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Chronic otitis media

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https://www.readbyqxmd.com/read/29148198/ear-nose-and-throat-surgery-all-you-need-to-know-about-the-surgical-approach-to-the-management-of-middle-ear-effusions-in-australian-indigenous-and-non-indigenous-children
#1
REVIEW
Kelvin Kong, Francis J Lannigan, Peter S Morris, Amanda J Leach, Stephen J O'Leary
Otitis media (OM) is a common condition in Australia. It represents a spectrum of diseases from otitis media with effusion (OME) to chronic suppurative otitis media. For all the OM diagnoses, Australian Indigenous children have higher rates of early onset, severe and persistent disease. OME is the most common form of OM and often occurs after an upper respiratory tract infection. It can be difficult to diagnose (and often goes unrecognised). Hearing loss is the most important complication. The middle-ear effusion impedes the movement of the tympanic membrane and causes a conductive hearing loss of around 25 dB...
November 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29145277/tricho-hepato-enteric-syndrome-with-novel-skiv2l-gene-mutations-a-case-report
#2
Eitaro Hiejima, Takahiro Yasumi, Hiroshi Nakase, Minoru Matsuura, Yusuke Honzawa, Hirokazu Higuchi, Ikuo Okafuji, Tohru Yorifuji, Takayuki Tanaka, Kazushi Izawa, Tomoki Kawai, Ryuta Nishikomori, Toshio Heike
RATIONALE: Tricho-hepato-enteric syndrome (THES) is a rare disorder caused by mutations in the TTC37 or SKIV2L genes and characterized by chronic diarrhea, liver disease, hair abnormalities, and high mortality in early childhood due to severe infection or liver cirrhosis. PATIENT CONCERNS: The patient is the second child of three siblings born to non-consanguineous healthy Japanese parents. She had intrauterine growth retardation and was delivered at 33 weeks of gestation due to placental abruption...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29135867/analysis-of-otologic-features-of-patients-with-primary-ciliary-dyskinesia
#3
Kazuhiko Takeuchi, Masako Kitano, Hiroshi Sakaida, Satoko Usui, Sawako Masuda, Satoru Ogawa, Makoto Ikejiri, Mizuho Nagao, Takao Fujisawa, Kaname Nakatani
OBJECTIVE: To evaluate otologic features of primary ciliary dyskinesia (PCD), especially eardrum features, audiometric findings, and clinical course. STUDY DESIGN: Retrospective patient review. SETTING: Tertiary referral center. PATIENTS: Fifteen patients (mean age, 16.9 years [range, 1-32 yr]; 8 males and 7 females) diagnosed with PCD at our university hospital in the last 12 years. INTERVENTION: Diagnostic...
December 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29125825/understanding-the-aetiology-and-resolution-of-chronic-otitis-media-from-animal-and-human-studies
#4
REVIEW
Mahmood F Bhutta, Ruth B Thornton, Lea-Ann S Kirkham, Joseph E Kerschner, Michael T Cheeseman
Inflammation of the middle ear, known clinically as chronic otitis media, presents in different forms, such as chronic otitis media with effusion (COME; glue ear) and chronic suppurative otitis media (CSOM). These are highly prevalent diseases, especially in childhood, and lead to significant morbidity worldwide. However, much remains unclear about this disease, including its aetiology, initiation and perpetuation, and the relative roles of mucosal and leukocyte biology, pathogens, and Eustachian tube function...
November 1, 2017: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/29123985/covalent-bonding-of-heme-to-protein-prevents-heme-capture-by-nontypeable-haemophilus-influenzae
#5
Valerie Sgheiza, Bethany Novick, Sarah Stanton, Jeanetta Pierce, Breanne Kalmeta, Melody Frink Holmquist, Kyle Grimaldi, Kara L Bren, Lea Vacca Michel
Nontypeable Haemophilus influenzae (NTHi) are Gram-negative pathogens that contribute to a variety of diseases, including acute otitis media and chronic obstructive pulmonary disease. As NTHi have an absolute requirement for heme during aerobic growth, these bacteria have to scavenge heme from their human hosts. These heme sources can range from free heme to heme bound to proteins, such as hemoglobin. To test the impact of heme structural factors on heme acquisition by NTHi, we prepared a series of heme sources that systematically vary in heme exposure and covalent binding of heme to peptide/protein and tested the ability of NTHi to use these sources to support growth...
