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Eduardo Jaramillo, Daniel Melnick, Juan Carlos Baez, Henry Montecino, Nelson A Lagos, Emilio Acuña, Mario Manzano, Patricio A Camus
The April 1st 2014 Iquique earthquake (MW 8.1) occurred along the northern Chile margin where the Nazca plate is subducted below the South American continent. The last great megathrust earthquake here, in 1877 of Mw ~8.8 opened a seismic gap, which was only partly closed by the 2014 earthquake. Prior to the earthquake in 2013, and shortly after it we compared data from leveled benchmarks, deployed campaign GPS instruments, continuous GPS stations and estimated sea levels using the upper vertical level of rocky shore benthic organisms including algae, barnacles, and mussels...
2017: PloS One
Gabriela Borrayo-Sánchez, Gilberto Pérez-Rodríguez, Olga Georgina Martínez-Montañez, Eduardo Almeida-Gutiérrez, Erick Ramírez-Arias, Joel Estrada-Gallegos, Norma Magdalena Palacios-Jiménez, Martín Rosas-Peralta, Efraín Arizmendi-Uribe, Jesús Arriaga-Dávila
Cardiovascular diseases are a major public health problem because of their they impact on more than 30% of all deaths worldwide. In our country and in the Instituto Mexicano del Seguro Social (IMSS) are also the leading cause of death and the main cause of lost of healthy life years due to disability or premature death. 50% of deaths are premature; most of them are due to acute myocardial infarct. However, the investment for cardiovascular health is poor and there are no comprehensive cares programs focused on the treatment of this diseases or the control of their risk factors...
March 2017: Revista Médica del Instituto Mexicano del Seguro Social
Wojciech Streciwilk, Alessio Terenzi, Rainer Misgeld, Corazon Frias, Peter G Jones, Aram Prokop, Bernhard K Keppler, Ingo Ott
Naphthalimide-based N-heterocyclic carbene (NHC) complexes of the type [(1,5-cyclooctadiene)(NHC)RhCl)] (4 a-c), [(p-cymene)(NHC)RuCl2 )] (5 a-c), and [(NHC)CuBr] (6 a-c) were synthesized and investigated as antiproliferative agents that target DNA. The cytotoxic effects were largely driven by the naphthalimide structure, which is a DNA-intercalating moiety. Regarding the metal center, the highest activities were observed with the rhodium complexes, and cytotoxic activity was significantly lower for the ruthenium derivatives...
December 20, 2016: ChemMedChem
Mya Myat Ngwe Tun, Rohitha V Muthugala, Nguyen Thi Thu Thuy, Pham Hoai Linh Ly, Le Thi Hien Thu, Dang Thi Dinh, Nguyen Viet Hoang, Le Thi Quynh Mai, Meng Ling Moi, Corazon C Buerano, Kouichi Morita, Futoshi Hasebe
Acute encephalitis syndrome (AES) is associated with high morbidity and mortality, and affects both children and adults. The main etiologic agent is Japanese encephalitis virus (JEV), however there are also reports on Dengue virus (DENV) encephalitis cases. The objectives of this paper were to determine the proportion of encephalitic patients due to JEV during the 2014 outbreak in Son La Province in Vietnam and to find the association of DENV in non-JEV viral encephalitis cases. Out of 90 patients, 6 (6.7%) were positive for anti-JEV IgM, 5 (5...
October 31, 2016: Japanese Journal of Infectious Diseases
Mya Myat Ngwe Tun, Aung Kyaw Kyaw, Nader Makki, Rohitha Muthugala, Takeshi Nabeshima, Shingo Inoue, Daisuke Hayasaka, Meng Ling Moi, Corazon C Buerano, Saw Myat Thwe, Kyaw Zin Thant, Kouichi Morita
In 2013 in Myanmar, dengue epidemic occurred with 20,255 cases including 84 deaths. This study aimed to determine the serological and molecular characteristics of dengue virus (DENV) infection among children with clinical diagnosis of dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS) during this period. Single acute serum samples were collected from 300 children in Mandalay Children Hospital, Mandalay, Myanmar. Out of the 300 children, 175 (58.3%) and 183 (61%) were positive for anti-dengue IgM and anti-dengue IgG, respectively...
