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https://www.readbyqxmd.com/read/28419819/path-to-illness-intrusiveness-what-symptoms-impact-the-life-of-people-living-with-multiple-sclerosis
#1
Vanessa Bouchard, Pierre Duquette, Nancy E Mayo
OBJECTIVE: To determine the direct and indirect effects of physical, emotional, and cognitive impairments on illness intrusiveness in people with MS. DESIGN: Secondary analysis of a cross sectional data set collected in 2008 to identify gender differences in people living with MS. SETTING: Three MS clinics in the Greater Montréal region, Canada. PARTICIPANTS: A random sample of 135 women and 48 men diagnosed with Multiple Sclerosis after 1995 recruited and evaluated in 2008...
April 15, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28295292/differential-neuronal-and-glial-expression-of-nuclear-factor-i-proteins-in-the-cerebral-cortex-of-adult-mice
#2
Kok-Siong Chen, Lachlan Harris, Jonathan W C Lim, Tracey J Harvey, Michael Piper, Richard M Gronostajski, Linda J Richards, Jens Bunt
The nuclear factor I (NFI) family of transcription factors plays an important role in the development of the cerebral cortex in humans and mice. Disruption of nuclear factor IA (NFIA), nuclear factor IB (NFIB), or nuclear factor IX (NFIX) results in abnormal development of the corpus callosum, lateral ventricles, and hippocampus. However, the expression or function of these genes has not been examined in detail in the adult brain, and the cell type-specific expression of NFIA, NFIB, and NFIX is currently unknown...
March 14, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28279394/validation-and-application-of-the-chinese-version-of-the-10-item-connor-davidson-resilience-scale-cd-risc-10-among-parents-of-children-with-cancer-diagnosis
#3
Zeng Jie Ye, Hong Zhong Qiu, Peng Fei Li, Peng Chen, Mu Zi Liang, Mei Ling Liu, Yuan Liang Yu, Shu Ni Wang, Xiao Ming Quan
PURPOSE: Parents of children diagnosed with cancer often experience considerable emotional distress for their children with negative emotions, such as disbelief, depression, anxiety, hope and shock. Resilience is defined as the psychological characteristics that promote positive adaptation in the face of stress and adversity, which has been demonstrated to relate to positive coping and less psychological distress. Thus, a quick screening tool to evaluate the levels of resilience of parents with cancer-diagnosed children is urgently required...
April 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/28273547/depression-and-resilience-mediates-the-effect-of-family-function-on-quality-of-life-of-the-elderly
#4
Canjie Lu, Lexin Yuan, Weiquan Lin, Ying Zhou, Shengmao Pan
BACKGROUND: Family function, which improves individual resilience and strongly link to quality of life (QOL) among the elderly, increases the risk of depression. Because of these demonstrated relationships, it can be hypothesized that both depression and resilience are mediators of the association between family function and QOL. METHODS: To test this hypothesis, the structural equation model (SEM) constructed by Amos 21.0 was employed to assess the indirect effect of depression (Geriatric Depression Scale, GDS) and resilience (Connor-Davidson Resilience Scale, CD-RISC) on the relationship between family function (Family APGAR Score, APGAR) and QOL (12-item Short Form health survey, SF-12) in 474 elderly adults from three communities in Guangzhou, China...
February 27, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28262660/reliability-and-validity-of-the-korean-version-of-the-cancer-stigma-scale
#5
Hyang Sook So, Myeong Jeong Chae, Hye Young Kim
PURPOSE: In this study the reliability and validity of the Korean version of the Cancer Stigma Scale (KCSS) was evaluated. METHODS: The KCSS was formed through translation and modification of Cataldo Lung Cancer Stigma Scale. The KCSS, Psychological Symptom Inventory (PSI), and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire - Core 30 (EORTC QLQ-C30) were administered to 247 men and women diagnosed with one of the five major cancers...
