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https://www.readbyqxmd.com/read/28571893/selective-serotonin-reuptake-inhibitors-and-cataract-risk-a-case-control-analysis
#1
Claudia Becker, Susan S Jick, Christoph R Meier
PURPOSE: Use of selective serotonin reuptake inhibitors (SSRIs) has been associated with an increased cataract risk. We aimed to assess cataract risk after exposure to SSRI or to other antidepressant drugs in a large electronic primary care database. DESIGN: Case-control study. PARTICIPANTS: The study population was derived from the UK-based Clinical Practice Research Datalink (CPRD). We included patients with first-time cataract aged ≥40 years between 1995 and 2015 and an equal number of cataract-free controls matched on age, sex, general practice, date of cataract recording (i...
May 29, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28536845/bariatric-surgery-in-septuagenarians-a-comparison-with-60%C3%A2-year-olds
#2
Chetan Parmar, Kamal K Mahawar, William R J Carr, Norbert Schroeder, Shlok Balupuri, Peter K Small
INTRODUCTION: There is reluctance amongst many healthcare professionals to offer bariatric surgery to septuagenarians. There is only one study in the scientific literature specifically describing any experience with this group of patients and none that compares the outcomes in this group with younger patients. METHODS: We retrospectively examined our prospective database to identify all those who were >70 years old at the time of bariatric surgery. This group was then compared with a matched (for sex, body mass index, surgical procedure, and time of surgery) cohort of younger (<60 year old) patients...
May 23, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28536104/development-and-validation-of-qrisk3-risk-prediction-algorithms-to-estimate-future-risk-of-cardiovascular-disease-prospective-cohort-study
#3
Julia Hippisley-Cox, Carol Coupland, Peter Brindle
Objectives To develop and validate updated QRISK3 prediction algorithms to estimate the 10 year risk of cardiovascular disease in women and men accounting for potential new risk factors.Design Prospective open cohort study.Setting General practices in England providing data for the QResearch database.Participants 1309 QResearch general practices in England: 981 practices were used to develop the scores and a separate set of 328 practices were used to validate the scores. 7.89 million patients aged 25-84 years were in the derivation cohort and 2...
May 23, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28528130/increased-body-mass-index-is-a-risk-factor-for-end-stage-renal-disease-in-the-chinese-singapore-population
#4
Quan-Lan Jasmine Lew, Tazeen Hasan Jafar, Mohammad Talaei, Aizhen Jin, Khuan Yew Chow, Jian-Min Yuan, Woon-Puay Koh
The relationship between body mass index (BMI) and end-stage renal disease (ESRD) is confounded by co-morbidities associated with both conditions. Furthermore, the association at low range BMI is controversial. We studied this association in the Singapore Chinese Health Study, a population-based prospective cohort that recruited Singaporean Chinese men and women 45-74 years of age from 1993 to 1998. Self-reported weight, height, lifestyle factors, usual diet, and medical history were collected via an interviewer-administered questionnaire...
May 18, 2017: Kidney International
https://www.readbyqxmd.com/read/28526434/a-systematic-review-of-portomesenteric-vein-thrombosis-after-sleeve-gastrectomy
#5
Osama Shaheen, Jacqueline Siejka, Bala Thatigotla, Dang Tuan Pham
BACKGROUND: Portomesenteric vein thrombosis (PMVT) is considered an uncommon complication in general surgery; nevertheless, with the growing popularity of sleeve gastrectomy (SG) as a bariatric procedure we have seen an increase in the occurrence of this complication. OBJECTIVES: To elucidate the question if it is a procedure-related complication and explore the modalities of prevention and treatment of this complication, a systematic review of available literature regarding PMVT events after SG was conducted...
