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Chronic otitis media

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https://www.readbyqxmd.com/read/28088130/vaccine-candidates-against-nontypeable-haemophilus-influenzae-a-review
#1
REVIEW
Ava Behrouzi, Farzam Vaziri, Fatemeh Rahimi-Jamnani, Parviz Afrough, Mohammad Rahbar, Fereshteh Satarian, Seyed Davar Siadat
Nonencapsulated, nontypeable Hemophilus influenzae (NTHi) remains an important cause of acute otitis and respiratory diseases in children and adults. NTHi bacteria are one of the major causes of respiratory tract infections, including acute otitis media, cystic fibrosis, and community-acquired pneumonia among children, especially in developing countries. The bacteria can also cause chronic diseases such as chronic bronchitis and chronic obstructive pulmonary disease in the lower respiratory tract of adults...
2017: Iranian Biomedical Journal
https://www.readbyqxmd.com/read/28062125/propensity-of-pneumococcal-carriage-serotypes-to-infect-the-lower-airways-of-children-with-chronic-endobronchial-infections
#2
Kim M Hare, Heidi C Smith-Vaughan, Anne B Chang, Susan Pizzutto, Helen L Petsky, Gabrielle B McCallum, Amanda J Leach
BACKGROUND: Chronic endobronchial infections in children are responsible for a high disease burden. Streptococcus pneumoniae is frequently isolated; however, few publications have described serotypes associated with non-invasive lower airway infection. METHODS: Paired nasopharyngeal (NP) swabs and bronchoalveolar lavage (BAL) fluids were collected from children undergoing bronchoscopy for chronic cough. NP swabs were also collected from asymptomatic children in otitis media surveillance studies (controls)...
January 3, 2017: Vaccine
https://www.readbyqxmd.com/read/28056905/determinants-of-chronic-otitis-media-with-effusion-in-preschool-children-a-case-control-study
#3
Rebecca E Walker, Jim Bartley, David Flint, John M D Thompson, Edwin A Mitchell
BACKGROUND: Chronic otitis media with effusion (COME) is a prevalent upper airway infection resulting in hearing loss. The aim of this research was to determine risk factors for COME in preschool children. METHODS: A case-control design was conducted in Auckland, New Zealand from May 2011 until November 2013. The cases were children aged 3 and 4 years referred for tympanostomy tube placement due to a diagnosis of COME (n = 178). The controls were a random sample of healthy children aged 3 and 4 years from primary care practices (n = 209)...
January 6, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28027286/the-relationship-of-the-middle-ear-effusion-microbiome-to-secretory-mucin-production-in-pediatric-patients-with-chronic-otitis-media
#4
Anna Krueger, Stéphanie Val, Marcos Pérez-Losada, Karuna Panchapakesan, Joe Devaney, Vanessa Duah, Christine DeMasson, Marian Poley, Mary Rose, Diego Preciado
BACKGROUND: Acute otitis media (AOM), an infection of the middle ear, can become chronic (COM) following multiple episodes. Microbial influence on COM remains unclear. It's been reported that mucin glycoproteins are required for middle ear immune defense against pathogens. We aim to characterize the middle ear effusion (MEE) microbiome using high-throughput sequencing and assess potential associations in microbiome diversity with the presence of the secretory mucins MUC5B and MUC5AC. We hypothesize that MEEs containing MUC5B will exhibit a microbiome largely devoid of typical AOM bacteria...
December 23, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28024134/-acute-mastoiditis-with-retroauricular-abscess-a-report-of-two-cases
#5
Andrzej Misiak
Otogenic complications may occur as a result of both acute and chronic otitis media. The purpose of the diagnostic process and treatment of patients with otogenic complications is to identify and eliminate focal points of the infection. Due to general application of antibiotics, these complications are rarely observed. Retroauricular abscess may be the first symptom associated with the development of acute mastoiditis in patients with communication disturbances. Intravenous antibiotics and surgery have been successfully used for treatment in the two described cases...
December 22, 2016: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/27995276/seasonal-differences-of-tympanogram-and-middle-ear-findings-in-children
#6
S Knopke, A Böttcher, P Chadha, H Olze, F Bast
BACKGROUND: It is a known fact that bacterial or viral acute otitis media occurs more frequently in the winter months. Only a few older studies on seasonal differences in middle ear findings are available. These studies are based solely on tympanography, without correlation to intraoperative middle ear findings. This study addresses the question of whether seasonal differences can be found in the preoperative tympanogram and in the corresponding intraoperative findings in children with chronic middle ear problems...
