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Endophthalmitis

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https://www.readbyqxmd.com/read/28937147/comparison-of-effectiveness-and-safety-between-conbercept-and-ranibizumab-for-treatment-of-neovascular-age-related-macular-degeneration-a-retrospective-case-controlled-non-inferiority-multiple-center-study
#1
J Cui, D Sun, H Lu, R Dai, L Xing, H Dong, L Wang, D Wei, B Jiang, Y Jiao, M M Jablonski, S Charles, W Gu, H Chen
PurposeTo compare the efficacy and safety of conbercept and ranibizumab when administered according to a treat-and-extend (TREX) protocol for the treatment of neovascular age-related macular degeneration (AMD) in China.Patients and methodsBetween May 2014 and May 2015, 180 patients were treated in a 1 : 1 ratio using conbercept or ranibizumab from four hospitals. Patients received either conbercept 0.5 mg or ranibizumab 0.5 mg intravitreal injections. Follow-up time was 1 year and treated based on a TREX approach...
September 22, 2017: Eye
https://www.readbyqxmd.com/read/28936060/endophthalmitis-due-to-proteus-vulgaris-after-pars-plana-vitrectomy-with-devastating-outcome
#2
Abdullah S Al-Kharashi, Abdulmajeed S Al-Kharshi, Yasser H Al-Faky
Postoperative infectious endophthalmitis is rare, yet devastating loss of vision or loss of the eye can occur due to a highly purulent microorganism or uncontrolled endophthalmitis that may spread to all coats of the eye. We report, herewith, a case of rapidly progressive postoperative endophthalmitis after pars plana vitrectomy which ended up with enucleation. The isolated microorganism was Proteus vulgaris which has not been reported as causative bacteria of postoperative infections following pars plana vitrectomy...
April 2017: Middle East African Journal of Ophthalmology
https://www.readbyqxmd.com/read/28936051/bacterial-contamination-of-multi-dose-eye-drops-at-ophthalmology-department-university-of-gondar-northwest-ethiopia
#3
Asegedech Tsegaw, Asamere Tsegaw, Tefera Abula, Yared Assefa
PURPOSE: Ophthalmic solutions used for both diagnostic and therapeutic purposes were found to be contaminated with bacteria pathogens and caused serious ocular infections such as keratitis and endophthalmitis. The objective was to assess the magnitude and pattern of bacterial contamination of multi-dose ophthalmic medications and investigate the drug susceptibility pattern of the isolates in the Department of Ophthalmology at Gondar University Teaching Hospital. METHODS: A total of 100 ophthalmic medications in-use by patients and eye-care workers have been taken and cultured for potential bacterial contamination in the Microbiology Department after 1 week and >1 week of use...
April 2017: Middle East African Journal of Ophthalmology
https://www.readbyqxmd.com/read/28932504/effects-of-intracameral-cefuroxime-on-corneal-endothelial-cell-counts-and-its-morphology-after-cataract-surgery
#4
Kourosh Shahraki, Mohammad Naeim Amini Fard, Farkhondeh Shahri, Rama Pourmatin, Tafgeh Mohammadi, Paria Ghasemi Boroumand, Kianoush Shahraki
BACKGROUND: Endophthalmitis is one of the most important complications after cataract surgery and in case event can cause many symptoms, such as severe decrease in eyesight and/or even the loss of vision. Employing methods to reduce this problem is very important. The aim of this study was to evaluate the effect of intracameral cefuroxime after cataract surgery on corneal endothelial cell counts and its morphology. METHODS: In this study, 32 eyes of 30 patients underwent endothelial cell count and morphology assessment by ConfoScan III device before and 1 month after cataract surgery...
