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Helicobacter pylori guidelines

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https://www.readbyqxmd.com/read/29789650/use-of-dna-flow-cytometry-in-the-diagnosis-risk-stratification-and-management-of-gastric-epithelial-dysplasia
#1
Kwun Wah Wen, Peter S Rabinovitch, Danning Huang, Aras N Mattis, Gregory Y Lauwers, Won-Tak Choi
The natural history of gastric epithelial dysplasia and the consequential surveillance strategies are not well defined in the West. To date, the diagnosis relies on morphology, and no reliable adjunct methods, either immunohistochemical or molecular, have reproducibly been able to confirm the diagnosis and/or risk stratify gastric epithelial dysplasia. Yet, such a tool would be useful in confirming the diagnosis, and developing objective and rational surveillance guidelines. DNA flow cytometry was performed using formalin-fixed paraffin-embedded gastric tissue from 23 cases of high-grade dysplasia and 38 cases of low-grade dysplasia...
May 22, 2018: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/29785564/helicobacter-pylori-infection-in-pediatric-patients-update-on-diagnosis-and-eradication-strategies
#2
REVIEW
Kallirroi Kotilea, Nicolas Kalach, Matjaž Homan, Patrick Bontems
Helicobacter pylori infection is acquired mainly in childhood and remains an essential cause of peptic ulcer disease and gastric cancer. This article provides commentary on the last ESPGHAN/NASPGHAN guidelines and on publications made after the consensus conference of 2015. The majority of infected children are asymptomatic and pediatric studies do not support a role for H. pylori in functional disorders such as recurrent abdominal pain. The role of H. pylori infection in failure to thrive, children's growth, type I diabetes mellitus (T1DM), and celiac disease remains controversial...
May 22, 2018: Paediatric Drugs
https://www.readbyqxmd.com/read/29682242/eradication-of-helicobacter-pylori-in-iran-a-review
#3
REVIEW
Hafez Fakheri, Mehdi Saberi Firoozi, Zohreh Bari
Helicobacter pylori (H. pylori) infection is one of the most common bacterial infections, affecting almost half of the world's population. It is associated with peptic ulcer disease, gastric adenocarcinoma, and lymphoma. In Iran, the prevalence of H. pylori infection has been reported to be between 36% and 90% in different geographic regions. Several studies have assessed the efficacy of different therapeutic options for firstline and second-line H. pylori eradication in Iran; however, the results are conflicting...
January 2018: Middle East Journal of Digestive Diseases
https://www.readbyqxmd.com/read/29669681/the-diagnosis-and-treatment-of-functional-dyspepsia
#4
Ahmed Madisch
BACKGROUND: Functional dyspepsia (FD) is one of the more common functional disorders, with a prevalence of 10-20%. It affectsthe gastrointestinal tract. METHODS: This article is based on publications retrieved by a selective search of PubMed, with special attention to controlled trials, guidelines, and reviews. RESULTS: Typical dyspeptic symptoms in functional dyspepsia include epigastric pain, sensations of pressure and fullness, nausea, and early subjective satiety...
March 30, 2018: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29668771/ivth-brazilian-consensus-conference-on-helicobacter-pylori-infection
#5
Luiz Gonzaga Vaz Coelho, James Ramalho Marinho, Robert Genta, Laercio Tenório Ribeiro, Maria do Carmo Friche Passos, Schlioma Zaterka, Paulo Pimentel Assumpção, Alfredo José A Barbosa, Ricardo Barbuti, Lucia Libanês Braga, Helenice Breyer, Aloisio Carvalhaes, Décio Chinzon, Marcelo Cury, Gerson Domingues, Jorge Luiz Jorge, Ismael Maguilnik, Frederico Passos Marinho, Joaquim Prado de Moraes-Filho
Significant progress has been obtained since the III Brazilian Consensus Conference on H. pylori infection held in 2012, in Bento Gonçalves, Brazil, and justify a fourth meeting to establish updated guidelines on the current management of H. pylori infection. Therefore, the Núcleo Brasileiro para Estudo do Helicobacter pylori e Microbiota (NBEHPM), association linked to Brazilian Federation of Gastroenterology (FBG) held its fourth meeting again in Bento Gonçalves, RS, Brazil, on August 25-27, 2017. Twenty-six delegates, including gastroenterologists, endoscopists, and pathologists from the five regions of Brazil as well as one international guest from the United States, participated in the meeting...
