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Septal perforation

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https://www.readbyqxmd.com/read/29765786/nasal-septal-perforation-in-propylthiouracil-induced-anti-neutrophil-cytoplasmic-antibody-associated-vasculitis
#1
Yusho Ishii, Tsuyoshi Shirai, Yousuke Hoshi, Yoko Fujita, Yuko Shirota, Hiroshi Fujii, Tomonori Ishii, Hideo Harigae
Here, we present the case of a 29-year-old woman with nasal septal perforation and positive myeloperoxidase- (MPO-) anti-neutrophil cytoplasmic antibody (ANCA). She had been diagnosed with Graves' disease and had been treated with propylthiouracil (PTU) for 14 months. A biopsy of the nasal septum revealed an infiltration of inflammatory cells, with no evidence of malignancy or granulomatous change. Because of the use of PTU, destructive nasal lesion, and positive MPO-ANCA, she was diagnosed with drug-induced ANCA-associated vasculitis (AAV) and was treated with prednisolone and methotrexate after the cessation of PTU...
2018: Case Reports in Rheumatology
https://www.readbyqxmd.com/read/29763940/simultaneous-septal-perforation-repair-with-septorhinoplasty-a-31-year-experience
#2
Russell W H Kridel, Sean William Delaney
Septal perforation repair and septorhinoplasty (SRP) each present unique surgical challenges. However, in many instances, these procedures may be performed together successfully. In this study, the authors aim to determine the safety and effectiveness of combining primary or revision SRP and septal perforation repair via an open approach. A retrospective review was carried out of all consecutive patients who had SRP and septal perforation repair via an open approach between 1986 and 2017 in the senior author's practice...
May 15, 2018: Facial Plastic Surgery: FPS
https://www.readbyqxmd.com/read/29753583/pyoderma-gangrenosum-on-the-nose
#3
Takuya Tomioka, Keiko Soma, Yoichiro Sato, Koshiro Miura, Ayako Endo
Pyoderma gangrenosum is a rare ulcerative condition associated with various systemic diseases. Lesions on the lower extremities and the trunk are common, but lesions on the nose are rare. Here we report a case of pyoderma gangrenosum on the nose. A 33-year-old woman presented with fever, nasal obstruction, and painful swelling on the nasal bridge. Physical examination revealed swellings on the nasal septal mucosa bilaterally. Computed tomography showed a septal abscess and a subcutaneous abscess on the nasal bridge...
May 9, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29731834/diagnosis-and-treatment-of-postoperative-intestinal-perforation-in-infants-and-young-children-with-congenital-heart-disease-a-report-of-three-cases
#4
Yong-Hong Zhang, Zhen-Liang Chen, Lei Shi, Zhong-Jian Chen, Xiang-Yang Dong, Bo Zhai
The aim of the present study was to analyze risk factors of intestinal perforation following surgery for the treatment of congenital heart disease in infants and young children, and to summarize experiences of diagnosis and treatment. A total of 3,270 children, who underwent congenital heart disease surgery under extracorporeal circulation from January 2010 to July 2015, were retrospectively analyzed. Among these children, three (0.09%) developed postoperative intestinal perforation. Primary diseases were Tetralogy of Fallot (two cases) and ventricular septal defect combined with atrial septal defect (one case)...
May 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29719981/surgical-perspective-of-percutaneous-device-closure-of-atrial-septal-defect
#5
Shyam Kumar Singh Thingnam, Sachin Mahajan, Vikas Kumar
Background Percutaneous device closure of an ostium secundum atrial septal defect is associated with excellent outcomes and cosmetic results but at the cost of occasional serious and sometimes fatal complications as well as lifelong follow-up. Surgical intervention is required in cases of device-related complications, which carries a slightly higher risk compared to primary closure of an atrial septal defect. We present a surgical perspective of device closure of atrial septal defect. Methods Our database was searched over 4 years for complications related to percutaneous device closure of atrial septal defect, which required surgical retrieval of the device and closure of the defect...
