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https://www.readbyqxmd.com/read/28641771/fatigue-in-multiple-sclerosis-is-it-related-to-cytokines-and-hypothalamic-pituitary-adrenal-axis
#1
Aylin Akcali, Fatma Zengin, Sefika Nur Aksoy, Orhan Zengin
BACKGROUND: Fatigue is a common symptom of Multiple Sclerosis (MS) that diminishes the quality of life of patients, but its exact mechanism remains poorly understood. There is not a generally adopted scale to determine MS fatigue. Studies that investigated physiopathology of fatigue symptom have shown dysregulation of hypothalamic-pituitaryadrenal (HPA) axis. In the current study, we aimed to compare the results obtained with two separate scales, namely the Fatigue Severity Scale (FSS) and the Neurological Fatigue Index-Multiple Sclerosis (NFI-MS), and assess the relationship between fatigue and serum IL-1β, TNF-α, IL-35, IL-2, IL-10, ACTH, cortisol, α-MSH, β-MSH, γ-MSH and CLIP (Corticotropinlike intermediate lobe peptide) in MS patients categorized as fatigued and non-fatigued on the basis of FSS scores...
July 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/28636163/the-pu-prom-a-patient-reported-outcome-measure-for-peptic-ulcer-disease
#2
Na Liu, Jing Lv, Jinchun Liu, Yanbo Zhang
OBJECTIVE: Patient-reported outcome measure (PROM) conceived to enable description of treatment-related effects, from the patient perspective, bring the potential to improve in clinical research, and to provide patients with accurate information. Therefore, the aim of this study was to develop a patient-centred peptic ulcer patient-reported outcome measure (PU-PROM) and evaluate its reliability, validity, differential item functioning (DIF) and feasibility. METHOD: To develop a conceptual framework and item pool for the PU-PROM, we performed a literature review and consulted other measures created in China and other countries...
June 21, 2017: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/28612931/a-rating-scale-for-the-severity-of-guillain-barr%C3%A3-syndrome
#3
Z Guan, L Shang, W Zhang, Y Guo, Y Xue, X Li, Y Gong, X Liu
INTRODUCTION: The objective of this study was to develop a rating scale to assess the severity of Guillain-Barré syndrome (GBS). METHODS: The preliminary rating scale, which contained 11 items, was developed by the Delphi method, and data of 258 patients were collected to evaluate it. Item analysis was accomplished by 100 patients; the additional 158 patients were used to evaluate the reliability, validity, and discriminative ability of the rating scale. The structure of the rating scale was testified by the confirmatory factor analysis and also made a further evaluation by the correlation analysis...
June 14, 2017: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/28545471/decisional-balance-inventory-dbi-adolescent-form-for-smoking-psychometric-properties-of-the-persian-version
#4
Maryam Khazaee-Pool, Tahereh Pashaei, Ponnet Koen, Fatemeh Jafari, Rashin Alizadeh
BACKGROUND: One effective model for studying cigarette smoking cessation is the transtheoretical model (TTM). In order to assess to what degree interventions can make variations in individuals' behavior, several questionnaires have been developed based on the TTM. This study aims to describe the development of the Persian version of the Decisional Balance Inventory (DBI) for smoking cessation in Iran and to evaluate its psychometric properties. DESIGN AND METHODS: The forward-backward technique was used to translate the DBI from English into Persian...
May 25, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28510288/the-relationship-of-physiopsychosocial-factors-and-spiritual-well-being-in-elderly-residents-implications-for-evidence-based-practice
#5
Yi-Heng Chen, Li-Chan Lin, Li-Lan Chuang, Mei-Li Chen
BACKGROUND: Older adults in residential settings frequently suffer from functional decline, mental illness, and social isolation, which make them more vulnerable to spiritual distress. However, empirical evidence of the interrelationships between physiopsychosocial variables and spiritual well-being are still lacking, limiting the application of the biopsychosocial-spiritual model in institutional healthcare practice. AIMS: To explain the mechanisms by which these variables are linked, this cross-sectional study tested a causal model of predictors of spiritual well-being among 377 institutionalized older adults with disability using a structural equation modeling approach...