April 16, 2018: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/29606921/overview-of-current-concepts-in-gastric-intestinal-metaplasia-and-gastric-cancer
#6
David S Jencks, Jason D Adam, Marie L Borum, Joyce M Koh, Sindu Stephen, David B Doman
Gastric intestinal metaplasia is a precancerous change of the mucosa of the stomach with intestinal epithelium, and is associated with an increased risk of dysplasia and cancer. The pathogenesis to gastric cancer is proposed by the Correa hypothesis as the transition from normal gastric epithelium to invasive cancer via inflammation followed by intramucosal cancer and invasion. Multiple risk factors have been associated with the development of gastric intestinal metaplasia interplay, including Helicobacter pylori infection and associated genomics, host genetic factors, environmental milieu, rheumatologic disorders, diet, and intestinal microbiota...
February 2018: Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29600697/pharmacological-considerations-and-step-by-step-proposal-for-the-treatment-of-helicobacter-pylori-infection-in-the-year-2018
#7
Rinaldo Pellicano, Rocco M Zagari, Songhua Zhang, Giorgio M Saracco, Steven F Moss
Over the past 30 years, multidrug regimens consisting of a proton pump inhibitor (PPI) and two or three antibiotics have been used in treating Helicobacter pylori (H. pylori) infection. In clinical practice, the optimal regimen to cure H. pylori infection should be decided regionally. Considering the first treatment, the Maastricht V/Florence Consensus Report and the American College of Gastroenterology Clinical Management Guideline highlight that in countries with low clarithromycin resistance rates (<15%), an empiric clarithromycin-based regimen can be used...
March 30, 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/29566383/gastritis-can-cause-and-trigger-chronic-spontaneous-urticaria-independent-of-the-presence-of-helicobacter-pylori
#8
Semen Zheleznov, Galina Urzhumtseva, Natalia Petrova, Zhanna Sarsaniia, Nikolai Didkovskii, Tamara Dörr, Torsten Zuberbier
BACKGROUND/AIM: In chronic spontaneous urticaria (CSU), Helicobacter pylori (HP) has been discussed as a cause, but it is unknown whether the bacterium itself or concomitant inflammation is causing the urticaria. Our aim was to investigate HP and upper gastrointestinal lesions as signs of inflammation independently of each other in the pathogenesis of CSU. METHODS: A total of 36 prospectively enrolled CSU patients from Moscow were investigated by gastroscopy and screened for the presence of HP and/or upper gastrointestinal lesions...
2018: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/29559361/houston-consensus-conference-on-testing-for-helicobacter-pylori-infection-in-the-united-states
#9
Hashem B El-Serag, John Y Kao, Fasiha Kanwal, Mark Gilger, Frank LoVecchio, Steven F Moss, Sheila Crowe, Adam Elfant, Thomas Haas, Ron Hapke, David Y Graham
Despite guidelines for detection and treatment of Helicobacter pylori infection, recommendations to test patients before and after therapy are commonly not followed in the United States. At the Houston Consensus Conference, 11 experts on management of adult and pediatric patients with H. pylori, from different geographic regions of the United States, met to discuss key factors in diagnosis of H. pylori infection, including identification of appropriate patients for testing, effects of antibiotic susceptibility on testing and treatment, appropriate methods for confirmation of infection and eradication, and relevant health system considerations...
March 17, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29528162/antibiotics-resistance-of-helicobacter-pylori-in-children-with-upper-gastrointestinal-symptoms-in-hangzhou-china
#10
Xiaoli Shu, Guofeng Yin, Mingnan Liu, Kerong Peng, Hong Zhao, Mizu Jiang
BACKGROUND: The decreasing eradication rate of Helicobacter pylori is mainly because of the progressive increase in its resistance to antibiotics. Studies on antimicrobial susceptibility of H. pylori in children are limited. This study aimed to investigate the resistance rates and patterns of H. pylori strains isolated from children. MATERIALS AND METHODS: Gastric mucosa biopsy samples obtained from children who had undergone upper gastrointestinal endoscopy were cultured for H...