September 2016: Infection, Genetics and Evolution
Jane Hamilton, May Maxime Corazon Yaneza, William Andrew Clement, Haytham Kubba
AIM: Airway disorders are common in children with Down's syndrome. We report the findings on airway endoscopy in a birth cohort of children from a well-defined geographical area, in order to estimate true population prevalence of airway problems in children with Down's syndrome. METHOD: Retrospective case note review over a 20-year period between 1993 and 2013 for all children in Greater Glasgow born with Down's syndrome, identified through the hearing surveillance programme...
February 2016: International Journal of Pediatric Otorhinolaryngology
Meredith P Fort, Sandra Murillo, Erika López, Ana Laura Dengo, Nadia Alvarado-Molina, Indira de Beausset, Maricruz Castro, Liz Peña, Manuel Ramírez-Zea, Homero Martínez
BACKGROUND: Previous healthy lifestyle interventions based on the Salud para Su Corazón curriculum for Latinos in the United States, and a pilot study in Guatemala, demonstrated improvements in patient knowledge, behavior, and clinical outcomes for adults with hypertension. This article describes the implementation of a healthy lifestyle group education intervention at the primary care health center level in the capital cities of Costa Rica and Chiapas, Mexico for patients with hypertension and/or type 2 diabetes and presents impact evaluation results...
December 28, 2015: BMC Health Services Research
M M C Yaneza, K Hunter, S Irwin, H Kubba
OBJECTIVES: To report the prevalence of hearing problems and the hearing sequelae in school-aged children with trisomy 21 in a longitudinal study. DESIGN: All children with trisomy 21 were identified via schools, community-based child development centres, general practitioners, or the universal newborn hearing screen. Audiological data and otorhinolaryngological problems were prospectively entered in to the Audiological Surveillance Programme database from each visit...
December 2016: Clinical Otolaryngology
Héctor G Balcázar, Hendrik D de Heer, Sherrie Wise Thomas, Alisha Redelfs, E Lee Rosenthal, Ximena Burgos, Maria O Duarte
INTRODUCTION: Limited research has documented interventions aimed at promoting use of existing recreational community resources among underserved populations. This study (HEART [Health Education Awareness Research Team] Phase 2) reports findings of an intervention (Mi Corazón Mi Comunidad) where community health workers facilitated use of diet and exercise programming at local recreational facilities among Mexican American border residents. The aim was to evaluate overall attendance rates and to assess which factors predicted higher attendance...
May 2016: Health Promotion Practice
Charissa Fay Corazon Borja-Tabora, Cecilia Montalban, Ziad A Memish, Dominique Boutriau, Devayani Kolhe, Jacqueline M Miller, Marie Van der Wielen
BACKGROUND: Long-term protection against meningococcal disease is associated with persistence of post-vaccination antibodies at protective levels. We evaluated the bactericidal antibody persistence and safety of the quadrivalent meningococcal serogroups A, C, W and Y tetanus-toxoid conjugate vaccine (MenACWY-TT) and the meningococcal polysaccharide serogroups A, C, W, and Y vaccine (MenACWY-PS) up to 5 years post-vaccination. METHODS: This phase IIb, open, randomized, controlled study conducted in the Philippines and Saudi Arabia consisted of a vaccination phase and a long-term persistence phase...