June 2017: Interventional Medicine & Applied Science
https://www.readbyqxmd.com/read/28931202/different-sized-incisions-for-phacoemulsification-in-age-related-cataract
#5
REVIEW
Chongfei Jin, Xinyi Chen, Andrew Law, Yunhee Kang, Xue Wang, Wen Xu, Ke Yao
BACKGROUND: Age-related cataract is the principal cause of blindness and visual impairment in the world. Phacoemulsification is the main surgical procedure used to treat cataract. The comparative effectiveness and safety of different-sized incisions for phacoemulsification has not been determined. OBJECTIVES: The aim of this systematic review was to assess the effectiveness and safety of smaller versus larger incisions for phacoemulsification in age-related cataract...
September 20, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28925927/postoperative-endophthalmitis-caused-by-bosea-thiooxidans
#6
Vaidehi S Dedania, Devon H Ghodasra, David N Zacks
PURPOSE: To report an unusual case of postcataract endophthalmitis secondary to Bosea thiooxidans. METHODS: Case report. RESULTS: An 86-year-old man presented with postoperative endophthalmitis 3 weeks after uncomplicated cataract surgery. He complained of a headache and blurry vision but denied having eye pain. Slit-lamp examination demonstrated leukocytes with a fibrinous membrane in the anterior segment and vitritis. A diagnosis of acute postoperative endophthalmitis was made, and the patient was treated with intravitreal antibiotics...
October 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28925926/resolution-of-treatment-resistant-subretinal-fluid-in-a-patient-with-exudative-age-related-macular-degeneration-following-endophthalmitis
#7
Peter M Kally, Yossi Sidikaro, Colin A McCannel
PURPOSE: This is the first report to the best of the authors' knowledge to show resolution of subretinal fluid and treatment requirement in a case of exudative age-related macular degeneration (eAMD) with persistent fluid despite treatment that resolved following an episode of culture-positive bacterial endophthalmitis. METHODS: A 73-year-old man with history of eAMD of the right eye presented with acute postinjection bacterial endophthalmitis 3 days after injection...
October 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28925741/endophthalmitis-following-strabismus-surgery-iposc-global-study
#8
Ofira Zloto, Eedy Mezer, Luis Ospina, Branislav Stankovic, Tamara Wygnanski-Jaffe
PURPOSE: To examine the characteristics of patients with endophthalmitis after strabismus surgery (PSSE), the characteristics of the strabismus surgery, treatment, and prognosis as reported by pediatric ophthalmologists who are members of the American Association for Pediatric Ophthalmology and Strabismus (AAOPS) around the world. METHODS: An email communication was sent to all members of AAPOS. The email included a web link to a survey that included 34 questions that examined the characteristics of patients with endophthalmitis after strabismus surgery...
September 19, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28922308/large-retinal-pigment-epithelial-rip-associated-with-bullous-retinal-and-choroidal-detachment
#9
Jesse T McCann, Michael Engelbert
PURPOSE: To report a giant retinal pigment epithelium rip in a patient with a bullous retinal and choroidal detachment. METHODS: Case report with widefield imaging, fundus autofluorescence, and optical coherence tomography of the retina. RESULTS: This 62-year-old patient had a history of advanced glaucoma, trabeculectomy, blebitis, and endophthalmitis. He had cataract surgery 6 weeks before presentation. He was found to have a large bullous retinal and choroidal detachment with a large retinal pigment epithelium tear at the limit of the choroidal detachment...
October 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28918060/outcomes-of-ahmed-glaucoma-valve-revision-in-pediatric-glaucoma
#10
Ahmed Mansour Al-Omairi, Aliah H Al Ameri, Sami Al-Shahwan, Arif O Khan, Ibrahim Al-Jadaan, Ahmed Mousa, Deepak P Edward
PURPOSE: Encapsulation of the Ahmed glaucoma valve (AGV) plate is a common cause for postoperative elevation of intraocular pressure, especially in children. Many reports have described the outcomes of AGV revision in adults. However, the outcomes of AGV revision in children are poorly documented. The aim of this study was to determine the outcomes of AGV revision in children. DESIGN: Retrospective cross sectional study METHODS: A retrospective chart review of patients less than 15 years of age who underwent AGV revision with a minimum postoperative follow-up of six months was conducted...