January 1, 2018: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/29714449/effect-of-mometasone-furoate-nasal-spray-on-the-dna-of-nasal-mucosal-cells
#6
Hakan Akkaş, Erdinç Aydın, Seda Türkoğlu Babakurban, Erkan Yurtcu, Özlem Yılmaz Özbek
Background/aim: Allergic rhinitis (AR) is a respiratory disease caused by inflammation of the nasal mucosa. Intranasal corticosteroids (ICs) are an effective treatment for AR; however, their use has been associated with atrophy in nasal mucosae. Because DNA damage has been linked to several chronic diseases, we hypothesize that use of ICs could cause DNA damage in nasal mucosa cells, leading to mucosal atrophy and septal perforation. Materials and methods: Sixty patients with moderate or severe AR were divided randomly into two groups...
April 30, 2018: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29658864/right-ventricular-perforation-by-a-defibrillator-lead-migrating-to-the-left-breast
#7
Jerneja Tasic, Rok Zbacnik, Igor Zupan, Jus Ksela
Cardiac perforation after an ICD implantation is a rare complication, with a reported incidence between 0.6-5.2%. Its manifestation might be acute, subacute, or delayed, with an acute perforation occurring within the first 24 hours after implantation, frequently accompanied by severe clinical signs, while subacute and delayed perforations have a more benign progression. Here, we report a case of a 69-year old patient with an acute right ventricular perforation by a defibrillator lead migrating all the way through the pericardium and thoracic wall into the left breast, with an unusually mild and benign clinical course, delaying prompt diagnosis and postponing subsequent surgical treatment...
March 5, 2018: Heart Surgery Forum
https://www.readbyqxmd.com/read/29649644/endoscopic-transseptal-approach-with-a-bilateral-nasoseptal-flap-in-challenging-skull-base-tumors
#8
Do Hyun Kim, Yong-Kil Hong, Sin-Soo Jeun, Jae-Sung Park, Soo Whan Kim, Jin Hee Cho, Yong Jin Park, Sung Won Kim
OBJECTIVE: To examine the utility of an endoscopic transseptal approach and the creation of a bilateral nasoseptal flap using a two-nostrils/four-hands technique in patients with challenging skull-base tumors. METHODS: The medical records of patients operated on via an endoscopic transseptal approach between 2009 and 2017 were retrospectively reviewed. Two patients with ossifying fibroma, two with orbital hemangioma, two with trigeminal nerve schwannoma, and one patient each with juvenile angiofibroma, meningioma, and myxofibrosarcoma were included in the study...
April 9, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29579028/acellular-human-dermal-allograft-as-a-graft-for-nasal-septal-perforation-reconstruction
#9
Dustin J Conrad, Han Zhang, David Wj Côté
OBJECTIVE: Nasal septal perforations pose a troubling source of morbidity for patients and a difficult problem for the Otolaryngologist. Multiple surgical techniques have been tried with inconsistent success. Prosthetic nasal buttons also have limitations, including patient intolerance and dissatisfaction. Acellular human dermal allograft, AlloDerm™ (LifeCell Branchburg, NJ) has been previously described as an alternative material for septal perforation repair. We aim to demonstrate objective and subjective outcomes, including quantification of patient's symptoms in septal perforation repair with AlloDerm...
March 20, 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29574724/extremely-thin-layer-plastification-for-focused-ion-beam-scanning-electron-microscopy-an-improved-method-to-study-cell-surfaces-and-organelles-of-cultured-cells
#10
E G VAN Donselaar, B Dorresteijn, D Popov-Čeleketić, W J VAN DE Wetering, T C Verrips, T Boekhout, C T W M Schneijdenberg, A T Xenaki, T P VAN DER Krift, W H Müller
Since the recent boost in the usage of electron microscopy in life-science research, there is a great need for new methods. Recently minimal resin embedding methods have been successfully introduced in the sample preparation for focused-ion beam scanning electron microscopy (FIB-SEM). In these methods several possibilities are given to remove as much resin as possible from the surface of cultured cells or multicellular organisms. Here we introduce an alternative way in the minimal resin embedding method to remove excess of resin from two widely different cell types by the use of Mascotte filter paper...
