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https://www.readbyqxmd.com/read/29456930/review-of-the-evidence-for-the-management-of-co-morbid-tic-disorders-in-children-and-adolescents-with-attention-deficit-hyperactivity-disorder
#1
REVIEW
Michael O Ogundele, Hani F Ayyash
Attention deficit hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder in children and adolescents, with prevalence ranging between 5% and 12% in the developed countries. Tic disorders (TD) are common co-morbidities in paediatric ADHD patients with or without pharmacotherapy treatment. There has been conflicting evidence of the role of psychostimulants in either precipitating or exacerbating TDs in ADHD patients. We carried out a literature review relating to the management of TDs in children and adolescents with ADHD through a comprehensive search of MEDLINE, EMBASE, CINAHL and Cochrane databases...
February 8, 2018: World Journal of Clinical Pediatrics
https://www.readbyqxmd.com/read/29456286/examining-thematic-similarity-difference-and-membership-in-three-online-mental-health-communities-from-reddit-a-text-mining-and-visualization-approach
#2
Albert Park, Mike Conway, Annie T Chen
Objectives: Social media, including online health communities, have become popular platforms for individuals to discuss health challenges and exchange social support with others. These platforms can provide support for individuals who are concerned about social stigma and discrimination associated with their illness. Although mental health conditions can share similar symptoms and even co-occur, the extent to which discussion topics in online mental health communities are similar, different, or overlapping is unknown...
January 2018: Computers in Human Behavior
https://www.readbyqxmd.com/read/29455443/narcissistic-implications-in-gambling-disorder-the-mediating-role-of-emotion-dysregulation
#3
Guyonne Rogier, Patrizia Velotti
Gambling Disorder (GD) is a complex psychopathology involving a numbers of cognitive, behavioral, emotional and neurobiological determinants. Previous research suggests that GD may frequently co-occur with Narcissistic Personality Disorder. However, there is still a lack of study investigating Pathological Narcissism (PN) in both its vulnerable and grandiose facets among clinical population. Moreover, emotional dysregulation is commonly thought to underlie GD albeit research on this topic remains poor. The present study aims to investigate the role of both vulnerable and grandiose narcissism in relation to GD as well as the mediator role played by emotion dysregulation in such link...
February 17, 2018: Journal of Gambling Studies
https://www.readbyqxmd.com/read/29455242/heightened-cxcr4-and-cxcl12-expression-in-nf1-associated-neurofibromas
#4
Beren Karaosmanoglu, Çetin Y Kocaefe, Figen Söylemezoğlu, Banu Anlar, Ali Varan, İbrahim Vargel, Sükriye Ayter
BACKGROUND: Neurofibromatosis type 1 (NF1) is a common autosomal dominantly inherited disorder that affects both the skin and the nervous system. NF1 occurs due to the mutations in the NF1 gene. Neurofibromas are the most common Schwann cell-based tumors in NF1 patients, which are mainly categorized into dermal and plexiform neurofibromas. Studies on different tumor types demonstrate that CXCR4 expression increases in tumor tissues and is linked to metastasis and cancer progression. PURPOSE: In the present study, we aimed to analyze the gene expression of CXCR4, and its ligand CXCL12, in human neurofibromas...
February 17, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29455060/major-depressive-disorder-and-depressive-symptoms-in-intermittent-explosive-disorder
#5
Gustavo C Medeiros, Liliana Seger, Jon E Grant, Hermano Tavares
It is estimated that between 1.7 and 2.6 million people have had intermittent explosive disorder (IED) during their life in the United States alone. Co-occurring psychiatric disorders are very common in IED, being major depressive disorder arguably the most common. The objective of this study was to examine the clinical correlates of IED and depressive manifestations in 74 treatment-seeking subjects. After controlling for confounders, there were associations between major depressive disorder and severity of depressive symptoms, and (a) higher assault scores, (b) more severe hostile behavior and (c) worse social adjustment...
