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https://www.readbyqxmd.com/read/28735818/curcuminoids-modify-lipid-profile-in-type-2-diabetes-mellitus-a-randomized-controlled-trial
#1
Yunes Panahi, Nahid Khalili, Ebrahim Sahebi, Soha Namazi, Željko Reiner, Muhammed Majeed, Amirhossein Sahbekar
BACKGROUND: Type 2 diabetes (T2D) is an established risk factor for cardiovascular disease (CVD) and is associated with disturbed metabolism of lipids and lipoproteins. Curcuminoids are natural products with anti-diabetic and lipid-modifying actions but their efficacy in improving dyslipidemia in diabetic individuals has not been sufficiently studied. OBJECTIVE: To investigate the efficacy of supplementation with curcuminoids, plus piperine as an absorption enhancer, in improving serum lipids in patients with T2D...
August 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28735143/transcranial-low-level-laser-therapy-improves-brain-mitochondrial-function-and-cognitive-impairment-in-d-galactose-induced-aging-mice
#2
Farzad Salehpour, Nahid Ahmadian, Seyed Hossein Rasta, Mehdi Farhoudi, Pouran Karimi, Saeed Sadigh-Eteghad
Mitochondrial function plays a key role in the aging-related cognitive impairment, and photoneuromodulation of mitochondria by transcranial low-level laser therapy (LLLT) may contribute to its improvement. This study focused on the transcranial LLLT effects on the D-galactose (DG)-induced mitochondrial dysfunction, apoptosis, and cognitive impairment in mice. For this purpose, red and near-infrared (NIR) laser wavelengths (660 and 810 nm) at 2 different fluencies (4 and 8 J/cm(2)) at 10-Hz pulsed wave mode were administrated transcranially 3 d/wk in DG-received (500 mg/kg/subcutaneous) mice model of aging for 6 weeks...
July 6, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/28729223/synthesis-characterization-and-antimicrobial-study-of-polymeric-transition-metal-complexes-of-mn-ii-co-ii-ni-ii-cu-ii-and-zn-ii
#3
Shamim Ahmad Khan, Shahab A A Nami, Shahnawaz Ahmad Bhat, Abdul Kareem, Nahid Nishat
Salen ligands comprising of o-phenylenediamine (salop) and p-phenylenediamine (salpp) have been synthesized. The salen ligand, salop undergo Schiff base reaction with Formaldehyde and Barbituric acid to generate novel polymeric Schiff base, SBOPA in one instance while the second salen ligand, salpp on Schiff base reaction with formaldehyde and piperazine gives another novel polymeric Schiff base, SBPBA. These polymeric Schiff base ligands, SBOPA and SBPBA generates polymeric metal complexes in high yields on reaction with transition metal acetates, M(CH3COO)2...
July 17, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28724629/abrogation-of-heat-shock-factor-1-hsf1-phosphorylation-deregulates-its-activity-and-lowers-activation-threshold-leading-to-obesity-in-mice
#4
Xiongjie Jin, Aijun Qiao, Demetrius Moskophidis, Nahid F Mivechi
Heat shock factor 1 (Hsf1) is transcriptionally activated following exposure of mammalian cells to environmental insults and pathological conditions. The function of Hsf1 as a protector of cells and organisms towards a range of stress stimuli has been well-documented. However, how different Hsf1 post-transcriptional modifications affect its function in vivo is not understood. Hsf1 transcriptional activity is in part regulated by phosphorylation. Hsf1 phosphorylation of amino acid residues at S303 and S307 has been shown to repress Hsf1 transcriptional activity under normal physiological growth conditions...
July 19, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28713517/developing-the-concept-of-caring-in-nursing-education
#5
Maryam Salehian, Abbas Heydari, Hossein Karimi Moonaghi, Nahid Aghebati
BACKGROUND: Caring is a value-based concept in the nursing field and in education. Exact understanding of caring in education and developing this concept in nursing will result in the evolution of the position of nursing science and profession. AIM: The aim of this study was to attempt to develop the concept of caring in nursing education. METHODS: This qualitative study was conducted in 2016 using directed content analysis. Participants were thirteen subjects (6 instructors and 7 senior and junior nursing students) who were selected using purposeful sampling method...