March 25, 2018: Journal of Microscopy
https://www.readbyqxmd.com/read/29573950/abdominal-gunshot-causing-ventricular-septal-injury-without-perforation-into-the-pericardium
#11
Martin I Sigurdsson, Benjamin Brockbank, John C Haney, Jon Andrews, David B MacLeod, Steven N Vaslef, Kelli R Brooks, Erin L Manning, Alina Nicoara
No abstract text is available yet for this article.
February 22, 2018: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29554411/the-utility-of-enlarging-symptomatic-nasal-septal-perforations
#12
Philip G Chen, Stephen Floreani, Peter-John Wormald
Nasal septal perforations cause a subset of patients to suffer with significant impairments in quality of life. While smaller perforations can often be surgically repaired, perforations exceeding 2 cm are challenging to close. These repairs are highly technical, and there is a lack of consensus regarding the most effective means to do so. The authors performed a retrospective chart review of patients with perforation enlargements and have found that, in select patients, enlarging the septal perforation's edge posterior to the head of the middle turbinates has proven effective in relieving symptoms...
March 2018: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/29554072/congenital-vomer-defect-incidentally-detected-on-preoperative-evaluation-for-nasal-septoplasty-and-turbinoplasty
#13
Junhui Jeong, Jun Cheol Park, Chang Eui Hong, Hyo Jin Chung, Jung Hyun Chang
A perforation in posterioinferior portion of nasal septum is rare and caused by vomeral defect. We report a case of 56-year-old man who had a vomer defect, which was detected incidentally during preoperative evaluation of nasal septoplasty and turbinoplasty. The patient had a surgery of septoplasty and bilateral turbinoplasty under general anesthesia. There was no septal mucosal tear or defect during septoplasty and turbinoplasty. When the patient who has vomeral defect with nasal obstruction is planned for septoplasty and turbinoplasty, the surgery should be performed carefully to protect the mucosa...
March 16, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29548523/effects-of-nasal-septum-perforation-repair-on-nasal-airflow-an-analysis-using-computational-fluid-dynamics-on-preoperative-and-postoperative-three-dimensional-models
#14
Tsutomu Nomura, Munetaka Ushio, Kenji Kondo, Shigeru Kikuchi
OBJECTIVE: The purpose of this research is to examine the changes in nasal airflow dynamics before and after the nasal perforation repair. METHODS: Three dimensional (3D) models of the nasal cavity before and after septal perforation repair was reconstructed using preoperative and postoperative computed tomography (CT) images of a patient. The numerical simulation was carried out using ANSYS CFX V15.0. Pre- and post-operative models were compared by their velocity, pressure (P), pressure gradient (PG), wall shear (WS), shear strain rate (SSR) and turbulence kinetic energy (TKE) in three plains...
March 13, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29512617/infective-endocarditis-of-a-bicuspid-aortic-valve-complicated-by-septal-aneurysm-and-mitral-aortic-intervalvular-fibrosa-pseudoaneurysm
#15
Hicaz Zencirkıran Ağuş, Oya Atamaner, Begüm Uygur, Ali Kemal Kalkan, Mehmet Ertürk
Aortic valve endocarditis can lead to the destruction or perforation of the leaflets, ring abscess, fistula, or perivalvular regurgitation; less commonly, the regurgitation itself may result in secondary damage to subaortic structures. Pseudoaneurysm of the mitral-aortic intervalvular fi brosa is a rare complication of native aortic valve endocarditis. This region is a relatively avascular area and is prone to endocarditis infection and subsequent aneurysm formation. Herein, the case of a 33-year-old man who was diagnosed with bicuspid aortic valve endocarditis complicated by a pseudoaneurysm, an aneurysm, and aortic valve rupture is described...