October 6, 2015: BMC Infectious Diseases
José López-Sendón, José Ramón González-Juanatey, Fausto Pinto, José Cuenca Castillo, Lina Badimón, Regina Dalmau, Esteban González Torrecilla, José Ramón López-Mínguez, Alicia M Maceira, Domingo Pascual-Figal, José Luis Pomar Moya-Prats, Alessandro Sionis, José Luis Zamorano
Cardiology practice requires complex organization that impacts overall outcomes and may differ substantially among hospitals and communities. The aim of this consensus document is to define quality markers in cardiology, including markers to measure the quality of results (outcomes metrics) and quality measures related to better results in clinical practice (performance metrics). The document is mainly intended for the Spanish health care system and may serve as a basis for similar documents in other countries...
November 2015: Revista Española de Cardiología
Minh Huong Phu Ly, Yuki Takamatsu, Takeshi Nabeshima, Linh Ly Pham Hoai, Hang Pham Thi, Dinh Dang Thi, Ngoc Linh Nguyen, Thu Thuy Nguyen Thi, Quynh Mai Le Thi, Corazon C Buerano, Kouichi Morita, Futoshi Hasebe
Dengue encephalitis (DE) is characterized as unusual presentation of dengue infection. Despite the reports that DE accounts for only 1-5% of dengue cases, this disease tends to be increasingly reported to threaten global human health throughout dengue endemic areas particularly in Southeast Asia. The molecular information of clinically characterized, neurotropic dengue virus (DENV) in human beings is extremely scarce despite it playing an important role in deciphering the pathogenesis of dengue-related neurological cases...
September 2015: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
Gayvelline C Calacal, Dame Loveliness T Apaga, Jazelyn M Salvador, Joseph Andrew D Jimenez, Ludivino J Lagat, Renato Pio F Villacorta, Maria Cecilia F Lim, Raquel D R Fortun, Francisco A Datar, Maria Corazon A De Ungria
The capability of DNA laboratories to perform genotyping procedures from post-mortem remains, including those that had undergone putrefaction, continues to be a challenge in the Philippines, a country characterized by very humid and warm conditions all year round. These environmental conditions accelerate the decomposition of human remains that were recovered after a disaster and those that were left abandoned after a crime. When considerable tissue decomposition of human remains has taken place, there is no other option but to extract DNA from bone and/or teeth samples...
November 2015: Forensic Science International. Genetics
Fuxun Yu, Yanhua Du, Xueyong Huang, Hong Ma, Bianli Xu, Ferdinard Adungo, Daisuke Hayasaka, Corazon C Buerano, Kouichi Morita
BACKGROUND: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging disease that was first reported in China in 2011. It is caused by SFTS virus (SFTSV) which is a member of the Phlebovirus genus in the Bunyaviridae family. SFTSV has been classified as a BSL3 pathogen. There is a need to develop safe and affordable serodiagnostic methods for proper clinical management of infected patients. METHODS: The full length nucleocapsid (N) gene of SFTSV Yamaguchi strain was amplified by RT-PCR and cloned to an expression vector pQE30...
2015: Virology Journal
Hendrik Dirk de Heer, Hector G Balcazar, Sherrie Wise, Alisha H Redelfs, E Lee Rosenthal, Maria O Duarte
BACKGROUND: Community resources (parks, recreational facilities) provide opportunities for health promotion, but little is known about how to promote utilization of these resources and their impact on cardiovascular disease risk (CVD). METHODS: This cohort study evaluated the impact of an intervention called Mi Corazon Mi Comunidad (MiCMiC), which consisted of promoting use of community physical activity and nutrition resources by Promotoras de Salud/Community Health Workers...
2015: Frontiers in Public Health
Christian Prinz, Elena Vasyutina, Gregor Lohmann, Alexandra Schrader, Steffen Romanski, Christoph Hirschhäuser, Petra Mayer, Corazon Frias, Carmen D Herling, Michael Hallek, Hans-Günther Schmalz, Aram Prokop, Dimitrios Mougiakakos, Marco Herling
BACKGROUND: Redox stress is a hallmark of the rewired metabolic phenotype of cancer. The underlying dysregulation of reactive oxygen species (ROS) is interconnected with abnormal mitochondrial biogenesis and function. In chronic lymphocytic leukemia (CLL), elevated ROS are implicated in clonal outgrowth and drug resistance. The pro-survival oncogene T-cell leukemia 1 (TCL1) is causally linked to the high threshold towards classical apoptosis in CLL. We investigated how aberrant redox characteristics and bioenergetics of CLL are impacted by TCL1 and if this is therapeutically exploitable...
