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A Y Finlay, M S Salek, D Abeni, L Tomás Aragonés, O D van Cranenburgh, A W M Evers, G Jemec, D Linder, L Manolache, S E Marrón, C A C Prinsen, P Susitaival, P Chernyshov
The aim of this study was to describe the many ways in which quality of life (QoL) measurement may potentially be advantageous in routine clinical dermatology practice. Thirteen members of the EADV Task Force on Quality of Life, eight dermatologists, three health psychologists, one epidemiologist and one pharmacoepidemiologist, independently listed all of the ways they thought this may be advantageous. 108 different way of using QoL information in clinical practice were suggested (median per participant=8, range=4-15), and were classified into 20 descriptive groups...
September 29, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
Manuel Pedro Pereira, Sonja Ständer
Chronic pruritus is a complex multifactorial symptom associated with many different diseases that represents a diagnostic and therapeutic challenge for physicians. In order to better manage chronic pruritus, a detailed medical history, individualized diagnostic procedures and treatment approaches are necessary. Treatment should not only take itch into consideration, but also scratching-induced skin lesions and accompanying disorders such as anxiety, depression and insomnia. Various standardized questionnaires and scales have been developed to assist in the characterization and assessment of these parameters...
September 12, 2016: Allergology International: Official Journal of the Japanese Society of Allergology
R N Werner, A F Nikkels, B Marinović, M Schäfer, M Czarnecka-Operacz, A M Agius, Z Bata-Csörgő, J Breuer, G Girolomoni, G E Gross, S Langan, R Lapid-Gortzak, T H Lesser, U Pleyer, J Sellner, G M Verjans, P Wutzler, C Dressler, R Erdmann, S Rosumeck, A Nast
BACKGROUND: Herpes zoster (HZ, shingles) is a frequent medical condition which may severely impact the quality of life of affected patients. Different therapeutic approaches to treat acute HZ are available. OBJECTIVE: The aim of this European project was the elaboration of a consensus-based guideline on the management of patients who present with HZ, considering different patient populations and different localisations. This interdisciplinary guideline aims at an improvement of the outcomes of the acute HZ management concerning disease duration, acute pain and quality of life of the affected patients and at a reduction of the incidence of PHN and other complications...
August 31, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
A H Enk, E N Hadaschik, R Eming, G Fierlbeck, L E French, G Girolomoni, M Hertl, S Jolles, S Karpati, K Steinbrink, G Stingl, B Volc-Platzer, D Zillikens
BACKGROUND: The treatment of severe dermatological autoimmune diseases and toxic epidermal necrolysis (TEN) with high-dose intravenous immunoglobulin (IVIg) is a well-established procedure in dermatology. As treatment with IVIg is usually considered for rare clinical entities or severe clinical cases, the use of immunoglobulin is not generally based on data from randomized controlled trials that are usually required for the practice of evidence-based medicine. Owing to the rarity of the indications for the use of IVIg, it is also unlikely that such studies will be available in the foreseeable future...
July 13, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
A Wollenberg, A Oranje, M Deleuran, D Simon, Z Szalai, B Kunz, A Svensson, S Barbarot, L von Kobyletzki, A Taieb, M de Bruin-Weller, T Werfel, M Trzeciak, C Vestergard, J Ring, U Darsow
Atopic dermatitis (AD) is a clinically defined, highly pruritic, chronic inflammatory skin disease of children and adults. The diagnosis is made using evaluated clinical criteria. Disease activity is best measured with a composite score assessing both objective signs and subjective symptoms, such as SCORAD. The management of AD must consider the clinical and pathogenic variabilities of the disease and also target flare prevention. Basic therapy includes hydrating topical treatment, as well as avoidance of specific and unspecific provocation factors...
May 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
A Nast, A Jacobs, S Rosumeck, R N Werner
No abstract text is available yet for this article.
December 2015: Journal of the European Academy of Dermatology and Venereology: JEADV
S Ständer, C Zeidler, C Riepe, S Steinke, F Fritz, P Bruland, I Soto-Rey, M Storck, T Agner, M Augustin, C Blome, F Dalgard, A W M Evers, S Garcovich, M Gonçalo, J Lambert, F J Legat, T Leslie, L Misery, U Raap, A Reich, E Şavk, M Streit, E Serra-Baldrich, J Szepietowski, J Wallengren, E Weisshaar, M Dugas
BACKGROUND: Chronic pruritus is a frequently occurring symptom of various dermatoses that causes a high burden and impaired quality of life. An effective anti pruritic therapy is important for the patient, but its effectiveness is difficult to evaluate. Diverse methods and interpretations of pruritic metrics are utilized in clinical trials and the daily clinical practice in different countries, resulting in difficulties comparing collected data. METHODS: We founded a European Network on Assessment of Severity and Burden of Pruritus (PruNet) that is supported by the EADV...