March 2018: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/29490769/safety-of-a-novel-intranasal-formulation-of-azelastine-hydrochloride-and-fluticasone-propionate-in-children-a-randomized-clinical-trial
#16
William Berger, Ellen Sher, Sandra Gawchik, Stanley Fineman
BACKGROUND: The safety of a novel intranasal formulation of azelastine hydrochloride (AZE) and fluticasone propionate (FP) has been established in adults and adolescents with allergic rhinitis but not in children <12 years old. OBJECTIVE: To evaluate the safety and tolerability of an intranasal formulation of AZE and FP in children ages 4-11 years with allergic rhinitis. METHODS: The study was a randomized, 3-month, parallel-group, open-label design...
March 1, 2018: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/29482688/complete-heart-block-due-to-occlusion-of-jailed-septal-perforator-after-percutaneous-coronay-intervention-of-proximal-left-anterior-descending-artery
#17
Ghazanfar Ali Shah, Jawaid Akbar Sial, Tahir Saghir
A 70-year diabetic and hypertensive lady admitted with acute coronary syndrome (ACS) underwent coronary angiography, which showed severe diffuse disease of proximal left anterior descending (LAD). She underwent percutaneous coronay intervention (PCI) of proximal LAD artery that resulted in occlusion of jailed first septal perforator. She remained stable and asymptomatic and was shifted to Coronary Care Unit (CCU) after successful procedure. Approximately five hours later, patient developed complete heart block (CHB) and became hemodynamically unstable...
March 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29482670/atrial-septal-defect-closure-with-the-new-cardia-ultrasept-ii%C3%A2-device-with-interposed-goretex-patch-mexican-experience-has-the-perforation-of-ivalon-s-membrane-been-solved
#18
Roberto Mijangos-Vázquez, Antonio J García-Montes, Elena M Soto-López, Verónica Guarner-Lans, Carlos Zabal
OBJECTIVES: The objective of this study was to demonstrate the safety and feasibility of using the new Cardia Ultrasept II™ device with interposed Goretex patch referring to the perforation of polyvinyl alcohol membrane. BACKGROUND: Great advances have been made in the development of devices for closure of atrial septal defect. The Cardia Ultrasept II™ with interposed Goretex patch is the modified last generation of Cardia devices, having the advantage of a super-low profile within the atria and an integral locking delivery-retrieval mechanism that ensures safe deployment...
May 2018: Cardiology in the Young
https://www.readbyqxmd.com/read/29476573/transient-left-septal-fascicular-block-in-the-setting-of-acute-coronary-syndrome-associated-with-giant-slurring-variant-j-wave
#19
Andrés Ricardo Pérez-Riera, Raimundo Barbosa-Barros, Wallam Lima Aragão, Rodrigo Daminello-Raimundo, Luiz Carlos de Abreu, Joseane Elza Tonussi Mendes Rossette do Valle, Isabel Cristina Esposito Sorpreso, Kjell Nikus
We report a case of acute coronary syndrome with transient prominent anterior QRS forces (PAF) caused by proximal subocclusion of the left anterior descending (LAD) coronary artery before the first septal perforator branch. The ECG change indicates left septal fascicular block (LSFB) with associated slurring-type giant J-wave. Currently, this J-wave variant is considered as a lambda-like wave or QRS-ST-T "triangulation". Its presence is indicative of poor prognosis because of the risk for cardiac arrest as a consequence of ventricular tachycardia/ventricular fibrillation (VT/VF)...
February 24, 2018: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/29472419/a-womb-like-a-broken-heart
#20
Amenda Ann Davis
Uterine perforation during hysteroscopic operative procedures is a potential complication well known to gynaecologists. Uterine septa are a commonly encountered Müllerian anomaly related to pregnancy loss and infertility. Hysteroscopic resection of septa has shown to improve pregnancy outcome. There are limited case reports of uterine rupture in subsequent pregnancies after hysteroscopic septal resection. Our patient had a hysteroscopic septal resection done a year prior which was complicated by a uterine fundal perforation, left to spontaneously heal after immediate sealing with cautery...
February 22, 2018: BMJ Case Reports
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