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https://www.readbyqxmd.com/read/28341610/differential-effects-of-social-and-novelty-enrichment-on-individual-differences-in-impulsivity-and-behavioral-flexibility
#1
Maya Zhe Wang, Andrew T Marshall, Kimberly Kirkpatrick
Early life experience profoundly impacts behavior and cognitive functions in rats. The present study investigated how the presence of conspecifics and/or novel objects, could independently influence individual differences in impulsivity and behavioral flexibility. Twenty-four rats were reared in an isolated condition, an isolated condition with a novel object, a pair-housed social condition, or a pair-housed social condition with a novel object. The rats were then tested on an impulsive choice task, a behavioral flexibility task, and an impulsive action task...
March 21, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28328259/follow-up-study-on-fetal-ct-radiation-dose-in-japan-validating-the-decrease-in-radiation-dose
#2
Osamu Miyazaki, Hideaki Sawai, Takahiro Yamada, Jun Murotsuki, Gen Nishimura
OBJECTIVE: In 2011, we collected data on fetal CT radiation dose to determine the diagnostic reference level (DRL); however, continuous evaluation of the DRL is necessary. The hypothesis of this study is that the fetal CT radiation dose has decreased, and we predict a widespread use of iterative reconstruction (IR). We also predict that the national decrease in exposure is because of the DRL reported as a result of the previous national study. MATERIALS AND METHODS: Various testing protocols from each site were summarized as part of the study results...
April 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28318637/impact-of-multiple-en-face-image-averaging-on-quantitative-assessment-from-optical-coherence-tomography-angiography-images
#3
Akihito Uji, Siva Balasubramanian, Jianqin Lei, Elmira Baghdasaryan, Mayss Al-Sheikh, SriniVas R Sadda
PURPOSE: To investigate the impact of multiple en face image averaging on quantitative measurements of the retinal microvasculature using optical coherence tomography angiography (OCTA). DESIGN: Prospective, observational, cross-sectional case series. PARTICIPANTS: Twenty-one healthy individuals with normal eyes. METHODS: Macular OCTA images were acquired from all participants using the Zeiss Cirrus 5000 with Angioplex OCTA software (Carl Zeiss Meditec, Dublin, CA)...
March 16, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28301651/quantification-of-retinal-microvascular-density-in-optical-coherence-tomographic-angiography-images-in-diabetic-retinopathy
#4
Mary K Durbin, Lin An, Nathan D Shemonski, Mário Soares, Torcato Santos, Marta Lopes, Catarina Neves, Jose Cunha-Vaz
Importance: Quantitative measurements based on optical coherence tomographic angiography (OCTA) may have value in managing diabetic retinopathy (DR), but there is limited information on the ability of OCTA to distinguish eyes with DR. Objective: To evaluate the ability of measurements of retinal microvasculature using OCTA to distinguish healthy eyes from eyes with DR. Design, Setting, and Participants: In this prospective cross-sectional study, OCTA was used to examine the eyes of participants with type 2 diabetes with or without DR and the eyes of participants without diabetes from September 17, 2015, to April 6, 2016...
March 16, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28269391/design-and-validation-of-a-wearable-drl-less-eeg-using-a-novel-fully-reconfigurable-architecture
#5
Ruhi Mahajan, Bashir I Morshed, Gavin M Bidelman
The conventional EEG system consists of a driven-right-leg (DRL) circuit, which prohibits modularization of the system. We propose a Lego-like connectable fully reconfigurable architecture of wearable EEG that can be easily customized and deployed at naturalistic settings for collecting neurological data. We have designed a novel Analog Front End (AFE) that eliminates the need for DRL while maintaining a comparable signal quality of EEG. We have prototyped this AFE for a single channel EEG, referred to as Smart Sensing Node (SSN), that senses brain signals and sends it to a Command Control Node (CCN) via an I2C bus...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28247587/establishment-of-institutional-diagnostic-reference-level-for-computed-tomography-with-automated-dose-tracking-software
#6
Chong R Liang, Priscilla X H Chen, Jeevesh Kapur, Michael K L Ong, Swee T Quek, Subhash C Kapur
INTRODUCTION: The aim of this study was to establish institutional diagnostic reference levels (DRLs) by summarising doses collected across the five computed tomography (CT) system in our institution. METHODS: CT dose data of 15940 patients were collected retrospectively from May 2015 to October 2015 in five institutional scanners. The mean, 75th percentile and 90th percentile of the dose spread were calculated according to anatomic region. The common CT examinations such as head, chest, combined abdomen/pelvis (A/P), and combined chest/abdomen/pelvis (C/A/P) were reviewed...