March 27, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28486480/exposure-to-preeclampsia-in-utero-affects-growth-from-birth-to-late-childhood-dependent-on-child-s-sex-and-severity-of-exposure-follow-up-of-a-nested-case-control-study
#6
Kristine Kjer Byberg, Knut Øymar, Geir Egil Eide, Michele R Forman, Pétur Benedikt Júlíusson
BACKGROUND AND OBJECTIVE: An adverse intrauterine environment may affect offspring growth and development. Our aim was to explore whether preeclampsia (PE) exposure in utero influences growth from birth to 13 years. METHODS: In a nested case-control study, 229 children were exposed to PE (mild/moderate: n = 164, severe: n = 54) and 385 were unexposed. Length/height and weight were abstracted from records at birth, 3 and 6 months, 1 and 4 years, and measured along with waist circumference and skinfolds at follow-up at 11/12 (girls/boys) and 13 years (both sexes)...
2017: PloS One
https://www.readbyqxmd.com/read/28456438/accumulated-exposure-to-unemployment-is-related-to-impaired-glucose-metabolism-in-middle-aged-men-a-follow-up-of-the-northern-finland-birth-cohort-1966
#7
Nina Rautio, Tuulia Varanka-Ruuska, Eeva Vaaramo, Saranya Palaniswamy, Rozenn Nedelec, Jouko Miettunen, Jaro Karppinen, Juha Auvinen, Marjo-Riitta Järvelin, Sirkka Keinänen-Kiukaanniemi, Sylvain Sebert, Leena Ala-Mursula
AIMS: We explored whether registered unemployment is associated with impaired glucose metabolism in general population. METHODS: Based on Northern Finland Birth Cohort 1966 at 46 years, we analyzed the oral glucose tolerance tests of 1970 men and 2544 women in relation to their preceding three-year employment records in three categories of unemployment exposure: no (employed), low (≤1-year) and high exposure (>1-year). RESULTS: Among men, pre-diabetes was found in 19...
April 26, 2017: Primary Care Diabetes
https://www.readbyqxmd.com/read/28421186/cost-description-and-comparative-cost-efficiency-of-post-exposure-prophylaxis-and-canine-mass-vaccination-against-rabies-in-n-djamena-chad
#8
Rolande Mindekem, Monique Sarah Lechenne, Kemdongarti Service Naissengar, Assandi Oussiguéré, Bidjeh Kebkiba, Daugla Doumagoum Moto, Idriss Oumar Alfaroukh, Laurent Tinoanga Ouedraogo, Sahidou Salifou, Jakob Zinsstag
Rabies claims approximately 59,000 human lives annually and is a potential risk to 3.3 billion people in over 100 countries worldwide. Despite being fatal in almost 100% of cases, human rabies can be prevented by vaccinating dogs, the most common vector, and the timely administration of post-exposure prophylaxis (PEP) to exposed victims. For the control and prevention of human rabies in N'Djamena, the capital city of Chad, a free mass vaccination campaign for dogs was organized in 2012 and 2013. The campaigns were monitored by parallel studies on the incidence of canine rabies based on diagnostic testing of suspect animals and the incidence of human bite exposure recorded at selected health facilities...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28406962/ethnic-differences-in-association-of-high-body-mass-index-with-early-onset-of-type-1-diabetes-arab-ethnicity-as-case-study
#9
Arshad M Channanath, Naser Elkum, Dalia Al-Abdulrazzaq, Jaakko Tuomilehto, Azza Shaltout, Thangavel Alphonse Thanaraj
OBJECTIVE: The "accelerator hypothesis" predicts early onset of Type 1 diabetes (T1D) in heavier children. Studies testing direction of correlation between body mass index (BMI) and age at onset of T1D in different continental populations have reported differing results-inverse, direct, and neutral. Evaluating the correlation in diverse ethnic populations is required to generalize the accelerator hypothesis. METHODS: The study cohort comprised 474 Kuwaiti children of Arab ethnicity diagnosed with T1D at age 6 to 18 years during 2011-2013...
2017: PloS One
https://www.readbyqxmd.com/read/28360235/venous-thromboembolism-in-adults-screened-for-sickle-cell-trait-a-population-based-cohort-study-with-nested-case-control-analysis
#10
Iain Little, Yana Vinogradova, Elizabeth Orton, Joe Kai, Nadeem Qureshi
OBJECTIVE: To determine whether sickle cell carriers ('sickle cell trait') have an increased risk of venous thromboembolism (VTE). DESIGN: Cohort study with nested case-control analysis. SETTING: General population with data from 609 UK general practices in the Clinical Practice Research Datalink (CPRD). PARTICIPANTS: All individuals registered with a CPRD general practice between 1998 and 2013, with a medical record of screening for sickle cell between 18 and 75 years of age...