March 12, 2018: Helicobacter
https://www.readbyqxmd.com/read/29481383/pylera-and-sequential-therapy-for-first-line-helicobacter-pylori-eradication-a-culture-based-study-in-real-clinical-practice
#11
Giulia Fiorini, Angelo Zullo, Ilaria M Saracino, Luigi Gatta, Matteo Pavoni, Dino Vaira
BACKGROUND AND AIMS: Italian guideline suggests 10-day sequential or bismuth-based quadruple therapies for first-line Helicobacter pylori treatment. Comparison between these regimens is lacking. We assessed the efficacy of these therapies in clinical practice and evaluated the role of primary bacterial resistance toward clarithromycin and metronidazole. PATIENTS AND METHODS: Consecutive patients with H. pylori infection were enrolled. Bacterial culture with antibiotics susceptibility testing was attempted in all cases...
June 2018: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29480566/high-prevalence-of-helicobacter-pylori-clarithromycin-resistance-mutations-among-seattle-patients-measured-by-droplet-digital-pcr
#12
Sarah Talarico, Andrew S Korson, Christina K Leverich, Stephanie Park, Florencia G Jalikis, Melissa P Upton, Elizabeth Broussard, Nina R Salama
BACKGROUND: Treatment of Helicobacter pylori infection is often empiric; however, current guidelines for management of Helicobacter pylori infection advise against the use of standard triple therapy (clarithromycin, amoxicillin, and proton-pump inhibitor) when clarithromycin resistance exceeds 20%. We developed and tested a new culture-free assay to detect clarithromycin resistance-conferring mutations to determine the prevalence of H. pylori clarithromycin resistance in patients from the United States Pacific Northwest...
April 2018: Helicobacter
https://www.readbyqxmd.com/read/29458240/benign-and-malignant-gastroduodenal-diseases-associated-with-helicobacter-pylori-a-narrative-review-and-personal-remarks-in-2018
#13
György M Buzás
The subject of Helicobacter pylori continues to elicit worldwide interest in many research fields. Epidemiological data suggest that the prevalence of the infection is decreasing in Western/developed countries and even in some developing regions, but this is masked by the high prevalence in the most populous regions. Chronic gastritis, caused invariably by the bacterium, was again classified in Kyoto and Helicobacter pylori-associated gastritis was included as a distinct entity. The prevalence of peptic ulcers is decreasing, but bleeding ulcers are a challenging problem, with stable mortality levels even in the endoscopic era...
February 19, 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/29426621/update-on-the-management-of-helicobacter-pylori-infection-position-paper-from-the-catalan-society-of-digestology
#14
Jordi Sánchez Delgado, Pilar García-Iglesias, Llúcia Titó, Ignasi Puig, Montse Planella, Emili Gené, Joan Saló, Francesc Martínez-Cerezo, Javier Molina-Infante, Javier P Gisbert, Xavier Calvet
More than 30 years after its discovery, Helicobacter pylori (H. pylori) infection remains the most common cause of gastric and duodenal diseases. H. pylori is the leading cause of chronic gastritis, peptic ulcer, gastric MALT lymphoma and gastric adenocarcinoma. Several consensuses have recently been published on the management of H. pylori infection. The general guidelines of the Spanish consensus, the Toronto Consensus and the Maastricht V Consensus of 2016 are similar but concrete recommendations can vary significantly...
April 2018: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/29393168/endoscopic-submucosal-dissection-for-adenocarcinomas-of-the-esophagogastric-junction
#15
Yasuaki Nagami, Masaki Ominami, Koji Otani, Shuhei Hosomi, Fumio Tanaka, Koichi Taira, Noriko Kamata, Hirokazu Yamagami, Tetsuya Tanigawa, Masatsugu Shiba, Toshio Watanabe, Yasuhiro Fujiwara
BACKGROUND: Adenocarcinoma of the esophagogastric junction (EGJ) is uncommon in Eastern countries, including Japan, but it is believed that the incidence of EGJ adenocarcinoma will increase in Asia in the future due to the decreasing incidence of Helicobacter pylori infection. Endoscopic submucosal dissection (ESD) is a minimally invasive and curative treatment that allows precise pathological assessment. SUMMARY: Magnifying endoscopy with narrow-band imaging may be useful for differential diagnoses and for delineating the cancer margin of EGJ adenocarcinoma, but subsquamous carcinoma extension, which is the invasion of EGJ adenocarcinoma beneath the normal esophageal squamous epithelium, makes it difficult to detect cancer margins of the oral side in ESD for EGJ adenocarcinoma...