March 1, 2017: Journal of Medical Radiation Sciences
https://www.readbyqxmd.com/read/28227634/design-and-validation-of-a-wearable-drl-less-eeg-using-a-novel-fully-reconfigurable-architecture
#7
Ruhi Mahajan, Bashir I Morshed, Gavin M Bidelman, Ruhi Mahajan, Bashir I Morshed, Gavin M Bidelman, Bashir I Morshed, Ruhi Mahajan, Gavin M Bidelman
The conventional EEG system consists of a driven-right-leg (DRL) circuit, which prohibits modularization of the system. We propose a Lego-like connectable fully reconfigurable architecture of wearable EEG that can be easily customized and deployed at naturalistic settings for collecting neurological data. We have designed a novel Analog Front End (AFE) that eliminates the need for DRL while maintaining a comparable signal quality of EEG. We have prototyped this AFE for a single channel EEG, referred to as Smart Sensing Node (SSN), that senses brain signals and sends it to a Command Control Node (CCN) via an I(2)C bus...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28221093/u-s-diagnostic-reference-levels-and-achievable-doses-for-10-adult-ct-examinations
#8
Kalpana M Kanal, Priscilla F Butler, Debapriya Sengupta, Mythreyi Bhargavan-Chatfield, Laura P Coombs, Richard L Morin
Purpose To develop diagnostic reference levels (DRLs) and achievable doses (ADs) for the 10 most common adult computed tomographic (CT) examinations in the United States as a function of patient size by using the CT Dose Index Registry. Materials and Methods Data from the 10 most commonly performed adult CT head, neck, and body examinations from 583 facilities were analyzed. For head examinations, the lateral thickness was used as an indicator of patient size; for neck and body examinations, water-equivalent diameter was used...
February 21, 2017: Radiology
https://www.readbyqxmd.com/read/28142349/three-dimensional-dynamic-motion-analysis-of-the-first-carpometacarpal-ligaments
#9
Mitsuhiko Nanno, Norie Kodera, Yuji Tomori, Yusuke Hagiwara, Shinro Takai
PURPOSE: The purpose of this study was to analyze the dynamic motion of the first carpometacarpal (CMC) ligaments on a three-dimensional (3-D) surface model and to examine the changes in the ligament lengths during the motion of the first CMC joint. METHODS: Six fresh-frozen cadaver wrists were used to analyze the motion of the first CMC ligaments on a 3-D coordinate system using a digitizer. Four ligaments, namely, dorsoradial ligament (DRL), posterior oblique ligament (POL), superficial anterior oblique ligament (SAOL), and deep anterior oblique ligament (dAOL), were dissected and identified...
January 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28111498/establishment-of-local-diagnostic-reference-levels-for-quality-control-in-intraoral-radiography
#10
Maki Izawa, Yasuo Harata, Noriyoshi Shiba, Nobuhide Koizumi, Tomonori Ozawa, Nobutoshi Takahashi, Yasuhiko Okumura
OBJECTIVE: To investigate the dosage and imaging conditions for patients undergoing intraoral radiography at Meikai University Hospital and establish assurance and quality control data. METHODS: Tube voltage, exposure time, and air kinetic energy released per unit mass (air kerma) of three intraoral radiography units were measured. To calculate the patient entrance dose (PED) for each radiograph using Insight film, we extracted data for 1063 patients from their exposure records...