March 29, 2017: BMJ Open
https://www.readbyqxmd.com/read/28346362/nutrition-assessment-of-b-vitamins-in-highly-active-and-sedentary-women
#11
Kathleen Woolf, Nicole L Hahn, Megan M Christensen, Amanda Carlson-Phillips, Christine M Hansen
BACKGROUND: Female athletes and active women require adequate nutrition for optimal health and performance. Nutrition assessments are needed to identify potential nutrients of concern. Folate, vitamin B6, and vitamin B12 function in important pathways used during physical activity and female athletes may be at risk for poor status of these micronutrients. This cross-sectional study described a comprehensive nutrition assessment of the B-vitamins (folate, vitamin B6, and vitamin B12) using both dietary (food and dietary supplements) and biochemical assessments among highly active and sedentary women...
March 26, 2017: Nutrients
https://www.readbyqxmd.com/read/28197222/anomalous-systemic-arterial-supply-of-pulmonary-sequestration-in-adult-patients
#12
Xiaomeng Hou, Ji Li, Jing Li, Baiqiang Cai
OBJECTIVES: This study described the characteristics of the systemic arterial supply of pulmonary sequestration (PS) in an attempt to better distinguish PS from other acquired lesions. METHODS: We identified 25 patients hospitalized at the Peking Union Medical College Hospital during January 2013 to December 2015 with the assistance of medical catalogers. Twenty-three patients with a definite diagnosis of "pulmonary sequestration" clinically or pathologically were included in the study...
January 2017: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/28173709/characteristics-of-patients-seen-by-visiting-psychiatrists-through-medicare-in-a-rural-community-mental-health-service-with-an-established-telemedicine-service
#13
Niranjan Bidargaddi, Geoffrey Schrader, David Smith, Dean Carson, Jörg Strobel
OBJECTIVE: We aimed to determine characteristics of patients receiving Medicare-funded face-to-face consultations by psychiatrists in a rural service with an established telemedicine service. METHODS: For this study, 55 case-managed patients from four rural community mental health teams in South Australia provided information through questionnaires regarding psychological symptoms, quality of life, body mass index (BMI) and gave access to their Medicare data. RESULTS: In a logistic regression, it was found that being younger was more likely associated with a Medicare psychiatric consultation ( p<0...
June 2017: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/28160338/h1-antihistamine-refractory-chronic-spontaneous-urticaria-it-s-worse-than-we-thought-first-results-of-the-multicenter-real-life-aware-study
#14
M Maurer, P Staubach, U Raap, G Richter-Huhn, A Bauer, F Ruëff, T Jakob, A S Yazdi, V Mahler, N Wagner, U Lippert, U Hillen, A Schwinn, M Pawlak, N Behnke, K Chaouche, N Chapman-Rothe
BACKGROUND: Most data on chronic spontaneous urticaria (CSU) originate from highly selected patient populations treated at specialized centres. Little is known about CSU patient characteristics and the burden of CSU in routine clinical practice. AWARE (A World-wide Antihistamine-Refractory chronic urticaria patient Evaluation) is an ongoing global study designed to assess chronic urticaria in the real-life setting. OBJECTIVE: To describe the baseline characteristics of the first 1539 German AWARE patients with H1-antihistamine-refractory CSU...
May 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28151767/increasing-incidence-and-altered-presentation-in-a-population-based-study-of-pediatric-celiac-disease-in-north-america
#15
Eyad Almallouhi, Katherine S King, Bhavisha Patel, Chung Wi, Young J Juhn, Joseph A Murray, Imad Absah
OBJECTIVES: Celiac disease (CD) is a common immune-mediated disorder that affects up to 1% of the general population. Recent reports suggest that the incidence of CD has reached a plateau in many countries. We aim to study the incidence and altered presentation of childhood CD in a well-defined population. METHODS: Using the Rochester Epidemiology Project, we retrospectively reviewed Mayo Clinic and Olmsted Medical Center medical records from January 1994 to December 2014...