February 2017: Journal of Korean Academy of Nursing
https://www.readbyqxmd.com/read/28262655/-prediction-model-for-health-related-quality-of-life-in-hospitalized-patients-with-pulmonary-tuberculosis
#6
Kwang Sim Jang, Gyeong Suk Jeon
PURPOSE: This study was conducted to construct and test a structural equation model of health-related quality of life (HRQoL) among hospitalized patients with pulmonary tuberculosis (PTB). METHODS: Participants were 256 patients with PTB who were 20 years or older and admitted in two national tuberculosis hospitals. The patients participated in pulmonary function testing and responded to structured questionaries. RESULTS: The goodness-of-fit statistics of the final hypothetical model were as follows: χ²/df=2...
February 2017: Journal of Korean Academy of Nursing
https://www.readbyqxmd.com/read/28235731/carbon-dynamics-on-agricultural-land-reverting-to-woody-land-in-ontario-canada
#7
Mihai F Voicu, Cindy Shaw, Werner A Kurz, Ted Huffman, Jiangui Liu, Max Fellows
The 2015 Paris Agreement reinforces the importance of the land sector and its contribution to greenhouse gas (GHG) reductions. Thus, there is growing interest in improving estimates of the GHG balance in response to land-use changes (LUCs) involving agriculture and forestry, for national-scale reporting, and for carbon (C) offsets. Large agricultural areas in Europe, Russia and North America are reverting to forest, either naturally or through planting, after abandonment of agricultural land, and this trend may have a substantial impact on carbon budgets...
May 15, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28167668/myeloid-cell-specific-knockout-of-nfi-a-improves-sepsis-survival
#8
Melissa B McPeak, Dima Youssef, Danielle A Williams, Christopher Pritchett, Zhi Q Yao, Charles E McCall, Mohamed El Gazzar
Myeloid progenitor-derived suppressor cells (MDSCs) arise from myeloid progenitors and suppress both innate and adaptive immunity. MDSCs expand during the later phases of sepsis in mice, promote immunosuppression, and reduce survival. Here, we report that the myeloid differentiation-related transcription factor nuclear factor I-A (NFI-A) controls MDSC expansion during sepsis and impacts survival. Unlike MDSCs, myeloid cells with conditional deletion of the Nfia gene normally differentiated into effector cells during sepsis, cleared infecting bacteria, and did not express immunosuppressive mediators...
April 2017: Infection and Immunity
https://www.readbyqxmd.com/read/28165643/toward-inventory-based-estimates-of-soil-organic-carbon-in-forests-of-the-united-states
#9
G M Domke, C H Perry, B F Walters, L E Nave, C W Woodall, C W Swanston
Soil organic carbon (SOC) is the largest terrestrial carbon (C) sink on Earth; this pool plays a critical role in ecosystem processes and climate change. Given the cost and time required to measure SOC, and particularly changes in SOC, many signatory nations to the United Nations Framework Convention on Climate Change report estimates of SOC stocks and stock changes using default values from the Intergovernmental Panel on Climate Change or country-specific models. In the United States (US), SOC in forests is monitored by the national forest inventory (NFI) conducted by the Forest Inventory and Analysis (FIA) program within the US Department of Agriculture, Forest Service...
February 6, 2017: Ecological Applications: a Publication of the Ecological Society of America
https://www.readbyqxmd.com/read/28163183/a-femoral-common-vein-aneurysm-in-a-patient-with-neurofibromatosis-syndrome-type-1
#10
Christophe Seinturier, Sophie Blaise, Frédéric Thony, Jean Luc Magne, Gilles Pernod
Neurofibromatosis type I (NFI), also called Von Recklinghausen disease, is an autosomal dominant disease secondary to a genetic mutation on the long arm of chromosome 17. This disorder affects neural crest cells. Cutaneous clinical forms are the most frequent with multiple benign skin neurofibromas, associated with café au lait skin spots and iris hamartomas. Vascular abnormalities in NF1 are rare but have also been well described. The most frequent abnormalities are characterized by arterial aneurysm degeneration, stenosis, and malformations...