2015: Molecular Cancer
Kristin Keller, Santiago Rodríguez López, Margarita M Carmenate Moreno
The study aims to evaluate the association between abdominal obesity with meal intake behaviour such as having a forenoon meal, having an afternoon meal and snacking. This cross-sectional study includes n = 1314 participants aged 20-79 who were interviewed during the Cardiac health "Semanas del Corazon" events in four Spanish cities (Madrid, Las Palmas, Seville and Valencia) in 2008. Waist circumference, weight and height were assessed to determine abdominal obesity (waist circumference: ≥88 cm in women and ≥102 cm in men) and BMI, respectively...
September 2015: Appetite
Erick J Rendón-Ramirez, Alejandro Ortiz-Stern, Corazon Martinez-Mejia, Mario C Salinas-Carmona, Adrian Rendon, Viviana L Mata-Tijerina, Adrian G Rosas-Taraco
There is a strong interest in finding adequate biomarkers to aid in the diagnosis and prognosis of influenza A (H1N1)pdm09 virus infection. In this study, serum levels of inflammatory cytokines and laboratory markers were evaluated to assess their usefulness as biomarkers of influenza A (H1N1)pdm09 and their association with fatal cases. Serum samples of consecutive patients with a clinical presentation suggestive of influenza A (H1N1)pdm09 and progression to sepsis were evaluated. Serum inflammatory cytokines and routine laboratory tests were performed and correlated with positivity for influenza A (H1N1)pdm09 influenza by real time reverse transcription polymerase chain reaction and the results of three clinical severity scores (Sequential Organ Failure Assessment [SOFA], CURB-65, and Acute Physiology and Chronic Health Evaluation II [APACHE II])...
June 2015: Viral Immunology
Tatsuhiko Tsukakoshi, Josaia Samuela, Eric V Rafai, Uraia Rabuatoka, Sumihisa Honda, Yasuhiko Kamiya, Corazon C Buerano, Kouichi Morita
BACKGROUND: In Fiji, hepatitis B (HB) vaccine was introduced into childhood immunization program in 1989 and has been administered as a pentavalent since 2006. This study aimed to: (i) survey and examine the extent to which HB infection continue to occur in children, adolescents and adults in Fiji, and (ii) determine HB coverage rates and timeliness of vaccine administration to children. METHODS: Serum samples of children, adolescents and adults (aged 6 months to <5 years, 16-20 years, and 21-49 years, respectively) collected between 2008-2009 were tested for serologic markers of HB virus infection namely, HB surface antigen (HBsAg), anti-HBs and anti-HB core antigen (anti-HBc)...
2015: Virology Journal
Jae Joseph Russell Beltran Rodriguez, Jazelyn M Salvador, Gayvelline C Calacal, Rita P Laude, Maria Corazon A De Ungria
We characterized diversity and forensic descriptive parameters of 23 autosomal STR loci (CSF1PO, D13S317, D16S539, D5S818, D7S820, TPOX, D18S51, D21S11, D3S1358, D8S1179, FGA, TH01, vWA, D1S1656, D10S1248, D12S391, D2S441, D22S1045, D19S433, D2S1338, D6S1043, Penta D and Penta E) among 167 unrelated Filipinos. The most variable autosomal STR loci observed is Penta E (observed heterozygosity: 0.9222, match probability: 0.0167). Results reveal matching probability of 8.21×10(-28) for 23 autosomal STR loci. This dataset for the Philippine population may now be used in evaluating the weight of DNA evidence for forensic applications such as in human identification, parentage/kinship testing, and interpretation of DNA mixtures...
July 2015: Legal Medicine
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