July 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
Carla Giles, Thiru Vanniasinkam, Mary Barton, Timothy J Mahony
Equine adenovirus 2 (EAdV-2) is one of two serotypes of adenoviruses known to infect equines. Initial studies did not associate EAdV-2 infections with any specific clinical syndromes, although more recent evidence suggests that EAdV-2 may be associated with clinical and subclinical gastrointestinal infections of foals and adults respectively. In contrast, Equine adenovirus 1 is well recognised as a pathogen associated with upper respiratory tract infections of horses. In this study the complete genome sequence of EAdV-2 is reported...
September 30, 2015: Veterinary Microbiology
P Chernyshov, J de Korte, L Tomas-Aragones, S Lewis-Jones
The impact of skin conditions in children can profoundly affect a variety of lifestyle parameters that may have important personal consequences. Several national guidelines for children with different skin conditions recommend health-related quality of life (HRQoL) measurement as part of the assessment process. HRQoL also plays an important role in educational programmes for children with chronic skin conditions and their parents. In this paper, the EADV Taskforce on Quality of life provides researchers and clinicians data on the achievements in this field, as well as the peculiarities of HRQoL assessment in children, and an overview of the most commonly used and validated generic, dermatology-specific and disease-specific instruments related to paediatric dermatology...
December 2015: Journal of the European Academy of Dermatology and Venereology: JEADV
D-M Zhang, M-M Ma, W-T Wen, X Zhu, L Xu, Z-J He, X He, J-H Wu, Y-W Hu, Y Zheng, Y Deng, C-J Lin, J-H Lu, M-F Li, K-Y Cao
To understand the clinical epidemiology and molecular characteristics of human bocavirus (HBoV) infection in children with diarrhoea in Guangzhou, South China, we collected 1128 faecal specimens from children with diarrhoea from July 2010 to December 2012. HBoV and five other major enteric viruses were examined using real-time polymerase chain reaction. Human rotavirus (HRV) was the most prevalent pathogen, detected in 250 (22·2%) cases, followed by enteric adenovirus (EADV) in 76 (6·7%) cases, human astrovirus (HAstV) in 38 (3·4%) cases, HBoV in 17 (1·5%) cases, sapovirus (SaV) in 14 (1·2%) cases, and norovirus (NoV) in 9 (0·8%) cases...
August 2015: Epidemiology and Infection
X Rabasseda
The 23rd Congress of the European Academy of Dermatology and Venereology started in Amsterdam with a day dedicated mostly to courses, during which electronic posters were also available. Scientists and researchers attending the conference had an opportunity for reviewing the latter investigations in dermatology through a series of computer terminals showing posters and allowing for e-mail discussions with the presenters. In a number of presentations, psoriasis was one of the major focuses of interest during EADV...
October 2014: Drugs of Today
Z Bai, H Xie, Q You, S Pickerill, Y Zhang, T Li, J Geng, L Hu, H Shan, B Di
UNLABELLED: Cross-priming amplification (CPA) was evaluated for the early detection of norovirus (NV), rotavirus A (RV-A), enteric adenovirus (EAdV) and astrovirus (AstV). The analytical sensitivity of the CPA assay was 10(3) copies ml(-1) for NV, RV-A and AstV detection and 10(4) copies ml(-1) for EAdV detection. For each of the four pathogens, the positive detection rate by CPA was similar to real-time PCR methods and higher than the rate observed in an ELISA. The detection coincidence rates of CPA and RT-PCR for NV, RV-A, EAdV and AstV were 98, 99, 99 and 100%, respectively...
March 2015: Letters in Applied Microbiology
M Hertl, H Jedlickova, S Karpati, B Marinovic, S Uzun, S Yayli, D Mimouni, L Borradori, C Feliciani, D Ioannides, P Joly, C Kowalewski, G Zambruno, D Zillikens, M F Jonkman
BACKGROUND: Pemphigus encompasses a group of life-threatening autoimmune bullous diseases characterized by blisters and erosions of the mucous membranes and skin. Before the era of immunosuppressive treatment, the prognosis of pemphigus was almost fatal. Due to its rarity, only few prospective controlled therapeutic trials are available. OBJECTIVES: For this reason, a group of European dermatologists with a long-standing interest and expertise in basic and clinical pemphigus research has sought to define diagnostic and therapeutic guidelines for the management of patients with pemphigus...
