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https://www.readbyqxmd.com/read/29684945/-it-s-going-to-be-extra-fun-analysis-of-an-atypical-case-of-teen-homicide-as-leisure-behavior
#1
D J Williams, Jolene Vincent
Recently, scholars in literary criminology and leisure sciences have begun to explore the role of broader leisure culture in potentially shaping fantasy development, planning, preparation, and execution in specific cases of expressive homicide. This brief report focuses on an unusual case of expressive homicide, wherein two teen offenders in Idaho collaborated to murder a female classmate as an intentional leisure activity. Prior to the murder, the offenders created a videotape describing how they planned to commit this (and additional) murders...
April 23, 2018: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/29684944/comparing-categorical-and-probabilistic-fingerprint-evidence
#2
Brandon Garrett, Gregory Mitchell, Nicholas Scurich
Fingerprint examiners traditionally express conclusions in categorical terms, opining that impressions do or do not originate from the same source. Recently, probabilistic conclusions have been proposed, with examiners estimating the probability of a match between recovered and known prints. This study presented a nationally representative sample of jury-eligible adults with a hypothetical robbery case in which an examiner opined on the likelihood that a defendant's fingerprints matched latent fingerprints in categorical or probabilistic terms...
April 23, 2018: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/29684939/loose-lipped-mobile-device-intelligent-personal-assistants-a-discussion-of-information-gleaned-from-siri-on-locked-ios-devices
#3
Graeme Horsman
The forensic analysis of mobile handsets is becoming a more prominent factor in many criminal investigations. Despite such devices frequently storing relevant evidential content to support an investigation, accessing this information is becoming an increasingly difficult task due to enhanced effective security features. Where access to a device's resident data is not possible via traditional mobile forensic methods, in some cases it may still be possible to extract user information via queries made to an installed intelligent personal assistant...
April 23, 2018: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/29684924/fixation-strength-of-pedicle-and-cortical-lumbar-vertebral-screws-after-laminectomy-a-cadaver-study
#4
Dai-Soon Kwak, Jae-Hyuk Shin, Ho-Jung Cho, Ho Guen Chang, Moon Soo Park, In-Sung Kim
BACKGROUND AND STUDY AIM:  Cortical screws were proposed as an alternative to the traditional pedicle screws. Diverse experimental results support the biomechanical superiority of cortical screws compared to pedicle screws. Laminectomy is often part of multilevel lumbar surgeries. Laminectomy might weaken the medial bony edge at the entry of the divergently oriented screw and, thereby, the screw purchase. This study investigated the biomechanical strength of lumbar cortical screw after laminectomy...
April 23, 2018: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/29684910/forensic-applications-of-supercritical-fluid-chromatography-mass-spectrometry
#5
REVIEW
Volodymyr Pauk, Karel Lemr
Achievements of supercritical fluid chromatography with mass spectrometric detection made in the field of forensic science during the last decade are reviewed. The main topics include analysis of traditional drugs of abuse (e.g. cannabis, methamphetamine) as well as new psychoactive substances (synthetic cannabinoids, cathinones and phenethylamines), doping agents (anabolic steroids, stimulants, diuretics, analgesics etc.) and chemical warfare agents. Control of food authenticity, detection of adulteration and identification of toxic substances in food are also pointed out...
April 11, 2018: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29684874/treatment-of-an-azo-dye-effluent-by-peroxi-coagulation-and-its-comparison-to-traditional-electrochemical-advanced-processes
#6
Edilson do Vale-Júnior, Djalma R da Silva, Ana S Fajardo, Carlos A Martínez-Huitle
Peroxi-coagulation (PC) is an interesting new process that has not been widely studied in the literature. This work presents the application of this technology to treat an azo dye synthetic effluent, studying the effect of different parameters including initial pH, current density (j), initial dye concentration and supporting electrolyte. The two former variables significantly affected the colour removal of the wastewater, followed by the initial dye concentration and the kind of electrolyte, in a lesser extent...
