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https://www.readbyqxmd.com/read/28749577/prevalence-and-determinants-of-antibiotic-exposure-in-infants-a-population-derived-australian-birth-cohort-study
#1
Hayley Anderson, Peter Vuillermin, Kim Jachno, Katrina J Allen, Mimi Lk Tang, Fiona Collier, Andrew Kemp, Anne-Louise Ponsonby, David Burgner
AIM: The aim of this study was to describe antibiotic exposure in Australian infants during the first year of life, focusing on antibiotic class, indication, risk factors associated with exposure and comparison with international counterparts. METHODS: The Barwon Infant Study is a birth cohort study (n = 1074) with an unselected antenatal sampling frame from a large regional centre in Victoria, Australia. Longitudinal data on infection and medication were collected at 1, 3, 6, 9 and 12 months by parental questionnaire and from general practitioner and hospital records...
July 27, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28749055/a-failure-to-be-candid
#2
Jennifer McGuirl
I was a second-year neonatal-perinatal fellow in a meeting between other members of the neonatal intensive care team and parents who had just received devastating news about their planned-for and highly desired baby, born after what had been an uncomplicated pregnancy. At home, a little sister was waiting to meet her new brother. These conversations are never easy, but this one I found particularly disturbing. John had been born at term via emergency cesarean section after his mother, Muriel, had come for a routine obstetrical visit and reported decreased fetal movement...
July 2017: Hastings Center Report
https://www.readbyqxmd.com/read/28748627/genetic-ablation-of-carbonic-anhydrase-ix-disrupts-gastric-barrier-function-via-claudin-18-downregulation-and-acid-backflux
#3
Taolang Li, Xuemei Liu, Brigitte Riederer, Katerina Nikolovska, Anurag Kumar Singh, Kari A Mäkelä, Anna Seidler, Yongjian Liu, Gerolf Gros, Helmut Bartels, Karl Heinz Herzig, Ursula Seidler
AIM: The study aims to explore the molecular mechanisms for the parietal cell loss and fundic hyperplasia observed in gastric mucosa of mice lacking the carbonic anhydrase 9 (CAIX). METHODS: We assessed the ability of CAIX knockout and WT gastric surface epithelial cells to withstand luminal acid load by measuring the pHi of exteriorized gastric mucosa in vivousing two photon confocal laser scanning microscopy. Cytokines and claudin-18A2 expression was analyzed by RT-PCR...
July 27, 2017: Acta Physiologica
https://www.readbyqxmd.com/read/28748233/caries-prevalence-and-risk-assessment-in-thuringian-infants-germany
#4
Yvonne Wagner, Roswitha Heinrich-Weltzien
PURPOSE: To determine the caries prevalence and experience in Thuringian infants and to assess their caries risk. MATERIAL AND METHODS: The subjects were participants in a regional preventive programme, a birth cohort study with the aim of preventing caries. In the first year of life, children were invited to a dental examination at the Jena University Hospital. Dental caries was scored using WHO diagnostic criteria at the d1-level without radiography. Children were categorised as being of low, moderate or high risk for caries according to the caries-risk assessment tool of the American Academy of Pediatric Dentistry (AAPD)...
July 25, 2017: Oral Health & Preventive Dentistry
https://www.readbyqxmd.com/read/28747615/isolated-congenital-megacystis-with-spontaneous-resolution-a-case-report
#5
Toshihiko Nakamura
The patient was a male infant with an antenatal diagnosis of huge intraabdominal mass. Prenatal ultrasound at 35 weeks gestation revealed a markedly enlarged cystic mass in the lower abdomen. After birth at 38 weeks, the infant was allowed to void spontaneously and passed meconium. Ultrasonography showed an enlarged bladder with wall thickness of 2.9 mm and no hydronephrosis. Voiding cystourethrograms showed no evidence of vesicoureteral reflex and posterior urethral valve. The post-void residuals were 15 mL at 11 days of life, 5 mL at 1 month and 0 mL at 5 months...
