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https://www.readbyqxmd.com/read/28820080/diet-quality-and-its-implications-on-the-cardio-metabolic-physical-and-general-health-of-older-men-the-concord-health-and-ageing-in-men-project-champ
#1
Rosilene V Ribeiro, Vasant Hirani, Alistair M Senior, Alison K Gosby, Robert G Cumming, Fiona M Blyth, Vasi Naganathan, Louise M Waite, David J Handelsman, Hal Kendig, Markus J Seibel, Stephen J Simpson, Fiona Stanaway, Margaret Allman-Farinelli, David G Le Couteur
The revised Dietary Guideline Index (DGI-2013) scores individuals' diets according to their compliance with the Australian Dietary Guideline (ADG). This cross-sectional study assesses the diet quality of 794 community-dwelling men aged 74 years and older, living in Sydney, Australia participating in the Concord Health and Ageing in Men Project; it also examines sociodemographic and lifestyle factors associated with DGI-2013 scores; it studies associations between DGI-2103 scores and the following measures: homoeostasis model assessment - insulin resistance, LDL-cholesterol, HDL-cholesterol, TAG, blood pressure, waist:hip ratio, BMI, number of co-morbidities and medications and frailty status while also accounting for the effect of ethnicity in these relationships...
July 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28819591/aggressive-vertebral-body-hemangioma-causing-compressive-myelopathy-two-case-reports
#2
Denver Steven Pinto, V Ravi Hoisala, Pavan Gupta, Parthasarathy Sarkar
INTRODUCTION: Hemangiomas are benign tumors characterized by proliferation of blood vessels. A few hemangiomas are aggressive, characterized by bone expansion and extraosseous extension. These benign tumors may be mistaken for metatasis resulting in unnecessary biopsies, which have a high risk of hemorrhage. These hemangiomas can spread not just into the paraspinal soft tissues but also into the epidural region of the spinal canal causing cord compression and paraparesis. These clinical symptoms can be relieved by surgical decompression of the posterior elements, embolization or radiotherapy...
March 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28819520/the-ban-on-blood-donation-on-men-who-have-sex-with-men-time-to-rethink-and-reassess-an-outdated-policy
#3
Georgios Karamitros, Nikolaos Kitsos, Ioanna Karamitrou
During the 1980s the HIV/AIDS epidemic outbreak occurred. Due to the high prevalence of the disease on men who had sex with men (MSM) a lifetime ban on blood donations on men who had sex with men (MSM) was implemented. In the recent years, organizations like the European Union (EU) and the World Health Organization (WHO) have established new guidelines introducing the term of "risky sexual behavior" without any reference to the sex orientation of the potential donor, however many countries are hesitant to review the ban on men who had sex with men (MSM)...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28819487/an-evaluation-of-wb123-antibody-elisa-in-individuals-treated-with-ivermectin-and-albendazole-and-implementation-challenges-in-africa
#4
Dziedzom Komi de Souza, Irene Offei Owusu, Joseph Otchere, Michelle Adimazoya, Kwadwo Frempong, Collins Stephen Ahorlu, Daniel Adjei Boakye, Michael David Wilson
The development of antibody testing for the diagnosis of lymphatic filariasis (LF) is intended to enhance the monitoring and evaluation activities of the Global Program for the Elimination of LF. This is due to the fact that antibody tests are expected to be the most sensitive at detecting exposure to LF compared to antigen that takes longer to develop. To this end a new antibody-based enzyme linked immunosorbent assay (ELISA) to Wuchereria bancrofti antigen Wb123 has been developed and further designed into a point of care rapid diagnostic test, under evaluation...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28819089/follow-up-practices-of-surgeons-and-medical-oncologists-in-australia-and-new-zealand-following-resection-of-esophagogastric-cancers
#5
Tim Chew, Tim Bright, Timothy J Price, David I Watson, Peter G Devitt
PURPOSE: Follow-up practices for patients who have undergone surgical resection of esophagogastric malignancies are variable and poorly documented. To better understand practice, a questionnaire was used to survey surgeons and medical oncologists to determine whether any consensus exists. METHODS: An opt-in online questionnaire was sent to esophagogastric surgeons and medical oncologists via the membership lists for the Australian and New Zealand Gastric and Oesophageal Surgery Association (ANZGOSA), the Australian Gastro-Intestinal Trials Groups (AGITG), and the Medical Oncology Group of Australia (MOGA)...