April 5, 2018: Chemosphere
https://www.readbyqxmd.com/read/29684824/a-review-of-human-biomonitoring-in-selected-southeast-asian-countries
#7
REVIEW
Zohar Barnett-Itzhaki, Marta Esteban López, Naveen Puttaswamy, Tamar Berman
Rapid development and industrialization in Southeast (SE) Asia has led to environmental pollution, potentially exposing the general population to environmental contaminants. Human biomonitoring (HBM), measurement of chemical and/or their metabolites in human tissues and fluids, is an important tool for assessing cumulative exposure to complex mixtures of chemicals and for monitoring chemical exposures in the general population. While there are national HBM programs in several developed countries, there are no such national programs in most of the SE Asian countries...
April 20, 2018: Environment International
https://www.readbyqxmd.com/read/29684618/everolimus-is-a-new-anti-cancer-molecule-metabolic-side-effects-as-lipid-disorders-and-hyperglycemia
#8
REVIEW
L Morviducci, F Rota, L Rizza, P Di Giacinto, S Ramponi, M R Nardone, C Tubili, A Lenzi, P Zuppi, R Baldelli
In the last few years, molecular targeted therapies have replaced traditional cytotoxic chemotherapy in the fight against many cancers to the extent that our understanding of tumor biology has become more sophisticated. This shift has markedly changed adverse event profiles, compared to cytotoxic chemotherapy, affecting a diverse range of organ systems. Everolimus was approved by the FDA in 2011 for the treatment of progressive pancreatic NE tumors (Yao, 2011; Jensenn, 2012). It is an inhibitor of mammalian target of rapamycin (mTOR) and exhibits antitumor activity via disruption of various signaling pathways and it's used in the treatment of advanced renal cell cancer, breast cancer and neuroendocrine tumors (NET); it's used also as anti-rejection agent for transplantation but with lower doses for anti-rejection (1...
April 20, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29684540/chemical-composition-antioxidant-anticholinesterase-antimicrobial-and-antibiofilm-activities-of-essential-oil-and-methanolic-extract-of-anthemis-stiparum-subsp-sabulicola-pomel-oberpr
#9
Ahmed Elkhalifa Chemsa, Amar Zellagui, Mehmet Öztürk, Ebru Erol, Ozgür Ceylan, Mehmet Emin Duru, Mesbah Lahouel
Anthemis species are traditionally used to treat infectious and inflammatory processes, among others clinical disturbances. In the current study, the chemical composition, the total phenolic and flavonoid contents, the antioxidant, anticholinesterase, antimicrobial, and antibiofilm activities of Anthemis stiparum subsp. sabulicola aerial parts methanolic extract (As-ME) and essential oil (As-EO) were investigated. The chemical composition of As-EO was established by GC-MS and GC-FID. Total phenolic and flavonoid contents of As-ME were spectrophotometrically determined...
April 20, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29684513/adult-chiari-i-malformations-an-analysis-of-surgical-risk-factors-and-complications-using-an-international-database
#10
Abhiraj D Bhimani, Darian R Esfahani, Steven Denyer, Ryan G Chiu, David Rosenberg, Ashley L Barks, Gregory D Arnone, Ankit I Mehta
BACKGROUND: Chiari I malformations are common in adults, and a frequent procedure in neurosurgical practice. Despite a number of studies, to date there is no consensus about the indications or surgical technique for this common condition. Growing emphasis on value-based care has emphasized reduction of readmissions and reoperations, and is particularly relevant in Chiari, which has traditionally been associated with a high complication rate. OBJECTIVE: To provide a contemporary surgical profile of risk factors and complications for Chiari I malformations in adults...
