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Sexuality in neurological disease

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https://www.readbyqxmd.com/read/29297596/neuropathology-of-autonomic-dysfunction-in-synucleinopathies
#1
REVIEW
Elizabeth A Coon, Jeremy K Cutsforth-Gregory, Eduardo E Benarroch
The synucleinopathies-Parkinson's disease, dementia with Lewy bodies, multiple system atrophy, and pure autonomic failure-result from distinct patterns of abnormal α-synuclein aggregation throughout the nervous system. Autonomic dysfunction in these disorders results from variable involvement of the central and peripheral autonomic networks. The major pathologic hallmark of Parkinson's disease and dementia with Lewy bodies is Lewy bodies and Lewy neurites; of multiple system atrophy, oligodendroglial cytoplasmic inclusions; and of pure autonomic failure, peripheral neuronal cytoplasmic inclusions...
January 3, 2018: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/29273403/zika-virus-an-emerging-infectious-disease-with-serious-perinatal-and-neurologic-complications
#2
Thomas B Casale, Michael N Teng, Jamie P Morano, Thomas Unnasch, Charles J Lockwood
Zika virus (ZIKV) is a flavivirus that is primarily transmitted by Aedes aegypti, the mosquito vector also important in the transmission of the flaviviruses responsible for dengue fever, yellow fever and chikungunya. Due to occurrence in the same geographic regions, serological cross-reactivity, and similar, albeit often less severe clinical manifestations as dengue and chikungunya infections, ZIKV infection likely went undetected and/or misdiagnosed for many years. ZIKV is somewhat unique among flaviviruses in its ability to also be transmitted via sexual contact, non-sexual body fluids and perinatally...
December 19, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29237239/sex-steroid-hormones-and-brain-function-pet-imaging-as-a-tool-for-research
#3
REVIEW
R Moraga-Amaro, A van Waarde, J Doorduin, E F J de Vries
Sex steroid hormones are major regulators of sexual characteristic among species. These hormones, however, are also produced in the brain. Steroidal hormone-mediated signaling via the corresponding hormone receptors can influence brain function at a cellular level and thus affect behavior and higher brain functions. Altered steroid hormone signaling has been associated with psychiatric disorders, such as anxiety and depression. Neurosteroids are also thought to have a neuroprotective effect in neurodegenerative diseases So far, the role of steroid hormone receptors in physiological and pathological conditions have mainly been investigated post-mortem on animal or human brain tissues...
December 13, 2017: Journal of Neuroendocrinology
https://www.readbyqxmd.com/read/29235414/zikaplan-zika-preparedness-latin-american-network
#4
A Wilder-Smith, R Preet, K E Renhorn, R A Ximenes, L C Rodrigues, T Solomon, J Neyts, L Lambrechts, H Willison, R Peeling, A K Falconar, A R Precioso, J Logan, T Lang, H P Endtz, M C Erasmus, E Massad
The ongoing Zika virus (ZIKV) outbreak in Latin America, the Caribbean, and the Pacific Islands has underlined the need for a coordinated research network across the whole region that can respond rapidly to address the current knowledge gaps in Zika and enhance research preparedness beyond Zika. The European Union under its Horizon 2020 Research and Innovation Programme awarded three research consortia to respond to this need. Here we present the ZikaPLAN (Zika Preparedness Latin American Network) consortium...
2017: Global Health Action
https://www.readbyqxmd.com/read/29184787/correlation-of-self-reported-urologic-symptoms-with-systemic-health-conditions-in-minority-men
#5
Sarah Coleman Vij, Andrew Turk, Tianming Gao, Daniel A Shoskes
Background: To investigate the correlation between presence and severity of urologic symptoms and self-reported systemic health conditions in minority men. Methods: Questionnaires were distributed at a Men's Minority Health Fair. Urologic symptoms were assessed with the International Prostate Symptom Score (IPSS), Sexual Health Inventory for Men (SHIM) and NIH Chronic Prostatitis Symptom Score (CPSI). Each was graded as absent/mild [0], moderate [1] or severe [2] by standard criteria for each and totaled for a urologic score (US)...