August 15, 2017: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28818842/what-s-new-in-paediatric-hypertension
#6
REVIEW
Rowena Lalji, Kjell Tullus
Paediatric hypertension predisposes to hypertension and cardiovascular disease in adult life. Despite clear guidelines, there remains a lack of screening. Diagnosis remains challenging given the high rate of false-positive high blood pressure (BP) readings at a single visit; thus, multiple visits are required to confirm the diagnosis. Depending on the normative data sets used, hypertension in overweight and obese children can be underestimated by up to 20%. Specific BP targets are required for subgroups such as adolescents, children with chronic kidney disease (CKD) and type 1 diabetes...
August 17, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28818815/mercury-concentrations-in-china-s-coastal-waters-and-implications-for-fish-consumption-by-vulnerable-populations
#7
Yindong Tong, Mengzhu Wang, Xiaoge Bu, Xin Guo, Yan Lin, Huiming Lin, Jing Li, Wei Zhang, Xuejun Wang
We assessed mercury (Hg) pollution in China's coastal waters, including the Bohai Sea, the Yellow Sea, the East China Sea and the South China Sea, based on a nationwide dataset from 301 sampling sites. A methylmercury (MeHg) intake model for humans based on the marine food chain and human fish consumption was established to determine the linkage between water pollutants and the pollutant intake by humans. The predicted MeHg concentration in fish from the Bohai Sea was the highest among the four seas included in the study...
August 14, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28818549/integration-of-dpc-and-clinical-microbiological-data-in-japan-reveals-importance-of-confirming-a-negative-follow-up-blood-culture-in-patients-with-mrsa-bacteremia
#8
Naoki Miyamoto, Koji Yahara, Rie Horita, Tomomi Yano, Naotaka Tashiro, Daiichi Morii, Atsuko Tsutsui, Kenichiro Yaita, Keigo Shibayama, Hiroshi Watanabe
Methicillin-resistant Staphylococcus aureus (MRSA) bacteremia is one of the commonest and most life-threatening of all infectious diseases. The morbidity and mortality rates associated with MRSA bacteremia are higher than those associated with bacteremia caused by other pathogens. A common guideline in MRSA bacteremia treatment is to confirm bacteremia clearance through additional blood cultures 2-4 days after initial positive cultures and as needed thereafter. However, no study has presented statistical evidence of how and to what extent confirming a negative follow-up blood culture impacts clinical outcome...
August 14, 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/28818544/trends-in-antimicrobial-resistance-in-bloodstream-infection-isolates-at-a-large-urban-hospital-in-malawi-1998-2016-a-surveillance-study
#9
Patrick Musicha, Jennifer E Cornick, Naor Bar-Zeev, Neil French, Clemens Masesa, Brigitte Denis, Neil Kennedy, Jane Mallewa, Melita A Gordon, Chisomo L Msefula, Robert S Heyderman, Dean B Everett, Nicholas A Feasey
BACKGROUND: Bacterial bloodstream infection is a common cause of morbidity and mortality in sub-Saharan Africa, yet few facilities are able to maintain long-term surveillance. The Malawi-Liverpool-Wellcome Trust Clinical Research Programme has done sentinel surveillance of bacteraemia since 1998. We report long-term trends in bloodstream infection and antimicrobial resistance from this surveillance. METHODS: In this surveillance study, we analysed blood cultures that were routinely taken from adult and paediatric patients with fever or suspicion of sepsis admitted to Queen Elizabeth Central Hospital, Blantyre, Malawi from 1998 to 2016...
August 14, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28818480/-infection-control-practices-while-performing-prostate-biopsies-in-france-a-ciafu-survey
#10
P Leduc, J D Doublet, F Bruyère, S Malavaud
In 2008, the French Public Health Committee admitted that associating ultrasound probe protection, and related precautions, and low-level disinfection would be equivalent to the intermediate level disinfection. In 2010, the French Urology Association (AFU) updated guidelines regarding trans-rectal prostate biopsies, namely preventive measures related to cross-transmission of infections. We report an evaluation of compliance to them, driven in 2016 by AFU's infection committee. Although not recommended, almost one third of the urologists still perform biopsies under general anesthesia, and two thirds of them ask for a urine culture before biopsies...
