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Rosita Saraceno, Annunziata Dattola, Lucia Pietroleonardo, Rossella Pitocco, Monika Fida, Sergio Chimenti
No abstract text is available yet for this article.
August 2017: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
Mitchell L Ramsey, Darwin L Conwell, Phil A Hart
Chronic pancreatitis is a disease that leads to irreversible changes in the pancreatic morphology and function. The loss of function can lead to diabetes mellitus and exocrine pancreatic insufficiency. The inflammation and fibrosis can also lead to other complications including a chronic abdominal pain syndrome, metabolic bone disease, and pancretic cancer. This article reviews our current understanding of the mechanisms and management of these complications of chronic pancreatitis.
July 2017: Digestive Diseases and Sciences
Xinxin Cao, Jian Li, Wei Zhang, Minghui Duan, Tienan Zhu, Bing Han, Junling Zhuang, Huacong Cai, Miao Chen, Daobin Zhou
OBJECTIVE: To evaluate the safety of polyethylene glycol conjugated L-asparaginase (PEG-Asp) for patients with adult acute lymphoblastic leukemia (ALL) and T cell non-Hodgkin lymphoma (T-NHL). METHODS: A retrospective analysis was conducted on the clinical data of 101 young patients (≤40 years old) with ALL and T-NHL, diagnosed at Peking Union Medical College Hospital between January 2012 and June 2014. RESULTS: A total of 480 doses of PEG-Asp were administered in 44 cases with ALL and 57 patients with T-NHL...
March 2015: Zhonghua Xue Ye Xue za Zhi, Zhonghua Xueyexue Zazhi
F Bentivegna, V Cortese, S Bentivegna, F Cardì, P Di Mattia, G Barbera, A M Borzì, G Zanghì
OBJECTIVE: With improvement in methods, mortality after duodeno-cefalo pancreatectomy (DCP) has decreased to 5% even if complication rate is still high (30-50%). The pancreatic fistula still occurs in 25-50% of cases. Various methods of treating pancreatic stump have been proposed aimed to improve this rate. PATIENTS AND METHODS: The AA, surgeons of suburban hospital, have performed in five years, 2009-2013, 12 DCP. The pancreatic anastomosis has been in all cases an end-to-end duct-to-mucosa pancreatic-jejunostomy...
December 2014: European Review for Medical and Pharmacological Sciences
Mario Zovak, Dubravka Mužina Mišić, Goran Glavčić
Surgical resection of pancreatic cancer offers the only chance for prolonged survival. Pancretic resections are technically challenging, and are accompanied by a substantial risk for postoperative complications, the most significant complication being a pancreatic fistula. Risk factors for development of pancreatic leakage are now well known, and several prophylactic pharmacological measures, as well as technical interventions have been suggested in prevention of pancreatic fistula. With better postoperative care and improved radiological interventions, most frequently complications can be managed conservatively...
October 2014: Hepatobiliary Surgery and Nutrition
Petr Dítě, Ivo Novotný, Jan Lata, Jiří Vaníček, Martin Bulik
BACKGROUND/AIMS: This study presents the experience of its authors with endoscopic drainage treatment of pancreatic pseudocysts. The first part of the study offers a literature overview of the basic knowledge of pancreatic pseudocysts. The authors gradually deal with the individual types of pancreatic pseudocysts, the clinical picture, complications and diagnostics. Within the bounds of differential diagnostics the authors stress mainly the necessity of differentiating pancreatic pseudocysts from cystic tumors and benign cysts...
October 2013: Hepato-gastroenterology
E G Topuzov, Sh I Galeev, M A Rubtsov, Ia P Abdullaev, Ia V Kolosovskiĭ, Iu V Kniazeva
A retrospective analysis has been made of the results of the diagnosis and treatment of 71 patients having severe pancreatitis. As a result, factors were revealed which restrict the possibilities of conservative treatment associated with pessimistic prognosis of the disease. Among them there are pancretitis-specific organic abnormalities (pulmonary, cardio-vascular, renal dysfunctions), diffused pancreonecrosis and infection of destructive zones. All the parameters in question are included in the proposed model of prognosis of the fulminant course of pancreatitis having high diagnostic accuracy up to 88...
2012: Vestnik Khirurgii Imeni I. I. Grekova
Nicola Zanini, Adele Fornelli, Marta Fiscaletti, Carlo Fabbri, Raffaele Lombardi, Anna Maria Polifemo, Paola Baccarini, Michele Masetti, Elio Jovine
BACKGROUND: Pancreatic mucinous cystic lesions might develop malignancy if untreated, or could harbor malignancy at the time of the diagnosis. Many reports stated that cyst fluid carcinoembryonic antigen is an accurate diagnostic marker of pancreatic mucinous cysts. METHODS: A man with a incidental pancretic cystic lesion of 35 mm in diameter was admitted to our Department. CT and EUS did not reveal solid components, main duct was not dilated and cyst fluid CEA was very high (1445 ng/ml)...
