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neuromuscular scoliosis

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https://www.readbyqxmd.com/read/29762339/the-relationship-between-fear-avoidance-and-neuromuscular-measures-of-function-in-patients-with-adult-degenerative-scoliosis
#1
Ram Haddas, Isador H Lieberman, Andrew Block
STUDY DESIGN: A prospective cohort study. OBJECTIVE: To examine the relationship of fear-avoidance beliefs and neuromuscular activity during gait in adult degenerative scoliosis (ADS) patients. SUMMARY OF BACKGROUND DATA: Among patients with chronic spine pain, fear-avoidance beliefs are predictive of poor surgical outcomes. Fear-avoidance occurs when patients perceive that movement will worsen underlying physical problems. This process leads them to restrict activity, which further heightens emotional distress...
May 14, 2018: Spine
https://www.readbyqxmd.com/read/29749884/perioperative-complications-and-risk-factors-in-neuromuscular-scoliosis-surgery
#2
Brandon J Toll, Amer F Samdani, M Burhan Janjua, Shashank Gandhi, Joshua M Pahys, Steven W Hwang
OBJECTIVE High rates of perioperative complications are associated with deformity correction in neuromuscular scoliosis. The current study aimed to evaluate complications associated with surgical correction of neuromuscular scoliosis and to characterize potential risk factors. METHODS Data were retrospectively collected from a single-center cohort of 102 consecutive patients who underwent spinal fusions for neuromuscular scoliosis between January 2008 and December 2016 and who had a minimum of 6 months of follow-up...
May 11, 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29735134/inter-and-intraobserver-reliability-of-pelvic-obliquity-measurement-methods-in-patients-with-cerebral-palsy
#3
M Wade Shrader, Emily M Andrisevic, Mohan V Belthur, Gregory R White, Carla Boan, William Wood
STUDY DESIGN: Retrospective, chart review. OBJECTIVES: The identification and management of pelvic obliquity in neuromuscular scoliosis can be difficult; therefore, appropriate evaluation of this pathology is important. Variations in presentation have resulted in various methods of measurement, without a consensus or gold standard measurement. This study is the evaluation of reliability of five methods commonly used to determine pelvic obliquity in the frontal plane...
May 2018: Spine Deformity
https://www.readbyqxmd.com/read/29726795/complication-rates-for-preexisting-baclofen-pumps-and-ventricular-shunts-following-scoliosis-correction-a-preliminary-study
#4
Jonathan Dallas, Katherine D Sborov, Bradley S Guidry, Silky Chotai, Christopher M Bonfield
OBJECTIVE Many patients undergoing spinal fusion for neuromuscular scoliosis have preexisting neurosurgical implants, including ventricular shunts (VSs) for hydrocephalus and baclofen pumps (BPs) for spastic cerebral palsy. Recent studies have discussed a possible increase in implant complication rates following spinal fusion, but published data are inconclusive. The authors therefore, sought to investigate: 1) the rate of implant complications following fusion, 2) possible causes of these complications, and 3) factors that place patients at higher risk for implant-related complications...
May 4, 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29623457/prediction-of-respiratory-function-in-patients-with-severe-scoliosis-on-the-basis-of-the-novel-individualized-spino-pelvic-index
#5
Zhi-Hui Zhao, Hong-da Bao, Chang-Chun Tseng, Ze-Zhang Zhu, Yong Qiu, Zhen Liu
OBJECTIVE: Our study aimed to evaluate the pulmonary function of patients with severe scoliosis after correcting standing height with spino-pelvic index (SPI). METHODS: Inclusion criteria: (1) with a coronal Cobb angle of more than 90°; (2) diagnosed as congenital (CS) or idiopathic scoliosis (IS); (3) aged between ten and 20 years; (4) with pulmonary function test (PFT) at the primary consultation. Patients with previous surgical intervention, with angular kyphosis, and with neuromuscular disease were excluded...