August 14, 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/28817862/practice-guidelines-for-hypertension
#11
David Zeigler, Anish Patel, Candace Zeigler
Hypertension is very prevalent in South Dakota affecting approximately one-third of the adult population. Management and treatment of the disease has recently been the subject of considerable debate centered on what should be the blood pressure goal depending on the patient's age and co-morbid conditions. Recently, a randomized trial of intensive versus standard blood pressure control indicated that a systolic blood pressure of less than 120 mmHg in patients at high risk for cardiovascular events but without diabetes, resulted in significantly lower rates of non-fatal major cardiovascular events and death from any cause...
2017: South Dakota Medicine: the Journal of the South Dakota State Medical Association
https://www.readbyqxmd.com/read/28816870/spinal-cord-injury-what-are-the-controversies
#12
Christopher S Ahuja, Gregory D Schroeder, Alexander R Vaccaro, Michael G Fehlings
Traumatic spinal cord injuries have a tremendous impact on individuals, families, and society as a whole. Substantial heterogeneity in the patient population, their presentation and underlying pathophysiology has sparked debates along the care spectrum from initial assessment to definitive treatment. This article reviews spinal cord injury (SCI) management followed by a discussion of the salient controversies in the field. Current care practices modeled on the American Association of Neurological Surgeons/Congress of Neurological Surgeons joint section guidelines are highlighted including key recommendations regarding immobilization, avoidance of hypotension, early International Standards for Neurological Classification of SCI examination and intensive care unit treatment...
September 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28816711/multiple-drug-intolerant-hypertension
#13
Andrea E Neculau, Liliana M Rogozea, Oana Andreescu, Loredana Jinga, Eleonora A Dinu, Diana Tint
CLINICAL FEATURES: The term multiple drug intolerance (MDI) is attributed to patients who experience adverse drug reactions to more than 3 different classes of medication without a known immunological mechanism. A special attention should be given to multiple drug-intolerant hypertension (MDI-HTN) that is a cause of drop out from treatment and consequent poor blood pressure control. Patients with MDIs account for 2%-5% of all population. The patient we present is a 63-year-old man with third-degree hypertension identified with intolerance to drugs from 4 major classes of antihypertensive medication...
May 26, 2017: American Journal of Therapeutics
https://www.readbyqxmd.com/read/28815840/current-status-of-home-blood-pressure-monitoring-in-asia-statement-from-the-hope-asia-network
#14
REVIEW
Yook-Chin Chia, Peera Buranakitjaroen, Chen-Huan Chen, Romeo Divinagracia, Satoshi Hoshide, Sungha Park, Jinho Shin, Saulat Siddique, Jorge Sison, Arieska Ann Soenarta, Guru Prasad Sogunuru, Jam Chin Tay, Yuda Turana, Ji-Guang Wang, Lawrence Wong, Yuqing Zhang, Kazuomi Kario
Hypertension represents a major burden in Asia, with a high prevalence rate but poor level of awareness and control reported in many countries in the region. Home blood pressure monitoring has been validated as an accurate and reliable measure of blood pressure that can help guide hypertension treatment as well as identify masked and white-coat hypertension. Despite its benefits, there has been limited research into home blood pressure monitoring in Asia. The authors reviewed the current evidence on home blood pressure monitoring in Asia, including but not limited to published literature, data presented at congresses, and national hypertension management guidelines to determine the current utilization of home blood pressure monitoring in clinical practice in the region...
August 17, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28814962/circulating-zinc-%C3%AE-2-glycoprotein-levels-are-low-in-newly-diagnosed-patients-with-metabolic-syndrome-and-correlate-with-adiponectin
#15
Lu Lei, Kejia Li, Ling Li, Xia Fang, Tingting Zhou, Cheng Zhang, Yong Luo, Hua Liu, Xiaoqiang Li, Hongting Zheng, Lin Zhang, Gangyi Yang, Lin Gao
BACKGROUND: Zinc-α2-glycoprotein (ZAG) is a novel adipokine that reduces insulin resistance, protecting against type 2 diabetes. However, past studies have been contradictory. This cross-sectional study aims to investigate the association of circulating ZAG with metabolic syndrome (MetS) in middle-aged and older Chinese adults. METHODS: Four hundred eighty nine individuals (234 healthy controls and 255 MetS patients) were examined. All individuals were screened for MetS according to the diagnostic guidelines of the United States National Cholesterol Education Program (NCEP) Expert Panel Adult Treatment Panel (ATP) III criteria...