2017: Oral Radiology
https://www.readbyqxmd.com/read/28111396/a-method-for-the-automatic-exposure-control-in-pediatric-abdominal-ct-application-to-the-standard-deviation-value-and-tube-current-methods-by-using-patient-s-age-and-body-size
#11
Ken Furuya, Shinji Akiyama, Atushi Nambu, Yutaka Suzuki, Yuusuke Hasebe
We aimed to apply the pediatric abdominal CT protocol of Donnelly et al. in the United States to the pediatric abdominal CT-AEC. Examining CT images of 100 children, we found that the sectional area of the hepatic portal region (y) was strongly correlated with the body weight (x) as follows: y=7.14x + 84.39 (correlation coefficient=0.9574). We scanned an elliptical cone phantom that simulates the human body using a pediatric abdominal CT scanning method of Donnelly et al. in, and measured SD values. We further scanned the same phantom under the settings for adult CT-AEC scan and obtained the relationship between the sectional areas (y) and the SD values...
2017: Nihon Hoshasen Gijutsu Gakkai Zasshi
https://www.readbyqxmd.com/read/28046774/su-f-i-35-establishment-of-drl-and-dose-indicators-for-optimization-of-protectionin-pediatric-ct-in-saudi-arabia
#12
A Al-Haj, A Lobriguito
PURPOSE: To establish the national dose reference level for pediatric CT procedures in Saudi Arabia. It also aims to determine dose indicators that can be used for optimization of protection. METHODS: A retrospective study of patient demographic data, CT exposure parameters and dose indicators in DLP and CTDI volume for pediatric patients was undertaken. The CT procedures were chest, brain and abdomen. A total of 550 patients from 5 medical centers were included in the study...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/27913174/high-gain-driven-right-leg-circuit-for-dry-electrode-systems
#13
Federico N Guerrero, Enrique Spinelli
This paper presents an improved driven right leg (DRL) circuit compensation together with a practical implementation. The proposed design allows to increase common mode voltage attenuation compared with the widely used dominant pole compensation while maintaining the same proven stability margin and design criteria, and requiring only a modification of its passive feedback network. A sample implementation of the proposed DRL was obtained estimating the values of interference model parameters for a dry electrode measurement system...
January 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/27870830/clonal-fate-mapping-quantifies-the-number-of%C3%A2-haematopoietic-stem-cells-that-arise-during%C3%A2-development
#14
Jonathan Henninger, Buyung Santoso, Stefan Hans, Ellen Durand, Jessica Moore, Christian Mosimann, Michael Brand, David Traver, Leonard Zon
Haematopoietic stem cells (HSCs) arise in the developing aorta during embryogenesis. The number of HSC clones born has been estimated through transplantation, but experimental approaches to assess the absolute number of forming HSCs in a native setting have remained challenging. Here, we applied single-cell and clonal analysis of HSCs in zebrafish to quantify developing HSCs. Targeting creER(T2) in developing cd41:eGFP(+) HSCs enabled long-term assessment of their blood contribution. We also applied the Brainbow-based multicolour Zebrabow system with drl:creER(T2) that is active in early haematopoiesis to induce heritable colour barcoding unique to each HSC and its progeny...
January 2017: Nature Cell Biology
https://www.readbyqxmd.com/read/27833538/impaired-decision-making-and-loss-of-inhibitory-control-in-a-rat-model-of-huntington-disease
#15
Nicole El Massioui, Charlotte Lamirault, Sara Yagüe, Najia Adjeroud, Daniel Garces, Alexis Maillard, Lucille Tallot, Libo Yu-Taeger, Olaf Riess, Philippe Allain, Huu Phuc Nguyen, Stephan von Hörsten, Valérie Doyère
Cognitive deficits associated with Huntington disease (HD) are generally dominated by executive function disorders often associated with disinhibition and impulsivity/compulsivity. Few studies have directly examined symptoms and consequences of behavioral disinhibition in HD and its relation with decision-making. To assess the different forms of impulsivity in a transgenic model of HD (tgHD rats), two tasks assessing cognitive/choice impulsivity were used: risky decision-making with a rat gambling task (RGT) and intertemporal choices with a delay discounting task (DD)...
