nano-fibrous mats were produced. The performance of the produced electrospun nano-fibrous mats as means of leukocytes removal from fresh whole blood was both evaluated and compared with that of commercially available micro-fibrous mats...
September 13, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28899362/nationwide-cross-sectional-survey-of-schistosomiasis-and-soil-transmitted-helminthiasis-in-sudan-study-protocol
#7
Seungman Cha, Sung-Tae Hong, Young-Ha Lee, Keon Hoon Lee, Dae Seong Cho, Jinmoo Lee, Jong-Yil Chai, Mousab Siddig Elhag, Soheir Gabralla Ahmad Khaled, Mustafa Khidir Mustafa Elnimeiri, Nahid Abdelgadeir Ali Siddig, Hana Abdelrazig, Sarah Awadelkareem, Azza Tag Eldin Elshafie, Hassan Ahmed Hassan Ahmed Ismail, Mutamad Amin
BACKGROUND: Schistosomiasis and soil-transmitted helminthiasis (STHs) are target neglected tropical diseases (NTDs) of preventive chemotherapy, but the control and elimination of these diseases have been impeded due to resource constraints. Few reports have described study protocol to draw on when conducting a nationwide survey. We present a detailed methodological description of the integrated mapping of schistosomiasis and STHs on the basis of our experiences, hoping that this protocol can be applied to future surveys in similar settings...
September 12, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28894711/the-increasing-trend-in-global-ranking-of-websites-of-iranian-medical-universities-during-january-2012-2015
#8
Nahid Ramezan Ghorbani, Yousef Fakour, Seyed Ali Nojoumi
BACKGROUND: Researchers and academic institutions need assessment and rating to measure their performance. The criteria are designed to evaluate quality and adequacy of research and welcome by most universities as an international process to increase monitoring academic achievements. The study aimed to evaluate the increasing trend in global ranking of Iranian medical universities websites emphasizing on comparative approach. METHODS: This is a cross-sectional study involving websites of Iranian medical universities...
August 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28881671/malignant-pericytes-expressing-gt198-give-rise-to-tumor-cells-through-angiogenesis
#9
Liyong Zhang, Yan Wang, Mohammad H Rashid, Min Liu, Kartik Angara, Nahid F Mivechi, Nita J Maihle, Ali S Arbab, Lan Ko
Angiogenesis promotes tumor development. Understanding the crucial factors regulating tumor angiogenesis may reveal new therapeutic targets. Human GT198 (PSMC3IP or Hop2) is an oncoprotein encoded by a DNA repair gene that is overexpressed in tumor stromal vasculature to stimulate the expression of angiogenic factors. Here we show that pericytes expressing GT198 give rise to tumor cells through angiogenesis. GT198(+) pericytes and perivascular cells are commonly present in the stromal compartment of various human solid tumors and rodent xenograft tumor models...
August 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/28881154/preconditioning-with-morphine-protects-hippocampal-ca1-neurons-against-ischemia-reperfusion-injury-via-the-activation-of-the-mtor-pathway
#10
Maedeh Arabian, Nahid Aboutaleb, Mansoureh Soleimani, Marjan Ajami, Rouhollah Habibey, Yousef Rezaei, Hamidreza Pazoki-Toroudi
In the present study, we examined the role of mammalian target of rapamycin (mTOR) to reveal the neuroprotective effects of chronic morphine preconditioning on the hippocampus following ischemia/reperfusion (I/R) injury. Morphine was administrated for 5 days twice a day before I/R injury induction. The role of mTOR was evaluated by the injection of rapamycin (5 mg/kg, ip) before I/R injury. The passive avoidance test was used to evaluate memory. Neuronal density and apoptosis were measured in the CA1 region, 72 hours after the induction of I/R injury...
September 7, 2017: Canadian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/28875006/aberrant-methylation-mediated-suppression-of-apaf1-in-myelodysplastic-syndrome
#11
Farhad Zaker, Nahid Nasiri, Naser Amirizadeh, Seyed Mohsen Razavi, Marjan Yaghmaie, Ladan Teimoori-Toolabi, Ali Maleki, Masoumeh Bakhshayesh
Background: Myelodysplastic syndromes (MDSs) include a diverse group of clonal bone marrow disorders characterized by ineffective hematopoiesis and pancytopenia. It was found that down regulation of APAF1, a putative tumor suppressor gene (TSG), leads to resistance to chemotherapy and disease development in some cancers. In this study, we investigated the relation of APAF1 methylation status with its expression and clinicopathological factors in myelodysplastic syndrome (MDS) patients. Materials andMethods: Methylation Sensitive-High Resolution Melting Curve Analysis (MS-HRM) was employed in studying the methylation of CpG islands in the APAF1promoter region in MDS...