2017: Nutrition & Metabolism
https://www.readbyqxmd.com/read/28814846/erratum-olmesartan-vs-ramipril-in-the-treatment-of-hypertension-and-associated-clinical-conditions-in-the-elderly-a-reanalysis-of-two-large-double-blind-randomized-studies-at-the-light-of-the-most-recent-blood-pressure-targets-recommended-by-guidelines-corrigendum
#16
https://www.readbyqxmd.com/read/28814835/efficacy-and-tolerability-of-two-different-formulations-of-atorvastatin-in-korean-patients-with-hypercholesterolemia-a-multicenter-prospective-randomized-clinical-trial
#17
Ju-Hee Lee, Sang-Hyun Kim, Dong-Ju Choi, Seung-Jea Tahk, Jung-Han Yoon, Si Wan Choi, Taek-Jong Hong, Hyo-Soo Kim
PURPOSE: This study was designed to compare the efficacy and tolerability of the generic formulation (Atorva(®)) and the reference formulation (Lipitor(®)) of atorvastatin, both at a dosage of 20 mg once daily. METHODS: This study was a prospective open-label, randomized controlled study. Hypercholesterolemic patients who had not achieved low-density lipoprotein (LDL) cholesterol goals according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III) guideline were randomized to generic formulation or reference formulation of atorvastatin...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28814664/pulmonary-arterial-hypertension-treatment-with-carvedilol-for-heart-failure-a-randomized-controlled-trial
#18
Samar Farha, Didem Saygin, Margaret M Park, Hoi I Cheong, Kewal Asosingh, Suzy Aa Comhair, Olivia R Stephens, Emir C Roach, Jacqueline Sharp, Kristin B Highland, Frank P DiFilippo, Donald R Neumann, W H Wilson Tang, Serpil C Erzurum
BACKGROUND: Right-sided heart failure is the leading cause of death in pulmonary arterial hypertension (PAH). Similar to left heart failure, sympathetic overactivation and β-adrenoreceptor (βAR) abnormalities are found in PAH. Based on successful therapy of left heart failure with β-blockade, the safety and benefits of the nonselective β-blocker/vasodilator carvedilol were evaluated in PAH. METHODS: PAH Treatment with Carvedilol for Heart Failure (PAHTCH) is a single-center, double-blind, randomized, controlled trial...
August 17, 2017: JCI Insight
https://www.readbyqxmd.com/read/28813512/implementation-of-a-comprehensive-intervention-for-patients-at-high-risk-of-cardiovascular-disease-in-rural-china-a-pragmatic-cluster-randomized-controlled-trial
#19
Xiaolin Wei, John D Walley, Zhitong Zhang, Guanyang Zou, Weiwei Gong, Simin Deng, Anthony D Harries, Joseph P Hicks, Marc K C Chong, James N Newell, Jieming Zhong, Min Yu
OBJECTIVE: This study aims to assess whether a standard intervention package of cardiovascular disease (CVD) care was being delivered effectively, and if it was associated with improved lifestyle and biomedical indicators. METHODS: In rural China, we implemented a pragmatic cluster randomized controlled trial for 12 months, randomized at the township hospital level, and compared with usual care. Intervention case management guideline, training and performance monitoring meeting and patient support activities were designed to fit within the job description of family doctors in the township hospitals and comprised: 1) prescription of a standardised package of medicines targeted at those with hypertension or diabetes; 2) advice about specific lifestyle interventions; and 3) advice about medication adherence...
2017: PloS One
https://www.readbyqxmd.com/read/28812380/analysis-of-an-8-hour-acetylcysteine-infusion-protocol-for-repeated-supratherapeutic-ingestion-rsti-of-paracetamol
#20
Anselm Wong, Naren Gunja, Richard McNulty, Andis Graudins
OBJECTIVES: In Australia, the treatment guideline for patients with repeated supratherapeutic ingestion (RSTI) of paracetamol recommends an abbreviated acetylcysteine regimen if the paracetamol concentration is low (<10 mg/L) and alanine aminotransferase (ALT) is normal or static after 8 hours of infusion. There are currently no studies of this recommendation. METHOD: A retrospective review of paracetamol overdose presentations from October 2009 to August 2016 in two hospital toxicology networks was performed...
August 16, 2017: Clinical Toxicology
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