May 2017: Electronic Physician
https://www.readbyqxmd.com/read/28712980/association-of-selective-serotonin-reuptake-inhibitors-and-bone-mineral-density-in-elderly-women
#6
Smita Saraykar, Vineeth John, Bo Cao, Matthew Hnatow, Catherine G Ambrose, Nahid Rianon
Depression and osteoporosis are 2 common comorbidities in geriatric patients. There are concerns about the deleterious effects of selective serotonin reuptake inhibitor (SSRI) antidepressant use on bone mineral density (BMD). We examined the association between SSRI use and BMD in elderly women (≥65 yr) referred to a geriatric osteoporosis clinic for bone health evaluation. Cross-sectional analyses using the general linear model were performed on data collected retrospectively from August 2010 to April 2015...
July 13, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28710505/application-of-human-acellular-breast-dermal-matrix-abdm-in-implant-based-breast-reconstruction-an-experimental-study
#7
Nahid Nafisi, Mohammad Esmaeil Akbari, Fatemeh Mahjoub, Mohammad Javad Mohseni, Shabnam Sabetkish, Reza Khorramirouz, Mona Tehrani, Abdol-Mohammad Kajbafzadeh
BACKGROUND: The use of acellular dermal matrices (ABDM) has become more common for breast reconstruction to improve postoperative outcomes. We evaluated the efficacy of breast reconstruction by the application of human ABDM in a sheep model. METHODS: The sheep in group I (GI) (N = 4) underwent the following procedures on the right side: (1) breast reconstruction using human ABDM after total mastectomy, (2) human ABDM under the skin, near the breast area and on the left side, (3) fat injection and human ABDM after partial mastectomy, and (4) replacement of ABDM in the abdominal wall far from the breast...
July 14, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28710371/lattice-thermal-conductivity-of-mgsio3-perovskite-from-first-principles
#8
Nahid Ghaderi, Dong-Bo Zhang, Huai Zhang, Jiawei Xian, Renata M Wentzcovitch, Tao Sun
We investigate lattice thermal conductivity κ of MgSiO3 perovskite (pv) by ab initio lattice dynamics calculations combined with exact solution of linearized phonon Boltzmann equation. At room temperature, κ of pristine MgSiO3 pv is found to be 10.7 W/(m · K) at 0 GPa. It increases linearly with pressure and reaches 59.2 W/(m · K) at 100 GPa. These values are close to multi-anvil press measurements whereas about twice as large as those from diamond anvil cell experiments. The increase of k with pressure is attributed to the squeeze of weighted phase-spaces phonons get emitted or absorbed...
July 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28708432/epigenetic-changes-of-the-esr1-gene-in-breast-tissue-of-healthy-women-a-missing-link-with-breast-cancer-risk-factors
#9
Abdolreza Daraei, Pantea Izadi, Ghasemali Khorasani, Nahid Nafissi, Mohammad Mehdi Naghizadeh, Nasim Younosi, Alipasha Meysamie, Yaser Mansoori, Milad Bastami, Javad Tavakkoly-Bazzaz
BACKGROUND: Reproductive history and obesity are among the well-recognized risk factors in the development of breast cancer, which are partially mediated by the increased exposure of breast tissues to estrogens. However, only a few studies have investigated the link between these risk factors and the pattern of methylation signatures in the breast tissue of healthy women. The role of estrogen receptor 1 (ESR1) gene hypermethylation is reportedly important in the development of breast cancer...
July 14, 2017: Genetic Testing and Molecular Biomarkers
https://www.readbyqxmd.com/read/28706548/the-effect-of-continuous-care-on-the-lifestyle-of-patients-with-multiple-sclerosis-a-randomized-clinical-trial
#10
Masoud Khodaveisi, Fatemah Ashtarani, Ali Beikmoradi, Nahid Mohammadi, Hossein Mahjub, Mehrdokht Mazdeh, Elham Ashtarani
BACKGROUND: Multiple sclerosis is a common debilitating chronic disease of the central nervous system with a progressive and prolonged nature. Patients need an adjusted lifestyle and continuous care in order to prevent its recurrence and progressive disabilities. This study aimed to assess the effect of continuous care on lifestyle in patients suffering from multiple sclerosis. MATERIALS AND METHODS: A randomized clinical trial was conducted among 72 patients with multiple sclerosis who referred to the Farshchian Educational Hospital in Hamadan, Iran in 2013...