April 1, 2017: International Journal of Hematology-oncology and Stem Cell Research
https://www.readbyqxmd.com/read/28871024/telemedicine-guided-education-on-secondary-stroke-and-fall-prevention-following-inpatient-rehabilitation-for-texas-patients-with-stroke-and-their-caregivers-a-feasibility-pilot-study
#12
Mansi M Jhaveri, Ruby Benjamin-Garner, Nahid Rianon, Mark Sherer, Gerard Francisco, Farhaan Vahidy, Kayta Kobayashi, Mary Gaber, Paige Shoemake, Kim Vu, Alyssa Trevino, James Grotta, Sean Savitz
INTRODUCTION: The aftermath of stroke leaves many consequences including cognitive deficits and falls due to imbalance. Stroke survivors and families struggle to navigate the complex healthcare system with little assistance posthospital discharge, often leading to early hospital readmission and worse stroke outcomes. Telemedicine Guided Education on Secondary Stroke and Fall Prevention Following Inpatient Rehabilitation feasibility study examines whether stroke survivors and their caregivers find value in telerehabilitation (TR) home visits that provide individualised care and education by a multidisciplinary team after discharge from inpatient rehabilitation...
September 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/28868246/antimicrobial-properties-of-amniotic-and-chorionic-membranes-a-comparative-study-of-two-human-fetal-sacs
#13
Majid Zare-Bidaki, Sajad Sadrinia, Soheila Erfani, Ehsan Afkar, Nahid Ghanbarzade
BACKGROUND: There is evidence of antibacterial properties of human chorioamniotic layer. However, the distinctive contribution of its individual parts, amniotic and chorionic membranes, to these effects is still unknown. The aim of present study was comparison of the antibacterial effects between amniotic and chorionic membranes. METHODS: Chorioamniotic layer was removed from placenta belonging to 43 healthy mothers whose infants were delivered by caesarean section...
April 2017: Journal of Reproduction & Infertility
https://www.readbyqxmd.com/read/28854633/contrasting-patterns-of-nucleotide-substitution-rates-provide-insight-into-dynamic-evolution-of-plastid-and-mitochondrial-genomes-of-geranium
#14
Seongjun Park, Tracey A Ruhlman, Mao-Lun Weng, Nahid H Hajrah, Jamal S M Sabir, Robert K Jansen
Geraniaceae have emerged as a model system for investigating the causes and consequences of variation in plastid and mitochondrial genomes. Incredible structural variation in plastid genomes (plastomes) and highly accelerated evolutionary rates have been reported in selected lineages and functional groups of genes in both plastomes and mitochondrial genomes (mitogenomes), and these phenomena have been implicated in cytonuclear incompatibility. Previous organelle genome studies have included limited sampling of Geranium, the largest genus in the family with over 400 species...
June 1, 2017: Genome Biology and Evolution
https://www.readbyqxmd.com/read/28852666/designing-a-model-of-patient-tracking-system-for-natural-disaster-in-iran
#15
Nahid Tavakoli, Mohammad H Yarmohammadian, Reza Safdari, Mahmoud Keyvanara
CONTEXT: Disaster patient tracking consists of identifying and registering patients, recording data on their medical conditions, settings priorities for evacuation of scene, locating the patients from scene to health care centers and then till completion of treatment and discharge. AIM: The aim of this study was to design a model of patient tracking system for natural disaster in Iran. MATERIALS AND METHODS: This applied study was conducted in two steps in 2016...
2017: Journal of Education and Health Promotion
https://www.readbyqxmd.com/read/28845407/the-prevalence-of-psychiatric-distress-and-associated-risk-factors-among-college-students-using-ghq-28-questionnaire
#16
Jalal Poorolajal, Ali Ghaleiha, Nahid Darvishi, Shahla Daryaei, Soheila Panahi
BACKGROUND: Adolescent and young adults are at increased risk of psychiatric distress and serious disability. We estimated the prevalence and associated risk factors of psychiatric distress among the college students of Hamadan University of Medical Sciences, Iran. METHODS: We performed this cross-sectional study, from Jan to May 2016 at Hamadan University of Medical Sciences, Hamadan, Iran. Students filled out voluntarily an anonymous self-administered questionnaire, including demographic characteristics, personal information, behavioral risk factors, and a validated Persian version of the GHQ-28 questionnaire, including somatic symptoms (items 1-7), anxiety/insomnia (items 8-14), social dysfunctions (items 15-21), and severe depression (items 22-28)...
