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Adolescent osteoporosis

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https://www.readbyqxmd.com/read/29129230/prevalence-of-lifestyle-practices-that-might-affect-bone-health-in-relation-to-vitamin-d-status-among-female-saudi-adolescents
#1
Rajaa Al-Raddadi, Suhad Bahijri, Anwar Borai, Zeyad AlRaddadi
BACKGROUND: Prevention of osteoporosis begins in childhood and adolescence, as most bone mass is accumulated during the first 2 decades of life, with 90% to 95% of an adult's bone mineral content being achieved by the end of adolescence. Therefore, targeting modifiable behaviors among adolescents has an important effect on attaining adequate peak bone mass and minimizing risks for future fractures. OBJECTIVES: The aims of this study were to estimate the prevalence of behaviors affecting bone health and vitamin D status and to identify factors associated with vitamin D deficiency among female Saudi adolescents...
January 2018: Nutrition
https://www.readbyqxmd.com/read/29093789/bone-mineral-density-and-physical-performance-of-female-patients-27-years-or-longer-after-surgery-for-adolescent-idiopathic-scoliosis
#2
Tsutomu Akazawa, Toshiaki Kotani, Tsuyoshi Sakuma, Takehide Katogi, Shohei Minami, Hisateru Niki, Yoshiaki Torii, Shigeta Morioka, Sumihisa Orita, Kazuhide Inage, Kazuki Fujimoto, Yasuhiro Shiga, Kazuhisa Takahashi, Seiji Ohtori
Study Design: Retrospective cohort study. Purpose: To assess bone mineral density (BMD) and bone metabolism ≥27 years after surgery in female patients who underwent spinal fusion for adolescent idiopathic scoliosis (AIS) during adolescence and to determine their associations with physical performance. Overview of Literature: There are no studies investigating postsurgical BMD in middle-aged AIS patients. Methods: This study included 23 patients who provided informed consent among 229 female patients with AIS who underwent spinal fusion from 1968 until 1988...
October 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/29061600/global-research-trends-in-spinal-ultrasound-a-systematic-bibliometric-analysis
#3
Xiao Zhai, Jin Cui, Jie Shao, Qijin Wang, Xiao Chen, Xianzhao Wei, Xiaoyi Zhou, Ziqiang Chen, Yushu Bai, Ming Li
BACKGROUND: In recent years, there has been increased interest in the use of ultrasound technology in the evaluation of spinal and paraspinal regions. OBJECTIVE: This study aimed to investigate trends in spinal ultrasound research from 1994 to 2015 and compare the contributions of such research from different countries and authors. STUDY DESIGN: Bibliometric analysis. SETTING: Publications related to spinal ultrasound from 1994 to 2015 were retrieved from the Web of Science database...
October 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/29052784/exercise-and-bone-health-across-the-lifespan
#4
Lívia Santos, Kirsty Jayne Elliott-Sale, Craig Sale
With ageing, bone tissue undergoes significant compositional, architectural and metabolic alterations potentially leading to osteoporosis. Osteoporosis is the most prevalent bone disorder, which is characterised by progressive bone weakening and an increased risk of fragility fractures. Although this metabolic disease is conventionally associated with ageing and menopause, the predisposing factors are thought to be established during childhood and adolescence. In light of this, exercise interventions implemented during maturation are likely to be highly beneficial as part of a long-term strategy to maximise peak bone mass and hence delay the onset of age- or menopause-related osteoporosis...
October 20, 2017: Biogerontology
https://www.readbyqxmd.com/read/29034648/interactive-multimedia-training-in-osteoporosis-prevention-of-female-high-school-students-an-interventional-study
#5
Ladan Zarshenas, Tala Keshavarz, Marzieh Momennasab, Nahid Zarifsanaiey
Given the limitations of traditional teaching methods in the learning process of adolescents, this study was designed to investigate the effects of osteoporosis prevention training through interactive multimedia method on the degree of knowledge and self-efficacy of female high school students. In this interventional study which was conducted in 2016 in Fars province, Iran, 120 high school students were selected through proportional stratified sampling from schools and different classes at first, second, third, and pre-university grades...