September 13, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28900682/treatment-of-staphylococcus-aureus-infections
#11
Michael Z David, Robert S Daum
Staphylococcus aureus, although generally identified as a commensal, is also a common cause of human bacterial infections, including of the skin and other soft tissues, bones, bloodstream, and respiratory tract. The history of S. aureus treatment is marked by the development of resistance to each new class of antistaphylococcal antimicrobial drugs, including the penicillins, sulfonamides, tetracyclines, glycopeptides, and others, complicating therapy. S. aureus isolates identified in the 1960s were sometimes resistant to methicillin, a ß-lactam antimicrobial active initially against a majority S...
September 13, 2017: Current Topics in Microbiology and Immunology
https://www.readbyqxmd.com/read/28895709/recombinant-tissue-plasminogen-activator-treatment-for-intracardiac-vegetation-in-a-very-low-birth-weight-infant
#12
Abdurrahman A Ozdemir
Developing treatment options have resulted in prolonged admission and increased bacterial and fungal nosocomial infections as well as improved survival in neonatal intensive care unit. Invasive fungal infections in newborns are associated with significant morbidity and mortality and can cause endorgan dissemination such as endocarditis, endophthalmitis, septic arthritis, obstructive nephropathy and meningitis. Endocarditis requires aggressive systemic antifungal therapy and sometimes surgical intervention in neonates...
October 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28893456/-rare-causes-of-childhood-leukocoria
#13
J-P Diagne, A S Sow, A M Ka, A M Wane, P A Ndoye Roth, E A Ba, M E De Medeiros, J M Ndiaye, H M Diallo, H Kane, S Sow, M Nguer, E M Sy, P A Ndiaye
PURPOSE: The purpose was to record the causes of leukocoria among children under 10years of age and to determine the proportion of rare causes of leukocoria. PATIENTS AND METHODS: This retrospective study was conducted over a period of ten years, from January 1, 2004 to December 31, 2013, in patients under 10years of age who were referred for leukocoria. RESULTS: Leukocoria represented one of the ten reasons for consultation among children under 10years of age...
September 8, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28884024/combined-phacoemulsification-and-intravitreal-dexamethasone-implant-ozurdex%C3%A2-in-diabetic-patients-with-coexisting-cataract-and-diabetic-macular-edema
#14
Claudio Furino, Francesco Boscia, Alfredo Niro, Ermete Giancipoli, Maria Oliva Grassi, Giuseppe D'amico Ricci, Francesco Blasetti, Michele Reibaldi, Giovanni Alessio
PURPOSE: To investigate the effectiveness and safety of combined phacoemulsification and dexamethasone intravitreal implant in patients with cataract and diabetic macular edema. METHODS: In this two-center, retrospective, single-group study, the charts of 16 consecutive patients who underwent combined phacoemulsification and intravitreal dexamethasone implant were retrospectively reviewed. These 16 patients, 7 men and 9 women, were observed at least 3 months of follow-up...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28884023/clinical-features-and-visual-acuity-outcomes-in-culture-positive-endogenous-fungal-endophthalmitis-in-southern-china
#15
Fang Duan, Yao Yang, Zhaohui Yuan, Yongxin Zheng, Zhixing Cheng, Xiaofeng Lin
PURPOSE: To report the causative organisms, management strategies, and visual outcomes of culture-proven endogenous fungal endophthalmitis in a case series from southern China. METHODS: We reviewed the microbiological and medical records of patients with culture-positive endogenous fungal endophthalmitis visiting the Zhongshan Ophthalmic Center, Guangzhou, China, between January 1, 2006, and March 31, 2016. RESULTS: The inclusion criteria were met in 32 eyes of 29 patients...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28872724/successful-treatment-of-bilateral-endogenous-fusarium-solani-endophthalmitis-in-a-patient-with-acute-lymphocytic-leukemia
#16
Ilaria Rizzello, Fausto Castagnetti, Pier Giorgio Toschi, Patrizia Bertaccini, Laura Primavera, Michela Paolucci, Luca Faccioli, Luca Spinardi, Russell E Lewis, Michele Cavo, Marta Stanzani
Fusarium spp. are an uncommon cause of fungemia in immunocompromised and neutropenic patients that may hematogenously disseminate to the eyes. Herein, we describe a patient with acute lymphoblastic leukemia and a prior history of extensive corticosteroid exposure who developed disseminated Fusarium solani infection following chemotherapy despite posaconazole prophylaxis. She was successfully treated with combination liposomal amphotericin B and voriconazole, intraocular injections of voriconazole, topical amphotericin B and bilateral vitrectomy...
