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Elisabet Sundewall Thorén, Julie Hefting Pedersen, Nis Ove Jørnæs
Purpose: This paper describes the results from the iterative development and usability testing of an online audiological rehabilitation (OAR) program. The OAR was based on previous experience with Internet interventions and OAR. Method: The described OAR consisted of weekly learning modules, each of which had a specific topic and contained information and learning activities. A virtual coach, a trained audiologist, led the participants through the modules. The participants' feedback was collected using the "think-aloud" method in which the participants gave their feedback in a structured manner...
October 1, 2016: American Journal of Audiology
Taner Basturk, Ozlem Sari, Yener Koc, Nezaket Eren, Mahmoud Isleem, Ekrem Kara, Mustafa Sevinc, Tamer Sakaci, Elbis Ahbap, Nuri B Hasbal, Feyza B Caglayan, Abdulkadir Unsal
BACKGROUND: Neutrophilgelatinase-associated lipocalin (NGAL) has been proven to be a useful biomarker for early detection of acute kidney injury, but it is not known whether adding NGAL measurements to conventional risk factors will improve the risk assessment in the setting of chronic kidney disease (CKD). The aim of the present study was to examine the correlation of NGAL with early stage renal impairment in CKD and to evaluate its prognostic value in these subjects. METHODS: This is a prospective observational cohort study of 54 patients with early stage (stage 1-2) CKD...
October 21, 2016: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
Kristin Thomas, Catharina Linderoth, Marcus Bendtsen, Preben Bendtsen, Ulrika Müssener
BACKGROUND: Drinking of alcohol among university students is a global phenomenon; heavy episodic drinking is accepted despite several potential negative consequences. There is emerging evidence that short message service (SMS) text messaging interventions are effective to promote behavior change among students. However, it is still unclear how effectiveness can be optimized through intervention design or how user interest and adherence can be maximized. OBJECTIVE: The objective of this study was to develop an SMS text message-based intervention targeting alcohol drinking among university students using formative research...
October 20, 2016: JMIR MHealth and UHealth
Peter Arrow
: Limited information is available about dental service use, perceived need and perceived oral health status among Aboriginal populations in Western Australia. This study collected information from a convenience sample of people attending the opening ceremony of the 2014 National Aborigines and Islanders Day Observance Committee celebrations in Perth, Western Australia. METHODS: People who visited the Dental Health Services display stall at the event completed a questionnaire on dental service use, perceived need and self-rated oral health domains...
2016: Journal of Health Care for the Poor and Underserved
Fiona H McKay, Christina Cheng, Annemarie Wright, Jane Shill, Hugh Stephens, Mary Uccellini
INTRODUCTION: Increasing smartphones access has allowed for increasing development and use of smart phone applications (apps). Mobile health interventions have previously relied on voice or text-based short message services (SMS), however, the increasing availability and ease of use of apps has allowed for significant growth of smartphone apps that can be used for health behaviour change. This review considers the current body of knowledge relating to the evaluation of apps for health behaviour change...
October 18, 2016: Journal of Telemedicine and Telecare
H Felix Fischer, Matthias Rose
BACKGROUND: Recently, a growing number of Item-Response Theory (IRT) models has been published, which allow estimation of a common latent variable from data derived by different Patient Reported Outcomes (PROs). When using data from different PROs, direct estimation of the latent variable has some advantages over the use of sum score conversion tables. It requires substantial proficiency in the field of psychometrics to fit such models using contemporary IRT software. We developed a web application ( http://www...
October 19, 2016: BMC Medical Research Methodology
Casey A Dauw, Michael Borofsky, Nadya York, James E Lingeman
INTRODUCTION: The holmium laser has revolutionized the practice of minimally invasive endoscopy for kidney stones. Recently, a novel, rigid hand-piece for use in percutaneous nephrolithotomy (PCNL) that couples the holmium laser with suction has been developed. To date, there exists limited data regarding the usability and ergonomics of such treatment systems. We thus sought to compare surgeon-rated usability with three different suction laser hand-pieces in a porcine model. METHODS: We performed bilateral reverse PCNL on 4 female domestic farm pigs...