August 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/29028268/relationship-between-the-mediterranean-dietary-pattern-and-musculoskeletal-health-in-children-adolescents-and-adults-systematic-review-and-evidence-map
#6
Jean V Craig, Diane K Bunn, Richard P Hayhoe, Will O Appleyard, Elizabeth A Lenaghan, Ailsa A Welch
An understanding of the modifiable effects of diet on bone and skeletal muscle mass and strength over the life course will help inform strategies to reduce age-related fracture risk. The Mediterranean diet is rich in nutrients that may be important for optimal musculoskeletal health. The aim of this systematic review was to investigate the relationship between a Mediterranean diet and musculoskeletal outcomes (fracture, bone density, osteoporosis, sarcopenia) in any age group. Ten electronic databases were searched...
October 1, 2017: Nutrition Reviews
https://www.readbyqxmd.com/read/29017892/muscle-functions-and-bone-strength-are-impaired-in-adolescents-with-type-1-diabetes
#7
Klara Maratova, Ondrej Soucek, Jana Matyskova, Zdenek Hlavka, Lenka Petruzelkova, Barbora Obermannova, Stepanka Pruhova, Stanislava Kolouskova, Zdenek Sumnik
BACKGROUND: Sarcopenia and osteoporosis are among the late complications of type 1 diabetes (T1D) in adults. Whether and to what extent musculoskeletal impairment is present in childhood and adolescence has yet to be determined. The aim of this study was to assess volumetric bone mineral density (BMD) and dynamic muscle function in adolescents with T1D and to assess the clinical and biochemical predictors of their musculoskeletal system. METHODS: Ninety-five children and adolescents (59 boys and 36 girls, mean age 16...
October 7, 2017: Bone
https://www.readbyqxmd.com/read/28982680/chronic-psychosocial-stress-disturbs-long-bone-growth-in-adolescent-mice
#8
S Foertsch, M Haffner-Luntzer, J Kroner, F Gross, K Kaiser, M Erber, S O Reber, A Ignatius
Although a strong association between psychiatric and somatic disorders is generally accepted, little is known regarding the interrelation between mental and skeletal health. While depressive disorders were shown to be strongly associated with osteoporosis and increased fracture risk, evidence from post-traumatic stress disorder (PTSD) patients is less consistent. Therefore, the present study investigated the influence of chronic psychosocial stress on bone using a well-established murine model for PTSD. 7-week-old C57BL/6N mice were subjected to chronic subordinate colony housing (CSC) for 19 days, whereas control mice were singly housed...
October 5, 2017: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/28977339/glucocorticoid-induced-bone-disease-mechanisms-and-importance-in-pediatric-practice
#9
Emanuel Sávio Cavalcanti Sarinho, Verônica Maria Pinho Pessoa Melo
OBJECTIVE: To describe mechanisms by which glucocorticoids cause osteoporosis, with fracture risk, combining this learning with a possible professional behavior change. DATA SOURCES: A systematic search on SciELO, PubMed, Scopus, and Medline databases was carried out for consensus, review articles, including systematic reviews and meta-analysis, which were published in English, between 2000 and 2016. Keywords used on the search were the following: glucocorticoids, fractures, osteoporosis, bone health, vitamin D, children, and adolescents...
April 2017: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
https://www.readbyqxmd.com/read/28830650/basics-of-bone-metabolism-and-osteoporosis-in-common-pediatric-neuromuscular-disabilities
#10
REVIEW
Evren Yaşar, Emre Adigüzel, Mutluay Arslan, Dennis J Matthews
Bone modeling is a process that starts with fetal life and continues during adolescence. Complex factors such as hormones, nutritional and environmental factors affect this process. In addition to these factors, physical conditioning and medications that have toxic effects on bony tissue should be carefully considered in patient follow-up. Osteoporosis is a significant problem in pediatric population because of ongoing growth and development of skeletal system. Two types of osteoporosis are primary and secondary types and children with neuromuscular disabilities constitute a major group with secondary osteoporosis...