2016: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/27730457/results-from-a-phantom-based-multi-centre-paediatric-computed-tomography-dose-survey
#16
David L Thiele, Sarah-Ellyana Aliuddin, Mike Irvine, George P McGill
A computed tomography radiation dose survey was performed within our enterprise using three age-based paediatric phantoms representing a 1, 5 and 10 years old. Twenty-seven scanners were surveyed with volume computed tomography dose index and dose length product data collected for head, chest and abdomen-pelvis protocols at each age. Reconstruction method e.g. filtered back projection (FBP) or iterative (IR) was also recorded. About two-thirds of the 1 year old FBP chest scans exceeded the national Baby diagnostic reference level (DRL)...
December 2016: Australasian Physical & Engineering Sciences in Medicine
https://www.readbyqxmd.com/read/27729715/surgical-stabilization-for-symptomatic-carpometacarpal-hypermobility-a-randomized-comparison-of-a-dorsal-and-a-volar-technique-and-a-cohort-of-the-volar-technique
#17
Kim Robin Spekreijse, Guus Maarten Vermeulen, Thybout M Moojen, Harm P Slijper, Steven E R Hovius, Ruud W Selles, Reinier Feitz
BACKGROUND: Hypermobility of the first carpometacarpal joint is mostly surgically treated with a volar approached stabilization by Eaton, but recent studies indicate the importance of the dorsoradial and intermetacarpal ligaments (DRL and IML) for carpometacarpal joint stability. The aim of this study was to compare a dorsal and volar technique for primary carpometacarpal hypermobility regarding pain and functional outcome. METHODS: Patients with non-degenerative, painful carpometacarpal hypermobility were included and were randomly assigned to either the volar technique using the FCR, or a dorsal technique using the ECRL...
2016: European Journal of Plastic Surgery
https://www.readbyqxmd.com/read/27714925/diagnostic-reference-levels-for-digital-mammography-in-new-south-wales
#18
Moayyad E Suleiman, Mark F McEntee, Lucy Cartwright, Jennifer Diffey, Patrick C Brennan
INTRODUCTION: This work aims to explore radiation doses delivered in screening mammography in Australia, with a focus on whether compressed breast thickness should be used as a guide when determining patient derived diagnostic reference levels (DRLs). METHODS: Anonymized mammograms (52,405) were retrieved from a central database, and DICOM headers were extracted using third party software. Women with breast implants, breast thicknesses outside 20-110 mm and images with incomplete exposure or quality assurance (QA) data were excluded...
October 6, 2016: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/27672626/local-reference-patient-dose-evaluation-in-conventional-radiography-examinations-in-mazandaran-iran
#19
D Khoshdel-Navi, A Shabestani-Monfared, M R Deevband, R Abdi, M Nabahati
BACKGROUND: The most efficient application of ionizing radiation is serving medical purposes and using this radiation has caused people to learn that artificial sources of radiation exposure among these resources can be of highest exposure rate. OBIECTIVE: The present study is aimed at initially establishing a baseline for local-reference dose level in Mazandaran, Iran in 12 projections of the most conventional x-ray examination. METHODS: In this study, 13 public hospitals in Mazandaran province were selected for review and required data collected for ten adult patients with mean weight of 70±10kg in each projection...
June 2016: Journal of Biomedical Physics & Engineering
https://www.readbyqxmd.com/read/27646311/mice-and-rats-fail-to-integrate-exogenous-timing-noise-into-their-time-based-decisions
#20
Dilara Berkay, David Freestone, Fuat Balcı
Endogenous timing uncertainty results in variability in time-based judgments. In many timing tasks, animals need to incorporate their level of endogenous timing uncertainty into their decisions in order to maximize the reward rate. Although animals have been shown to adopt such optimal behavioral strategies in time-based decisions, whether they can optimize their behavior under exogenous noise is an open question. In this study, we tested mice and rats in a task that required them to space their responses for a minimum duration (DRL task) in different task conditions...
November 2016: Animal Cognition
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