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https://www.readbyqxmd.com/read/29783267/-conceptual-approaches-to-the-investigation-of-a-problem-of-professional-training-of-physical-therapists
#1
Anna V Fastivetz, Pavlo V Khomenko, Inna E Shaparenko
OBJECTIVE: Introduction:The level of people's health and its preservation is a medical problem that requires the optimal solution and the need to improve the management of the system of measures to achieve the goal. According to specialists, the health of Ukrainian people is accompanied by high mortality, significant parameters of disability and morbidity and a decrease in the average life expectancy. Diseases that lead to such negative medical and social and socio-economic consequences are so-called "illnesses of a way of life" or "diseases of civilization"...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783246/-%C3%B0-%C3%B0-%C3%B1-%C3%B0-%C3%B0-%C3%B1-%C3%B1-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B1-%C3%B0-%C3%B0-%C3%B1-%C3%B0-%C3%B0-%C3%B1-%C3%B0-%C3%B0-%C3%B0-%C3%B1-%C3%B0-%C3%B0-%C3%B1-%C3%B1-%C3%B1-%C3%B0%C2%BA-%C3%B0-%C3%B0-%C3%B0-%C3%B1-%C3%B0-%C3%B0-%C3%B1-%C3%B0-%C3%B0-%C3%B0-%C3%B1-%C3%B1-%C3%B1-%C3%B1-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0-%C3%B0
#2
Nataliia O Rynhach, Vasyl M Mykhalchuk, Anatolii H Krut
OBJECTIVE: Introduction: This publication focuses on role of physical activity in promoting and protecting health and well-being. Physical activity is a significant risk factor for noncommunicable diseases. The public's awareness of the risk factors of non-communicable diseases is an important component of their control. The aim: To estimate the level of knowledge of the working age population regarding the essence of a healthy lifestyle and risk factors for non-communicable diseases (with an emphasis on lack of physical activity and its consequences) according to qualitative and quantitative sociological research...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783171/ghep-isfg-collaborative-exercise-on-mixture-profiles-ghep-mix06-reporting-conclusions-results-and-evaluation
#3
P A Barrio, M Crespillo, J A Luque, M Aler, C Baeza-Richer, L Baldassarri, E Carnevali, P Coufalova, I Flores, O García, M A García, R González, A Hernández, V Inglés, G M Luque, A Mosquera-Miguel, S Pedrosa, M L Pontes, M J Porto, Y Posada, M I Ramella, T Ribeiro, E Riego, A Sala, V G Saragoni, A Serrano, S Vannelli
One of the main goals of the Spanish and Portuguese-Speaking Group of the International Society for Forensic Genetics (GHEP-ISFG) is to promote and contribute to the development and dissemination of scientific knowledge in the field of forensic genetics. Due to this fact, GHEP-ISFG holds different working commissions that are set up to develop activities in scientific aspects of general interest. One of them, the Mixture Commission of GHEP-ISFG, has organized annually, since 2009, a collaborative exercise on analysis and interpretation of autosomal short tandem repeat (STR) mixture profiles...
May 18, 2018: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/29783150/electrophoretic-deposition-of-dexamethasone-loaded-gelatin-nanospheres-chitosan-coating-and-its-dual-function-in-anti-inflammation-and-osteogenesis
#4
Hongfei Qi, Qiang Chen, Hailong Ren, Xianglong Wu, Xianhu Liu, Tingli Lu
Surface modification of metallic implants with bioactive and biodegradable coatings could be a promising approach for bone regeneration. The objective of this study was to prepare chitosan/gelatin nanospheres (GNs) composite coating for the delivery of dexamethasone (DEX). GNs with narrow size distribution and negative surface charge were firstly prepared by a two-step desolvation method. Homogeneous and stable gelatin nanospheres/chitosan (GNs/CTS) composite coatings were formed by electrophoretic deposition (EPD)...
May 18, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29783141/graphene-oxide-and-carbon-nanodots-co-modified-biobr-nanocomposites-with-enhanced-photocatalytic-4-chlorophenol-degradation-and-mechanism-insight
#5
Songying Qu, Yuhan Xiong, Jun Zhang
Non-metallic graphene oxide (GO) and carbon nanodots (CDots) co-doped BiOBr ternary system (GO/CDots/BiOBr) were successfully synthesized via a simple one-step solvothermal process. The compositional characterization, optical and electrical properties of photocatalysts were investigated in detail. The prepared ternary photocatalysts possessed the excellent visible-light driven photocatalytic 4-chlorophenol (4-CP) degradation. Additionally, the 4-CP removal efficiencies decreased in the order of GO/CDots/BiOBr (88...
