Tzu-Chan Hong, Emad M El-Omar, Yu-Ting Kuo, Jeng-Yih Wu, Mei-Jyh Chen, Chieh-Chang Chen, Yu-Jen Fang, Alex Hwong Ruey Leow, Hong Lu, Jaw-Town Lin, Yu-Kang Tu, Yoshio Yamaoka, Ming-Shiang Wu, Jyh-Ming Liou
BACKGROUND: We previously showed rising primary antibiotic resistance of Helicobacter pylori during 1990-2015 in the Asia-Pacific region. However, whether primary antibiotic resistance continues to rise is unknown. Therefore, we aimed to assess the latest prevalence of H pylori antibiotic resistance in this region. METHODS: We did an updated systematic review and meta-analysis of observational studies and randomised controlled trials published in PubMed, Embase, and Cochrane Library between Jan 1, 1990, and July 12, 2023...
January 2024: Lancet. Gastroenterology & Hepatology