August 10, 2017: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/28828163/erythema-multiforme-induced-by-alendronate-sodium-in-a-geriatric-patient-a-case-report-and-review-of-the-literature
#11
José-Alcides de Arruda, Pedro Silva, Márcio-Bruno Amaral, Fernanda Cotta, Renata Avendanho, Ricardo Mesquita
Erythema multiforme is an uncommon acute inflammatory disorder caused by exposure to microbes or drugs. Erythema multiforme minor typically affects only one mucosa and can be associated with symmetrical target skin lesions on the extremities. The disease usually occurs in patients in their 3rd and 4th decade of life, but can also affect children and adolescents. Alendronate sodium has been approved for the prevention and treatment of osteoporosis in postmenopausal women, but is associated with adverse events...
July 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28795004/the-female-athlete-triad-special-considerations-for-adolescent-female-athletes
#12
REVIEW
Kelly A Brown, Aditya V Dewoolkar, Nicole Baker, Colleen Dodich
The number of adolescent girls participating in sports has dramatically increased throughout the last few decades. In the early 1990's, an association between amenorrhea, osteoporosis, and disordered eating was recognized and eventually labeled the 'Female Athlete Triad'. In 1997, the Task Force on Women's Issues of American College of Sports Medicine (ACSM) published a position statement on this triad of conditions that were becoming increasingly more prevalent amongst female athletes. Initially, the 'Female Athlete Triad' was characterized by disordered eating, amenorrhea, and osteoporosis...
July 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28672287/association-between-linear-growth-and-bone-accrual-in-a-diverse-cohort-of-children-and-adolescents
#13
MULTICENTER STUDY
Shana E McCormack, Diana L Cousminer, Alessandra Chesi, Jonathan A Mitchell, Sani M Roy, Heidi J Kalkwarf, Joan M Lappe, Vicente Gilsanz, Sharon E Oberfield, John A Shepherd, Karen K Winer, Andrea Kelly, Struan F A Grant, Babette S Zemel
Importance: Prevention of osteoporosis in adulthood begins with optimizing bone health in early life. The longitudinal association between growth and bone accretion during childhood is not fully understood. Objectives: To assess the acquisition of whole-body (WB) and skeletal site-specific bone mineral content (BMC) relative to linear growth in a healthy, diverse, longitudinal cohort of children, adolescents, and young adults and to test for differences related to sex and African American race...
September 5, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28642855/knowledge-on-osteoporosis-among-nurses
#14
Chan-Ho Park, Young-Kyun Lee, Kyung-Hoi Koo
BACKGROUND: It is crystal clear how important healthcare providers are well-aware of reasonable knowledge on osteoporosis, because they are at the forefront of such management. However, no study has been yet assessed in the knowledge on osteoporosis among healthcare providers particularly in nurse. Therefore, we evaluated the knowledge on osteoporosis of nurses. METHODS: In April 2017, 67 nurses were evaluated using a modified Facts on Osteoporosis Quiz (FOOQ). RESULTS: Although nurses grasped some points of osteoporosis, their knowledge was insufficient concerning effects of weight, physical exercise and calcium intake during adolescence...
May 2017: Journal of Bone Metabolism
https://www.readbyqxmd.com/read/28554377/pharmacological-treatment-options-for-low-bone-mineral-density-and-secondary-osteoporosis-in-anorexia-nervosa-a-systematic-review-of-the-literature
#15
REVIEW
Lauren Robinson, Victoria Aldridge, Emma M Clark, Madhusmita Misra, Nadia Micali
OBJECTIVE: Although there are several evidence-based treatments available to increase Bone Mineral Density (BMD) and reduce fracture risk in aging men and women, there are still uncertainties regarding which treatments are efficacious in reducing lifetime fracture risk in women with Anorexia Nervosa (AN). METHODS: Medline, PsychInfo, Embase and the Cochrane Database were searched for English Language Studies. Inclusion criteria were studies of females of any age with AN who received pharmacological treatment with the primary aim to increase BMD or reduce fracture risk...