April 20, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29684494/quality-assessment-and-artificial-neural-networks-modeling-for-characterization-of-chemical-and-physical-parameters-of-potable-water
#11
Marjan Salari, Esmail Salami, Seyed Hossein Afzali, Majid Ehteshami, Gea Oliveri Conti, Zahra Derakhshan, Solmaz Nikbakht Sheibani
Today, due to the increase in the population, the growth of industry and the variety of chemical compounds, the quality of drinking water has decreased. Five important river water quality properties such as: dissolved oxygen (DO), total dissolved solids (TDS), total hardness (TH), alkalinity (ALK) and turbidity (TU) were estimated by parameters such as: electric conductivity (EC), temperature (T), and pH that could be measured easily with almost no costs. Simulate water quality parameters were examined with two methods of modeling include mathematical and Artificial Neural Networks (ANN)...
April 20, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29684403/white-matter-pathways-and-social-cognition
#12
REVIEW
Yin Wang, Athanasia Metoki, Kylie H Alm, Ingrid R Olson
There is a growing consensus that social cognition and behavior emerge from interactions across distributed regions of the "social brain". Researchers have traditionally focused their attention on functional response properties of these gray matter networks and neglected the vital role of white matter connections in establishing such networks and their functions. In this article, we conduct a comprehensive review of prior research on structural connectivity in social neuroscience and highlight the importance of this literature in clarifying brain mechanisms of social cognition...
April 20, 2018: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29684256/reirradiation-of-head-and-neck-cancer-using-modern-highly-conformal-techniques
#13
REVIEW
Jennifer C Ho, Jack Phan
Locoregional disease recurrence or development of a second primary cancer after definitive radiotherapy for head and neck cancers remains a treatment challenge. Reirradiation utilizing traditional techniques has been limited by concern for serious toxicity. With the advent of newer, more precise radiotherapy techniques, such as intensity-modulated radiotherapy (IMRT), proton radiotherapy, and stereotactic body radiotherapy (SBRT), there has been renewed interest in curative-intent head and neck reirradiation...
April 23, 2018: Head & Neck
https://www.readbyqxmd.com/read/29684177/a-novel-measure-of-ewe-efficiency-for-breeding-and-benchmarking-purposes
#14
N McHugh, T Pabiou, K McDermott, E Wall, D P Berry
Ewe efficiency has traditionally been defined as the ratio of litter weight to ewe weight; given the statistical properties of ratio traits, an alternative strategy is proposed in the present study. The concept of using the deviation in performance of an animal from the population norm has grown in popularity as a measure of animal-level efficiency. The objective of the present study was to define novel measures of efficiency for sheep which considers the combined weight of a litter of lambs relative to the weight of their dam, and vice versa...
April 19, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29684154/statistical-primer-propensity-score-matching-and-its-alternatives
#15
Umberto Benedetto, Stuart J Head, Gianni D Angelini, Eugene H Blackstone
Propensity score (PS) methods offer certain advantages over more traditional regression methods to control for confounding by indication in observational studies. Although multivariable regression models adjust for confounders by modelling the relationship between covariates and outcome, the PS methods estimate the treatment effect by modelling the relationship between confounders and treatment assignment. Therefore, methods based on the PS are not limited by the number of events, and their use may be warranted when the number of confounders is large, or the number of outcomes is small...
April 19, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29684146/genetic-structure-and-diversity-among-historic-and-modern-populations-of-the-sumatran-rhinoceros-dicerorhinus-sumatrensis
#16
Jessica R Brandt, Peter J Van Coeverden de Groot, Kelsey E Witt, Paige K Engelbrektsson, Kristofer M Helgen, Ripan S Malhi, Oliver A Ryder, Alfred L Roca
The Sumatran rhinoceros (Dicerorhinus sumatrensis), once widespread across Southeast Asia, now consists of as few as 30 individuals within Sumatra and Borneo. To aid in conservation planning, we sequenced 218 bp of control region mitochondrial (mt) DNA, identifying 17 distinct mitochondrial haplotypes across modern (N = 13) and museum (N = 26) samples. Museum specimens from Laos and Myanmar had divergent mtDNA, consistent with the placement of western mainland rhinos into the distinct subspecies D. s. lasiotis (presumed extinct)...
