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Indian herbal drugs

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https://www.readbyqxmd.com/read/27872562/development-of-quality-standards-of-medicinal-mistletoe-helicanthes-elastica-desr-danser-employing-pharmacopoeial-procedures
#1
K N Sunil Kumar, B Ravishankar, B Yashovarma, R Rajakrishnan, J Thomas
Helicanthes elastica (Desr.) Danser (Loranthaceae), commonly known as Indian mango mistletoe, is a parasitic shrub found widely growing on mango trees in southern India. Development of monographic quality standards is need of the hour for Pharmacopoeial/extra-Pharmacopoeial and folk medicinal plants. Systematic pharmacognostical evaluation of leaves of H. elastica has been carried out employing Pharmacopoeial procedures of testing herbal drugs. Macro-microscopic features of H. elastica leaf were recorded. Ethanolic extract was tested positive for alkaloids, steroids, carbohydrates, tannins, saponins and phenols...
November 2016: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/27761693/curcuma-longa-extract-reduces-inflammatory-and-oxidative-stress-biomarkers-in-osteoarthritis-of-knee-a-four-month-double-blind-randomized-placebo-controlled-trial
#2
Shobhit Srivastava, Anil K Saksena, Sanjay Khattri, Santosh Kumar, Raghubendra Singh Dagur
BACKGROUND AND PURPOSE: Curcuma longa L. (CL), an Indian herb, has been used to treat many disorders because of its wide spectrum of pharmacological activities. It has been shown to exhibit anti-oxidant and anti-inflammatory properties, and is being used as herbal remedy since ancient times. Osteoarthritis of knee (KOA) is a chronic painful disorder in which prolong use of non-steroidal anti-inflammatory drugs (NSAIDs) or steroids may result into many serious side effects; hence, there is a need to develop herbal drugs, having good analgesia without side effects...
October 19, 2016: Inflammopharmacology
https://www.readbyqxmd.com/read/27761067/genetic-and-chemical-profiling-of-gymnema-sylvestre-accessions-from-central-india-its-implication-for-quality-control-and-therapeutic-potential-of-plant
#3
Ashutosh Kumar Verma, Sunita Singh Dhawan, Seema Singh, Kumar Avinash Bharati, Jyotsana
BACKGROUND: Gymnema sylvestre, a vulnerable plant species, is mentioned in Indian Pharmacopeia as an antidiabetic drug. OBJECTIVE: Study of genetic and chemical diversity and its implications in accessions of G. sylvestre. MATERIALS AND METHODS: Fourteen accessions of G. sylvestre collected from Central India and assessment of their genetic and chemical diversity were carried out using ISSR (inter simple sequence repeat) and HPLC (high performance liquid chromatography) fingerprinting methods...
July 2016: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/27757269/anthelmintic-activity-of-a-standardized-extract-from-the-rhizomes-of-acorus-calamus-linn-acoraceae-against-experimentally-induced-cestodiasis-in-rats
#4
Purobi Nath, Arun K Yadav
BACKGROUND: The rhizomes of a herb Acorus calamus Linn. (Acoraceae) have been widely used as a traditional medicine to cure intestinal-helminthic infections in India and South Africa. AIM: This study was undertaken to investigate the in vivo anthelmintic activity of a standardized methanolic extract obtained from the rhizomes A. calamus in a rodent model. MATERIALS AND METHODS: A methanolic extract obtained from rhizomes of A. calamus was characterized for active principle using nuclear magnetic resonance (1)H NMR, (13)C NMR, mass and infrared spectroscopy...
September 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27707902/the-significance-of-ayurvedic-medicinal-plants
#5
Syal Kumar, Gustav J Dobos, Thomas Rampp
Traditional Indian medicine (ayurveda) is becoming increasingly popular, with many chronic conditions responding to it well. Most patients begin to take conventional medications as soon as their diagnoses are made, so ayurvedic treatments are usually undergone alongside and/or after conventional medical approaches. A detailed knowledge of the action of food, spices, and medicinal plants is needed in order to understand their potential influence fully. While societal use of ayurvedic plants and Indian spices is commonplace, without ill effect, the use of more concentrated products made from single plants, often in the form of teas or tablets, is of more concern...