February 3, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28152469/cross-cultural-adaptation-and-psychometric-properties-of-the-korean-scale-for-internet-addiction-k-scale-in-japanese-high-school-students
#11
Kwok-Kei Mak, JeeEun Karin Nam, Dongil Kim, Narae Aum, Jung-Seok Choi, Cecilia Cheng, Huei-Chen Ko, Hiroko Watanabe
The Korean Scale for Internet Addiction (K-Scale) was developed in Korea for assessing addictive internet behaviors. This study aims to adopt K-Scale and examine its psychometric properties in Japanese adolescents. In 2014, 589 (36.0% boys) high school students (Grade 10-12) from Japan completed a survey, including items of Japanese versions of K-Scale and Smartphone Scale for Smartphone Addiction (S-Scale). Model fit indices of the original four-factor structure, three-factor structure obtained from exploratory factor analysis, and improved two-factor structure of K-Scale were computed using confirmatory factor analysis, with internal reliability of included items reported...
March 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28142298/palm-oil-and-human-health-meeting-report-of-nfi-nutrition-foundation-of-italy-symposium
#12
Franca Marangoni, Claudio Galli, Andrea Ghiselli, Giovanni Lercker, Carlo La Vecchia, Claudio Maffeis, Carlo Agostoni, Donatella Ballardini, Ovidio Brignoli, Pompilio Faggiano, Rosalba Giacco, Claudio Macca, Paolo Magni, Giuseppe Marelli, Walter Marrocco, Vito Leonardo Miniello, Gian Francesco Mureddu, Nicoletta Pellegrini, Roberto Stella, Ersilia Troiano, Elvira Verduci, Roberto Volpe, Andrea Poli
The use of palm oil by the food industry is increasingly criticized, especially in Italy, for its purported negative effects on human health and environment. This paper summarizes the conclusions of a Symposium on this topic, gathered by the Nutrition Foundation of Italy, among experts representing a number of Italian Medical and Nutritional Scientific Societies. Toxicological and environmental issues were not considered. Participants agreed that: no evidence does exist on the specific health effects of palm oil consumption as compared to other saturated fatty acids-rich fats; the stereospecific distribution of saturated fatty acids in the triacylglycerol molecule of palm oil limits their absorption rate and metabolic effects; in agreement with International guidelines, saturated fatty acids intake should be kept <10% of total energy, within a balanced diet; within these limits, no effect of palm oil consumption on human health (and specifically on CVD or cancer risk) can be foreseen...
January 31, 2017: International Journal of Food Sciences and Nutrition
https://www.readbyqxmd.com/read/28135037/anatomy-education-environment-measurement-inventory-a-valid-tool-to-measure-the-anatomy-learning-environment
#13
Siti Nurma Hanim Hadie, Asma' Hassan, Zul Izhar Mohd Ismail, Mohd Asnizam Asari, Aaijaz Ahmed Khan, Fazlina Kasim, Nurul Aiman Mohd Yusof, Husnaida Abdul Manan Sulong, Tg Fatimah Murniwati Tg Muda, Wan Nor Arifin, Muhamad Saiful Bahri Yusoff
Students' perceptions of the education environment influence their learning. Ever since the major medical curriculum reform, anatomy education has undergone several changes in terms of its curriculum, teaching modalities, learning resources, and assessment methods. By measuring students' perceptions concerning anatomy education environment, valuable information can be obtained to facilitate improvements in teaching and learning. Hence, it is important to use a valid inventory that specifically measures attributes of the anatomy education environment...
January 30, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/28101476/psychometric-properties-of-the-persian-version-of-the-quality-of-life-in-epilepsy-inventory-in-the-later-life
#14
Abdolrahim Asadollahi, Laleh Fani Saberi, Ali Havasi, Mohammad-Hossein Kaveh
BACKGROUND AND PURPOSE: The reports indicate on the incidence of seizure disorder about 1.5 per cent of the normal elderly population. The Quality of Life in Epilepsy Inventory (QOLIE-31) has been pervasive simple tool to screen seizure in the busy neurophysiological settings and monitoring. It was constructed as self-administered tool in two formats, 89 and 31-items. To the reliability and validity of the QOLIE-31 across older adults in the southwest Iran and discuss its role in the detection of health-related quality of elderly patients with epilepsy...
December 2016: Journal of Epilepsy Research
https://www.readbyqxmd.com/read/28077834/-validity-and-reliability-of-korean-version-of-the-spiritual-care-competence-scale
#15
Mi Ja Chung, Youngrye Park, Young Eun
PURPOSE: The aim of this study was to examine the validity and reliability of the Korean Version of the Spiritual Care Competence Scale (K-SCCS). METHODS: A cross-sectional study design was used. The K-SCCS consisted of 26 questions to measure spiritual care competence of nurses. Participants, 228 nurses who had more than 3 years'experience as a nurse, completed the survey. Confirmatory factor analysis was used to examine the construct validity and correlations of K-SCCS and spiritual well-being (SWB) were used to examine the criterion validity of K-SCCS...
