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https://www.readbyqxmd.com/read/28727836/the-disc-damage-likelihood-scale-diagnostic-accuracy-and-correlations-with-cup-to-disc-ratio-structural-tests-and-standard-automated-perimetry
#1
Andrea C Kara-José, Luiz Alberto S Melo, Bruno L B Esporcatte, Angelica T N H Endo, Mauro Toledo Leite, Ivan Maynart Tavares
Our objective was to compare the diagnostic accuracies of and to determine the correlations between the disc damage likelihood scale (DDLS) and anatomical and functional tests used for glaucoma detection. A total of 54 healthy subjects (54 eyes) and 47 primary open-angle glaucoma patients (47 eyes) were included in this cross-sectional observational study. DDLS scores and cup-to-disc (C/D) ratios were evaluated. Subjects underwent standard automated perimetry (SAP), optic disc and retinal nerve fiber layer (RNFL) imaging with time and spectral-domain optical coherence tomography (TD and SD-OCT), Heidelberg Retina Tomograph (HRT II), and scanning laser polarimetry (GDx-VCC)...
2017: PloS One
https://www.readbyqxmd.com/read/28718867/-defeated-by-life-validation-of-a-german-version-of-the-defeat-scale-ds-d
#2
Thomas Forkmann, Jana-Sophie Stenzel, Dajana Rath, Heide Glaesmer, Tobias Teismann
Introduction Defeat and entrapment are transdiagnostic constructs that play an important role in the development of depression, anxiety, suicidality and trauma-associated mental disorders. The present study aimed at presenting and validating a first German version of the Defeat-Scale (DS-d). Material and methods Through a web-based survey, N=480 participants were recruited (74% female; MAge=28.5, SDAge=11.1, Range: 18-80 years); 14.2% reported to currently suffer from a mental disorder, 8.5% reported at least one lifetime suicide attempt...
June 29, 2017: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/28706282/retinal-degeneration-in-progressive-supranuclear-palsy-measured-by-optical-coherence-tomography-and-scanning-laser-polarimetry
#3
Birthe Stemplewitz, Robert Kromer, Eik Vettorazzi, Ute Hidding, Andreas Frings, Carsten Buhmann
This cross-sectional study compared the retinal morphology between patients with progressive supranuclear palsy (PSP) and healthy controls. (The retinal nerve fiber layer (RNFL) around the optic disc and the retina in the macular area of 22 PSP patients and 151 controls were investigated by spectral domain optical coherence tomography (SD-OCT). Additionally, the RNFL and the nerve fiber index (NFI) were measured by scanning laser polarimetry (SLP). Results of RNFL measurements with SD-OCT and SLP were compared to assess diagnostic discriminatory power...
July 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28662855/measuring-physical-and-cognitive-fatigue-in-people-with-post-polio-syndrome-development-of-the-neurological-fatigue-index-for-post-polio-syndrome-nfi-pp
#4
Carolyn A Young, Samantha M Wong, Anne-Marie C Quincey, Alan Tennant
BACKGROUND: Fatigue in post-polio syndrome (PPS) has been shown to affect quality of life adversely. There is currently no disease-specific measure of fatigue for PPS. OBJECTIVE: To develop a scale to measure fatigue in PPS that meets rigorous psychometric standards. DESIGN: Qualitative followed by validation and test-retest studies. SETTING: Polio clinic followed by national questionnaire studies. PARTICIPANTS: A total of 45 participants from polio clinic for qualitative; 319 participants from clinic or self-referral for validation study, of whom 110 completed the retest questionnaire...
June 27, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28658822/recurrent-optic-nerve-pilocytic-astrocytoma-a-rare-case
#5
Sudha Girish Menon, Vuppalapati Nishant Janardhana Raju, Sulatha V Bhandary, Krishna Rao Addoor
Pilocytic astrocytoma is a low grade glioma that affects mostly children and young adults and can occur anywhere in the central nervous system. Pilocytic astrocytoma of the optic nerve is an equally indolent subtype that is often associated with Neurofibromatosis Type I (NFI). A 40-year-old male presented with left sided axial proptosis and exposure keratopathy. MRI revealed a mass in left proximal orbit, extending posteriorly abutting the chiasma and the right optic nerve on MRI. Enucleation of the left eye along with near total excision of intracranial part of the mass was performed...