May 16, 2017: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/28492955/the-association-of-self-concept-with-substance-abuse-and-problematic-use-of-video-games-in-university-students-a-structural-equation-model
#6
Ramón Chacón Cuberos, Félix Zurita Ortega, Manuel Castro Sánchez, Tamara Espejo Garcés, Asunción Martínez Martínez, Gerardo Ruiz-Rico Ruiz
This study aims to define and contrast an explanatory model of consumption of alcohol, tobacco consumption, and problematic use of video games based on self-concept and its dimensions in a sample of university students. The research was conducted with a sample of 490 students from the province of Granada (Spain), aged between 20 and 29 years (M = 22.80 ± 3.63), with a homogeneous distribution by gender. The instruments used were the Self-concept Form-5 Questionnaire (García & Musitu, 1999), the Alcohol Use Disorders Identification Test (Saunders, Aasland, Babor, De la Fuente, & Grant, 1993), the Fagerström Test for Nicotine Dependence (Heatherton, Kozlowski, Frecker, & Fagerström, 1991) and the Questionnaire for Experiences Related to Video Games (Chamarro et al...
April 12, 2017: Adicciones
https://www.readbyqxmd.com/read/28470158/-structural-equation-modeling-on-smoking-cessation-intention-in-male-technical-high-school-students
#7
Eun Su Do, Eunsuk Choi
PURPOSE: This study was done to develop and test a structural model on smoking cessation intention in technical high school men. The conceptual model was based on the theory of reasoned action and health promotion model. METHODS: From May 29 to April 13, 2015, 413 technical high school students who smoked completed a structured questionnaire. Data were analyzed to calculate the direct and indirect effects of factors affecting smoking cessation intention. The SPSS WIN 20...
April 2017: Journal of Korean Academy of Nursing
https://www.readbyqxmd.com/read/28464884/risk-factors-for-postpartum-depression-among-chinese-women-path-model-analysis
#8
Shiping Liu, Yan Yan, Xiao Gao, Shiting Xiang, Tingting Sha, Guangyu Zeng, Qiong He
BACKGROUND: Postpartum depression causes harm to both mothers and infants. The purpose of this study was to find out several potential risk factors, and to identify the intrinsic interrelationships between factors and postpartum depression by constructing a path model. The results of this study may help to control the increasing incidence of maternal postpartum depression. METHODS: The study was based on a sample of mothers from a cross-sectional study which was set up at 4 weeks after a mother had childbirth and was conducted in three streets at Kaifu District of Changsha in Hunan province from January to December 2015...
May 2, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28462188/the-role-of-nuclear-factor-i-c-in-tooth-and-bone-development
#9
REVIEW
Song Yi Roh, Joo-Cheol Park
Nuclear factor I-C (NFI-C) plays a pivotal role in various cellular processes such as odontoblast and osteoblast differentiation. Nfic-deficient mice showed abnormal tooth and bone formation. The transplantation of Nfic-expressing mouse bone marrow stromal cells rescued the impaired bone formation in Nfic(-/-) mice. Studies suggest that NFI-C regulate osteogenesis and dentinogenesis in concert with several factors including transforming growth factor-β1, Krüppel-like factor 4, and β-catenin. This review will focus on the function of NFI-C during tooth and bone formation and on the relevant pathways that involve NFI-C...
April 2017: Journal of the Korean Association of Oral and Maxillofacial Surgeons
https://www.readbyqxmd.com/read/28454627/implementation-and-assessment-of-a-likelihood-ratio-approach-for-the-evaluation-of-la-icp-ms-evidence-in-forensic-glass-analysis
#10
Andrew van Es, Wim Wiarda, Maarten Hordijk, Ivo Alberink, Peter Vergeer
For the comparative analysis of glass fragments, a method using Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) is in use at the NFI, giving measurements of the concentration of 18 elements. An important question is how to evaluate the results as evidence that a glass sample originates from a known glass source or from an arbitrary different glass source. One approach is the use of matching criteria e.g. based on a t-test or overlap of confidence intervals. An important drawback of this method is the fact that the rarity of the glass composition is not taken into account...