July 26, 2017: Fukushima Journal of Medical Science
https://www.readbyqxmd.com/read/28747304/investigating-the-impact-of-the-english-health-inequalities-strategy-time-trend-analysis
#6
Ben Barr, James Higgerson, Margaret Whitehead
Objective To investigate whether the English health inequalities strategy was associated with a decline in geographical health inequalities, compared with trends before and after the strategy.Design Time trend analysis.Setting Two groups of lower tier local authorities in England. The most deprived, bottom fifth and the rest of England.Intervention The English health inequalities strategy-a cross government strategy implemented between 1997 and 2010 to reduce health inequalities in England. Trends in geographical health inequalities were assessed before (1983-2003), during (2004-12), and after (2013-15) the strategy using segmented linear regression...
July 26, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28747097/tissue-engineering-strategies-to-improve-osteogenesis-in-the-juvenile-swine-alveolar-cleft-model
#7
Montserrat Caballero, Donna C Jones, Zhengyuan Shan, Sajjad Soleimani, John A van Aalst
Alveolar <b>(gumline)</b> clefts are the most common congenital bone defect in humans, affecting 1 in 700 live births. Treatment <b>to repair these bony</b> defects relies on autologous, <b>cancellous</b> bone transfer from the iliac crest. This harvest requires a second surgical site <b>with increased </b>surgical time associated with potential complications, <b>while providing only limited cancellous bone</b>. Improvements in treatment protocols that avoid these limitations would be beneficial to patients with clefts and other craniofacial bone defects...
July 26, 2017: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/28746441/economic-evaluation-and-efficacy-of-strategic-selective-treatment-of-gastrointestinal-parasites-in-dairy-calves
#8
Yuly Andrea Caicedo Blanco, Jonata de Melo Barbieri, Renato Ribeiro de Lima, Marcos Aurélio Lopes, Eduardo Mitke Brandão Reis, Christiane Maria Barcellos Magalhães da Rocha, Adriana de Souza Coutinho, Antônio Marcos Guimarães
In the Experimental Farm of the Universidade Federal de Lavras (EF-UFLA), state of Minas Gerais, Brazil, on their day of birth, female Holstein calves were randomly selected and placed into two groups containing fifteen animals each: Strategic-Selective Treatment (S-ST) or Conventional Treatment (CT). In the S-ST, calves were treated after coproparasitological examinations according to criteria established previously by the researchers. Calves in the CT were treated according to the opinion of the veterinarian of EF-UFLA...
April 2017: Revista Brasileira de Parasitologia Veterinária, Brazilian Journal of Veterinary Parasitology
https://www.readbyqxmd.com/read/28746353/delayed-breastfeeding-initiation-and-infant-survival-a-systematic-review-and-meta-analysis
#9
Emily R Smith, Lisa Hurt, Ranadip Chowdhury, Bireshwar Sinha, Wafaie Fawzi, Karen M Edmond
OBJECTIVE: To assess the existing evidence regarding breastfeeding initiation time and infant morbidity and mortality. STUDY DESIGN: We conducted a systematic review and meta-analysis. We searched Pubmed, Embase, Web of Science, CINAHL, Popline, LILACS, AIM, and Index Medicus to identify existing evidence. We included observational studies and randomized control trials that examined the association between breastfeeding initiation time and mortality, morbidity, or nutrition outcomes from birth through 12 months of age in a population of infants who all initiated breastfeeding...
2017: PloS One
https://www.readbyqxmd.com/read/28746325/effect-of-maternal-socio-demographic-factors-and-child-feeding-practice-on-wasting-among-under-five-years-children-in-slum-area-of-rupandehi-district-in-nepal
#10
S Gautam, S Ruchal, B Timalsina, D Acharya, B Khadka, V Gautam, J K Singh
INTRODUCTION: Childhood wasting although well studied elsewhere, it has not been well understood about in slum area of Nepal. This study aimed to assess effect of socio-demographic factors and child feeding practice in the determination of wasting among the children under five years of age in slum area of Nepal. METHODS: A community based cross-sectional study was performed among 150 children under five years of age from the slum area of Nepal between 1st January and 28th February 2013 using simple random sampling techniques...