April 5, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29617870/wave-change-of-intraoperative-transcranial-motor-evoked-potentials-during-corrective-fusion-for-syndromic-and-neuromuscular-scoliosis
#6
Kei Ando, Kazuyoshi Kobayashi, Kenyu Ito, Mikito Tsushima, Masayoshi Morozumi, Satoshi Tanaka, Masaaki Machino, Kyotaro Ota, Yoshihiro Nishida, Naoki Ishiguro, Shiro Imagama
BACKGROUND: There is little information on intraoperative neuromonitoring during correction fusion surgery for syndromic scoliosis. OBJECTIVE: To investigate intraoperative TcMEPs and conditions (body temperature and blood pressure) for syndromic scoliosis. METHODS: The subjects were 23 patients who underwent 25 surgeries for corrective fusion using TcMEP. Patients were divided into groups based on a decrease (DA+) or no decrease (DA-) of the amplitude of the TcMEP waveform of ≥70%...
March 29, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29573446/scoliosis-vertebral-growth-plate-histomorphometry-comparisons-to-controls-growth-rates-and-compressive-stresses
#7
Donita I Bylski-Austrow, David L Glos, Eric J Wall, Alvin H Crawford
Scoliosis progression in skeletally immature patients depends on remaining growth. Relationships between vertebral growth plate histomorphometry, growth rates, and mechanical stresses have been reported in several animal studies. Hypertrophic zone heights and chondrocyte heights have been used to assess treatments that aim to modulate growth. The purpose of this study was to determine whether human vertebral physeal hypertrophic zone and cell heights differed between two groups: severe scoliosis and autopsy controls...
March 24, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29556213/novel-variants-in-individuals-with-ryr1-related-congenital-myopathies-genetic-laboratory-and-clinical-findings
#8
Joshua J Todd, Muslima S Razaqyar, Jessica W Witherspoon, Tokunbor A Lawal, Ami Mankodi, Irene C Chrismer, Carolyn Allen, Mary D Meyer, Anna Kuo, Monique S Shelton, Kim Amburgey, Dmitriy Niyazov, Pierre Fequiere, Carsten G Bönnemann, James J Dowling, Katherine G Meilleur
The ryanodine receptor 1-related congenital myopathies ( RYR1 -RM) comprise a spectrum of slow, rare neuromuscular diseases. Affected individuals present with a mild-to-severe symptomatology ranging from proximal muscle weakness, hypotonia and joint contractures to scoliosis, ophthalmoplegia, and respiratory involvement. Although there is currently no FDA-approved treatment for RYR1- RM, our group recently conducted the first clinical trial in this patient population (NCT02362425). This study aimed to characterize novel RYR1 variants with regard to genetic, laboratory, muscle magnetic resonance imaging (MRI), and clinical findings...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29521937/intraoperative-traction-may-be-a-viable-alternative-to-anterior-surgery-in-cerebral-palsy-scoliosis-%C3%A2-100-degrees
#9
Taylor J Jackson, Burt Yaszay, Joshua M Pahys, Anuj Singla, Firoz Miyanji, Suken A Shah, Paul D Sponseller, Peter O Newton, John M Flynn, Patrick J Cahill
BACKGROUND: For large scoliosis, 2 strategies to maximize correction include intraoperative traction and/or anterior release. It is unclear which patients will benefit the most form either approach. The purpose of our study is to compare the radiographic, perioperative clinical outcomes, and health-related quality of life (HRQoL) outcomes of 2 approaches when used in severe neuromuscular scoliosis in the setting of cerebral palsy (CP). METHODS: In total, 23 patients with minimum 2-year follow-up, major curves ≥100 degrees, and in whom treatment included posterior spinal fusion were evaluated...
May 2018: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/29503679/psoas-morphology-differs-between-supine-and-sitting-magnetic-resonance-imaging-lumbar-spine-implications-for-lateral-lumbar-interbody-fusion
#10
Aaron J Buckland, Bryan M Beaubrun, Evan Isaacs, John Moon, Peter Zhou, Sam Horn, Gregory Poorman, Jared C Tishelman, Louis M Day, Thomas J Errico, Peter G Passias, Themistocles Protopsaltis
Study Design: Retrospective radiological review. Purpose: To quantify the effect of sitting vs supine lumbar spine magnetic resonance imaging (MRI) and change in anterior displacement of the psoas muscle from L1-L2 to L4-L5 discs. Overview of Literature: Controversy exists in determining patient suitability for lateral lumbar interbody fusion (LLIF) based on psoas morphology. The effect of posture on psoas morphology has not previously been studied; however, lumbar MRI may be performed in sitting or supine positions...