December 19, 2016: HNO
https://www.readbyqxmd.com/read/27984431/assessment-of-the-factors-that-affect-the-anatomic-and-functional-success-of-cartilage-tympanoplasty-in-children
#7
Mahmut Sinan Yilmaz, Ahmet Kara, Mehmet Guven, Deniz Demir, Unal Erkorkmaz
OBJECTIVES: Many factors may influence the surgical outcome of tympanoplasty in children, including age, the size and location of perforation, otorrhea, status of contralateral ear, surgical technique, and adenoid hypertrophy. This study aims to evaluate the outcomes of pediatric cartilage tympanoplasty and to assess the factors that affect the success of tympanoplasty in children. METHODS: Children with chronic otitis media who underwent tympanoplasty using cartilage as graft material were evaluated retrospectively...
December 14, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27972912/antimicrobial-susceptibility-pattern-in-chronic-suppurative-otitis-media-patient-in-a-tertiary-care-hospital
#8
A Kumar, L Jayachandran, S Kumar, B R, S A
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27972905/sensitivity-analysis-of-antibiotic-cost-in-chronic-suppurative-otitis-media-patients-in-south-india-a-retrospective-observational-study
#9
S Kumar, L Jayachandran, A Kumar, S A, B R
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27956464/resistance-of-non-typeable-haemophilus-influenzae-biofilms-is-independent-of-biofilm-size
#10
Jennifer L Reimche, Daniel J Kirse, Amy S Whigham, W Edward Swords
The inflammatory middle ear disease known as otitis media can become chronic or recurrent in some cases due to failure of the antibiotic treatment to clear the bacterial etiological agent. Biofilms are known culprits of antibiotic-resistant infections; however, the mechanisms of resistance for non-typeable Haemophilus influenzae biofilms have not been completely elucidated. In this study, we utilized in vitro static biofilm assays to characterize clinical strain biofilms and addressed the hypothesis that biofilms with greater biomass and/or thickness would be more resistant to antimicrobial-mediated eradication than thinner and/or lower biomass biofilms...
February 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/27933630/comparison-of-cartilage-with-temporalis-fascia-tympanoplasty-a-meta-analysis-of-comparative-studies
#11
REVIEW
Mir Mohammad Jalali, Masoud Motasaddi, Ali Kouhi, Sasan Dabiri, Robabeh Soleimani
OBJECTIVE: To systematically review the results of type 1 tympanoplasty with temporalis fascia (TF) versus cartilage in patients with chronic otitis media (COM) for graft integration and hearing improvement. DATA SOURCES: The English language literature (until June 1, 2016) was searched, using Medline (via PubMed), Scopus, ProQuest, Ovid, Cochrane database, and Google Scholar. REVIEW METHODS: A comprehensive review of the literature was performed...
December 9, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27917157/otopathogenic-pseudomonas-aeruginosa-enters-and-survives-inside-macrophages
#12
Rahul Mittal, Christopher V Lisi, Hansi Kumari, M'hamed Grati, Patricia Blackwelder, Denise Yan, Chaitanya Jain, Kalai Mathee, Paulo H Weckwerth, Xue Z Liu
Otitis media (OM) is a broad term describing a group of infectious and inflammatory disorders of the middle ear. Despite antibiotic therapy, acute OM can progress to chronic suppurative otitis media (CSOM) characterized by ear drum perforation and purulent discharge. Pseudomonas aeruginosa is the most common pathogen associated with CSOM. Although, macrophages play an important role in innate immune responses but their role in the pathogenesis of P. aeruginosa-induced CSOM is not known. The objective of this study is to examine the interaction of P...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27916013/effectiveness-of-transperforation-myringoplasty-in-bilateral-chronic-otitis-media-patients-undergoing-contralateral-tympanoplasty
#13
A T Ihsan, K Ranjana
OBJECTIVES: Bilateral tympanic membrane perforation closure is usually performed by otosurgeons in two sittings. However, in this study, transperforation myringoplasty was performed alongside contralateral tympanoplasty in a single sitting. The effectiveness of transperforation myringoplasty procedure and the benefits of single sitting bilateral surgery were evaluated. METHODS: A prospective study of 50 selected patients with mucosal-type bilateral chronic otitis media was conducted...
January 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/27913087/a-case-of-multiple-empyema-caused-by-streptococcus-intermedius
#14
Akihito Kaga, Ryuzaburo Higo, Hiroshi Yoshikawa, Naoko Yokoi, Takuo Haruyama, Hiroaki Komatsu, Ayumi Yabe, Takeshi Kusunoki, Katsuhisa Ikeda
We report the case of a patient with multiple empyema present throughout his body, including chronic sinusitis and chronic suppurative otitis media, as well as subsequent epidural empyema, all caused by Streptococcus intermedius. A 38-year-old man presented with chief complaints of headache, left ear discharge, and nasal congestion. Imaging studies revealed pansinusitis, soft tissue signs in the mastoid cells, and otitis media. The patient was treated with meropenem hydrate, 6g/day. While clinical findings indicated improvement of the sinusitis, his headache did not improve...