May 2017: Science & Justice: Journal of the Forensic Science Society
https://www.readbyqxmd.com/read/28447176/the-structural-model-of-spirituality-and-psychological-well-being-for-pregnancy-specific-stress
#11
Mahrokh Dolatian, Zohreh Mahmoodi, Taibeh Dilgony, Jamal Shams, Farid Zaeri
Women experience different types of stress in their lifetime. The present study was conducted to examine the structural model of spirituality and psychological well-being for pregnancy-specific stress. The present descriptive correlational study was conducted on 450 pregnant Iranian women (150 women from each trimester) in Dehdasht city in 2015. Data were collected using the personal-social questionnaire, the pregnancy-specific stress questionnaire, the spirituality questionnaire and the psychological well-being questionnaire and were then analyzed in SPSS-16 and Lisrel-8...
April 26, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28419819/path-to-illness-intrusiveness-what-symptoms-impact-the-life-of-people-living-with-multiple-sclerosis
#12
Vanessa Bouchard, Pierre Duquette, Nancy E Mayo
OBJECTIVE: To determine the direct and indirect effects of physical, emotional, and cognitive impairments on illness intrusiveness in people with MS. DESIGN: Secondary analysis of a cross sectional data set collected in 2008 to identify gender differences in people living with MS. SETTING: Three MS clinics in the Greater Montréal region, Canada. PARTICIPANTS: A random sample of 135 women and 48 men diagnosed with Multiple Sclerosis after 1995 recruited and evaluated in 2008...
April 15, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28295292/differential-neuronal-and-glial-expression-of-nuclear-factor-i-proteins-in-the-cerebral-cortex-of-adult-mice
#13
Kok-Siong Chen, Lachlan Harris, Jonathan W C Lim, Tracey J Harvey, Michael Piper, Richard M Gronostajski, Linda J Richards, Jens Bunt
The nuclear factor I (NFI) family of transcription factors plays an important role in the development of the cerebral cortex in humans and mice. Disruption of nuclear factor IA (NFIA), nuclear factor IB (NFIB), or nuclear factor IX (NFIX) results in abnormal development of the corpus callosum, lateral ventricles, and hippocampus. However, the expression or function of these genes has not been examined in detail in the adult brain, and the cell type-specific expression of NFIA, NFIB, and NFIX is currently unknown...
August 1, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28279394/validation-and-application-of-the-chinese-version-of-the-10-item-connor-davidson-resilience-scale-cd-risc-10-among-parents-of-children-with-cancer-diagnosis
#14
Zeng Jie Ye, Hong Zhong Qiu, Peng Fei Li, Peng Chen, Mu Zi Liang, Mei Ling Liu, Yuan Liang Yu, Shu Ni Wang, Xiao Ming Quan
PURPOSE: Parents of children diagnosed with cancer often experience considerable emotional distress for their children with negative emotions, such as disbelief, depression, anxiety, hope and shock. Resilience is defined as the psychological characteristics that promote positive adaptation in the face of stress and adversity, which has been demonstrated to relate to positive coping and less psychological distress. Thus, a quick screening tool to evaluate the levels of resilience of parents with cancer-diagnosed children is urgently required...
April 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/28273547/depression-and-resilience-mediates-the-effect-of-family-function-on-quality-of-life-of-the-elderly
#15
Canjie Lu, Lexin Yuan, Weiquan Lin, Ying Zhou, Shengmao Pan
BACKGROUND: Family function, which improves individual resilience and strongly link to quality of life (QOL) among the elderly, increases the risk of depression. Because of these demonstrated relationships, it can be hypothesized that both depression and resilience are mediators of the association between family function and QOL. METHODS: To test this hypothesis, the structural equation model (SEM) constructed by Amos 21.0 was employed to assess the indirect effect of depression (Geriatric Depression Scale, GDS) and resilience (Connor-Davidson Resilience Scale, CD-RISC) on the relationship between family function (Family APGAR Score, APGAR) and QOL (12-item Short Form health survey, SF-12) in 474 elderly adults from three communities in Guangzhou, China...