October 5, 2016: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/27688026/estimating-herbal-product-authentication-and-adulteration-in-india-using-a-vouchered-dna-based-biological-reference-material-library
#6
Dhivya Shanmughanandhan, Subramanyam Ragupathy, Steven G Newmaster, Saravanan Mohanasundaram, Ramalingam Sathishkumar
INTRODUCTION: India is considered the 'medicinal garden' of the world, with 8000 medicinal plants of which 960 are commercial species that are traded nationally and globally. Although scientific studies estimate herbal product adulteration as 42-66 % in North America, India does not have any published marketplace studies and subsequent estimates of adulteration in an industry facing considerable supply demands. OBJECTIVES: The goal of this project is to provide an initial assessment of herbal product authentication and adulteration in the marketplace in India by (1) developing a biological reference material (BRM) herbal DNA library for Indian herbal species using DNA barcode regions (ITS2 and rbcL) in order to facilitate accurate species resolution when testing the herbal products; and (2) assessing herbal product identification using our BRM library; and (3) comparing the use of our BRM library to identify herbal products with that of GenBank...
September 29, 2016: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/27565948/simultaneous-determination-of-pyrroquinazoline-alkaloids-and-flavonoids-in-adhatoda-beddomei-and-adhatoda-vasica-and-their-marketed-herbal-formulations-using-ultra-high-performance-liquid-chromatography-coupled-with-triple-quadrupole-linear-ion-trap-mass-spectrometry
#7
Awantika Singh, Sunil Kumar, Vikas Bajpai, Brijesh Kumar
Adhatoda beddomei and Adhatoda vasica leaf, known as 'Vasaka' and/or 'Vasa' in Ayurveda and 'Malabar nut' in English, is an official drug in the Indian Pharmacopoeia. The medicinal properties of these plants are due to the presence of pyrroquinazoline alkaloids. An UHPLC-ESI/MS/MS method in both positive and negative electrospray ionization in multiple-reaction-monitoring mode was developed and validated for the estimation of alkaloids and flavonoids in Adhatoda species and their marketed herbal formulations...
August 26, 2016: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/27452657/contributions-of-indian-council-of-medical-research-icmr-on-medicinal-plants
#8
Neeraj Tandon, Satyapal Singh Yadav
ETHNOPHARMACOLOGICAL RELEVANCE: Medicinal plants belong to the oldest known health care products that have been used by human beings all over the world and are major components of the formulations used in indigenous system of medicine practiced in many countries. Besides, finding place as health supplements, nutraceuticals, cosmetics, herbal tea etc. there has been a global insurgence of interest, including India, leading to enormous research / activities in the area of medicinal plants...
July 21, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27394388/botanical-drugs-in-ayurveda-and-traditional-chinese-medicine
#9
Yogini Jaiswal, Zhitao Liang, Zhongzhen Zhao
ETHNOPHARMACOLOGICAL RELEVANCE: China and India have a long history in the therapeutic application of botanical drugs in traditional medicine. Traditional Chinese Medicine (TCM) and Ayurveda are considered as two of the most ancient systems of medicine, with history of more than two millennia. Medicinal plants are the principal medicinal materials used in both these systems. AIM OF THE REVIEW: This review discusses about the histories of Ayurveda and TCM, the common medicinal plants species, the drug processing strategies used, and the current statuses of these traditional systems of medicine (TSM)...
July 6, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27316579/neuropharmacological-properties-of-withania-somnifera-indian-ginseng-an-overview-on-experimental-evidence-with-emphasis-on-clinical-trials-and-patents
#10
Sarat C Yenesetti, M J Manjunath, Cftri Muralidhara
BACKGROUND Owing to the increasing aged population globally, disorders and diseases of the CNS are anticipated to increase and heavily impact the health care. As these neurodegenerative diseases (NDD) are complex, multifactorial and do not have identified etiological factors, unfortunately drugs developed for the purpose have not met with the expected success. Hence, there has been a constant demand for development of natural therapeutic adjuvants which are safe and possess the potential to attenuate multiple pathways...
June 14, 2016: Recent Patents on CNS Drug Discovery
https://www.readbyqxmd.com/read/27175337/internal-transcribed-spacer-guided-multiplex-pcr-for-species-identification-of-convolvulus-prostratus-and-evolvulus-alsinoides
#11
Sonal Sharma, Neeta Shrivastava
Shankhpushpi is a reputed drug from an Indian system of medicine for treating mental disorders and enhancing memory. Two herbs, namely Convolvulus prostratus Forssk. and Evolvulus alsinoides (L.) L., are commonly known as Shankhpushpi. Ambiguous vernacular identity can affect the scientific validity of the Shankpushpi-based herbal drug therapy. In the present investigation, a novel and sensitive multiplex PCR method based on polymorphism in the internal transcribed spacer (ITS) region was developed to establish the molecular identity of C...