February 9, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29450599/a-typology-of-satisfaction-with-mental-health-services-based-on-andersen-s-behavioral-model
#6
Marilyn Fortin, Zhirong Cao, Marie-Josée Fleury
OBJECTIVE: Patients with mental disorders (MDs) form a highly heterogeneous group, whose satisfaction with mental health services (MHS) may vary according to different variables. Identifying patient subgroups with similar levels of satisfaction may help identify variables that contribute to satisfaction or dissatisfaction with services. This study established a typology of patient satisfaction with MHS that revealed variables specific to each group. METHODS: The study included 325 patients with MDs across four health service networks offering integrated and diversified services...
February 15, 2018: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/29450253/drug-nicotine-and-alcohol-use-among-exercisers-does-substance-addiction-co-occur-with-exercise-addiction
#7
Attila Szabo, Mark D Griffiths, Rikke Aarhus Høglid, Zsolt Demetrovics
Background: Scholastic works suggest that those at risk for exercise addiction are also often addicted to illicit drugs, nicotine, and/or alcohol, but empirical evidence is lacking. Aims: The aim of the present work was to examine the co-occurrence of illicit drug, nicotine, and alcohol use frequency (prevalence of users) and severity (level of problem in users) among exercisers classified at three levels of risk for exercise addiction: (i) asymptomatic, (ii) symptomatic, and (iii) at-risk...
June 2018: Addictive Behaviors Reports
https://www.readbyqxmd.com/read/29450242/one-year-abstinence-improves-adhd-symptoms-among-patients-with-polysubstance-use-disorder
#8
Egon Hagen, Aleksander H Erga, Sverre M Nesvåg, James R McKay, Astri J Lundervold, Espen Walderhaug
Introduction: Attention-deficit/hyperactivity disorder (ADHD) is a common comorbid disorder in patients suffering from substance use disorder (SUD). Individuals with co-occurring SUD and ADHD are more likely than SUD patients without ADHD to have developed SUD at a younger age, be polysubstance users, and need inpatient treatment more often. The present study investigates whether individuals with polysubstance use disorder who remain abstinent for a year after entering treatment have a more substantial reduction in ADHD symptoms than those who relapsed and controls...
December 2017: Addictive Behaviors Reports
https://www.readbyqxmd.com/read/29447416/managing-opioid-use-disorder-and-co-occurring-posttraumatic-stress-disorder-among-veterans
#9
Rhonda Snow, Stephanie T Wynn
Support and safety measures are essential for Veterans admitted to acute psychiatric units with co-occurring posttraumatic stress disorder (PTSD) and opioid use disorder (OUD) to avoid unpleasant withdrawal symptoms. A human patient simulator was used to train clinicians to recognize opioid withdrawal symptoms. Clinicians were educated to assess for opioid withdrawal symptoms using the Clinical Opiate Withdrawal Scale. Knowledge was evaluated via pre/posttest. All participants' (N = 12) posttest scores improved...
February 15, 2018: Journal of Psychosocial Nursing and Mental Health Services
https://www.readbyqxmd.com/read/29445122/deep-phenotyping-of-speech-and-language-skills-in-individuals-with-16p11-2-deletion
#10
Cristina Mei, Evelina Fedorenko, David J Amor, Amber Boys, Caitlyn Hoeflin, Peter Carew, Trent Burgess, Simon E Fisher, Angela T Morgan
Recurrent deletions of a ~600-kb region of 16p11.2 have been associated with a highly penetrant form of childhood apraxia of speech (CAS). Yet prior findings have been based on a small, potentially biased sample using retrospectively collected data. We examine the prevalence of CAS in a larger cohort of individuals with 16p11.2 deletion using a prospectively designed assessment battery. The broader speech and language phenotype associated with carrying this deletion was also examined. 55 participants with 16p11...
