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https://www.readbyqxmd.com/read/28345729/medication-adherence-among-cardiac-patients-in-khartoum-state-sudan-a-cross-sectional-study
#1
Abdelmoneim Awad, Nahid Osman, Siham Altayib
INTRODUCTION: Non-adherence to medication among cardiac patients is often the major risk factor for poor clinical outcomes, increased mortality rates and higher healthcare costs. The literature evaluating the prevalence of and reasons for non-adherence in resource-poor settings is extremely limited compared to resource-rich settings. There is a scarcity of data about medication adherence in Sudan hence this study was performed to identify prevalence, predictors and barriers of non-adherence to medication among cardiac patients in Khartoum State...
March 23, 2017: Cardiovascular Journal of Africa
https://www.readbyqxmd.com/read/28345331/cervical-cancer-screening-in-iranian-women-healthcare-practitioner-perceptions-and-views
#2
Mansoureh Refaei, Nahid Dehghan Nayeri, Zohreh Khakbazan, Minoo Pakgohar
Background: Although regular screening for cervical cancer with the Papanicolaou test is an important element for reducing the incidence and mortality of cervical cancer, the actual screening program in Iranian women is not sufficiently comprehensive at present. The purpose of this study was to explore healthcare provider perceptions of factors affecting cervical cancer screening in Iranian women. Methods: In this qualitative study performed from September 2015 to August 2016 in Hamadan, Iran, we conducted semi-structured in depth interviews with 14 healthcare providers selected purposefully...
February 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28344011/the-epidemiology-pathogenesis-transmission-diagnosis-and-management-of-multidrug-resistant-extensively-drug-resistant-and-incurable-tuberculosis
#3
REVIEW
Keertan Dheda, Tawanda Gumbo, Gary Maartens, Kelly E Dooley, Ruth McNerney, Megan Murray, Jennifer Furin, Edward A Nardell, Leslie London, Erica Lessem, Grant Theron, Paul van Helden, Stefan Niemann, Matthias Merker, David Dowdy, Annelies Van Rie, Gilman K H Siu, Jotam G Pasipanodya, Camilla Rodrigues, Taane G Clark, Frik A Sirgel, Aliasgar Esmail, Hsien-Ho Lin, Sachin R Atre, H Simon Schaaf, Kwok Chiu Chang, Christoph Lange, Payam Nahid, Zarir F Udwadia, C Robert Horsburgh, Gavin J Churchyard, Dick Menzies, Anneke C Hesseling, Eric Nuermberger, Helen McIlleron, Kevin P Fennelly, Eric Goemaere, Ernesto Jaramillo, Marcus Low, Carolina Morán Jara, Nesri Padayatchi, Robin M Warren
Global tuberculosis incidence has declined marginally over the past decade, and tuberculosis remains out of control in several parts of the world including Africa and Asia. Although tuberculosis control has been effective in some regions of the world, these gains are threatened by the increasing burden of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis. XDR tuberculosis has evolved in several tuberculosis-endemic countries to drug-incurable or programmatically incurable tuberculosis (totally drug-resistant tuberculosis)...
March 15, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28341597/effect-of-isopropyl-myristate-on-transdermal-permeation-of-testosterone-from-carbopol-gel
#4
Ahmed S Zidan, Nahid Kamal, Alaadin Alayoubi, Mark Seggel, Sarah Ibrahim, Ziyaur Rahman, Celia Cruz, Muhammad Ashraf
The objective of the current study was to investigate the effect of isopropyl myristate (IPM) on the in vitro permeation of Testosterone through human cadaver skin from carbopol- gels. Six Testosterone gel formulations were prepared employing different IPM contents of 0, 0.4, 0.7, 1, 2 and 3%. The gels were characterized for drug permeation, matrix morphology, pH, kinetics of ethanol evaporation and viscosity. Mass balance studies were performed to estimate testosterone distribution among the compartments of diffusion cells...
March 21, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28333949/metabolic-syndrome-and-its-components-among-rheumatoid-arthritis-patients-a-comprehensive-updated-systematic-review-and-meta-analysis
#5
Jamal Hallajzadeh, Saeid Safiri, Mohammad Ali Mansournia, Maliheh Khoramdad, Neda Izadi, Amir Almasi-Hashiani, Reza Pakzad, Erfan Ayubi, Mark J M Sullman, Nahid Karamzad
BACKGROUND: Estimating the current global prevalence of metabolic syndrome (MetS), and its components, among rheumatoid arthritis (RA) patients is necessary in order to formulate preventative strategies and to ensure there are adequate community resources available for these patients. Furthermore, the association between RA and MetS is controversial and has not previously been comprehensively assessed. Therefore, the present study aimed to: 1) determine the prevalence of MetS, and its components, among RA patients across the world 2) update the odds ratio of MetS in RA patients, compared to healthy controls, using a comprehensive systematic review and meta-analysis...