February 1, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28099594/diagnosis-and-underdiagnosis-of-comorbidities-in-psoriasis-patients-need-for-a-multidisciplinary-approach
#16
Gleison Vieira Duarte, Maria de Fátima S P de Oliveira, Ivonise Follador, Thadeu Santo Silva, Edgar Marcelino de Carvalho
BACKGROUND: Psoriasis is an immune-mediated disease that manifests predominantly in the skin, although systemic involvement may also occur. Although associated comorbidities have long been recognized and despite several studies indicating psoriasis as an independent risk factor for cardiovascular events, little has been done in general medical practice regardind screening. In the United States, less than 50% of clinicians are aware of these recommendations. OBJECTIVE: To identify the prevalence of these comorbidities in 296 patients followed up at a university dermatology clinic...
November 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28028944/a-comparison-of-two-approaches-to-laparoscopic-adrenalectomy-lateral-transperitoneal-versus-posterior-retroperitoneal-approach
#17
COMPARATIVE STUDY
Magda Marek-Safiejko, Kamil Safiejko, Jerzy Łukaszewicz, Jacek Dadan, Robert J Ładny, Robert Kozłowski, Piotr Wojskowicz, Piotr Myśliwiec
BACKGROUND: Laparoscopic adrenalectomy is the gold standard for the surgical treatment of benign adrenal masses. It is most commonly performed using the lateral transperitoneal approach (LTA) and the posterior retroperitoneal approach (PRA). The choice of the method depends on contraindications for a particular approach in an individual case and surgical experience. The objective of the article is to compare two approaches, LTA and PRA, in view of our own experience and literature review...
September 2016: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/27998654/tree-ring-based-chronology-of-hydro-geomorphic-processes-as-a-fundament-for-identification-of-hydro-meteorological-triggers-in-the-hrub%C3%A3-jesen%C3%A3-k-mountains-central-europe
#18
Radek Tichavský, Karel Šilhán, Radim Tolasz
Hydro-geomorphic processes have significantly influenced the recent development of valley floors, river banks and depositional forms in mountain environments, have caused considerable damage to manmade developments and have disrupted forest management. Trees growing along streams are affected by the transported debris mass and provide valuable records of debris flow/flood histories in their tree-ring series. Dendrogeomorphic approaches are currently the most accurate methods for creating a chronology of the debris flow/flood events in forested catchments without any field-monitoring or a stream-gauging station...
February 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/27993462/complex-medial-meniscus-tears-are-associated-with-a-biconcave-medial-tibial-plateau
#19
F Alan Barber, Mark H Getelman, Kathy L Berry
PURPOSE: To determine whether an association exists between a biconcave medial tibial plateau and complex medial meniscus tears. METHODS: A consecutive series of stable knees undergoing arthroscopy were evaluated retrospectively with the use of preoperative magnetic resonance imaging (MRI), radiographs, and arthroscopy documented by intraoperative videos. Investigators independently performed blinded reviews of the MRI or videos. Based on the arthroscopy findings, medial tibial plateaus were classified as either biconcave or not biconcave...
December 16, 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/27916927/vitamin-b12-status-among-pregnant-women-in-the-uk-and-its-association-with-obesity-and-gestational-diabetes
#20
Nithya Sukumar, Hema Venkataraman, Sean Wilson, Ilona Goljan, Selvin Selvamoni, Vinod Patel, Ponnusamy Saravanan
BACKGROUND: To evaluate vitamin B12 and folate status in pregnancy and their relationship with maternal obesity, gestational diabetes mellitus (GDM), and offspring birthweight. METHODS: A retrospective case-control study of 344 women (143 GDM, 201 no-GDM) attending a district general hospital and that had B12 and folate levels measured in the early 3rd trimester was performed. Maternal history including early pregnancy body mass index (BMI) and neonatal data (birthweight, sex, and gestational age) was recorded for all subjects...
December 1, 2016: Nutrients
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