April 19, 2018: Journal of Heredity
https://www.readbyqxmd.com/read/29684016/correcting-for-batch-effects-in-case-control-microbiome-studies
#17
Sean M Gibbons, Claire Duvallet, Eric J Alm
High-throughput data generation platforms, like mass-spectrometry, microarrays, and second-generation sequencing are susceptible to batch effects due to run-to-run variation in reagents, equipment, protocols, or personnel. Currently, batch correction methods are not commonly applied to microbiome sequencing datasets. In this paper, we compare different batch-correction methods applied to microbiome case-control studies. We introduce a model-free normalization procedure where features (i.e. bacterial taxa) in case samples are converted to percentiles of the equivalent features in control samples within a study prior to pooling data across studies...
April 23, 2018: PLoS Computational Biology
https://www.readbyqxmd.com/read/29683995/cochlear-implantation-in-adults-with-asymmetric-hearing-loss-speech-recognition-in-quiet-and-in-noise-and-health-related-quality-of-life
#18
Douglas P Sladen, Matthew L Carlson, Brittany P Dowling, Amy P Olund, Melissa D DeJong, Alyce Breneman, Sara Hollander, Charles W Beatty, Brian A Neff, Colin L Driscoll
OBJECTIVE: To examine the possible speech recognition and health related quality of life (HRQoL) benefits of cochlear implantation among adults with asymmetric sensorineural hearing loss. STUDY DESIGN: Retrospective chart review, single-subject design. METHODS: A total of 45 adult cochlear implant recipients with asymmetric sensorineural hearing loss where performance for the best-aided condition exceeded 60% correct open set sentence recognition in quiet, and the implanted ear met traditional candidacy criteria...
March 26, 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29683948/hematopoietic-stem-cell-transplantation-from-unrelated-donors-in-2-cases-of-interleukin-10-receptor-deficiency-is-surgery-not-a-requirement
#19
Dilara F Kocacik Uygun, Vedat Uygun, Hayriye Daloğlu, Seda Öztürkmen, Gülsün Karasu, İsmail Reisli, Ersin Sayar, Hasan A Yüksekkaya, Erik-Oliver Glocker, Kaan Boztuğ, Akif Yeşilipek
Mutations in interleukin-10 and its receptors cause infantile inflammatory bowel disease (IBD), a hyperinflammatory disorder characterized by severe, treatment-refractory colitis, multiple abscesses, and enterocutaneous fistulas. Patients with infantile IBD often require several surgical interventions, including complete colectomy, and hematopoietic stem cell transplantation is currently the only known medical therapy. Traditionally, operative management has been preferred before stem cell transplantation because of the latter's increased susceptibility to procedural complications; however, surgical intervention could be delayed, and possibly reconsidered, because our 2 patients with infantile IBD demonstrated a rapid response to treatment via engraftment...
April 20, 2018: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29683925/short-term-8-weeks-high-intensity-interval-training-in-diseased-cohorts
#20
James E M Blackwell, Brett Doleman, Philip J J Herrod, Samuel Ricketts, Bethan E Phillips, Jonathan N Lund, John P Williams
BACKGROUND & AIM: Exercise training regimes can lead to improvements in measures of cardiorespiratory fitness (CRF), improved general health, and reduced morbidity and overall mortality risk. High intensity interval training (HIIT) offers a time-efficient approach to improve CRF in healthy individuals, but the relative benefits of HIIT compared to traditional training methods are unknown in across different disease cohorts. METHODS: This systematic review and meta-analysis compares CRF gains in randomised controlled trials of short-term (<8 weeks) HIIT vs...
April 21, 2018: Medicine and Science in Sports and Exercise
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