May 15, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29783126/systemic-therapy-for-intermediate-and-advanced-hepatocellular-carcinoma-sorafenib-and-beyond
#6
REVIEW
Jean-Luc Raoul, Masatoshi Kudo, Richard S Finn, Julien Edeline, Maria Reig, Peter R Galle
The hepatocellular carcinoma (HCC) treatment landscape changed a decade ago, with sorafenib demonstrating survival benefit in the first-line setting and becoming the first systemic therapy to be approved for HCC. More recently, regorafenib and nivolumab have received approval in the second-line setting after sorafenib, with further positive phase 3 studies emerging in the first line (lenvatinib non-inferior to sorafenib) and second line versus placebo (cabozantinib and ramucirumab). A key recommendation in the management of patients receiving sorafenib is to promote close communication between the patient and the physician so that adverse events (AEs) are detected early and severe AEs can be prevented...
May 17, 2018: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/29783122/bix-01294-promotes-the-differentiation-of-adipose-mesenchymal-stem-cells-into-adipocytes-and-neural-cells-in-arbas-cashmere-goats
#7
Qing Wang, Xiao Wang, Defang Lai, Jin Deng, Zhuang Hou, Hao Liang, Dongjun Liu
Chromatin remodeling plays an essential role in regulating gene transcription. BIX-01294 is a specific inhibitor of histone methyltransferase G9a, which is responsible for methylation of histone H3 lysine 9 (H3K9) that can also regulate DNA methylation and chromatin remodeling. The purpose of this study was to investigate the effects of BIX-01294 on the potential of goat adipose derived stem cells (gADSCs) to differentiate into adipocytes and neural cells. To accomplish this, BIX-01294 was used to treat gADSCs for 24 h, and the global level of DNA methylation as well as the expression of genes related to cell proliferation, apoptosis and pluripotency were detected...
May 14, 2018: Research in Veterinary Science
https://www.readbyqxmd.com/read/29783117/changes-in-soil-nitrogen-dynamics-caused-by-prescribed-fires-in-dense-gorse-lands-in-sw-pyrenees
#8
Leire Múgica, Rosa M Canals, Leticia San Emeterio
Rural depopulation, abandonment of traditional land uses and decrease of extensive stockfarming is accelerating shrub encroachment in mountain areas. In NW Spain, gorse (Ulex gallii Planch.) is expanding, developing dense shrublands that accumulate high fuel-loads, ignite easily and persist during long periods as alternate stable states. Under this scenario, traditional bush-to-bush farming fires are being replaced by high fuel-load burnings performed by specialised teams to reduce fuels and promote mosaic landscapes...
May 18, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29783107/effect-of-cd-on-growth-physiological-response-cd-subcellular-distribution-and-chemical-forms-of-koelreuteria-paniculata
#9
Lan Peng Yang, Jian Zhu, Ping Wang, Jing Zeng, Rong Tan, Yu Zhong Yang, Zhi Ming Liu
Koelreuteria paniculata were cultivated in nutrient solution with different concentrations of Cd (0, 50, 150, 250 and 500 µM) and sampled after 90 days. The resistance, translocation, accumulation and stress responses in Koelreuteria paniculata were investigated by hydroponic experiments. The results showed that Koelreuteria paniculata is an efficient Cd excluder that can tolerate high concentrations of Cd (up to 150-250 µM of Cd). The concentration of Cd never exceeds 5 ppm in leaves and 10 ppm in roots...
May 18, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29783090/inter-and-intra-disciplinary-collaboration-and-patient-safety-outcomes-in-u-s-acute-care-hospital-units-a-cross-sectional-study
#10
Chenjuan Ma, Shin Hye Park, Jingjing Shang
BACKGROUND: Collaboration among healthcare providers has been considered a promising strategy for improving care quality and patient outcomes. Despite mounting evidence demonstrating the impact of collaboration on outcomes of healthcare providers, there is little empirical evidence on the relationship between collaboration and patient safety outcomes, particularly at the patient care unit level. OBJECTIVES: The purpose of this study is to identify the extent to which interdisciplinary collaboration between nurses and physicians and intradisciplinary collaboration among nurses on patient care units are associated with patient safety outcomes...