February 14, 2018: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/29440390/high-dietary-fat-and-sucrose-results-in-an-extensive-and-time-dependent-deterioration-in-health-of-multiple-physiological-systems-in-mice
#11
James G Burchfield, Melkam A Kebede, Christopher C Meoli, Jacqueline Stöckli, P Tess Whitworth, Amanda L Wright, Nolan J Hoffman, Annabel Y Minard, Xiuquan Ma, James R Krycer, Marin E Nelson, Shi-Xiong Tan, Belinda Yau, Kristen C Thomas, Natalie K Y Wee, Ee-Cheng Khor, Ronaldo F Enriquez, Bryce Vissel, Trevor J Biden, Paul A Baldock, Kyle L Hoehn, James Cantley, Gregory J Cooney, David E James, Daniel J Fazakerley
Obesity is associated with metabolic dysfunction, including insulin resistance and hyperinsulinemia, and with disorders such as cardiovascular disease, osteoporosis, and neurodegeneration. Typically, these pathologies are examined in discrete model systems and with limited temporal resolution, and whether these disorders co-occur is therefore unclear. To address this question, we examined multiple physiological systems in male C57BL/6J mice following prolonged exposure to a high-fat/high-sucrose diet (HFHSD)...
February 13, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29439585/psychometric-properties-of-questionnaires-and-diagnostic-measures-for-autism-spectrum-disorders-in-adults-a-systematic-review
#12
Sarah Wigham, Jacqui Rodgers, Tom Berney, Ann Le Couteur, Barry Ingham, Jeremy R Parr
Accurately diagnosing autism spectrum disorders in adulthood can be challenging. Structured questionnaires and diagnostic measures are frequently used to assist case recognition and diagnosis. This study reviewed research evidence on structured questionnaires and diagnostic measures published since the National Institute for Health and Care Excellence evidence update. The Cochrane library, Medline, Embase and PsycINFO were searched. In all, 20 studies met inclusion criteria. Sensitivity and specificity of structured questionnaires were best for individuals with previously confirmed autism spectrum disorder diagnoses and reduced in participants referred for diagnostic assessments, with discrimination of autism spectrum disorder from mental health conditions especially limited...
February 1, 2018: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/29431904/atrial-fibrillation-and-venous-thromboembolism-evidence-of-bidirectionality-in-the-atherosclerosis-risk-in-communities-study
#13
P L Lutsey, F L Norby, A Alonso, M Cushman, L Y Chen, E D Michos, A R Folsom
BACKGROUND: Atrial fibrillation (AF) and venous thromboembolism (VTE) frequently co-occur. These conditions have shared risk factors and are accompanied by coagulation abnormalities. Furthermore, mechanistic pathways may directly link the disorders. OBJECTIVES: To test the hypothesis that individuals with incident AF are at greater risk of developing VTE, and those with VTE are at elevated risk of AF. We also tested whether associations were stronger in the first 6 months after the initial diagnosis, and explored race differences...
February 12, 2018: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/29431522/posttraumatic-stress-disorder-emotional-suppression-and-psychiatric-co-morbidity-in-patients-with-chronic-idiopathic-urticaria-a-moderated-mediation-analysis
#14
Man Cheung Chung, Christine Symons, Jane Gilliam, Edward R Kaminski
BACKGROUND: There is evidence suggesting that posttraumatic stress disorder (PTSD) symptom severity and CIU severity are linked and partially mediated by the high-anxious defense mechanism. What is unclear is whether emotional suppression, as a defense serving the opposite purpose for high-anxious defense, can also act as a mediator and whether this mediational effect is partly influenced by time since trauma and trauma type. AIMS: To investigate whether emotional suppression mediated the links between PTSD and CIU symptom severities, and PTSD and psychiatric co-morbid symptom severities...
February 12, 2018: Journal of Mental Health
https://www.readbyqxmd.com/read/29427538/the-impact-on-the-family-of-the-co-existing-conditions-of-children-with-autism-spectrum-disorder
#15
Alexandra M Petrou, Abigail Soul, Beena Koshy, Helen McConachie, Jeremy R Parr
We aimed to investigate whether the impact on families of children with Autism Spectrum Disorder (ASD) is associated with the number and/or type of emotional and behavioral co-existing conditions that parents/carers of children with ASD reported as occurring frequently. In addition, we examined whether there was a greater impact on families if their child was male, had lower levels of language, had more severe autism symptomatology, and whether impact was associated with the number and/or type of co-existing conditions...