September 5, 2017: Mycoses
https://www.readbyqxmd.com/read/28872517/favorable-outcome-in-coccidioides-endophthalmitis-a-combined-medical-and-surgical-treatment-approach
#17
Jennifer J Ling, Derek J Bays, George R Thompson, Ala Moshiri, Mark J Mannis
PURPOSE: To describe a case of Coccidioides endophthalmitis that resulted in a favorable visual outcome after a combined medical and surgical approach. METHODS: A 33-year-old previously healthy woman was referred for evaluation of dyspnea and left-sided vision loss, which began 3 months before, after a trip to Nevada. She was found to have a pulmonary cavitary lesion and fluffy white material in the anterior chamber. An aqueous and vitreous paracentesis grew Coccidioides species...
August 31, 2017: Cornea
https://www.readbyqxmd.com/read/28865239/-principles-of-pharmacology-in-the-eye
#18
REVIEW
Sahar Awwad, Abeer H A Mohamed Ahmed, Garima Sharma, Jacob S Heng, Peng T Khaw, Steve Brocchini, Alastair Lockwood
The eye is a highly specialised organ that is subject to a huge range of pathology. Both local and systemic disease may affect different anatomical regions of the eye. The least invasive routes for ocular drug administration are topical (e.g. eyedrops) and systemic (e.g. tablets) formulations. Barriers that subserve as protection against pathogen entry also restrict drug permeation. Topically administered drugs often display limited bioavailability due to many physical and biochemical barriers including the pre-corneal tear film, the structure and biophysiologic properties of the cornea, the limited volume that can be accommodated by the cul-de-sac, the lacrimal drainage system and reflex tearing...
September 2, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28861733/patterns-of-uveitis-in-children-at-the-apex-institute-for-eye-care-in-india-analysis-and-review-of-literature
#19
Brijesh Takkar, Pradeep Venkatesh, Nripen Gaur, Sat Pal Garg, Rajpal Vohra, Supriyo Ghose
AIM: To study patterns of uveitis in Indian children and compare with data sets published earlier in the literature. METHODS: Consecutive patients below 16 years of age presenting to the uvea clinic of a tertiary eye care center were included prospectively through the period of July 2009-August 2013. Children with retinal vasculitis, exogenous endophthalmitis and masquerade syndromes were excluded from analysis. Uveitis was classified as per the nomenclature system adopted by the International Uveitis Study Group...
August 31, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28860868/feline-transmitted-staphylococcal-hyicus-endophthalmitis-after-clear-lens-extraction-a-case-report
#20
Shih-Chun Chao, Chia-Yi Lee, Chan-Wei Nien, Shih-Hao Tzeng, Hung-Yu Lin
BACKGROUND: Postoperative endophthalmitis is a dreaded postsurgery complication which may lead to legal blindness. In addition to typical risk factors, some minor episodes may also lead to the occurrence of endophthalmitis. The purpose of the current study was to report a case of acute postoperative endophthalmitis caused by Staphylococcus hyicus in a patient with a contact history of felines. CASE PRESENTATION: A 58-year-old Taiwanese female who had a history of contact with felines due to her occupation had received clear lens extraction surgery of the left eye on July 10, 2015...
2017: International Medical Case Reports Journal
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