May 2, 2018: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29783077/effects-of-prolonged-exposure-and-virtual-reality-exposure-on-suicidal-ideation-in-active-duty-soldiers-an-examination-of-potential-mechanisms
#11
REVIEW
Aaron M Norr, Derek J Smolenski, Greg M Reger
OBJECTIVE: The current study sought to investigate the effects of exposure therapy on suicidal ideation (SI), as well as potential mechanistic pathways of SI reduction among active duty military personnel. METHODS: Active duty army soldiers (N = 162) were recruited from a military base in the U.S. and were enrolled in a randomized clinical trial comparing Prolonged Exposure (PE), Virtual Reality Exposure (VRE), and a wait-list control for the treatment of posttraumatic stress disorder (PTSD) stemming from deployments to Iraq or Afghanistan...
May 12, 2018: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29783075/mir-19a-negatively-regulated-the-expression-of-pten-and-promoted-the-growth-of-ovarian-cancer-cells
#12
Yuhong Wang, Shuzhen Zhao, Lihong Zhu, Quanle Zhang, Yanfang Ren
Ovarian cancer is the most lethal malignancy of the women genital tract. Exploring novel factors involved in the development of ovarian cancer and characterizing the molecular mechanisms by which regulate the tumorigenesis of ovarian cancer are quite necessary. Here, we found that miR-19a was highly expressed in ovarian cancer tissues and cell lines. Overexpression of miR-19a promoted the viability of ovarian cancer cells, while down-regulation of miR-19a inhibited the growth of ovarian cancer cells. To further understand the underlying molecular mechanism of miR-19a in regulating ovarian cancer cell growth, the downstream targets of miR-19a were predicted...
May 18, 2018: Gene
https://www.readbyqxmd.com/read/29783073/methylation-analysis-of-cmtm3-and-dusp1-gene-promoters-in-high-quality-brush-hair-in-the-yangtze-river-delta-white-goat
#13
Wang Qiang, Haiyan Guo, Yongjun Li, Jianfei Shi, Xiuyuan Yin, Jingwen Qu
The Yangtze River delta white goat is the only goat breed that produces high-quality brush hair, which is specifically used in top-grade writing brushes. Previous studies have indicated that the CMTM3 and DUSP1 genes are involved in the growth and cycle of high-quality brush hair, and these genes are thought to be involved in the formation of high-quality brush hair traits. In this study, we investigated the relationship between methylation of CMTM3 and DUSP1 and such traits. The results indicated that the relative expression levels of the CMTM3 and DUSP1 genes were higher in non-high-quality brush hair than in high-quality brush hair...
May 18, 2018: Gene
https://www.readbyqxmd.com/read/29783071/mef2a-regulates-calpain-3-expression-in-l6-myoblasts
#14
Ronghua Wu, Jun Wang, Jian Yao, Zhangji Dong, Yan Liu, Mei Liu
Calpain 3 (Capn3), a skeletal muscle-specific member of the calpain family, executes some non-proteolytic functions besides its role as a Ca2+ -regulated proteolytic enzyme. Previously, we found that changes in Capn3 expression were linearly correlated with the degree of muscular atrophy following reversible sciatic nerve injury and that knockdown of Capn3 gene expression promoted myoblast differentiation. While the regulation of capn3 gene expression is interesting, transcriptional regulation of Capn3 is still unclear...
May 18, 2018: Gene
https://www.readbyqxmd.com/read/29783047/stroma-cell-derived-factor-1-and-connexins-37-and-43-are-preserved-after-vitrification-and-in-vitro-culture-of-goat-ovarian-cortex
#15
Nathalie Jiatsa Donfack, Kele Amaral Alves, Benner Geraldo Alves, Rebeca Magalhães Pedrosa Rocha, Jamily Bezzera Bruno, Marcelo Bertolini, Regiane Rodrigues Dos Santos, Sheyla Farhaydes Souza Domingues, José Ricardo De Figueiredo, Johan Smitz, Ana Paula Ribeiro Rodrigues
This study aimed to evaluate the follicular morphology and development (follicular activation, cell proliferation, and hormone production), as well as the distribution pattern of Connexins 37 and 43 and SDF-1α after vitrification and in vitro culture of goat ovarian tissue. The study involved four experimental groups: fresh control, vitrified control, fresh culture and vitrified culture. The ovarian fragments were vitrified by a solid surface technique using the Ovarian Tissue Cryosystem and subsequently in vitro cultured for 7 days...