July 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28844166/nurses-burnout-the-influence-of-leader-empowering-behaviors-work-conditions-and-demographic-traits
#17
Rola H Mudallal, Wafa'a M Othman, Nahid F Al Hassan
Nurse burnout is a widespread phenomenon characterized by a reduction in nurses' energy that manifests in emotional exhaustion, lack of motivation, and feelings of frustration and may lead to reductions in work efficacy. This study was conducted to assess the level of burnout among Jordanian nurses and to investigate the influence of leader empowering behaviors (LEBs) on nurses' feelings of burnout in an endeavor to improve nursing work outcomes. A cross-sectional and correlational design was used. Leader Empowering Behaviors Scale and the Maslach Burnout Inventory (MBI) were employed to collect data from 407 registered nurses, recruited from 11 hospitals in Jordan...
January 1, 2017: Inquiry: a Journal of Medical Care Organization, Provision and Financing
https://www.readbyqxmd.com/read/28843238/assessment-of-the-prevalence-and-risk-factors-associated-with-glucocorticoid-induced-diabetes-mellitus-in-pemphigus-vulgaris-patients
#18
Abbas Darjani, Nahid Nickhah, Mohammad Hassan Hedayati Emami, Narges Alizadeh, Rana Rafiei, Hojat Eftekhari, Kaveh Gharaei Nejad
Pemphigus vulgaris is a chronic autoimmune disease and glucocorticoids are one of the main treatments. Our study investigates the prevalence and associated factors of glucocorticoid-induced diabetes mellitus in these patients under different glucocorticoid regimens. 36 patients with first diagnosed Pemphigus vulgaris based on pathological and direct immunofluorescence findings who had received different glucocorticoid regimens (1-2 mg/kg oral or 1-2 mg/kg oral with 1g methylprednisolone pulse daily for 3 consecutive days with or without azathioprine) were evaluated during 2014-2016...
June 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/28836075/antitumor-evaluation-and-3d-qsar-studies-of-a-new-series-of-the-spiropyrroloquinoline-isoindolinone-aza-isoindolinone-derivatives-by-comparative-molecular-field-analysis-comfa
#19
Masoud Sadeghzadeh, Maryam Salahinejad, Nahid Zarezadeh, Mehdi Ghandi, Maryam Keshavarz Baghery
In current study, antitumor activity of two series of the newly synthesized spiropyrroloquinoline isoindolinone and spiropyrroloquinoline aza-isoindolinone scaffolds was evaluated against three human breast normal and cancer cell lines (MCF-10A, MCF-7 and SK-BR-3) and compared with cytotoxicity values of doxorubicin and colchicine as the standard drugs. It was found that several compounds were endowed with cytotoxicity in the low micromolar range. Among these two series, compounds 6i, 6j, 6k and 7l, 7m, 7n, 7o containing 3-ethyl-1H-indole moiety were found to be highly effective against both cancer cell lines ranging from [Formula: see text] to [Formula: see text] in comparison with the corresponding analogs...
August 23, 2017: Molecular Diversity
https://www.readbyqxmd.com/read/28834384/association-of-s100-calcium-binding-protein-a12-receptor-for-advanced-glycation-endproducts-and-nuclear-factor-%C3%AE%C2%BAb-expression-with-inflammation-in-pulp-tissues-from-tooth-caries
#20
Mohammad M Y Khorasani, Pouria Andam-Shahsavari, Nahid Zainodini, Hossein Khoramdelazad, Reza Nosratabadi
AIM: S100 calcium-binding protein A1 (S100A12) is a pro-inflammatory molecule which is secreted during inflammation and induces chemotaxis and the production of pro-inflammatory cytokines via interaction with receptor for advanced glycation endproducts (RAGE) and subsequent, activation of nuclear factor-κB (NF-κB). The present study was designed to determine the expression levels of S100A12, RAGE, and NF-κB in the inflamed pulp of carried teeth. METHODS: In the present study, mRNA from 50 inflamed pulp and 50 healthy pulp were used for expression studies using real-time polymerase chain reaction...
August 20, 2017: Journal of Investigative and Clinical Dentistry
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