February 2018: Asian Spine Journal
https://www.readbyqxmd.com/read/29444762/hemimegalencephaly-with-bannayan-riley-ruvalcaba-syndrome
#11
Ryan Ghusayni, Monisha Sachdev, William Gallentine, Mohamad A Mikati, Marie T McDonald
Hemimegalencephaly is known to occur in Proteus syndrome, but has not been reported, to our knowledge, in the other PTEN mutation-related syndrome of Bannayan-Riley-Ruvalcaba. Here, we report a patient with Bannayan-Riley-Ruvalcaba syndrome who also had hemimegalencephaly and in whom the hemimegalencephaly was evident well before presentation of the characteristic manifestations of Bannayan-Riley-Ruvalcaba syndrome. An 11-year-old boy developed drug-resistant focal seizures on the fifth day of life. MRI revealed left hemimegalencephaly...
February 1, 2018: Epileptic Disorders: International Epilepsy Journal with Videotape
https://www.readbyqxmd.com/read/29422531/circulating-mirnas-as-diagnostic-biomarkers-for-adolescent-idiopathic-scoliosis
#12
José Luis García-Giménez, Pedro Antonio Rubio-Belmar, Lorena Peiró-Chova, David Hervás, Daymé González-Rodríguez, José Santiago Ibañez-Cabellos, Paloma Bas-Hermida, Salvador Mena-Mollá, Eva María García-López, Federico V Pallardó, Teresa Bas
The aetiology of adolescent idiopathic scoliosis (AIS) has been linked to many factors, such as asymmetric growth, neuromuscular condition, bone strength and genetic background. Recently, epigenetic factors have been proposed as contributors of AIS physiopathology, but information about the molecular mechanisms and pathways involved is scarce. Regarding epigenetic factors, microRNAs (miRNAs) are molecules that contribute to gene expression modulation by regulating important cellular pathways. We herein used Next-Generation Sequencing to discover a series of circulating miRNAs detected in the blood samples of AIS patients, which yielded a unique miRNA biomarker signature that diagnoses AIS with high sensitivity and specificity...
February 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29419720/minimally-invasive-surgery-for-neuromuscular-scoliosis-results-and-complications-in-a-series-of-one-hundred-patients
#13
Lotfi Miladi, Mathilde Gaume, Nejib Khouri, Michael Johnson, Vicken Topouchian, Christophe Glorion
STUDY DESIGN: A retrospective review. OBJECTIVES: To report the results of an alternative technique using a minimally invasive fusionless surgery. The originality is based on the progressive correction of the deformities with proximal and distal fixation and on the reliability of the pelvic fixation using ilio-sacral screws on osteoporotic bones. SUMMARY OF BACKGROUND DATA: Spinal deformities are common in neuromuscular diseases. Conventional treatment involves bracing, followed by spinal instrumented fusion...
February 6, 2018: Spine
https://www.readbyqxmd.com/read/29411177/pseudarthrosis-in-adult-and-pediatric-spinal-deformity-surgery-a-systematic-review-of-the-literature-and-meta-analysis-of-incidence-characteristics-and-risk-factors
#14
REVIEW
Nathan E How, John T Street, Marcel F Dvorak, Charles G Fisher, Brian K Kwon, Scott Paquette, Justin S Smith, Christopher I Shaffrey, Tamir Ailon
We conducted a systematic review with meta-analysis and qualitative synthesis. This study aims to characterize pseudarthrosis after long-segment fusion in spinal deformity by identifying incidence rates by etiology, risk factors for its development, and common features. Pseudarthrosis can be a painful and debilitating complication of spinal fusion that may require reoperation. It is poorly characterized in the setting of spinal deformity. The MEDLINE, EMBASE, and Cochrane databases were searched for clinical research including spinal deformity patients treated with long-segment fusions reporting pseudarthrosis as a complication...