November 29, 2016: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/27904919/-seasonal-differences-of-tympanogram-and-middle-ear-findings-in-children-german-version
#15
S Knopke, A Böttcher, P Chadha, H Olze, F Bast
BACKGROUND: It is a known fact that bacterial or viral acute otitis media occurs more frequently in the winter months. Only a few older studies on seasonal differences in middle ear findings are available. These studies are based solely on tympanography, without correlation to intraoperative middle ear findings. This study addresses the question of whether seasonal differences can be found in the preoperative tympanogram and in the corresponding intraoperative findings in children with chronic middle ear problems...
November 30, 2016: HNO
https://www.readbyqxmd.com/read/27895351/frequency-of-sensorineural-hearing-loss-in-chronic-suppurative-otitis-media
#16
Syed Sajjad Ali Zaidi, Hamdan Ahmed Pasha, Anwar Suhail, Talha Ahmed Qureshi
Chronic suppurative otitis media (CSOM) is defined as chronic otorrhea (i.e., lasting > 6-12 weeks) through a perforated tympanic membrane. It is generally associated with some degree of conductive hearing loss. However, recurrent ear infections due to perforated eardrum result in absorption of toxins and macromolecules into the cochlea leading to sensorineural hearing loss (SNHL). We planned to determine the frequency of sensorineural hearing loss in chronic suppurative otitis media. A descriptive cross-sectional study was conducted at Aga Kgan University Hospital, Karachi, from October 2013 to March 2014...
October 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27895000/severe-acute-otitis-media-and-acute-mastoiditis-in-adults
#17
Anu Laulajainen Hongisto, Jussi Jero, Antti Markkola, Riste Saat, Antti A Aarnisalo
OBJECTIVE: To evaluate and compare clinical and microbiological findings in adults hospitalized for acute otitis media (AOM) or mastoid infections (acute or latent). MATERIALS AND METHODS: We retrospectively reviewed the medical records of all adults (≥17 years old) hospitalized (between 2003 and 2012) at a tertiary referral center for acute mastoid infections or AOM not responding to outpatient medical treatment. RESULTS: Of the 160 patients in the study sample, 19% had an infection caused by S...
November 28, 2016: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/27879225/efficacy-of-posterior-canal-wall-reconstruction-using-autologous-auricular-cartilage-and-bone-p%C3%A3-t%C3%A3-in-chronic-otitis-media-with-cholesteatoma
#18
Min Kwan Baek, Sung Ho Choi, Dong Young Kim, Chang Hyun Cho, Yong Woo Kim, Kwang Ha Moon, Ju Hyoung Lee
OBJECTIVE: This study was designed to investigate the long-term results using the technique of canal wall up mastoidectomy and reconstruction of the posterior canal wall using bone pâté and auricular cartilage in the treatment of chronic otitis media with cholesteatoma. MATERIALS AND METHODS: A retrospective review was performed on 42 patients who underwent canal wall up mastoidectomy and posterior canal wall reconstruction at a single institution between November 2005 and November 2012...
November 23, 2016: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/27878589/chronological-changes-in-microbial-profiles-in-external-and-middle-ear-diseases-a-20-year-study-in-korea
#19
Hantai Kim, Oak-Sung Choo, Jeong Hun Jang, Hun Yi Park, Yun-Hoon Choung
Microbial infection is one of the most significant causes of ear diseases, but microbial profiles are very diverse according to the diseases and change over time. The purpose of the study was to clarify differences and chronological changes in causative pathogens among infectious ear diseases over the last 20 years, and to identify antibiotic resistance. In total, 1191 isolates were included from patients diagnosed with chronic otitis media without cholesteatoma (COM), cholesteatomatous otitis media (Chole), middle ear effusion (MEE), including acute otitis media and otitis media with effusion, and external otitis (EO)...
November 23, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27878362/a-3-d-analysis-of-the-protympanum-in-human-temporal-bones-with-chronic-ear-disease
#20
Henrique F Pauna, Rafael C Monsanto, Patricia Schachern, Michael M Paparella, Sebahattin Cureoglu
Eustachian tube dysfunction is believed to be an important factor to cholesteatoma development and recurrence of disease after surgical treatment. Although many studies have described prognostic factors, evaluation methods, or surgical techniques for Eustachian tube dysfunction, they relied on the soft tissues of its structure; little is known about its bony structure-the protympanum-which connects the Eustachian tube to the tympanic cavity, and can also be affected by several inflammatory conditions, both from the middle ear or from the nasopharynx...
November 22, 2016: European Archives of Oto-rhino-laryngology
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