May 2017: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/28706542/effect-of-fordyce-s-happiness-program-on-stress-anxiety-and-depression-among-the-patients-undergoing-hemodialysis
#11
Younes Mehrabi, Zahra Ghazavi, Nahid Shahgholian
BACKGROUND: Patients with end-stage renal disease on hemodialysis are affected by psychological stressors, which contribute to poor quality of life and negative clinical outcomes. Stress, anxiety, and depression are highly prevalent in this population. Fordyce's happiness program has been believed to be one of the complementary therapies that could promote psychological wellbeing. The goal of this study was to evaluate the effects of Fordyce's happiness program on the stress, anxiety, and depression in patients with hemodialysis...
May 2017: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/28702113/cost-effectiveness-analysis-of-the-unfractionated-heparin-versus-low-molecular-weight-heparin-in-hospitalized-patients-with-stroke-due-to-atrial-fibrillation-in-shiraz-south-of-iran
#12
Nahid Hatam, Jamshid Bahmei, Khosro Keshavarz, Farnia Feiz, Reihaneh Sedghi, Afshin Borhani-Haghighi
BACKGROUND: Patients with atrial fibrillation (AF) make a unique group of strokes. Unfractionated heparin (UFH) and low-molecular-weight heparin (LMWH) are among the medications used for preventing blood coagulation. This study was carried out aiming at analyzing the cost effectiveness of LMWH versus UFH in hospitalized patients with stroke due to AF with respect to the Iranian population. METHODS: This randomized study was an economic evaluation of cost effectiveness with the help of the cross-sectional data of 2013-2015...
June 2017: Journal of Vascular and Interventional Neurology
https://www.readbyqxmd.com/read/28701046/a-review-of-the-antioxidant-activity-of-celery-apium-graveolens-l
#13
Wesam Kooti, Nahid Daraei
Plants are an important source of natural active products that are different, based on mechanism and biological properties. Celery ( Apium graveolens L) is a plant from the apiaceae family and phenolic and antioxidant compounds of this plant have been studied by several scientists. The aim of this study was to review systematically the antioxidant activity of celery. Required articles were searched from databases such as Science Direct, PubMed, Scopus, and Springer. Keywords used in this study were Apium graveolens L, celery, antioxidant, free radical, leaf, and seed...
January 1, 2017: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/28698886/the-prevalence-subtypes-and-obstetric-risk-factors-of-urinary-incontinence-in-reproductive-age-women-referred-to-community-health-care-centers-of-dezful-iran-2015
#14
Roghaye Komeilifar, Nahid Javadifar, Poorandokht Afshari, Mohammad Hosein Haghighizade, Azam Honarmandpour
BACKGROUND: Urinary incontinence (UI) is a common health problem and has a profound effect on the quality of life and psychosocial aspects of the affected women. The aim of this study was to investigate the prevalence and risk factors of UI in reproductive age women. METHODS: This cross-sectional study was conducted on 2000 reproductive age women from February to June 2015. The women were selected from all of the primary health care centers of Dezful, using easy access sampling method...
July 2017: International Journal of Community Based Nursing and Midwifery
https://www.readbyqxmd.com/read/28697415/a-high-area-porous-and-resistant-platinized-stainless-steel-fiber-coated-by-nanostructured-polypyrrole-for-direct-hs-spme-of-nicotine-in-biological-samples-prior-to-gc-fid-quantification
#15
Sana Abdolhosseini, Alireza Ghiasvand, Nahid Heidari
The surface of a stainless steel fiber was made porous, resistant and cohesive using electrophoretic deposition and coated by the nanostructured polypyrrole using an amended in-situ electropolymerization method. The coated fiber was applied for direct extraction of nicotine in biological samples through a headspace solid-phase microextraction (HS-SPME) method followed by GC-FID determination. The effects of the important experimental variables on the efficiency of the developed HS-SPME-GC-FID method, including pH of sample solution, extraction temperature and time, stirring rate, and ionic strength were evaluated and optimized...