2018: Digestion
https://www.readbyqxmd.com/read/29392757/chronic-spontaneous-urticaria-in-children-a-systematic-review-on-interventions-and-comorbidities
#16
Hélène Cornillier, Bruno Giraudeau, Stéphane Munck, Florence Hacard, Annie-Pierre Jonville-Bera, Gwenaëlle d'Acremont, Bach-Nga Pham, Annabel Maruani
BACKGROUND: Chronic spontaneous urticaria (CSU) is not frequent in children. Management guidelines have been developed for adults and randomized controlled trials (RCTs) included teenagers aged 12-18, but data for children under age 12 are limited. We performed a systematic review to assess comorbidities in children <12 years old with CSU and the efficacy and safety of treatments. METHODS: We searched for original articles of epidemiologic and treatment data in children <12 years old with CSU that were published from 2005 to July 2016 in MEDLINE, EMBASE, CENTRAL, and LILACS...
May 2018: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/29353050/helicobacter-pylori-infection-an-update-for-the-internist-in-the-age-of-increasing-global-antibiotic-resistance
#17
REVIEW
Osama Siddique, Anais Ovalle, Ayesha S Siddique, Steven F Moss
Helicobacter pylori infects approximately half the world's population and is especially prevalent in the developing world. H. pylori is an important cause of global ill health due to its known etiological role in peptic ulcer disease, dyspepsia, gastric cancer, lymphoma, and more recently, recognized in iron deficiency anemia and idiopathic thrombocytopenic purpura. Increased antibiotic usage worldwide has led to antibiotic resistance among many bacteria, including H. pylori, resulting in falling success rates of first-line anti-H...
January 17, 2018: American Journal of Medicine
https://www.readbyqxmd.com/read/29327820/gastroenterology-today-between-certainties-and-news-a-meeting-held-in-turin-on-may-27-2017
#18
Rinaldo Pellicano, Davide G Ribaldone, Marco Astegiano, Luca Dughera, Edda Battaglia, Anna Morgando, Arrigo Arrigoni, Mauro Spandre, Mario Grassini, Giorgio M Saracco, Francis Mégraud
This special article reports on two crucial issues discussed during a meeting. The first was the updated management of Helicobacter pylori infection. This was approached taking into account the recent European Guidelines, with a focus on novelties in treatment. In particular, considering the increasing H. pylori antibiotic resistance to clarithromycin, in countries with a high clarithromycin resistance rate the bismuth-containing quadruple therapies should be preferred. The new formulation, with bismuth, metronidazole, and tetracycline contained in a single capsule (three-in-one), has shown exciting results both in naive and in non-responder patients...
January 10, 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/29305814/histopathology-findings-in-patients-undergoing-laparoscopic-sleeve-gastrectomy
#19
Ammiel Martínez Canil, Angelo Iossa, Pietro Termine, Daniela Caporilli, Vincenzo Petrozza, Gianfranco Silecchia
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) has gained popularity in the last 10 years for its good results in weight loss and comorbidity control. However, guidelines on the pathological examination of the specimen are lacking. The aim of this retrospective study was to determine the usefulness of the routine specimen examination when presurgery endoscopy (upper gastrointestinal endoscopy, UGIE) and multiple gastric biopsies are part of the preoperative work-up. METHODS: A retrospective review of records of the patients submitted to LSG between January 2012 and August 2017 was carried out...
January 5, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29302504/characteristics-of-upper-gastrointestinal-tract-involvement-in-korean-pediatric-crohn-s-disease-a-multicenter-study
#20
Ji Hyoung Park, Hye Na Nam, Ji-Hyuk Lee, Jeana Hong, Dae Yong Yi, Eell Ryoo, In Sang Jeon, Hann Tchah
Purpose: Crohn's disease (CD) can involve any site of the gastrointestinal tract (GIT). However, the characteristics of upper GIT involvement in CD are unclear, especially in the Eastern pediatric population. This study aimed to estimate the prevalence of upper GIT involvement and identify the clinical features of Korean children with CD. Methods: This was a retrospective multicenter cohort study that included 52 pediatric patients with CD who underwent esophagogastroduodenoscopy and biopsy...
December 2017: Pediatric Gastroenterology, Hepatology & Nutrition
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