October 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29160004/urological-dysfunction-in-young-women-an-inheritance-of-childhood
#6
Elisabetta Costantini, Ester Illiano, Konstantinos Giannitsas, Marco Prestipino, Antonio Luigi Pastore, Antonio Carbone, Giovanni Palleschi, Raffaele Balsamo, Franca Natale, Donata Villari, Vittorio Bini, Serena Maruccia, Maria-Teresa Filocamo, Alessandro Zucchi
OBJECTIVE: To investigate the correlation of a history of lower urinary tract symptomatology during childhood with lower urinary tract dysfunction in young adult women. SUBJECTS AND METHODS: This was a multicentre, prospective, case-control study conducted between April 2013 and November 2015. A total of 300 women, aged 18-40 years, participated. The case group comprised women attending urogynaecology clinics for various lower urinary tract complaints and the control group was recruited from a healthy population...
November 21, 2017: BJU International
https://www.readbyqxmd.com/read/29145185/hypersexuality-in-neurological-disorders-from-disinhibition-to-impulsivity
#7
M Béreau
Little is known about the neurological control of human sexual behavior. Investigating and measuring this behavior by using quantitative and objective methods is difficult. Insights from lesion studies contribute to analyze the effects of neurological disorders on human sexual behavior. In this chapter, we focus on frontal lobe lesions, brain injuries, epilepsia, dementia, and Parkinson disease to describe human sexual behavior disorders, in order to highlight cortical and subcortical brain regions and neural networks involved in human sexual behavior...
2018: Frontiers of Neurology and Neuroscience
https://www.readbyqxmd.com/read/29144824/17%C3%AE-hydroxylase-deficiency-is-an-underdiagnosed-disease-high-frequency-of-misdiagnoses-in-a-large-cohort-of-brazilian-patients
#8
Rafaela Fontenele, Marivânia Costa-Santos, Claudio E Kater
OBJECTIVE: 17α-Hydroxylase deficiency (P450c17D) is characterized by hypogonadism and mineralocorticoid hypertension. We aimed to estimate the relative incidence and spectrum of preliminary misdiagnoses in Brazilian P450c17D patients. DESIGN: Cross-sectional study. METHODS: We reviewed, updated, and analyzed data of 40 P450c17D patients (21 XY, 19 XX). RESULTS: Complete data were unavailable for two patients. Seven patients were relatives of an index case...
November 16, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/29119079/minimizing-nocebo-effect-pragmatic-approach
#9
REVIEW
Majed Chamsi-Pasha, Mohammed Ali Albar, Hassan Chamsi-Pasha
The nocebo effect, the inverse of the placebo effect, is a well-established phenomenon, yet under-appreciated. It refers to nonpharmacological, harmful, or undesirable effects occurring after active or inactive therapy. The frequency of adverse events can dramatically increase by informing patients about the possible side effects of the treatment, and by negative expectations on the part of the patient. Patients who were told that they might experience sexual side effects after treatment with β-blocker drugs reported these symptoms between three and four times more often than patients in a control group who were not informed about these symptoms...
October 2017: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/29110807/psychobiological-correlates-of-vaginismus-an-exploratory-analysis
#10
Elisa Maseroli, Irene Scavello, Sarah Cipriani, Manuela Palma, Massimiliano Fambrini, Giovanni Corona, Edoardo Mannucci, Mario Maggi, Linda Vignozzi
BACKGROUND: Evidence concerning the determinants of vaginismus (V), in particular medical conditions, is inconclusive. AIM: To investigate, in a cohort of subjects consulting for female sexual dysfunction, whether there is a difference in medical and psychosocial parameters between women with V and women with other sexual complaints. METHODS: A series of 255 women attending our clinic for female sexual dysfunction was consecutively recruited...