December 2016: Journal of Korean Academy of Nursing
https://www.readbyqxmd.com/read/28076901/nuclear-factor-one-transcription-factors-as-epigenetic-regulators-in-cancer
#16
REVIEW
Mitchell Fane, Lachlan Harris, Aaron G Smith, Michael Piper
Tumour heterogeneity poses a distinct obstacle to therapeutic intervention. While the initiation of tumours across various physiological systems is frequently associated with signature mutations in genes that drive proliferation and bypass senescence, increasing evidence suggests that tumour progression and clonal diversity is driven at an epigenetic level. The tumour microenvironment plays a key role in driving diversity as cells adapt to demands during tumour growth, and is thought to drive certain subpopulations back to a stem cell-like state...
January 11, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28041969/needle-free-injection-of-vesicular-phospholipid-gels-a-novel-approach-to-overcome-an-administration-hurdle-for-semisolid-depot-systems
#17
Michaela Breitsamer, Gerhard Winter
Vesicular phospholipid gels (VPGs) are depot formulations for the sustained release of drugs which are characterized by a high amount of phospholipids in the formulation. They consist of physiological excipients only and therefore display high biocompatibility. Their manufacture is simple, cheap, solvent free, and ideal for the processing of proteins and peptides because of the low stress on the molecule, for example, by elevated temperatures. One major hurdle of VPGs is their high viscosity which makes them hard to almost impossible to inject with conventional, thin needles used for subcutaneous administration...
December 29, 2016: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28011440/adaptation-to-nursing-home-the-role-of-leisure-activities-in-light-of-motivation-and-relatedness
#18
Emin Altintas, Giorgio De Benedetto, Karim Gallouj
Based on the motivational sequence described in Self-Determination Theory, this study explored the relationship between relatedness, motivation, adaptation and leisure in nursing homes. We formulated the hypothesis that the variables of the study would be found in an integrative mediational sequence: Participation in leisure activities→Relatedness→Self-determined motivation→Adaptation to nursing homes. Participants (N=112, mean age=84.17) were invited to complete questionnaires assessing these variables...
May 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27984242/impact-of-abuse-on-adjustment-and-chronic-pain-disability-a-structural-equation-model
#19
Swati Mehta, Danielle Rice, Alan Chan, Allan P Shapiro, Keith Sequeira, Robert W Teasell
INTRODUCTION/AIM: Sexual abuse, "state" and "trait" psychosocial factors, pain intensity, and pain related disability have been shown to be correlated among individuals with chronic pain. However, the interacting relationships between these factors is poorly understood. The current study aims to test model which examines the effect of abuse, "state" and "trait" psychosocial factors, and pain intensity on pain related disability among individuals with chronic pain. METHODS: 229 participants diagnosed with chronic pain were recruited from a specialist chronic pain hospital in London, Ontario...
December 15, 2016: Clinical Journal of Pain
https://www.readbyqxmd.com/read/27965439/transcriptional-regulation-of-intermediate-progenitor-cell-generation-during-hippocampal-development
#20
Lachlan Harris, Oressia Zalucki, Ilan Gobius, Hannah McDonald, Jason Osinki, Tracey J Harvey, Alexandra Essebier, Diana Vidovic, Ivan Gladwyn-Ng, Thomas H Burne, Julian I Heng, Linda J Richards, Richard M Gronostajski, Michael Piper
During forebrain development, radial glia generate neurons through the production of intermediate progenitor cells (IPCs). The production of IPCs is a central tenet underlying the generation of the appropriate number of cortical neurons, but the transcriptional logic underpinning this process remains poorly defined. Here, we examined IPC production using mice lacking the transcription factor nuclear factor I/X (Nfix). We show that Nfix deficiency delays IPC production and prolongs the neurogenic window, resulting in an increased number of neurons in the postnatal forebrain...
December 15, 2016: Development
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