November 2017: FEBS Open Bio
https://www.readbyqxmd.com/read/29116047/factors-that-have-an-influence-on-bone-conduction-thresholds-changes-after-otosurgery-in-the-patients-operated-on-due-to-the-perforation-of-the-tympanic-membrane-with-the-preserved-ossicular-chain
#6
Maciej Wiatr, Agnieszka Wiatr, Sebastian Kocoń, Jacek Składzień
INTRODUCTION: The aim of the middle ear surgery is to eliminate abnormalities from the mucous, ensure the due airing of the postoperative cavity and reconstruct the sound-conducting system in the middle ear. Numerous reports can be found in literature on the changes to bone conduction as a consequence of middle ear surgery. STUDY OBJECTIVE: The aim of the work is to define the factors that affect bone conduction in the patients operated on due to the perforation of the tympanic membrane with the preserved and normal mobile ossicular chain...
August 31, 2017: Otolaryngologia Polska
https://www.readbyqxmd.com/read/29114285/pneumocephalus-presenting-as-sudden-thunderclap-headache
#7
Vivek S Guleria, Ajay Sharma, Chetan Sharda, Virendra Kumar
Pneumocephalus is a rare condition characterized by the presence of gas within the cranial cavity. This gas arises either from a trauma, tumor, surgical procedure, or occasionally from infection. Pneumocephalus secondary to chronic otitis media is an extremely rare phenomenon. We describe here a 70-year-old male, a known case of chronic suppurative otitis media who presented with sudden onset severe thunderclap headache and was eventually diagnosed as pneumocephalus.
October 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29106885/outpatient-management-of-pediatric-acute-mastoiditis
#8
Ahmed Alkhateeb, Francis Morin, Haya Aziz, Mayuri Manogaran, William Guertin, Melanie Duval
OBJECTIVE: Evaluate the Montreal Children's Hospital experience with outpatient management of uncomplicated acute mastoiditis with parenteral antibiotic therapy alone and determine if it is a safe alternative to inpatient management. SUBJECTS AND METHOD: A retrospective review of pediatric patients diagnosed with acute mastoiditis at a tertiary care pediatric hospital between 2013 and 2015 was performed. Patients with syndromes, immunodeficiency, cholesteatoma, chronic otitis media, cochlear implant in the affected ear, or incidental mastoid opacity were excluded...
November 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29106876/early-signs-and-symptoms-of-intracranial-complications-of-otitis-media-in-pediatric-and-adult-patients-a-different-presentation
#9
N A Van der Poel, E van Spronsen, D A Dietz de Loos, F A Ebbens
OBJECTIVES: The aim of this study was to review the clinical presentation and early signs and symptoms of otogenic intracranial complications (OIC) in children and adults. METHODS: retrospective chart review. The medical records of all children and adults admitted in our center with OIC during the period 2008-2017 were reviewed. Data concerning clinical presentation, treatment and outcomes were reviewed and analyzed. RESULTS: We included 47 patients with OIC: 21 children (range 1-13 years) and 26 adults (range 22-71 years)...
November 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29097032/-the-infections-of-the-ear
#10
Catherine Nowak, Lei Tanaka, Serge Bobin, Jérôme Nevoux
In front of external otitis in spite of a well-conducted treatment, especially in immunodeficient patient, it is always necessary to look for an osteomyelitis of the skull base that requires an urgent parenteral antibiotic treatment of several weeks. Acute otitis media (AOM) is the most common bacterial infection of the child. In children under 2 years with purulent AOM, antibiotic therapy with amoxicilline is systematic for a period of 8-10 days. After 2 years of age and with mild symptoms of AOM, symptomatic treatment may be justified as first-line treatment...