November 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29099327/extensive-cerebrovascular-disease-and-stroke-with-prolonged-prodromal-symptoms-as-first-presentation-of-perinatally-acquired-human-immunodeficiency-virus-infection-in-a-young-adult
#11
T G Chigonda, G T Chatora, G W Ngwende, R F Miller, R A Ferrand
A 26-year-old black African woman presented with an acute onset of hemiparesis and visual symptoms. This had been preceded several months by symptoms which were apparently psychiatric in nature. She had no apparent risk for cerebrovascular disease. Neurological evaluation revealed a striking burden of cerebrovascular disease for her age, including the rare stroke syndrome of basilar artery occlusion. Human immunodeficiency virus (HIV) infection was identified during clinical assessment. This was judged to be perinatally acquired, as there was no history of sexual debut or blood transfusion; her mother was taking antiretroviral therapy and she had facial planar warts and underlying bronchiectasis...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29079869/-new-aspects-of-symptomatic-ms-treatment-part%C3%A2-5-fatigue
#12
REVIEW
T Henze, W Feneberg, P Flachenecker, D Seidel, H Albrecht, M Starck, S G Meuth
The symptomatic treatment of multiple sclerosis (MS) is nowadays of similar importance as immunotherapy within a comprehensive treatment concept of this chronic disease. It makes a considerable contribution to the reduction of disabilities in activities of daily living as well as social and occupational life. Moreover, symptomatic treatment is of great importance for amelioration of the quality of life. Since our last survey of symptomatic MS treatment in 2004 and publication of the guidelines of the German Neurological Society and the Clinical Competence Network Multiple Sclerosis (Klinisches Kompetenznetz Multiple Sklerose, KKN-MS) in 2014 several developments within the topics of mobility, bladder and sexual function, vision, fatigue, cognition and rehabilitation have taken place...
October 27, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/29079868/-new-aspects-of-symptomatic-ms-treatment-part%C3%A2-6-cognitive-dysfunction-and-rehabilitation
#13
REVIEW
T Henze, W Feneberg, P Flachenecker, D Seidel, H Albrecht, M Starck, S G Meuth
The symptomatic treatment of multiple sclerosis (MS) is nowadays of similar importance as immunotherapy within a comprehensive treatment concept of this chronic disease. It makes a considerable contribution to the reduction of disabilities in activities of daily living as well as social and occupational life. Moreover, symptomatic treatment is of great importance for amelioration of the quality of life. Since our last survey of symptomatic MS treatment in 2004 and publication of the guidelines of the German Neurological Society and the Clinical Competence Network Multiple Sclerosis ("Klinisches Kompetenznetz Multiple Sklerose", KKN-MS) in 2014 several developments within the topics of mobility, bladder and sexual function, vision, fatigue, cognition and rehabilitation have taken place...
October 27, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/29079866/-new-aspects-of-symptomatic-ms-treatment-part%C3%A2-4-sexual-dysfunction-and-eye-movement-disorders
#14
REVIEW
T Henze, W Feneberg, P Flachenecker, D Seidel, H Albrecht, M Starck, S G Meuth
The symptomatic treatment of multiple sclerosis (MS) is nowadays of similar importance as immunotherapy within a comprehensive treatment concept of this chronic disease. It makes a considerable contribution to the reduction of disabilities in activities of daily living as well as social and occupational life. Moreover, symptomatic treatment is of great importance for amelioration of the quality of life. Since our last survey of symptomatic MS treatment in 2004 and publication of the guidelines of the German Neurological Society and the Clinical Competence Network Multiple Sclerosis (Klinisches Kompetenznetz Multiple Sklerose, KKNMS) in 2014, several developments within the topics of mobility, bladder and sexual function, vision, fatigue, cognition and rehabilitation have taken place...
October 27, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/29079865/-what-is-new-in-symptomatic-ms-treatment-part%C3%A2-3-bladder-dysfunction
#15
REVIEW
T Henze, W Feneberg, P Flachenecker, D Seidel, H Albrecht, M Starck, S G Meuth
The symptomatic treatment of multiple sclerosis (MS) nowadays is of similar importance as immunotherapy within a comprehensive concept of therapy of this chronic disease, since it contributes considerably to the reduction of disabilities in activities of daily living as well as social and occupational life. Moreover, symptomatic treatment is of great importance for amelioration of quality of life. Since our last survey of symptomatic MS treatment in 2004 and publication of the guidelines of the German Neurological Society and the Klinisches Kompetenznetz Multiple Sklerose (KKNMS) in 2014 several developments within the topics of mobility, bladder and sexual function, vision, fatigue, cognition and rehabilitation took place...