July 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28543781/fracture-prospectively-recorded-from-prepuberty-to-young-adulthood-are-they-markers-of-peak-bone-mass-and-strength-in-males
#16
Thierry Chevalley, Jean-Philippe Bonjour, Marie-Claude Audet, Fanny Merminod, Bert van Rietbergen, Rene Rizzoli, Serge Ferrari
Fractures are common in otherwise healthy children and adolescents. They result from trauma of varying severity. Some reflect a greater skeletal fragility. A long-term implication of these fractures is their potentiality to predict adult bone fragility and increased risk of osteoporosis in later life. Using dual-energy X-ray absorptiometry (DXA), high-resolution peripheral quantitative computed tomography (HR-pQCT), and micro-finite element analysis (μFEA) measurements, we previously found in 124 healthy females, followed from the age of 7...
May 24, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28538897/do-you-know-this-syndrome-werner-syndrome
#17
Özlem Bilgiç
Werner syndrome is a rare autosomal recessive disorder, caused by mutations in the WRN gene. Clinical findings include: senile appearance, short stature, grey hair, alopecia, bird-like face, scleroderma-like skin changes, skin ulcers, voice abnormalities, cataracts, osteoporosis, type 2 diabetes mellitus, ischemic heart disease and hypogonadism. The syndrome begins to become apparent in adolescence but it is usually diagnosed in the third or fourth decade of life. Since the patients usually die by the age of 40-50 years related to malignant neoplasms or atherosclerotic complications, they should be closely followed and treated for complications...
March 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28505049/perceived-impairment-in-sports-participation-in-adolescents-with-inflammatory-bowel-diseases-a-preliminary-examination
#18
Jill M Plevinsky, Andrea A Wojtowicz, Natasha Poulopoulos, Kristin L Schneider, Rachel N Greenley
OBJECTIVE: Physical activity is important for adolescents with inflammatory bowel diseases (IBD) given the increased risk of developing osteoporosis and the increased risk of IBD-related complications among those with IBD and obesity. Symptoms like fatigue, abdominal pain, nausea, and frequent bowel movements can interfere with physical activity. Sports participation is an important source of physical activity for adolescents; however, the extent to which IBD interferes with sports participation is unstudied...
May 12, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28502444/nonalcoholic-fatty-liver-disease-in-children-hepatic-and-extrahepatic-complications
#19
REVIEW
Praveen Kumar Conjeevaram Selvakumar, Mohammad Nasser Kabbany, Valerio Nobili, Naim Alkhouri
Nonalcoholic fatty liver disease (NAFLD) is considered the hepatic manifestation of metabolic syndrome and has become the most common form of chronic liver disease in children and adolescents. The histologic spectrum of NAFLD is broad ranging, from the relatively benign form of simple steatosis to the aggressive form of nonalcoholic steatohepatitis, eventually leading to fibrosis and cirrhosis. NAFLD has also been recognized as an independent risk factor for extrahepatic complications, such as cardiovascular disease, type 2 diabetes mellitus, sleep disorders, and osteoporosis...
June 2017: Pediatric Clinics of North America
https://www.readbyqxmd.com/read/28479301/bone-size-and-quality-regulation-concerted-actions-of-mtor-in-mesenchymal-stromal-cells-and-osteoclasts
#20
Hongguang Wu, Zhixiang Wu, Ping Li, Qian Cong, Rongrong Chen, Wenrui Xu, Soma Biswas, Huijuan Liu, Xuechun Xia, Shanshan Li, Weiwei Hu, Zhenlin Zhang, Samy L Habib, Lingli Zhang, Jun Zou, Hongbing Zhang, Weihong Zhang, Baojie Li
The bone size and quality, acquired during adolescent growth under the influence of anabolic hormones, growth factors, and nutrients, determine the height and bone stability and forecast osteoporosis risks in late life. Yet bone size and quality control mechanisms remain enigmatic. To study the roles of mammalian target of rapamycin (mTOR) signaling, sensor of growth factors and nutrients, in bone size and quality regulation, we ablated Tsc1, a suppressor of mTOR, in mesenchymal stromal cells (MSCs), monocytes, or their progenies osteoblasts and osteoclasts...
June 6, 2017: Stem Cell Reports
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