July 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28262660/reliability-and-validity-of-the-korean-version-of-the-cancer-stigma-scale
#16
Hyang Sook So, Myeong Jeong Chae, Hye Young Kim
PURPOSE: In this study the reliability and validity of the Korean version of the Cancer Stigma Scale (KCSS) was evaluated. METHODS: The KCSS was formed through translation and modification of Cataldo Lung Cancer Stigma Scale. The KCSS, Psychological Symptom Inventory (PSI), and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire - Core 30 (EORTC QLQ-C30) were administered to 247 men and women diagnosed with one of the five major cancers...
February 2017: Journal of Korean Academy of Nursing
https://www.readbyqxmd.com/read/28262655/-prediction-model-for-health-related-quality-of-life-in-hospitalized-patients-with-pulmonary-tuberculosis
#17
Kwang Sim Jang, Gyeong Suk Jeon
PURPOSE: This study was conducted to construct and test a structural equation model of health-related quality of life (HRQoL) among hospitalized patients with pulmonary tuberculosis (PTB). METHODS: Participants were 256 patients with PTB who were 20 years or older and admitted in two national tuberculosis hospitals. The patients participated in pulmonary function testing and responded to structured questionaries. RESULTS: The goodness-of-fit statistics of the final hypothetical model were as follows: χ²/df=2...
February 2017: Journal of Korean Academy of Nursing
https://www.readbyqxmd.com/read/28235731/carbon-dynamics-on-agricultural-land-reverting-to-woody-land-in-ontario-canada
#18
Mihai F Voicu, Cindy Shaw, Werner A Kurz, Ted Huffman, Jiangui Liu, Max Fellows
The 2015 Paris Agreement reinforces the importance of the land sector and its contribution to greenhouse gas (GHG) reductions. Thus, there is growing interest in improving estimates of the GHG balance in response to land-use changes (LUCs) involving agriculture and forestry, for national-scale reporting, and for carbon (C) offsets. Large agricultural areas in Europe, Russia and North America are reverting to forest, either naturally or through planting, after abandonment of agricultural land, and this trend may have a substantial impact on carbon budgets...
May 15, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28167668/myeloid-cell-specific-knockout-of-nfi-a-improves-sepsis-survival
#19
Melissa B McPeak, Dima Youssef, Danielle A Williams, Christopher Pritchett, Zhi Q Yao, Charles E McCall, Mohamed El Gazzar
Myeloid progenitor-derived suppressor cells (MDSCs) arise from myeloid progenitors and suppress both innate and adaptive immunity. MDSCs expand during the later phases of sepsis in mice, promote immunosuppression, and reduce survival. Here, we report that the myeloid differentiation-related transcription factor nuclear factor I-A (NFI-A) controls MDSC expansion during sepsis and impacts survival. Unlike MDSCs, myeloid cells with conditional deletion of the Nfia gene normally differentiated into effector cells during sepsis, cleared infecting bacteria, and did not express immunosuppressive mediators...
April 2017: Infection and Immunity
https://www.readbyqxmd.com/read/28165643/toward-inventory-based-estimates-of-soil-organic-carbon-in-forests-of-the-united-states
#20
G M Domke, C H Perry, B F Walters, L E Nave, C W Woodall, C W Swanston
Soil organic carbon (SOC) is the largest terrestrial carbon (C) sink on Earth; this pool plays a critical role in ecosystem processes and climate change. Given the cost and time required to measure SOC, and particularly changes in SOC, many signatory nations to the United Nations Framework Convention on Climate Change report estimates of SOC stocks and stock changes using default values from the Intergovernmental Panel on Climate Change or country-specific models. In the United States, SOC in forests is monitored by the national forest inventory (NFI) conducted by the Forest Inventory and Analysis (FIA) program within the U...
February 6, 2017: Ecological Applications: a Publication of the Ecological Society of America
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