2017: PloS One
https://www.readbyqxmd.com/read/28331501/is-emotion-recognition-related-to-core-symptoms-of-childhood-adhd
#6
Mehdi Tehrani-Doost, Gholamreza Noorazar, Zahra Shahrivar, Anahita Khorrami Banaraki, Parvane Farhad Beigi, Nahid Noorian
OBJECTIVE: Children with attention deficit/hyperactivity disorder (ADHD) have some problems in social relationships which may be related to their deficit in recognizing emotional expressions. It is not clear if the deficit in emotion recognition is secondary to core symptoms of ADHD or can be considered as an independent symptom. This study aimed to evaluate the ability of detecting emotional faces and its relation to inattention and hyperactivity-impulsivity in children with ADHD compared to a typically developing (TD) group...
2017: Journal of the Canadian Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28329598/successful-treatment-of-melkersson-rosenthal-syndrome-with-dapsone-a-case-report-and-review-of-the-literature
#7
Nazan Emiroglu, Ozlem Su, Fatma Pelin Cengiz, Nahide Onsun
Melkersson-Rosenthal syndrome (MRS) is a rare disease characterized by a triad of relapsing or persistent orofacial edema, recurrent lower motor neuron facial nerve palsy and fissured tongue. Acute, painless, non-erythematosus orofacial edema is observed in all patients. We report a case of a 13-year-old girl who presented with a 2-year history of swelling of the upper lip, facial paralysis, and fissured tongue; she was treated successfully with dapsone.
October 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28329484/gabapentin-induced-aquagenic-wrinkling-of-the-palms
#8
Nazan Emiroglu, Fatma P Cengiz, Ozlem Su, Nahide Onsun
Aquagenic keratoderma (AK) or aquagenic wrinklingis a rare palmoplantar skin disease. It is sporadic orhereditary condition. It appears in childhood or youngadulthood and it is seen as multiple asymptomaticsmall shiny papules on the peripheral margin ofpalms and/or soles after submersion in water. Thepathogenesis and etiology of ASA remains unclear.Drugs sometimes trigger AK. Herein, we present thecase of a 29-year-old man who had begun treatmentwith gabapentin three weeks before the onset of hiscutaneous symptoms...
January 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28326292/acne-located-on-the-trunk-whey-protein-supplementation-is-there-any-association
#9
Fatma Pelin Cengiz, Bengu Cevirgen Cemil, Nazan Emiroglu, Anil Gulsel Bahali, Nahide Onsun
Whey protein is a source of protein that was isolated from milk. Whey proteins are composed of higher levels of essential amino acids. The role of diet in acne etiology has been investigated for several years. It was established that milk and milk products can trigger acneiform lesions, and recent evidence supports the role of whey protein supplements in acne. Herein, we report 6 healthy male adolescent patients developing acne located only to the trunk after the consumption of whey protein supplements for faster bodybuilding...
2017: Health Promotion Perspectives
https://www.readbyqxmd.com/read/28318077/the-effectiveness-of-familiar-auditory-stimulus-on-hospitalized-neonates-physiologic-responses-to-procedural-pain
#10
Elham Azarmnejad, Forogh Sarhangi, Mahrooz Javadi, Nahid Rejeh, Susan Amirsalari, Seyed Davood Tadrisi
Hospitalized neonates usually undergo different painful procedures. This study sought to test the effects of a familiar auditory stimulus on the physiologic responses to pain of venipuncture among neonates in intensive care unit. The study design is quasi-experimental. The randomized clinical trial study was done on 60 full-term neonates admitted to the neonatal intensive care unit between March 20 to June 20, 2014. The neonates were conveniently selected and randomly allocated to the control and the experimental groups...