March 2015: Journal of the European Academy of Dermatology and Venereology: JEADV
Naohiro Kishida, Naohiro Noda, Eiji Haramoto, Mamoru Kawaharasaki, Michihiro Akiba, Yuji Sekiguchi
We describe an assay for simple and accurate quantification of human enteric adenoviruses (EAdVs) in water samples using a recently developed quantification method named microfluidic digital polymerase chain reaction (dPCR). The assay is based on automatic distribution of reaction mixture into a large number of nanolitre-volume reaction chambers and absolute copy number quantification from the number of chambers containing amplification products on the basis of Poisson statistics. This assay allows absolute quantification of target genes without the use of standard DNA...
2014: Water Science and Technology: a Journal of the International Association on Water Pollution Research
Wolf-Henning Boehncke, Brian Kirby, Diamant Thaci
The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) organized its second Fellows Symposium adjacent to the European Academy of Dermatology and Venereology (EADV) congress in Istanbul in October 2013. Wolf-Henning Boehncke from Geneva, Brian Kirby from Dublin, and Diamant Thaci from Lübeck formed the faculty. The 9 best-ranked abstracts submitted to this symposium were presented and discussed in detail. Five abstracts focused on comorbidities in patients with psoriasis or psoriatic arthritis; summaries of all abstracts are included herein...
June 2014: Journal of Rheumatology
Jae Kyung Kim, Jong Wan Kim
BACKGROUND: The enteric viruses have high health significance in humans, ranging from poliomyelitis, hepatitis, and gastroenteritis to innocuous infections, and the human enteric viral infection is the one of the most common diseases during early childhood. This study was conducted from July 2010 to October 2012. METHODS: We subjected 788 stool specimens using multiplex polymerase chain reaction (mPCR) tests that could simultaneously detect five enteric viruses, group A rotavirus (GAR), enteric adenovirus (EAdV), norovirus GI (NoV-GI), norovirus GII (NoV-GII), and human astrovirus (HAstV)...
January 2014: Journal of Clinical Laboratory Analysis
X Rabasseda
During the annual congress of the European Academy of Dermatology and Venereology (EADV), Istanbul, a bridge across Europe and Asia, attracted dermatologists from both continents, along with researchers and clinicians from the Americas and other parts of the world, to discuss new advancements in the treatment of common, in many cases severe, diseases that affect not only the skin, but also deep into human bodies. The following report reflects the important fact in dermatology that biologic and targeted therapies are conquering the drug armamentarium well beyond the known area of psoriasis and melanoma into areas such as atopic dermatitis...
October 2013: Drugs of Today
Wolf-Henning Boehncke, Brian Kirby
The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) organized a Fellows Symposium adjacent to the European Academy of Dermatology and Venerology (EADV) spring meeting in Verona, Italy, in 2012. Wolf-Henning Boehncke from Geneva and Brian Kirby from Dublin formed the faculty. Five papers were presented, followed by extended discussions among participants and faculty. Two contributions were on comorbidities of psoriasis patients and 2 on treatment of non-plaque-type psoriasis; the fifth presentation was a discussion of possible modes of action of vitamin D derivatives in the treatment of psoriasis...
August 2013: Journal of Rheumatology
Ulf Darsow, Andreas Wollenberg, Dagmar Simon, Alain Taïeb, Thomas Werfel, Arnold Oranje, Carlo Gelmetti, Ake Svensson, Mette Deleuran, Anne-Marie Calza, Francesca Giusti, Jann Lübbe, Stefania Seidenari, Johannes Ring
Difficult to control atopic dermatitis (AD) presents a therapeutic challenge and often requires combinations of topical and systemic treatment. Anti-inflammatory treatment of severe AD most commonly includes topical glucocorticosteroids and topical calcineurin antagonists used for exacerbation management and more recently for proactive therapy in selected cases. Topical corticosteroids remain the mainstay of therapy, the topical calcineurin inhibitors tacrolimus and pimecrolimus are preferred in certain locations...
2013: World Allergy Organization Journal
Alexander Nast, Ulrich Mrowietz, Knud Kragballe, Luis Puig, Kristian Reich, Richard B Warren, Jochen Schmitt
Guidelines can be developed on a national or multinational level. There are discussions concerning the relevance of different guidelines at different regional levels. Guidelines' evaluation can be approached by looking at the items "awareness", "agreement", "adoption" and "adherence". To assess the awareness of national and European (EDF/EADV) guidelines as a means of guidelines' evaluation. Online survey in five selected European countries (Germany [D], Spain [E], France [F], Italy [I], and the United Kingdom [UK]) among 257 dermatologists assessing awareness of different guidelines (European [EDF/EADV], German, Spanish, French, British)...
September 2013: Archives of Dermatological Research
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