May 2012: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
Hrvoje Iveković, Nadan Rustemović, Milorad Opacić, Ognjan Deban, Bosko Romic, Jasminka Jakić Razumović, Rajko Ostojić, Roland Pulanić, Boris Vucelić
Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is a relatively rare clinical entity with a main characteristic being mucus production. Extension of IPMN along pancretic ducts and mucus production lead to ductal obstruction and dilatation, resulting in recurrent episodes of acute pancreatitis. Molecular background of IPMN-a comprises several aberrations, with the K-ras gene mutation being the likely trigger that initiates further genetic changes. Due to its indolent nature, IPMN is most commonly diagnosed in the 7th decade of life...
January 2012: Lijec̆nic̆ki Vjesnik
Ergün Yücel, Yavuz Kurt, Yavuz Ozdemir, Ismet Gun, Mehmet Yildiz
Laparoscopic splenectomy became the gold standard recently for the removal of spleen. One of its rare indication is wandering spleen (WS). WS is characterized by incomplete fixation of the spleen. Patients usually have an asymptomatic abdominal mass. When they are symptomatic, abdominal pain with a mobile mass is the major finding. Laboratory data are nonspecific, but the diagnosis can be confirmed by imaging studies; computed tomography, magnetic resonance imaging, and ultrasonography are preferred modalities...
April 2012: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
Mansa Krishnamurthy, Jinming Li, Maia Al-Masri, Rennian Wang
Integrin-extracellular matrix interactions are important determinants of beta cell behaviours. The beta1 integrin is a well-known regulator of beta cell activities; however, little is known of its associated alpha subunits. In the present study, alphabeta1 integrin expression was examined in the rat insulinoma cell line (INS-1) to identify their role in beta cell survival and function. Seven alpha subunits associated with beta1 integrin were identified, including alpha1-6 and alphaV. Among these heterodimers, alpha3beta1 was most highly expressed...
December 2008: Journal of Cell Communication and Signaling
Atsushi Kanno, Kennichi Satoh, Kenji Kimura, Atsushi Masamune, Tohru Asakura, Shinichi Egawa, Makoto Sunamura, Mika Watanabe, Tooru Shimosegawa
Pancreatic arteriovenous malformation (AVM) is a relatively rare disease. Based on our literature search, 51 cases of pancreatic AVM have been reported since 1968. The gastrointestinal bleeding is the most common presenting symptom (24/51 cases [47%]). There were only 6 cases of pancreatitis in these cases. We describe 2 cases of acute pancretitis with pancreatic AVM. The patients who were diagnosed with acute pancreatitis were admitted to our hospital. Pancreatitis was considered to be caused by pancreatic AVM by some modalities of diagnostic imaging...
May 2006: Pancreas
Miodrag Jovanović, Dragoljub Bilanović, Radoje Colović, Nikica Grubor, Milenko Ugljesić
Choledochal cysts are rare congenital anomalies, mostly detected in adults. Pathogenesis of these cysts seems to be in anomalous junction between pancreatic and common bile duct, above the papillary sphincter and outside of the duodenal wall. The absence of the sphincter above the junction is followed by reflux of the pancreatic juice into the bile duct leading to dilatation and fibrous changes of bile duct wall. A 38-year-old female is presented in whom a choledochal cyst was found 11 years earlier, during the operation performed for obstructive jaundice, when cystojejunostomy with Roux-en Y Jejunal limb was carried out...
May 2004: Srpski Arhiv za Celokupno Lekarstvo
No abstract text is available yet for this article.
October 15, 1962: Polski Tygodnik Lekarski
No abstract text is available yet for this article.
January 1962: Maroc Médical
No abstract text is available yet for this article.
November 1960: American Journal of Gastroenterology
No abstract text is available yet for this article.
1961: Paediatria Japonica
J Martínez, J M Palazón, C Muñoz, M López, J Sánchez-Payá, R Laveda, M Pérez-Mateo
AIMS: We investigate the behaviour of endotoxin in patients with acute pancreatitis and its relationship with the development of complications. EXPERIMENTAL DESIGN: Prospective study. PATIENTS: We assessed plasmatic endotoxin and anti-core endotoxin antibodies (EndoCab IgG and IgM) levels on first and third days from admission in patients with acute pancreatitis episodes, classifying them as mild or severe according to Atlanta's criteria. RESULTS: Nineteen patients were included, seven with severe pancretitis (36...
July 2002: Revista Española de Enfermedades Digestivas
Xie-Ning Wu
No abstract text is available yet for this article.
June 1999: World Journal of Gastroenterology: WJG
M Wimmer, C Tag, H W Hofer
The secretory vesicles of some cells of the islets of Langerhans of the pancreas contain high amounts of immunoreactive tyrosine phosphatase of the PTP1B/TCPTP subfamily. The cells are located in the peripheral parts of the islets and were identified as glucagon- and pancreatic polypeptide-forming cells. The tyrosine phosphatase is also enriched in some of the somatostatin-producing cells but is not elevated either in insulin-producing B-cells or in the exocrine pancreas. Virtually the same patterns were found in pancretic tissues of rats, guinea pigs, pigs, and mice...
February 1999: Histochemistry and Cell Biology
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