October 30, 2017: La Presse Médicale
https://www.readbyqxmd.com/read/29094065/a-cadaver-study-of-mastoidectomy-using-an-image-guided-human-robot-collaborative-control-system
#11
Myung Hoon Yoo, Hwan Seo Lee, Chan Joo Yang, Seung Hwan Lee, Hoon Lim, Seongpung Lee, Byung-Ju Yi, Jong Woo Chung
Objective: Surgical precision would be better achieved with the development of an anatomical monitoring and controlling robot system than by traditional surgery techniques alone. We evaluated the feasibility of robot-assisted mastoidectomy in terms of duration, precision, and safety. Study Design: Human cadaveric study. Materials and Methods: We developed a multi-degree-of-freedom robot system for a surgical drill with a balancing arm. The drill system is manipulated by the surgeon, the motion of the drill burr is monitored by the image-guided system, and the brake is controlled by the robotic system...
October 2017: Laryngoscope Investigative Otolaryngology
https://www.readbyqxmd.com/read/29072658/-the-evaluation-of-the-quality-of-life-in-the-patients-presenting-with-various-forms-of-chronic-otitis-media
#12
S Ya Kosyakov, Yu V Minavnina, A V Gunenkov
Chronic otitis media (COM) is a widespread pathological condition that affects up to 2% of the general population. Certain forms of this disease markedly deteriorate the quality of life of the patients which makes them overestimate the severity of harm to their health status and can be a cause of inflated expectations as regards the results of the planned surgical treatment. The linking element between the patient's expectations and the outcomes of the surgical intervention may be the recently developed questionnaires for the evaluation of the health-related quality of life (HRQoL)...
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/29072240/the-role-of-the-nasal-and-paranasal-sinus-pathologies-on-the-development-of-chronic-otitis-media-and-its-subtypes-a-computed-tomography-study
#13
M Damar, A E Dinç, D Erdem, S Bişkin, S Ş Eliçora, Y Ç Kumbul
OBJECTIVE: This objective of this study is to evaluate the presence and the coincidence of common nasal and paranasal sinus pathologies in adults suffering from chronic otitis media (COM) and its subtypes. MATERIALS AND METHODS: The study group comprised 354 ears of 177 patients who underwent tympanoplasty with or without mastoidectomy from January 2013 to February 2015 due to uni/bilateral COM. Chronic suppurative otitis media, intratympanic tympanosclerosis (ITTS), cholesteatoma, and tympanic membrane with retraction pockets constituted subtypes of COM...
September 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29071059/day-case-management-of-chronic-suppurative-otitis-media-with-cholesteatoma-with-canal-wall-down-technique-surgery-long-term-follow-up
#14
Giovanni Ralli, Giuseppe Nola, Alberto Taglioni, Michele Grasso, Massimo Ralli
No abstract text is available yet for this article.
July 18, 2017: Audiology Research
https://www.readbyqxmd.com/read/29065093/cochlear-implantation-in-cochlear-ossification-retrospective-review-of-etiologies-surgical-considerations-and-auditory-outcomes
#15
Ashish Vashishth, Andrea Fulcheri, Sampath Chandra Prasad, Margherita Bassi, Gianluca Rossi, Antonio Caruso, Mario Sanna
OBJECTIVES: 1) To review the surgical and auditory outcomes and complications of cochlear implantation in cases with cochlear ossification. 2) To evaluate association between the extent and etiology of ossification to outcomes. STUDY DESIGN: Retrospective study. SETTING: Otology and skull base surgery center. SUBJECTS AND METHODS: Charts of 40 patients (42 ears) with cochlear ossification undergoing cochlear implantation were reviewed...