October 27, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/29063261/-what-is-new-in-symptomatic-ms-treatment-part%C3%A2-1-introduction-and-methodical-approach-ataxia-and-tremor
#16
REVIEW
T Henze, W Feneberg, P Flachenecker, D Seidel, H Albrecht, M Starck, S G Meuth
The symptomatic treatment of multiple sclerosis (MS) nowadays is of similar importance as immunotherapy within a comprehensive concept of therapy of this chronic disease, since it contributes considerably to the reduction of disabilities in activities of daily living as well as social and occupational life. Moreover, symptomatic treatment is of great importance for amelioration of quality of life. Since our last survey of symptomatic MS treatment in 2004 and publication of the guidelines of the German Neurological Society and the Klinisches Kompetenznetz Multiple Sklerose (KKN‑MS) in 2014 several developments within the topics of mobility, bladder and sexual function, vision, fatigue, cognition and rehabilitation took place...
October 23, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/29063259/-what-is-new-in-symptomatic-ms-treatment-part%C3%A2-2-gait-disorder-and-spasticity
#17
REVIEW
T Henze, W Feneberg, P Flachenecker, D Seidel, H Albrecht, M Starck, S G Meuth
The symptomatic treatment of multiple sclerosis (MS) nowadays is of similar importance as immunotherapy within a comprehensive concept of therapy of this chronic disease, since it contributes considerably to the reduction of disabilities in activities of daily living as well as social and occupational life. Moreover, symptomatic treatment is of great importance for amelioration of quality of life. Since our last survey of symptomatic MS treatment in 2004 and publication of the guidelines of the German Neurological Society and the Klinisches Kompetenznetz Multiple Sklerose (KKN‑MS) in 2014 several developments within the topics of mobility, bladder and sexual function, vision, fatigue, cognition and rehabilitation took place...
October 23, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/28975610/self-assessments-and-determinants-of-hrqol-in-a-german-ms-population
#18
S Nickel, O von dem Knesebeck, C Kofahl
OBJECTIVES: The importance of health-related quality of life (HRQoL) in multiple sclerosis (MS) is widely acknowledged. In 2015, a multicenter study was launched to assess the HRQoL and coping styles of chronically ill persons in Germany. The aims of this paper were (i) to describe how persons affected by MS assess their HRQoL and (ii) find out sociodemographic and disease-specific determinants of HRQoL. MATERIALS AND METHODS: A quantitative survey (optionally per paper-pencil or online) was conducted between March and October 2015 in Germany...
October 3, 2017: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/28967230/prevalence-of-overactive-bladder-in-china-taiwan-and-south-korea-results-from-a-cross-sectional-population-based-study
#19
Yao-Chi Chuang, Shih-Ping Liu, Kyu-Sung Lee, Limin Liao, Jianye Wang, Tag Keun Yoo, Romeo Chu, Budiwan Sumarsono
OBJECTIVE: The aim of the present study was to determine the prevalence of overactive bladder (OAB) in individuals aged ≥40 years in China, Taiwan, and South Korea. METHODS: The present cross-sectional population-representative Internet-based study investigated OAB symptoms in men and women aged ≥40 years using the overactive bladder symptom score. Additional instruments included the International Index of Erectile Function (men only) and the Sexual Quality of Life - Female (women only) questionnaires, as well as Patient Perception of Bladder Condition (PPBC)...
October 2, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28892594/male-infertility-the-other-side-of-the-equation
#20
Darren J Katz, Patrick Teloken, Ohad Shoshany
BACKGROUND: A male factor contributes to infertility in approximately 50% of couples who fail to conceive, causing significant psychosocial and marital stress. OBJECTIVE: This article reviews the general practitioner's (GP's) evaluation of male infertility and indications for referral to a male infertility specialist, and gives an overview of the specialist management of male infertility. DISCUSSION: Male infertility can result from anatomical or genetic abnormalities, systemic or neurological diseases, infections, trauma, iatrogenic injury, gonadotoxins and development of sperm antibodies...
September 2017: Australian Family Physician
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