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https://www.readbyqxmd.com/read/29679294/gender-differences-in-home-based-cardiac-rehabilitation-of-post-percutaneous-coronary-intervention-patients
#1
Yong Hwan Kim, Wi-Young So
Cardiac rehabilitation (CR) is a structured program for the prevention of secondary cardiovascular disease (CVD) and related diseases, such as hypertension, diabetes, and obesity. This study aimed to investigate whether there are gender differences after 9 months of home-based cardiac rehabilitation program in post-percutaneous coronary intervention patients. A total of 114 (58.29 ± 10.33 years) men and 30 (60.90 ± 9.32 years) women were enrolled in the CR program. The program included three visits: initial, 4th month (follow-up), and 9th month (final) visits at a CR center...
April 20, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29678837/infections-and-risk-of-peripartum-stroke-during-delivery-admissions
#2
Eliza C Miller, Marisa Gallo, Erin R Kulick, Alexander M Friedman, Mitchell S V Elkind, Amelia K Boehme
BACKGROUND AND PURPOSE: Peripartum strokes during delivery admissions are rare but have high maternal morbidity. Infections have been proposed as a possible stroke trigger. We hypothesized that women who had infections diagnosed at the time of delivery admission would have higher risk of stroke during their delivery hospitalization. METHODS: We conducted a case-control study using state inpatient administrative databases for California (2007-2011), Florida (2009-2011), and New York (2009-2011)...
April 20, 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29678158/dexmedetomidine-infusion-as-an-analgesic-adjuvant-during-laparoscopic-%C3%B1-holecystectomy-a-randomized-controlled-study
#3
Kateryna Bielka, Iurii Kuchyn, Volodymyr Babych, Kseniia Martycshenko, Oleksii Inozemtsev
BACKGROUND: Dexmedetomidine (DEX) has sedative, sympatholytic and analgesic effects and might be beneficial if used as an adjuvant to: improve analgesia; modulate haemodynamic responses to intubation and pneumoperitoneum and; reduce the number of opioid-associated adverse events. The aim of this study was to evaluate the efficacy and safety of DEX infusion during elective laparoscopic cholecystectomy (LC). METHODS: A randomized, single-centre, parallel-group, placebo-controlled study was carried out between May 2016 and June 2017...
April 20, 2018: BMC Anesthesiology
https://www.readbyqxmd.com/read/29678139/pulmonary-hemosiderosis-in-children-with-down-syndrome-a-national-experience
#4
Aurelia Alimi, Jessica Taytard, Rola Abou Taam, Véronique Houdouin, Aude Forgeron, Marc Lubrano Lavadera, Pierrick Cros, Isabelle Gibertini, Jocelyne Derelle, Antoine Deschildre, Caroline Thumerelle, Ralph Epaud, Philippe Reix, Michael Fayon, Sylvie Roullaud, Françoise Troussier, Marie-Catherine Renoux, Jacques de Blic, Sophie Leyronnas, Guillaume Thouvenin, Caroline Perisson, Aimé Ravel, Annick Clement, Harriet Corvol, Nadia Nathan
BACKGROUND: Pulmonary hemosiderosis is a rare and complex disease in children. A previous study from the French RespiRare® network led to two important findings: 20% of the children presented with both pulmonary hemosiderosis and Down syndrome (DS), and at least one tested autoantibody was found positive in 50%. This study investigates the relationships between pulmonary hemosiderosis and DS. METHODS: Patients younger than 20 years old and followed for pulmonary hemosiderosis were retrieved from the RespiRare® database...
April 20, 2018: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/29675383/clinical-outcomes-of-patterned-laser-trabeculoplasty-as-adjuvant-therapy-in-open-angle-glaucoma-and-ocular-hypertension
#5
Gustavo Espinoza, Leonardo Castellanos, Ignacio Rodriguez-Una, Paul Anthony Camacho, Juan Camilo Parra
AIM: To assess the efficacy and safety of patterned laser trabeculoplasty (PLT) as an adjunctive treatment in open angle glaucoma (OAG) or ocular hypertension (OHT) patients who were under antiglaucoma medical treatment. METHODS: This study was a retrospective review of primary or secondary OAG patients and OHT patients with medically uncontrolled (≥18 mm Hg) intraocular pressure (IOP) who underwent 360° PLT from June 2016 to August 2016. Follow-up visits at week 1, and 1, 3 and 6mo were performed...