April 2017: JNMA; Journal of the Nepal Medical Association
https://www.readbyqxmd.com/read/28746260/perinatal-hiv-infection-and-exposure-and-their-association-with-dental-caries-in-nigerian-children
#11
Modupe Coker, Samer El-Kamary, Cyril Enwonwu, William Blattner, Patricia Langenberg, Emmanuel Mongodin, Paul Akhigbe, Ozo Obuekwe, Austin Omoigberale, Manhattan Charurat
BACKGROUND: Although HIV infection is associated with well-known oral pathologies, there remains a dearth of comparative studies aimed at determining the association between HIV infection/exposure and early childhood caries. METHODS: This is a cross-sectional study using a convenience sample of 3 groups of children receiving care at a tertiary care hospital in Nigeria. The groups include HIV infected (HI); HIV exposed but uninfected (HEU); and HIV unexposed and uninfected (HUU) children aged 6 through 72 months...
July 19, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28745809/rural-urban-differentials-in-the-rates-and-factors-associated-with-post-neonatal-mortality-in-nigeria-evidence-from-the-2013-national-household-survey
#12
Emmanuel Olorunleke Adewuyi, Samuel John Adama, Kazeem Adefemi, Olufemi Abayomi Akintunde, Lydia Babatunde Bulndi
BACKGROUND: The burden of post-neonatal mortality remains considerably high in Nigeria. This study examines the rural-urban differences in post-neonatal mortality rates (PNMR) and associated factors in Nigeria. METHODS: Dataset from the 2013 Nigeria demographic and health survey, disaggregated by rural-urban residence, was analyzed. PNMR was reported using frequency tabulation, whereas, factors associated were first evaluated using Chi-Square test and further examined using multivariable logistic regression analysis...
July 26, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28745394/opioids-for-chronic-non-cancer-pain-in-children-and-adolescents
#13
REVIEW
Tess E Cooper, Emma Fisher, Andrew L Gray, Elliot Krane, Navil Sethna, Miranda Al van Tilburg, Boris Zernikow, Philip J Wiffen
BACKGROUND: Pain is a common feature of childhood and adolescence around the world, and for many young people, that pain is chronic. The World Health Organization guidelines for pharmacological treatments for children's persisting pain acknowledge that pain in children is a major public health concern of high significance in most parts of the world. While in the past, pain was largely dismissed and was frequently left untreated, views on children's pain have changed over time, and relief of pain is now seen as importantWe designed a suite of seven reviews on chronic non-cancer pain and cancer pain (looking at antidepressants, antiepileptic drugs, non-steroidal anti-inflammatory drugs, opioids, and paracetamol as priority areas) in order to review the evidence for children's pain utilising pharmacological interventions in children and adolescents...
July 26, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28745186/there-s-nothing-like-a-bit-of-research-to-give-flagging-spirits-a-boost
#14
Jane Bates
A recent study in Spain suggests that our month of birth can make us more susceptible to certain health conditions.
July 26, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28744935/emergency-department-presentations-in-infants-predictors-from-an-australian-birth-cohort
#15
Julia Crilly, Cate M Cameron, Paul A Scuffham, Norm Good, Rani Scott, Gabor Mihala, Amy Sweeny, Gerben Keijzers
AIM: Infants under 12 months of age are disproportionately represented amongst emergency department (ED) presentations, and infants are more likely to be frequent ED users. This study aimed to describe and identify psychosocial predictors of ED presentation in infants. METHODS: A prospective birth cohort from Queensland and New South Wales (Environments for Healthy Living) was used to understand infant health service use. Baseline and 12-month questionnaire data pertaining to children born between 2006 and 2011 were used to identify predictors of ED presentation, using multiple regression analysis...