October 19, 2016: Journal of Endourology
J D Burgess, C M Cameron, L Cuttle, Z Tyack, R M Kimble
OBJECTIVE: With the popularity of the Internet as a primary source of health-related information, the aim of this website content analysis was to assess the accuracy and quality of burn first aid information available on the Internet. METHODS: Using the search term 'burn first aid' in four popular search engines, the first 10 websites from each search engine were recorded. From a total of 40 websites recorded, 14 websites were evaluated after removing duplicates...
October 15, 2016: Burns: Journal of the International Society for Burn Injuries
Angeline Traynor, Eimear Morrissey, Jonathan Egan, Brian E McGuire
BACKGROUND: Resource and geographic barriers are the commonly cited constraints preventing the uptake of psychological treatment for chronic pain management. For adults, there is some evidence to support the use of information and communication technology (ICT) as a mode of treatment delivery. However, mixed findings have been reported for the effectiveness and acceptability of psychological interventions delivered using information and communication technology for children and adolescents...
October 18, 2016: Systematic Reviews
Renée J F van den Heuvel, Monique A S Lexis, Luc P de Witte
The aim of this study was to explore the application of the IROMEC (Interactive social RObotic Mediators as Companions) robot to support play for children with severe physical disabilities in rehabilitation and special education. Within a 2-month pilot study, physically disabled children with a developmental age between 2 and 8 years participated in sessions with the robot. A combination of qualitative and quantitative outcome measures was used to collect data on aspects of feasibility, usability, barriers for the child as well as the therapist and an indication of the effects on playfulness and the achievement of therapeutic and educational goals...
October 17, 2016: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
Fabian B H Rehm, Shuxiong Chen, Bernd H A Rehm
Enzymes are used as biocatalysts in a vast range of industrial applications. Immobilization of enzymes to solid supports or their self-assembly into insoluble particles enhances their applicability by strongly improving properties such as stability in changing environments, re-usability and applicability in continuous biocatalytic processes. The possibility of co-immobilizing various functionally related enzymes involved in multistep synthesis, conversion or degradation reactions enables the design of multifunctional biocatalyst with enhanced performance compared to their soluble counterparts...
October 14, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Víctor López-Jaquero, Arturo C Rodríguez, Miguel A Teruel, Francisco Montero, Elena Navarro, Pascual Gonzalez
Tele-rehabilitation is one of the main domains where Information and Communication Technologies (ICT) have been proven useful to move healthcare from care centers to patients' home. Moreover, patients, especially those carrying out a physical therapy, cannot use a traditional Window, Icon, Menu, Pointer (WIMP) system, but they need to interact in a natural way, that is, there is a need to move from WIMP systems to Post-WIMP ones. Moreover, tele-rehabilitation systems should be developed following the context-aware approach, so that they are able to adapt to the patients' context to provide them with usable and effective therapies...
October 13, 2016: Sensors
Amir Rabani
The market for process instruments generally requires low cost devices that are robust, small in size, portable, and usable in-plant. Ultrasonic torsional guided wave sensors have received much attention by researchers for measurement of viscosity and/or density of fluids in recent years. The supporting electronic systems for these sensors providing many different settings of sine-wave signals are bulky and expensive. In contrast, a system based on bursts of square waves instead of sine waves would have a considerable advantage in that respect and could be built using simple integrated circuits at a cost that is orders of magnitude lower than for a windowed sine wave device...
October 12, 2016: Sensors
Masafumi Nishizawa
Until the early part of the 1980 s, home blood pressure (BP) was measured mainly by devices based on the Korotkoff method, in which Korotkoff sounds are detected by a microphone set in a cuff as the BP values are taken. However, when the cuff is not wound in the right place, it causes misalignment between the microphone and an artery, leading to inaccurate measurements. Noise from outside the cuff is also a problem.A mercury sphygmomanometer is generally used with the Korotkoff method. However, mercury mines, mercury use and mercury disposal are receiving increasing attention, and the Minamata Convention on Mercury treaty was adopted in 2013...
September 2016: Journal of Hypertension
Hsiao-Yen Hsieh, Richard Henker, Dianxu Ren, Wan-Yi Chien, Jia-Ping Chang, Lifan Chen, Patricia K Tuite
PURPOSE/OBJECTIVES: An efficient but comprehensive documentation system is essential for reducing nursing workload and ensuring adequate time for direct patient care. A "focus" is a nursing diagnosis or patient problem. The purpose of this project is to review and revise the focuses in the electronic charting system and to develop new focuses for documentation of clinical pathways. In addition, this project evaluated the impact of these changes on time required for documentation and nurse satisfaction...