October 23, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29065089/high-incidence-of-bell-s-palsy-after-mastoidectomy-a-longitudinal-follow-up-study
#16
Hyo Geun Choi, Songyong Sim, Sung Kwang Hong, Su-Kyoung Park, Hyo-Jeong Lee, Jiwon Chang
OBJECTIVE: The objective of this study was to compare the prevalence of Bell's palsy in participants who underwent mastoidectomy (to treat chronic otitis media) and nonmastoidectomy participants (control). METHODS: Using the national cohort study from the Korean Health Insurance Review and Assessment Service, mastoidectomy patients (2,045) and control participants (8,180) were matched 1:4 for age, sex, income, and region of residence. The prevalence of Bell's palsy in both the groups was measured from 0 to 10 years postoperation...
December 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29063965/prognostic-and-influencing-factors-of-tinnitus-in-chronic-otitis-media-after-tympanoplasty
#17
Ping Guo, Wenfang Sun, Wuqing Wang
The purpose of this study is to investigate what characteristics of tinnitus in patients with chronic otitis media was reduced after tympanoplasty and to assess the relationship between post-operative tinnitus reduction and pre-operative tinnitus tone, tinnitus duration, post-operative hearing recovery, and tympanogram. Medical records were prospective between March 2013 and May 2016. Audiologic evaluation by pure tone audiometry and acoustic impedance and tinnitus assessment using scores on the Tinnitus Handicap Inventory (THI) was conducted preoperatively and 6 months post-operatively...
October 24, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29058614/psychometric-characteristics-of-the-chronic-otitis-media-questionnaire-12-comq-12-stability-of-factor-structure-and-replicability-shown-by-the-serbian-version
#18
Bojana Bukurov, Nenad Arsovic, Sandra Sipetic Grujicic, Mark Haggard, Helen Spencer, Jelena Eric Marinkovic
BACKGROUND: Recently, demand for and supply of short-form patient-reported outcome measures (PROMs) have risen throughout the world healthcare. Our contribution to meeting that demand has been translating and culturally adapting the Chronic Otitis Media Questionnaire-12 (COMQ-12) for adults into Serbian and enhancing its psychometric base on the relatively large Serbian COM caseload. Chronic otitis media can seriously affect quality of life progressively and in long-term, and it remains the major source of hearing problems in the developing world...
October 23, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29056463/a-high-jugular-bulb-and-poor-development-of-perivestibular-aqueductal-air-cells-are-not-the-cause-of-endolymphatic-hydrops-in-patients-with-m%C3%A3-ni%C3%A3-re-s-disease
#19
Ryohei Oya, Takao Imai, Takashi Sato, Atsuhiko Uno, Yoshiyuki Watanabe, Suzuyo Okazaki, Yumi Ohta, Tadashi Kitahara, Arata Horii, Hidenori Inohara
OBJECTIVE: The presence of endolymphatic hydrops in the inner ear, which can be detected with gadolinium-enhanced magnetic resonance imaging (Gd-MRI), is widely recognized as the main pathological cause of Ménière's disease (MD). However, the precise mechanisms underlying the development of endolymphatic hydrops remains unclear. One hypothesis proposes a relationship between the presence of a high jugular bulb (HJB) and MD, which disrupts the vestibular aqueduct leading to the development of endolymphatic hydrops...
October 19, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29039253/stakeholder-driven-quality-improvement-a-compelling-force-for-clinical-practice-guidelines
#20
Richard M Rosenfeld, Peter C Wyer
Clinical practice guideline development should be driven by rigorous methodology, but what is less clear is where quality improvement enters the process: should it be a priority-guiding force, or should it enter only after recommendations are formulated? We argue for a stakeholder-driven approach to guideline development, with an overriding goal of quality improvement based on stakeholder perceptions of needs, uncertainties, and knowledge gaps. In contrast, the widely used topic-driven approach, which often makes recommendations based only on randomized controlled trials, is driven by epidemiologic purity and evidence rigor, with quality improvement a downstream consideration...
October 1, 2017: Otolaryngology—Head and Neck Surgery
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