July 25, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28743731/shifting-disease-burden-in-low-and-middle-income-countries-a-14-year-survival-analysis-of-childhood-mortality-in-bangladesh
#16
REVIEW
Olakunle Alonge, Siran He, Dewan Emdadul Hoque, Shumona Sharmin Salam, Irteja Islam, Shams El-Arifeen, Adnan A Hyder
BACKGROUND: The objective of this study is to compare all-cause mortality and drowning-specific mortality rates and survival times among birth cohorts of children from rural Bangladesh over a 14-year period. METHOD: Seven birth cohorts of children aged 12-59 months were created using data from the Matlab Health and Demographic Surveillance System in Bangladesh. Each cohort represents children born within a 2-year interval between 1 July 1995 and 30 June 2009, who were then evaluated over a 2-year snapshot...
July 25, 2017: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/28743535/discharge-on-the-day-of-birth-parental-response-and-health-and-schooling-outcomes
#17
Hans Henrik Sievertsen, Miriam Wüst
Exploiting the Danish roll-out of same-day discharge policies after uncomplicated births, we find that treated newborns have a higher probability of hospital readmission in the first month after birth. While these short-run effects may indicate substitution of hospital stays with readmissions, we also find that-in the longer run-a same-day discharge decreases children's 9th grade GPA. This effect is driven by children and mothers, who prior to the policy change would have been least likely to experience a same-day discharge...
July 4, 2017: Journal of Health Economics
https://www.readbyqxmd.com/read/28743238/determinants-of-stunting-and-severe-stunting-among-burundian-children-aged-6-23-months-evidence-from-a-national-cross-sectional-household-survey-2014
#18
Sandra Nkurunziza, Bruno Meessen, Jean-Pierre Van Geertruyden, Catherine Korachais
BACKGROUND: Burundi is one of the poorest countries and is among the four countries with the highest prevalence of stunting (58%) among children aged less than 5 years. This situation undermines the economic growth of the country as undernutrition is strongly associated with less schooling and reduced economic productivity. Identifying the determinants of stunting and severe stunting may help policy-makers to direct the limited Burundian resources to the most vulnerable segments of the population, and thus make it more cost effective...
July 25, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28743049/risk-factors-for-maternal-anaemia-and-low-birth-weight-in-pregnant-women-living-in-rural-india-a%C3%A2-prospective-cohort-study
#19
A S Ahankari, P R Myles, J V Dixit, L J Tata, A W Fogarty
OBJECTIVE: The aim of this prospective study was to estimate the prevalence and risk factors for maternal anaemia and low birth weight (LBW) in pregnant women living in Maharashtra state, India. STUDY DESIGN: This is a prospective study. METHODS: Women between 3 and 5 months of pregnancy were recruited from 34 villages based in Maharashtra state. Baseline data collection, anthropometric measurements and blood investigations were performed...
July 22, 2017: Public Health
https://www.readbyqxmd.com/read/28742106/epidemiology-of-enteroaggregative-escherichia-coli-infections-and-associated-outcomes-in-the-mal-ed-birth-cohort
#20
Elizabeth T Rogawski, Richard L Guerrant, Alexandre Havt, Ila F N Lima, Pedro H Q S Medeiros, Jessica C Seidman, Benjamin J J McCormick, Sudhir Babji, Dinesh Hariraju, Ladaporn Bodhidatta, Jasmin Shrestha, Japhat Anania, Athanasia Maro, Amidou Samie, Pablo Peñataro Yori, Shahida Qureshi, Mustafa Mahfuz, Pascal O Bessong, Margaret N Kosek, Tahmeed Ahmed, Zulfiqar A Bhutta, Dennis R Lang, Michael Gottlieb, Eric R Houpt, Aldo A M Lima
BACKGROUND: Enteroaggregative E. coli (EAEC) have been associated with mildly inflammatory diarrhea in outbreaks and in travelers and have been increasingly recognized as enteric pathogens in young children with and without overt diarrhea. We examined the risk factors for EAEC infections and their associations with environmental enteropathy biomarkers and growth outcomes over the first two years of life in eight low-resource settings of the MAL-ED study. METHODS: EAEC infections were detected by PCR gene probes for aatA and aaiC virulence traits in 27,094 non-diarrheal surveillance stools and 7,692 diarrheal stools from 2,092 children in the MAL-ED birth cohort...
July 24, 2017: PLoS Neglected Tropical Diseases
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