February 10, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29423134/the-bidirectional-association-between-sleep-problems-and-autism-spectrum-disorder-a-population-based-cohort-study
#16
Maria E Verhoeff, Laura M E Blanken, Desana Kocevska, Viara R Mileva-Seitz, Vincent W V Jaddoe, Tonya White, Frank Verhulst, Maartje P C M Luijk, Henning Tiemeier
Background: Sleep difficulties are prevalent in children with autism spectrum disorder (ASD). The temporal nature of the association between sleep problems and ASD is unclear because longitudinal studies are lacking. Our aim is to clarify whether sleep problems precede and worsen autistic traits and ASD or occur as a consequence of the disorder. Methods: Repeated sleep measures were available at 1.5, 3, 6, and 9 years of age in 5151 children participating in the Generation R Study, a large prospective birth cohort in the Netherlands...
2018: Molecular Autism
https://www.readbyqxmd.com/read/29421368/construct-validation-of-the-hybrid-model-of-posttraumatic-stress-disorder-distinctiveness-of-the-new-symptom-clusters
#17
Madison W Silverstein, Nathalie Dieujuste, Lindsay B Kramer, Daniel J Lee, Frank W Weathers
Despite the factor analytic support for the seven-factor hybrid model (Armour et al., 2015) of posttraumatic stress disorder (PTSD), little research has examined the degree to which newly established symptom clusters (i.e., negative affect, anhedonia, dysphoric arousal, anxious arousal, externalizing behavior) functionally and meaningfully differ in their associations with other clinical phenomena. The aim of the current study was to examine the degree to which newly established PTSD symptom clusters differentially relate to co-occurring psychopathology and related clinical phenomena through Wald testing using latent variable modeling...
December 30, 2017: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/29420786/one-day-behavioral-intervention-for-distressed-veterans-with-migraine-results-of-a-multimethod-pilot-study
#18
C Huddleston, L Martin, K Woods, L Dindo
Introduction: Migraine, a chronic neurological disorder characterized by episodic severe headache pain and functional impairment, affects approximately 12% of the general US population. Veterans returning from Iraq or Afghanistan have two to four times the incidence of migraine of the general population. Veterans with migraines are more than twice as likely to have comorbid psychiatric conditions as veterans without migraines, with depression and post-traumatic stress disorder being most prevalent...
February 6, 2018: Military Medicine
https://www.readbyqxmd.com/read/29420639/cognitive-dysfunction-in-naturally-occurring-canine-idiopathic-epilepsy
#19
Rowena M A Packer, Paul D McGreevy, Hannah E Salvin, Michael J Valenzuela, Chloe M Chaplin, Holger A Volk
Globally, epilepsy is a common serious brain disorder. In addition to seizure activity, epilepsy is associated with cognitive impairments including static cognitive impairments present at onset, progressive seizure-induced impairments and co-morbid dementia. Epilepsy occurs naturally in domestic dogs but its impact on canine cognition has yet to be studied, despite canine cognitive dysfunction (CCD) recognised as a spontaneous model of dementia. Here we use data from a psychometrically validated tool, the canine cognitive dysfunction rating (CCDR) scale, to compare cognitive dysfunction in dogs diagnosed with idiopathic epilepsy (IE) with controls while accounting for age...
2018: PloS One
https://www.readbyqxmd.com/read/29417447/maternal-and-family-processes-in-different-subgroups-of-youth-with-autism-spectrum-disorder
#20
Jane Pei-Chen Chang, Meng-Chuan Lai, Miao-Chun Chou, Chi-Yung Shang, Yen-Nan Chiu, Wen-Che Tsai, Yu-Yu Wu, Susan Shur-Fen Gau
We compared the maternal reports on mothering and family processes between 160 youth with autism spectrum disorder (ASD) and 160 age and gender-matched typically developing (TD) youth stratified by personal characteristics from Taiwan. The ASD groups consisted of 51 'typical autism' (TA), 52 'high-functioning autism' (HFA), and 57 'Asperger syndrome (AS).' Maternal reports showed that youth with ASD obtained less affection and more protection from the mother, and had less active mother-child interactions and more behavioral problems at home...
February 8, 2018: Journal of Abnormal Child Psychology
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