May 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28652701/follow-up-of-the-retinal-nerve-fiber-layer-thickness-of-diabetic-patients-type-2-as-a-predisposing-factor-for-glaucoma-compared-to-normal-subjects
#6
Alexandros Takis, Dimitrios Alonistiotis, Nikolaos Ioannou, Evgenia Kontou, Maria Mitsopoulou, Dimitrios Papaconstantinou
PURPOSE: To evaluate and follow-up the retinal nerve fiber layer (RNFL) thickness in patients with diabetes mellitus type 2 compared to a group of healthy individuals with similar demographic characteristics. PATIENTS AND METHODS: This is a prospective, noninvasive, observational case series study. For the purposes of the study, 27 eyes of diabetic patients without diabetic retinopathy, 24 eyes of patients with mild retinopathy, and 25 normal age-matched subjects (control group [CG]) were examined...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28641771/fatigue-in-multiple-sclerosis-is-it-related-to-cytokines-and-hypothalamic-pituitary-adrenal-axis
#7
Aylin Akcali, Fatma Zengin, Sefika Nur Aksoy, Orhan Zengin
BACKGROUND: Fatigue is a common symptom of Multiple Sclerosis (MS) that diminishes the quality of life of patients, but its exact mechanism remains poorly understood. There is not a generally adopted scale to determine MS fatigue. Studies that investigated physiopathology of fatigue symptom have shown dysregulation of hypothalamic-pituitaryadrenal (HPA) axis. In the current study, we aimed to compare the results obtained with two separate scales, namely the Fatigue Severity Scale (FSS) and the Neurological Fatigue Index-Multiple Sclerosis (NFI-MS), and assess the relationship between fatigue and serum IL-1β, TNF-α, IL-35, IL-2, IL-10, ACTH, cortisol, α-MSH, β-MSH, γ-MSH and CLIP (Corticotropinlike intermediate lobe peptide) in MS patients categorized as fatigued and non-fatigued on the basis of FSS scores...
July 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/28636163/the-pu-prom-a-patient-reported-outcome-measure-for-peptic-ulcer-disease
#8
Na Liu, Jing Lv, Jinchun Liu, Yanbo Zhang
OBJECTIVE: Patient-reported outcome measure (PROM) conceived to enable description of treatment-related effects, from the patient perspective, bring the potential to improve in clinical research, and to provide patients with accurate information. Therefore, the aim of this study was to develop a patient-centred peptic ulcer patient-reported outcome measure (PU-PROM) and evaluate its reliability, validity, differential item functioning (DIF) and feasibility. METHOD: To develop a conceptual framework and item pool for the PU-PROM, we performed a literature review and consulted other measures created in China and other countries...
June 21, 2017: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/28612931/a-rating-scale-for-the-severity-of-guillain-barr%C3%A3-syndrome
#9
Z Guan, L Shang, W Zhang, Y Guo, Y Xue, X Li, Y Gong, X Liu
INTRODUCTION: The objective of this study was to develop a rating scale to assess the severity of Guillain-Barré syndrome (GBS). METHODS: The preliminary rating scale, which contained 11 items, was developed by the Delphi method, and data of 258 patients were collected to evaluate it. Item analysis was accomplished by 100 patients; the additional 158 patients were used to evaluate the reliability, validity, and discriminative ability of the rating scale. The structure of the rating scale was testified by the confirmatory factor analysis and also made a further evaluation by the correlation analysis...
June 14, 2017: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/28545471/decisional-balance-inventory-dbi-adolescent-form-for-smoking-psychometric-properties-of-the-persian-version
#10
Maryam Khazaee-Pool, Tahereh Pashaei, Ponnet Koen, Fatemeh Jafari, Rashin Alizadeh
BACKGROUND: One effective model for studying cigarette smoking cessation is the transtheoretical model (TTM). In order to assess to what degree interventions can make variations in individuals' behavior, several questionnaires have been developed based on the TTM. This study aims to describe the development of the Persian version of the Decisional Balance Inventory (DBI) for smoking cessation in Iran and to evaluate its psychometric properties. DESIGN AND METHODS: The forward-backward technique was used to translate the DBI from English into Persian...