May 12, 2018: Theriogenology
https://www.readbyqxmd.com/read/29783019/total-flavonoid-extract-of-epimedium-herb-increases-the-peak-bone-mass-of-young-rats-involving-enhanced-activation-of-the-ac10-camp-pka-creb-pathway
#16
Hui-Rong Xi, Hui-Ping Ma, Fang-Fang Yang, Yu-Hai Gao, Jian Zhou, Yuan-Yuan Wang, Wen-Yuan Li, Cory J Xian, Ke-Ming Chen
ETHNOPHARMACOLOGICAL RELEVANCE: Epimedium sagittatum brevicornum Maxim. is an important traditional Chinese herb that has long been used to promote bone fracture healing and treat osteoporosis. AIM OF THE STUDY: Achieving peak bone mass by adolescence has now been accepted to be fundamental for preventing osteoporosis in adulthood life. This study investigated the possibility of increasing peak bone mass in young rats using the total flavonoid extract of Epimedium herb (TFE)...
May 18, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29783004/-the-thing-that-really-gets-me-is-the-future-symptomatology-in-older-homeless-adults-in-the-hope-home-study
#17
Adam Bazari, Maria Patanwala, Lauren M Kaplan, Colette L Auerswald, Margot B Kushel
CONTEXT: The homeless population is aging. Older homeless adults experience premature development of age-related conditions and an elevated symptom burden. Little is known about symptom experience among older homeless adults. OBJECTIVES: To characterize the experience, understanding, and management of physical, psychological, social (e.g. loneliness), and existential (e.g. regret, loss of dignity) symptoms among older homeless adults. METHODS: We conducted semi-structured interviews from June 2016 through March 2017 with a purposive sample of participants from the HOPE HOME cohort, a longitudinal study of homeless adults ages 50 and older...
May 18, 2018: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/29783002/a-stepwise-approach-to-laparoscopic-enucleation-and-excision-of-retroperitoneal-cysts
#18
Haider Jan, Tina Kapoor, Vishalli Ghai
STUDY OBJECTIVE: Technical video demonstrating a step by step approach to laparoscopic enucleation and excision of retroperitoneal cysts. DESIGN: Technical video (Canadian Task Force classification III). SETTING: Benign Gynecology Department at a University Hospital. INTERVENTION: Laparoscopic enucleation and excision of retroperitoneal cysts. CONCLUSION: Retroperitoneal cysts are rare lesions associated with numerous complications including compression on neighbouring organs, infection, rupture and malignant transformation...
May 18, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29782991/beneficial-and-paradoxical-roles-of-selenium-at-nutritional-levels-of-intake-in-healthspan-and-longevity
#19
REVIEW
Li Zhang, Huawei Zeng, Wen-Hsing Cheng
Accumulation of genome and macromolecule damage is a hallmark of aging, age-associated degeneration, and genome instability syndromes. Although processes of aging are irreversible, they can be modulated by genome maintenance pathways and environmental factors such as diet. Selenium (Se) confers its physiological functions mainly through selenoproteins, but Se compounds and other proteins that incorporate Se nonspecifically also impact optimal health. Bruce Ames proposed that the aging process could be mitigated by a subset of low-hierarchy selenoproteins whose levels are preferentially reduced in response to Se deficiency...
May 18, 2018: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/29782989/nadph-oxidase-2-deletion-enhances-neurogenesis-following-traumatic-brain-injury
#20
Jing Wang, Merry W Ma, Krishnan M Dhandapani, Darrell W Brann
The NADPH oxidase (NOX) enzyme family is a major source of reactive oxygen species (ROS) and contributor to the secondary pathology underlying traumatic brain injury (TBI). However, little is known about how NOX-derived ROS influences the proliferation and cell-fate determination of neural stem/progenitor cells (NSCs/NPCs) following TBI. In the current study, we found that deletion of NOX2 (NOX2-KO) significantly decreases the population of radial glia-like NSCs and neuroblasts but maintains the population of non-radial Sox2 expressing stem cells under physiological (non-injury) conditions...
May 18, 2018: Free Radical Biology & Medicine
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