June 27, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28693648/optimal-doses-of-egf-and-gdnf-act-as-biological-response-modifiers-to-improve-porcine-oocyte-maturation-and-quality
#16
Mehdi Vafaye Valleh, Nahid Karimi Zandi, Mikkel Aabech Rasmussen, Poul Hyttel
It is well documented that both epidermal growth factor (EGF) and glial cell line-derived neurotrophic factor (GDNF) are critical for porcine oocyte maturation, however, little information is known about their mechanism of action in vitro. To gain insight into the mechanisms of action of the optimum doses of EGF and GDNF on porcine oocyte maturation, porcine cumulus-oocyte complexes (COCs) were matured in defined porcine oocyte medium supplemented with EGF, GDNF or a combination of both at varying concentrations (0-100 ng/ml) for 44 h...
July 11, 2017: Zygote: the Biology of Gametes and Early Embryos
https://www.readbyqxmd.com/read/28682306/unique-roles-for-histone-h3k9me-states-in-rnai-and-heritable-silencing-of-transcription
#17
Gloria Jih, Nahid Iglesias, Mark A Currie, Natarajan V Bhanu, Joao A Paulo, Steven P Gygi, Benjamin A Garcia, Danesh Moazed
Heterochromatic DNA domains play important roles in regulation of gene expression and maintenance of genome stability by silencing repetitive DNA elements and transposons. From fission yeast to mammals, heterochromatin assembly at DNA repeats involves the activity of small noncoding RNAs (sRNAs) associated with the RNA interference (RNAi) pathway(1-9). Typically, sRNAs, originating from long noncoding RNAs, guide Argonaute-containing effector complexes to complementary nascent RNAs to initiate histone H3 lysine 9 di- and tri-methylation (H3K9me2 and H3K9me3, respectively) and heterochromatin formation(10-17)...
June 22, 2017: Nature
https://www.readbyqxmd.com/read/28670673/in-vitro-application-of-pentoxifylline-preserved-ultrastructure-of-spermatozoa-after-vitrification-in-asthenozoospermic-patients
#18
Ali Nabi, Mohammad Ali Khalili, Ali Reza Talebi, Esmat Mangoli, Nahid Yari, Stefania Annarita Nottola, Selenia Miglietta, Fatemeh Taheri
PURPOSE: To evaluate the effect of in vitro application of pentoxifylline (PX) on sperm parameters and ultrastructure after vitrification in asthenozoospermic patients. MATERIALS AND METHODS: A total of 30 asthenozoospermic semen samples (aged 25-45 years) were divided into four groups before vitrification, after vitrification, control (without PX) and experimental (with PX). In experimental group, each sample was exposed for 30 min to 3.6mmol/l PX and the control group without any treatment apposing in 370C for 30 min...
July 2, 2017: Urology Journal
https://www.readbyqxmd.com/read/28670584/living-with-hypertension-a-qualitative-research
#19
Afzal Shamsi, Nahid Dehghan Nayeri, Maryam Esmaeili
BACKGROUND: Hypertension affects many aspects of the patients' life. Factors such as attitudes, beliefs and experiences, and social and cultural conditions of patients have effective roles in hypertension treatment process. The aim of this research was to explore perspectives and experiences of patients with hypertension while living with this disease. METHODS: This is a qualitative research using content analysis approach. 27 hypertensive patients who referred to hospitals affiliated to Tehran University of Medical Sciences were selected based on purposive sampling, and semi-structured interviews were carried out...
July 2017: International Journal of Community Based Nursing and Midwifery
https://www.readbyqxmd.com/read/28670250/the-relationship-between-severity-of-disease-and-vitamin-d-levels-in-children-with-atopic-dermatitis
#20
Ozlem Su, Anıl Gülsel Bahalı, Ayşegül Doğan Demir, Dilek Bıyık Ozkaya, Selçuk Uzuner, Didem Dizman, Nahide Onsun
INTRODUCTION: Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disorder. Vitamin D is a liposoluble vitamin synthesized mainly in the skin. Vitamin D has several effects on the skin. AIM: To assess the serum level of vitamin D in children with AD and determine its relation to AD severity. MATERIAL AND METHODS: Sixty patients with AD were enrolled in the study. We evaluated disease severity using the SCORing Atopic Dermatitis (SCORAD) index...
June 2017: Postȩpy Dermatologii i Alergologii
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