2018: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29675258/livedo-reticularis-a-cutaneous-clue-to-an-underlying-endocrine-crisis
#6
Natasha Shrikrishnapalasuriyar, Mirena Noyvirt, Philip Evans, Bethan Gibson, Elin Foden, Atul Kalhan
A 54-year-old woman was admitted to hospital with a presumed allergic reaction to a single dose of amoxicillin given for a suspected upper respiratory tract infection. She complained of chest tightness although there was no wheeze or stridor. On examination, she was pyrexial, tachycardic, hypertensive and had a diffuse mottled rash on her lower limbs. Her initial investigations showed raised inflammatory markers. She was treated in the intensive care for a presumed anaphylactic reaction with an underlying sepsis...
2018: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/29673919/-pseudo-pheochromocytoma-induced-by-professional-stress-a-case-report
#7
M Chihaoui, A Jaidane, M Yazidi, I Oueslati, F Chaker, O Rejeb, H Slimane
INTRODUCTION: An elevation of plasma or urinary catecholamines or their metabolites in the context of a suspicion of a secondary hypertension associated with paroxysms generally leads to the diagnosis of pheochromocytoma. However, this is not always true. CASE REPORT: We report the case of a 39-year old man with a severe hypertension that was resistant to drug therapy and associated with paroxysms. Urinary fractioned metanephrines were elevated. However, no tumor could be found on tomodensitometry and MIBG scintigraphy...
April 16, 2018: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/29673852/national-trends-and-outcomes-of-hospitalizations-for-pulmonary-hypertension-in-spain-2001-2014
#8
Javier de-Miguel-Díez, Ana López-de-Andrés, Valentin Hernandez-Barrera, Isabel Jimenez-Trujillo, Jose María de-Miguel-Yanes, Manuel Mendez-Bailón, Rodrigo Jimenez-Garcia
OBJECTIVE: To assess changes in incidence, diagnostic procedures, comorbidity profiles, length of hospital stay (LOHS), costs, and in-hospital mortality (IHM) for patients hospitalized with pulmonary hypertension (PH). METHODS: We included patients hospitalized with PH in Spain from 2001 to 2014. The data were collected from the National Hospital Discharge Database. RESULTS: We included 644,436 discharges (43.31% males and 56.09% females) admitted for primary PH (8...
April 7, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29672871/sex-differences-in-the-contemporary-management-of-hiv-patients-admitted-for-acute-myocardial-infarction
#9
Gbolahan O Ogunbayo, Katrina Bidwell, Naoki Misumida, Le Dung Ha, Ahmed Abdel-Latif, Claude S Elayi, Susan Smyth, Adrian W Messerli
BACKGROUND: Studies have reported sex differences in the management of patients with acute myocardial infarction (AMI) in the general population. This observational study is designed to evaluate whether sex differences exist in the contemporary management of human immunodeficiency virus (HIV) patients admitted for diagnosis of AMI. HYPOTHESIS: There is no difference in management of HIV patients with AMI. METHODS: Using the National Inpatient Sample database, we identified patients with a primary diagnosis of AMI and a secondary diagnosis of HIV...
April 19, 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29672249/urinary-tract-infection-by-strongyloides-stercoralis-a-case-report
#10
Nilo Manoel Pereira Vieira Barreto, Joelma Nascimento de Souza, Weslei Almeida Costa Araujo, Nadia Andrade Khouri, Ernesto Pereira de Oliveira, Márcia Cristina Aquino Teixeira, Neci Matos Soares
The objective of this study was to report a case of a hydronephrotic patient with Strongyloides stercoralis infection, with discharge of rhabditoid larva exclusively in urine. In 2013, a 72-yr-old, male patient, hypertensive, obese and diagnosed with hydronephrosis secondary to renal calculi, reported lumbar pain, polyuria, polaciuria and dysuria, as well as frequent urinary tract infections. The microscopic analysis of urine sediment showed the presence of S. stercoralis rabditoid larva. However, parasitological examinations by Baermann-Moraes, agar plate culture and spontaneous sedimentation, performed with 3 fecal samples on alternate days had negative results...