November 2016: Clinical Nurse Specialist CNS
Carola Borries, Aaron A Sandel, Andreas Koenig, Eduardo Fernandez-Duque, Jason M Kamilar, Caroline R Amoroso, Robert A Barton, Joel Bray, Anthony Di Fiore, Ian C Gilby, Adam D Gordon, Roger Mundry, Markus Port, Lauren E Powell, Anne E Pusey, Amanda Spriggs, Charles L Nunn
Recent decades have seen rapid development of new analytical methods to investigate patterns of interspecific variation. Yet these cutting-edge statistical analyses often rely on data of questionable origin, varying accuracy, and weak comparability, which seem to have reduced the reproducibility of studies. It is time to improve the transparency of comparative data while also making these improved data more widely available. We, the authors, met to discuss how transparency, usability, and reproducibility of comparative data can best be achieved...
September 2016: Evolutionary Anthropology
Timo J Autio, Timo Koskenkorva, Tuomo K Leino, Petri Koivunen, Olli-Pekka Alho
OBJECTIVE: To illuminate the pathophysiology of acute rhinosinusitis (ARS) with sequential monitoring of inflammatory biomarkers during an ARS episode and to clarify their diagnostic usability in bacterial ARS. STUDY DESIGN: Inception cohort study with 50 conscripts with ARS. METHODS: We collected peripheral blood high-sensitive C-reactive protein (hs-CRP), white blood cell (WBC), procalcitonin, and nasal nitric oxide (nNO) counts at 2 to 3 and 9 to 10 days of symptoms during an ARS episode...
October 18, 2016: Laryngoscope
Jan Klocke, Katharina Kopetschke, Anna-Sophie Grießbach, Valerie Langhans, Jens Y Humrich, Robert Biesen, Duska Dragun, Andreas Radbruch, Gerd-Rüdiger Burmester, Gabriela Riemekasten, Philipp Enghard
Renal infiltration of inflammatory cells contributes to the pathogenesis of Lupus nephritis (LN). Current knowledge on the recruitment mechanisms relies mainly on findings in rodent models. Here, we assess various chemokine pathways in human LN by comparing urinary chemokine concentrations (in 25 patients with acute LN and in 78 lupus patients without active LN) with the expression of corresponding chemokine receptors on urinary leukocytes (in ten acute LN patients). Nine urinary chemokines were significantly elevated in LN patients and correlated with renal disease activity and urinary cell counts; however, their concentrations displayed considerable interindividual heterogeneity...
October 18, 2016: European Journal of Immunology
Anees A Ansari, Abdul K Parchur, Brijesh Kumar, S B Rai
The design of nanostructured materials with highly stable water-dispersion and luminescence efficiency is an important concern in nanotechnology and nanomedicine. In this paper, we described the synthesis and distinct surface modification on the morphological structure and optical (optical absorption, band gap energy, excitation, emission, decay time, etc.) properties of highly crystalline water-dispersible CaF2:Ce/Tb nanocrystals (core-nanocrystals). The epitaxial growth of inert CaF2 and silica shell, respectively, on their surface forming as CaF2:Ce/Tb@CaF2 (core/shell) and CaF2:Ce/Tb@CaF2@SiO2 (core/shell/SiO2) nanoarchitecture...
December 2016: Journal of Materials Science. Materials in Medicine
Benjamin Kick, Samantha Hensler, Florian Praetorius, Hendrik Dietz, Dirk Weuster-Botz
The bacteriophage M13 has found frequent applications in nanobiotechnology due to its chemically and genetically tunable protein surface and its ability to self-assemble into colloidal membranes. Additionally, its single-stranded (ss) genome is commonly used as scaffold for DNA origami. Despite the manifold uses of M13, upstream production methods for phage and scaffold ssDNA are underexamined with respect to future industrial usage. Here, the high-cell-density phage production with Escherichia coli as host organism was studied in respect of medium composition, infection time, multiplicity of infection and specific growth rate...
October 17, 2016: Biotechnology and Bioengineering
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