March 20, 2017: International Journal of Nursing Practice
https://www.readbyqxmd.com/read/28315317/an-effective-and-efficient-method-of-transfecting-primary-human-chondrocytes-in-suspension
#11
Mohammad Shahidul Makki, Nahid Akhtar, Tariq M Haqqi
Human chondrocytes accumulate an ECM-rich matrix by secreting matrix macromolecules during monolayer culture, which makes them difficult to transfect efficiently. Here we report a non-viral based protocol to transfect the primary human chondrocytes with high efficiency in suspension. Chondrocyte cultures were digested using Pronase and Collagenase and transfected in suspension. Transfection efficiencies of more than 80% were achieved routinely using the protocol described. The viability of siRNA transfected or un-transfected chondrocytes was not affected and resulted in 80-90% knockdown of the target mRNA levels...
March 14, 2017: Analytical Biochemistry
https://www.readbyqxmd.com/read/28299033/the-association-of-age-and-gender-with-risk-factors-of-noncommunicable-diseases-among-employees-in-west-of-iran
#12
Nahid Khademi, Mehran Babanejad, Atefeh Asadmobini, Hossein Karim
BACKGROUND: The relationships that age and gender share with risk factors (RFs) of noncommunicable diseases (NCDs) were assessed among a large-scale employ in Western Iran. METHODS: In this epidemiologic cross-sectional study, 7129 employees from Kermanshah Province were assessed using a census method in 2012. Data on RFs of NCD were collected using a standard questionnaire. Demographic information, diet, physical activity, tobacco use, and history of hypertension, history of diabetes, cardiovascular diseases, osteoporosis, and cancer were studied...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28292893/small-molecule-selectively-suppresses-myc-transcription-in-cancer-cells
#13
Claire Bouvard, Sang Min Lim, John Ludka, Nahid Yazdani, Ashley K Woods, Arnab K Chatterjee, Peter G Schultz, Shoutian Zhu
Stauprimide is a staurosporine analog that promotes embryonic stem cell (ESC) differentiation by inhibiting nuclear localization of the MYC transcription factor NME2, which in turn results in down-regulation of MYC transcription. Given the critical role the oncogene MYC plays in tumor initiation and maintenance, we explored the potential of stauprimide as an anticancer agent. Here we report that stauprimide suppresses MYC transcription in cancer cell lines derived from distinct tissues. Using renal cancer cells, we confirmed that stauprimide inhibits NME2 nuclear localization...
March 14, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28286069/the-risks-and-benefits-of-cavernosal-neurovascular-bundle-sparing-during-radical-prostatectomy-a-systematic-review-and-meta-analysis
#14
REVIEW
Laura N Nguyen, Linden Head, Kelsey Witiuk, Nahid Punjani, Ranjeeta Mallick, Sonya Cnossen, Dean A Fergusson, Ilias Cagiannos, Luke T Lavallée, Christopher Morash, Rodney H Breau
PURPOSE: Our objective was to summarize published data on associations between cavernosal neurovascular bundle preservation (nerve spare) and positive surgical margins, erectile function, urinary function, and other patient reported outcomes. MATERIALS AND METHODS: A systematic literature search of Medline, EMBASE, and Cochrane Reviews databases was performed for interventional or observational studies published between 2000-2014. English-language articles that compared clinical outcomes of patients undergoing nerve-sparing and non-nerve-sparing radical prostatectomy were included...
March 9, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28283107/sexual-dysfunction-levels-in-iranian-women-suffering-from-multiple-sclerosis
#15
Nahid Dehghan-Nayeri, Zohreh Khakbazan, Faezeh Ghafoori, Seyed Massood Nabavi
OBJECTIVE: Sexual dysfunction (SD) is a common complaint in women who suffer from Multiple Sclerosis (MS), which has been categorized in three levels (primary, secondary, and tertiary) in previous studies. This study was conducted to assess the prevalence of sexual dysfunction (SD) at each level, and to identify associated factors and their impacts on SD in married women who suffer from Multiple Sclerosis. This study was conducted in Iran where the cultural barriers are recognized as important challenges in sexual function...
February 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/28282800/fbln-4-and-bcrp-genes-as-two-prognostic-markers-are-downregulated-in-breast-cancer-tissue
#16
Jamshid Motalebzadeh, Frouzandeh Mahjoubi, Nahid Nafissi, Maria Hashemian, Mohsen Taheri, Younes Hosseinpour
BACKGROUND: Fibulin-4 (FBLN-4) is an extracellular glycoprotein that is upregulated in some cancer and is khown as prognostic marker in ovarian and cervical cancer. Breast cancer resistance protein (BCRP) is an ATP-binding cassette transporter that facilitates the efflux of various anticancer drugs from the cell and cause MDR phenotype in breast tumors. Many studies are available that indicat overexpression of BCRP gene in breast cancer. OBJECTIVE: In the present study we aimed to analyze the expression level of FBLN-4 and BCRP in Iranian breast cancer patients...