April 19, 2018: Journal of Parasitology
https://www.readbyqxmd.com/read/29671868/secondary-prevention-and-lifestyle-indices-after-stroke-in-a-long-term-perspective
#11
A C Jönsson, H Delavaran, H Lövkvist, M Baturova, S Iwarsson, A Ståhl, B Norrving, A Lindgren
OBJECTIVES: To describe the long-term perspective regarding prevalence of risk factors, secondary stroke prevention, and lifestyle indices after stroke. METHODS: From a population-based one-year cohort (n = 416), we performed an observational study of 145 survivors at 16 months and 10 years after stroke (age 27-97 years) regarding secondary prevention including reaching acceptable treatment goals; nutritional status with focus on underweight; and the lifestyle indices: living situation, level of dependence, and self-assessed health condition...
April 19, 2018: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/29671813/association-of-anthropometric-indices-of-obesity-with-hypertension-in-chinese-elderly-an-analysis-of-age-and-gender-differences
#12
Qian Wang, Lingzhong Xu, Jiajia Li, Long Sun, Wenzhe Qin, Gan Ding, Jing Zhu, Jiao Zhang, Zihang Yu, Su Xie
This study aims to explore the association of anthropometric indices of obesity with hypertension in Chinese elderly and its possible gender and age differences. A total of 7070 adults age 60 or older were interviewed in a cross-sectional study conducted in 2017. Anthropometric indices for each participant were measured by using standard methods of trained doctoral/master students. We performed two binary logistic regression models to examine the association of the nine different anthropometric indices and hypertension by gender...
April 19, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29671295/monitoring-the-injured-brain
#13
Anna T Mazzeo, Deepak K Gupta
Traumatic brain injury can be defined as the most complex disease in the most complex organ. When an acute brain injury occurs, several pathophysiological cascades are triggered, leading to further exacerbation of the primary damage. A number of events potentially occurring after TBI can compromise the availability or utilization of energy substrates in the brain, ultimately leading to brain energy crisis. The frequent occurrence of secondary insults in the acute phase after TBI, such as intracranial hypertension, hypotension, hypoxia, hypercapnia, hyperthermia, seizures, can then increase cerebral damage, and adversely affect outcome...
April 18, 2018: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/29667175/first-line-drugs-for-hypertension
#14
REVIEW
James M Wright, Vijaya M Musini, Rupam Gill
BACKGROUND: This is the first update of a review published in 2009. Sustained moderate to severe elevations in resting blood pressure leads to a critically important clinical question: What class of drug to use first-line? This review attempted to answer that question. OBJECTIVES: To quantify the mortality and morbidity effects from different first-line antihypertensive drug classes: thiazides (low-dose and high-dose), beta-blockers, calcium channel blockers, ACE inhibitors, angiotensin II receptor blockers (ARB), and alpha-blockers, compared to placebo or no treatment...
April 18, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29666033/antidiabetics-usage-in-type-2-diabetes-mellitus-are-prescribing-guidelines-adhered-to-a-single-centre-study
#15
Viviane Khalil, Christy Sajan, Tiffany Tsai, David Ma
AIM: The primary aim of this study was to examine the prescribing patterns of antidiabetic agents (AA) in this hospital according to current prescribing contraindications (PCI). The secondary aims are to assess factors affecting the prescribing of AA and to evaluate the pharmacist impact on their prescribing. METHOD: A retrospective cross sectional study was performed to review all prescribed AA over a 3 month period. Data extracted from medical records included: patients' demographics, management and pharmacists' interventions...