May 2016: Acta Pharmaceutica Sinica. B
https://www.readbyqxmd.com/read/27041875/biological-and-phytopharmacological-descriptions-of-litchi-chinensis
#12
Eswar Kumar Kilari, Swathi Putta
Plants remain a vital source of drugs and at present, much emphasis is given to nutraceuticals. Herbal medicines have been the basis of treatment and cure for various diseases and physiological conditions in the traditional methods practiced such as ayurveda and homeopathy. Litchi chinensis belongs to the Sapindaceae family and is well-known in the Indian traditional system for its traditional uses. The parts of the plant used are leaves, flowers, fruits, seed, pulp, and pericarp. All parts of the plant are rich sources of phytochemicals--epicatechin; procyanidin A2 and procyanidin B2; leucocyanidin; cyanidin glycoside, malvidin glycoside, and saponins; butylated hydroxytoluene; isolariciresinol; kaempferol; rutin; and stigmasterol...
January 2016: Pharmacognosy Reviews
https://www.readbyqxmd.com/read/27011712/pharmacovigilance-study-of-ayurvedic-medicine-in-ayurvedic-teaching-hospital-a-prospective-survey-study
#13
Manjunath N Ajanal, Shradda U Nayak, Avinash P Kadam, B S Prasad
INTRODUCTION: Though Ayurveda is practiced in the Indian subcontinent since centuries, there is a paucity of systematic documentation related to the occurrence of adverse drug reactions (ADR) and other issues regarding the safety of Ayurveda medicines. AIM: To monitor and analyze the pattern and frequency of ADR to Ayurvedic medicines in an Ayurvedic hospital setup. MATERIALS AND METHODS: In this prospective study, ADR monitoring was done in KLE Ayurveda Secondary Care Hospital, Belgaum, Karnataka, India by spontaneous and intensive monitoring technique for a span of 1-year (June 2010 to May 2011)...
April 2015: Ayu
https://www.readbyqxmd.com/read/26973531/the-molecular-links-of-re-emerging-therapy-a-review-of-evidence-of-brahmi-bacopa-monniera
#14
REVIEW
Deepali Mathur, Kritika Goyal, Veena Koul, Akshay Anand
The convolution associated with memory is being resolved with advancement in neuroscience. According to the concurrent assumptions, synaptic plasticity forms one of the basis of memory formation, stabilization and strengthening. In Alzheimer's disease (AD), which is generally characterized by memory dysfunction, connections amongst the cells in the brain are attenuated or lost leading to degeneration of neural networks. Numerous attempts have been made to find new therapies for memory dysfunction with increasing attention and investments being laid on herbal drugs...
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/26929577/toxicological-evaluation-of-emblica-officinalis-fruit-extract-and-its-anti-inflammatory-and-free-radical-scavenging-properties
#15
Sushil Kumar Middha, Arvind Kumar Goyal, Prakash Lokesh, Varsha Yardi, Lavanya Mojamdar, Deepthi Sudhir Keni, Dinesh Babu, Talambedu Usha
BACKGROUND: Emblica officinalis (Euphorbiaceae), popularly known as Indian gooseberry or "Amla" in India, is used in Ayurveda as "rejuvenating herb" since ancient times. OBJECTIVE: This study was carried out to estimate toxicity, anti-inflammatory, and antioxidative activities of the methanolic extract of Emblica officinalis fruit (MEO) in an animal model. MATERIALS AND METHODS: Antioxidative property of MEO was assessed by in vitro assays such as phosphomolybdenum assay (total antioxidant capacity), free radical scavenging assays 1,1-diphenyl-2-picrylhydrazyl and 2,2'-azino-bis and 3-ethylbenzthiazoline-6-sulphonic acid (DPPH and ABTS method) and lipid peroxidation assay (LPO)...