March 3, 2017: Cancer Biomarkers: Section A of Disease Markers
https://www.readbyqxmd.com/read/28280798/endometrial-expression-of-%C3%AE-3-integrin-calcitonin-and-plexin-b1-in-the-window-of-implantation-in-women-with-unexplained-infertility
#17
Mehran Dorostghoal, Hamid-O-Allah Ghaffari, Nahid Shahbazian, Maryam Mirani
BACKGROUND: Endometrial receptivity plays a key role in the establishment of successful implantation and its impairment may contribute to subfertility and limit the assisted reproduction techniques (ART) success. OBJECTIVE: The aim of present study was to investigate endometrial receptivity in terms of β3 integrin, calcitonin and plexin-B1 expression in women with unexplained infertility. MATERIALS AND METHODS: We evaluated expression of β3 integrin, calcitonin and plexin-B1 through mRNA level measurement with real-time RT-PCR, in the endometrium of 16 infertile women with unexplained infertility and 10 fertile women...
January 2017: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/28274046/can-salivary-acetylcholinesterase-be-a-diagnostic-biomarker-for-alzheimer
#18
Sedigheh Bakhtiari, Nahid Beladi Moghadam, Marjan Ehsani, Hamed Mortazavi, Siamak Sabour, Mahin Bakhshi
INTRODUCTION: The loss of brain cholinergic activity is a key phenomenon in the biochemistry of Alzheimer's Disease (AD). Due to the specific biosynthesis of Acetylcholinesterase (AChE) of cholinergic neurons, the enzyme has been proposed as a potential biochemical marker of cholinergic activity. AChE is expressed not only in the Central Nervous System (CNS), Peripheral Nervous System (PNS) and muscles, but also on the surface of blood cells and saliva. AIM: This study aimed to measure salivary AChE activity in AD and to determine the feasibility of creating a simple laboratory test for diagnosing such patients...
January 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28254508/patterns-of-age-related-changes-for-phosphodiesterase-type-10a-in-comparison-with-dopamine-d2-3-receptors-and-sub-cortical-volumes-in-the-human-basal-ganglia-a-pet-study-with-18-f-mni-659-and-11-c-raclopride-with-correction-for-partial-volume-effect
#19
Patrik Fazio, Martin Schain, Ladislav Mrzljak, Nahid Amini, Sangram Nag, Nabil Al-Tawil, Cheryl J Fitzer-Attas, Juliana Bronzova, Bernhard Landwehrmeyer, Cristina Sampaio, Christer Halldin, Andrea Varrone
Phosphodiesterase 10A enzyme (PDE10A) is an important striatal target that has been shown to be affected in patients with neurodegenerative disorders, particularly Huntington´s disease (HD). PDE10A is expressed on striatal neurones in basal ganglia where other known molecular targets are enriched such as dopamine D2/3 receptors (D2/3 R). The aim of this study was to examine the availability of PDE10A enzyme in relation with age and gender and to compare those changes with those related to D2/3 R and volumes in different regions of the basal ganglia...
February 28, 2017: NeuroImage
https://www.readbyqxmd.com/read/28249912/prognostic-evaluation-of-neutrophil-lymphocyte-ratio-in-patients-with-mycosis-fungoides
#20
Fatma Pelin Cengiz, Nazan Emiroglu, Dilek Biyik Ozkaya, Anil Gulsel Bahali, Ozlem Su, Nahide Onsun
BACKGROUND: The role of inflammation has been established in cancer biology and the neutrophil to lymphocyte ratio postulated as a marker of systemic inflammatory response. The prognostic significance of neutrophil to lymphocyte ratio has never been explored in patients with mycosis fungoides. METHODS: Data from 119 mycosis fungoides (MF) patients, diagnosed between 1998 and 2015 at a single centre, were evaluated retrospectively. The prognostic influence of the neutrophil to lymphocyte ratio and other clinico-pathological factors including age, lactate dehydrogenase, stage of disease, beta-2-microglobulin levels, and total IgE levels were evaluated...
January 2017: Annals of Clinical and Laboratory Science
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