April 11, 2018: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29662638/an-open-label-single-armed-exploratory-study-of-apatinib-a-novel-vegfr-2-tyrosine-kinase-inhibitor-in-patients-with-relapsed-or-refractory-non-hodgkin-lymphoma
#16
Ling Li, Sa Xiao, Lei Zhang, Xin Li, Xiaorui Fu, Xinhua Wang, Jingjing Wu, Zhenchang Sun, Xudong Zhang, Yu Chang, Feifei Nan, Jiaqin Yan, Zhaoming Li, Mengyuan Shi, Ken H Young, Mingzhi Zhang
Background: Apatinib, a novel small molecule vascular endothelial growth factor receptor-2 (VEGFR-2) tyrosine kinase inhibitor, have shown remarkable efficacy in many solid cancers. But evidence of antitumor activity in patients with lymphoma is still limited. We conducted an open-label, single-armed, exploratory study in relapse or refractory non-Hodgkin lymphoma patients for the efficacy and safety of apatinib. Experimental design: Patients with relapse or refractory non-Hodgkin patients meet the criteria were eligible for enrollment...
March 23, 2018: Oncotarget
https://www.readbyqxmd.com/read/29661697/cardiovascular-disease-risk-in-sexual-minority-women-18-59-years-old-findings-from-the-national-health-and-nutrition-examination-survey-2001-2012
#17
Billy A Caceres, Abraham A Brody, Perry N Halkitis, Caroline Dorsen, Gary Yu, Deborah A Chyun
OBJECTIVE: Sexual minority women (lesbian and bisexual) experience significant stigma, which may increase their cardiovascular disease (CVD) risk. The purpose of this study was to examine the prevalence of modifiable risk factors for CVD (including mental distress, health behaviors, blood pressure, glycosylated hemoglobin, and total cholesterol) and CVD in sexual minority women compared with their heterosexual peers. MATERIALS AND METHODS: A secondary analysis of the National Health and Nutrition Examination Survey (2001-2012) was conducted...
April 13, 2018: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
https://www.readbyqxmd.com/read/29659717/statin-treatment-is-associated-with-a-neutral-effect-on-health-related-quality-of-life-among-community-dwelling-octogenarian-men
#18
Timo E Strandberg, Annele Urtamo, Juuso Kähärä, Arto Y Strandberg, Kaisu H Pitkälä, Hannu Kautiainen
Background: Statin treatment is common among 80+ people, but little is known about statin effects on health-related quality of life (HRQoL) in this oldest age group. Methods: In the Helsinki Businessmen Study (HBS), men born 1919 to 1934 (original n=3490), have been followed-up since the 1960s. In 2015, a questionnaire about lifestyle, diseases and medications, and including RAND-36/SF-36 HRQoL instrument was mailed to survivors. 612 men (72.6%) responded, 530 of them reporting their medications (98% community-living)...
April 12, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29658768/idiopathic-portal-hypertension-with-regard-to-thiopurine-treatment
#19
Salvador Machlab, Mireia Miquel, Mercedes Vergara
Idiopathic portal hypertension (IPH) is an infrequent adverse reaction to the use of thiopurines that tends to be overlooked. Herein, we present a patient with ileocolic Crohn's disease treated with azathioprine who presented ascites, esophageal varices and splenomegaly without any signs of liver cirrhosis. A portal hemodynamics study revealed a normal portosystemic gradient compatible with presinusoidal portal hypertension. Finally, IPH was diagnosed after a liver biopsy. IPH secondary to thiopurines is due to a 6-thioguanine nucleotide (6-TGN)-dependent reaction and occurs predominantly between three months and three years after the start of treatment...
April 16, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29658086/coupling-of-lipoperoxidation-reactions-with-changes-in-arterial-blood-pressure-in-hypertensive-isiah-rats-under-conditions-of-chronic-stress
#20
L I Kolesnikova, L V Rychkova, L R Kolesnikova, M A Darenskaya, L V Natyaganova, L A Grebenkina, L I Korytov, S I Kolesnikov
Mature normotensive male WAG rats and stress-sensitive hypertensive ISIAH rats were exposed to "everyday life stress" modelled by alternation of immobilization and adaptation. Increased LPO intensity (increased content of substrates with unsaturated double bonds and primary and secondary LPO products) and reduced content of some antioxidant protection components (reduced retinol level and GSH/GSSG ratio) were revealed in the blood of ISIAH rats. These changes correlated with elevated mean BP. The results can reflect the significant role of LPO changes in the pathogenesis of stress-induced arterial hypertension...
April 16, 2018: Bulletin of Experimental Biology and Medicine
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