February 6, 2018: Neurosurgical Review
https://www.readbyqxmd.com/read/29369154/combining-bilateral-magnetically-controlled-implants-inserted-parallel-to-the-spine-with-rib-to-pelvis-fixation-surgical-technique-and-early-results
#15
Anna K Hell, Katharina Groenefeld, Konstantinos Tsaknakis, Lena Braunschweig, Heiko M Lorenz
Spine-based fixation of magnetically controlled lengthening devices has been successfully performed for children with early-onset scoliosis. However, spinal manipulation may lead to ossifications, stiffness, and autofusion as previously described. To avoid these problems, a surgical technique combining bilateral externally controlled magnetic device implantation with a rib cradle and pelvic hook fixation was introduced by us in 2011. By using a bilateral single-rib or double-rib cradle fixation and a pelvic hook, the magnetic device is percutaneously inserted...
January 23, 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29355795/surgical-management-of-myelomeningocele-related-spinal-deformities
#16
Sergey O Ryabykh, Olga M Pavlova, Dmitry M Savin, Alexander V Burtsev, Alexander V Gubin
OBJECTIVE: To evaluate the optimal timing and type of surgical treatment of myelomeningocele (MMC)-related spinal deformities and long-term follow-up of surgical treatment. METHODS: We reviewed and presented clinical pictures, treatment strategies and results of 20 patients with MMC-related spinal deformities treated at our center between 2010 and 2017. RESULTS: The average patient age was 6.3 years. The average preoperative neurologic status according to a modified Japan Orthopedic Association (mJOA) scale was 7...
April 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29354726/outcomes-and-complications-of-s2-alar-iliac-fixation-technique-in-patients-with-neuromuscular-scoliosis-experience-in-a-third-level-pediatric-hospital
#17
Carlos Segundo Montero, David Alberto Meneses, Fernando Alvarado, Wilmer Godoy, Diana Isabel Rosero, Jose Manuel Ruiz
Background: Multiple techniques are utilized for distal fixation in patients with neuromuscular scoliosis. Although there is evidence of benefit with S2 alar iliac (S2AI) fixation, this remains controversial. The objective of this study is to evaluate the radiological outcomes and complications associated with this surgical technique in a pediatric population. Methods: An observational retrospective case series study was performed. All pediatric patients between January 2011 and February 2014 diagnosed with neuromuscular scoliosis associated with pelvic obliquity, which required surgery with fixation unto S2AI, were included...
December 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29340778/successful-surgery-for-a-neuromuscular-scoliosis-patient-by-pulmonary-rehabilitation-with-forced-vital-capacity-below-30
#18
Kai Han, Yongqian Wang, Shangbin Cui, Caixia Xu, Peiqiang Su
A rare case of a 15-year-old male patient with neuromuscular scoliosis with forced vital capacity (FVC) below 30%, who went through a successful surgery without any pulmonary complications, is reported herein. The patient had obvious asymmetric shoulders and poor exercise tolerance. The Cobb's angle of the main thoracic curve was 62.8°, and FVC in sitting position was 18% of predictive value. After skull traction and pulmonary rehabilitation, the FVC was still below 30%, and he finally went through surgery under this serious condition...
January 16, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29318413/evaluation-of-postoperative-fever-after-surgical-correction-of-neuromuscular-scoliosis-implication-on-management
#19
Mohamed Abdelhamid Ali Yousef, Scott Rosenfeld
BACKGROUND: Scoliosis is a common deformity in patients with neuromuscular disorders which usually necessitates surgical correction. Patients with neuromuscular scoliosis are characterized by increased incidence of associated medical co-morbidities and higher postoperative complication rate; therefore, these patients are often managed with a wide multidisciplinary care team. Postoperative fever is a frequent complication after surgery which is often routinely investigated using different workup tests to rule out infection...
January 9, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29302566/bridging-the-gap-between-observation-and-brace-treatment-for-adolescent-idiopathic-scoliosis
#20
Eric Chun Pu Chu, Kevin Hsu Kai Huang
Adolescent idiopathic scoliosis (AIS) remains the most common and potentially severe form of scoliosis during the rapid growth period. It is generally accepted that AIS is a multifactorial disease controlled by genetic, hormonal, neuromuscular, and environmental factors. Herein, we describe a case of 12-year-old scoliotic girl with a double curve of initially 26° thoracic and 23° lumbar, seeking chiropractic care. The therapy was provided three times/twice a week for 6 months. Adjustments of the spine through chiropractic, both soreness and mobility, were shown to improve...
April 2017: Journal of Family Medicine and Primary Care
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