October 2015: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/26851499/a-comprehensive-analysis-on-symplocos-racemosa-roxb-traditional-uses-botany-phytochemistry-and-pharmacological-activities
#16
REVIEW
Niyati Acharya, Sanjeev Acharya, Unnati Shah, Ripal Shah, Lal Hingorani
ETHNOPHARMACOLOGICAL RELEVANCE: Symplocos racemosa Roxb. belongs to a unigeneric family Symplocaceae, known as lodhra in Sanskrit; is a small evergreen tree, found throughout the tropical and sub-tropical countries. Ethnobotanical literature indicates use of S. racemosa in treatment of eye disease, skin diseases, ear diseases, liver and bowel complaints, tumors, uterine disorders, spongy and bleeding gums, asthma, fever, snake-bite, gonorrhea and arthritis. The main aim of this review is to provide detailed phytopharmacological profile on S...
April 2, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/26721197/effects-of-gymnema-sylvestre-extract-on-the-pharmacokinetics-and-pharmacodynamics-of-glimepiride-in-streptozotocin-induced-diabetic-rats
#17
Bhagyashree Kamble, Ankur Gupta, Ismail Moothedath, Laxman Khatal, Shirish Janrao, Amol Jadhav, B Duraiswamy
Gymnema sylvestre, important Indian traditional herbal medicine has been used for diabetes from several years and marketed as single or multi-herb formulations globally. People are consuming G. sylvestre along with conventional hypoglycemic drugs. Therefore, there is need of evidence based assessment of risk versus benefits when G. sylvestre co-administered with conventional oral hypoglycemic drugs. In present investigation, pharmacodynamics and pharmacokinetic interactions with oral hypoglycemic drug, glimepiride (GLM) was studied in streptozotocin (STZ) induced diabetic rats...
February 5, 2016: Chemico-biological Interactions
https://www.readbyqxmd.com/read/26709822/cissampelos-pareira-linn-natural-source-of-potent-antiviral-activity-against-all-four-dengue-virus-serotypes
#18
Ruchi Sood, Rajendra Raut, Poornima Tyagi, Pawan Kumar Pareek, Tarani Kanta Barman, Smita Singhal, Raj Kumar Shirumalla, Vijay Kanoje, Ramesh Subbarayan, Ravisankar Rajerethinam, Navin Sharma, Anil Kanaujia, Gyanesh Shukla, Y K Gupta, Chandra K Katiyar, Pradip K Bhatnagar, Dilip J Upadhyay, Sathyamangalam Swaminathan, Navin Khanna
BACKGROUND: Dengue, a mosquito-borne viral disease, poses a significant global public health risk. In tropical countries such as India where periodic dengue outbreaks can be correlated to the high prevalence of the mosquito vector, circulation of all four dengue viruses (DENVs) and the high population density, a drug for dengue is being increasingly recognized as an unmet public health need. METHODOLOGY/PRINCIPAL FINDINGS: Using the knowledge of traditional Indian medicine, Ayurveda, we developed a systematic bioassay-guided screening approach to explore the indigenous herbal bio-resource to identify plants with pan-DENV inhibitory activity...
December 2015: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/26681895/challenges-and-guidelines-for-clinical-trial-of-herbal-drugs
#19
REVIEW
Abida Parveen, Bushra Parveen, Rabea Parveen, Sayeed Ahmad
World Health Organization (WHO) has defined herbal medicines as finished labeled medicinal product that contain an active ingredient, aerial, or underground parts of the plant or other plant material or combinations. According to a report of WHO, about 80% of the world population is reported to rely on traditional medicine for their primary health care needs. Even in the developed countries, complementary or alternative medicine is gaining popularity. A report of a global survey on national policy on traditional medicine and regulation of herbal medicines indicated that about 50 countries including China, Japan, and Germany already have their national policy and laws on regulations of traditional medicines...
October 2015: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/26681882/standardization-and-in-vitro-antioxidant-activity-of-jatamansi-rhizome
#20
Mhaveer Singh, Mohammad A Khan, Masood S Khan, S H Ansari, Sayeed Ahmad
BACKGROUND: Nardostachys jatamansi Linn. commonly known as jatamansi is a well notorious drug in Indian systems of medicines having various health-related benefits and employed in various herbal formulations due to the presence of high levels of valuable phenolic constituents. The present study was aimed to quality assessment of Jatamansi rhizome by studying macro- and micro-scopic characters along with physicochemical tests, chemo-profiling using thin layer chromatography (TLC), and gas chromatography-mass spectrometry (GC-MS), in vitro antioxidant activity...
October 2015: Journal of Pharmacy & Bioallied Sciences
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