May 25, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28510288/the-relationship-of-physiopsychosocial-factors-and-spiritual-well-being-in-elderly-residents-implications-for-evidence-based-practice
#11
Yi-Heng Chen, Li-Chan Lin, Li-Lan Chuang, Mei-Li Chen
BACKGROUND: Older adults in residential settings frequently suffer from functional decline, mental illness, and social isolation, which make them more vulnerable to spiritual distress. However, empirical evidence of the interrelationships between physiopsychosocial variables and spiritual well-being are still lacking, limiting the application of the biopsychosocial-spiritual model in institutional healthcare practice. AIMS: To explain the mechanisms by which these variables are linked, this cross-sectional study tested a causal model of predictors of spiritual well-being among 377 institutionalized older adults with disability using a structural equation modeling approach...
May 16, 2017: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/28492955/the-association-of-self-concept-with-substance-abuse-and-problematic-use-of-video-games-in-university-students-a-structural-equation-model
#12
Ramón Chacón Cuberos, Félix Zurita Ortega, Manuel Castro Sánchez, Tamara Espejo Garcés, Asunción Martínez Martínez, Gerardo Ruiz-Rico Ruiz
This study aims to define and contrast an explanatory model of consumption of alcohol, tobacco consumption, and problematic use of video games based on self-concept and its dimensions in a sample of university students. The research was conducted with a sample of 490 students from the province of Granada (Spain), aged between 20 and 29 years (M = 22.80 ± 3.63), with a homogeneous distribution by gender. The instruments used were the Self-concept Form-5 Questionnaire (García & Musitu, 1999), the Alcohol Use Disorders Identification Test (Saunders, Aasland, Babor, De la Fuente, & Grant, 1993), the Fagerström Test for Nicotine Dependence (Heatherton, Kozlowski, Frecker, & Fagerström, 1991) and the Questionnaire for Experiences Related to Video Games (Chamarro et al...
April 12, 2017: Adicciones
https://www.readbyqxmd.com/read/28470158/-structural-equation-modeling-on-smoking-cessation-intention-in-male-technical-high-school-students
#13
Eun Su Do, Eunsuk Choi
PURPOSE: This study was done to develop and test a structural model on smoking cessation intention in technical high school men. The conceptual model was based on the theory of reasoned action and health promotion model. METHODS: From May 29 to April 13, 2015, 413 technical high school students who smoked completed a structured questionnaire. Data were analyzed to calculate the direct and indirect effects of factors affecting smoking cessation intention. The SPSS WIN 20...
April 2017: Journal of Korean Academy of Nursing
https://www.readbyqxmd.com/read/28464884/risk-factors-for-postpartum-depression-among-chinese-women-path-model-analysis
#14
Shiping Liu, Yan Yan, Xiao Gao, Shiting Xiang, Tingting Sha, Guangyu Zeng, Qiong He
BACKGROUND: Postpartum depression causes harm to both mothers and infants. The purpose of this study was to find out several potential risk factors, and to identify the intrinsic interrelationships between factors and postpartum depression by constructing a path model. The results of this study may help to control the increasing incidence of maternal postpartum depression. METHODS: The study was based on a sample of mothers from a cross-sectional study which was set up at 4 weeks after a mother had childbirth and was conducted in three streets at Kaifu District of Changsha in Hunan province from January to December 2015...
May 2, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28462188/the-role-of-nuclear-factor-i-c-in-tooth-and-bone-development
#15
REVIEW
Song Yi Roh, Joo-Cheol Park
Nuclear factor I-C (NFI-C) plays a pivotal role in various cellular processes such as odontoblast and osteoblast differentiation. Nfic-deficient mice showed abnormal tooth and bone formation. The transplantation of Nfic-expressing mouse bone marrow stromal cells rescued the impaired bone formation in Nfic(-/-) mice. Studies suggest that NFI-C regulate osteogenesis and dentinogenesis in concert with several factors including transforming growth factor-β1, Krüppel-like factor 4, and β-catenin. This review will focus on the function of NFI-C during tooth and bone formation and on the relevant pathways that involve NFI-C...
April 2017: Journal of the Korean Association of Oral and Maxillofacial Surgeons
https://www.readbyqxmd.com/read/28454627/implementation-and-assessment-of-a-likelihood-ratio-approach-for-the-evaluation-of-la-icp-ms-evidence-in-forensic-glass-analysis
#16
Andrew van Es, Wim Wiarda, Maarten Hordijk, Ivo Alberink, Peter Vergeer
For the comparative analysis of glass fragments, a method using Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) is in use at the NFI, giving measurements of the concentration of 18 elements. An important question is how to evaluate the results as evidence that a glass sample originates from a known glass source or from an arbitrary different glass source. One approach is the use of matching criteria e.g. based on a t-test or overlap of confidence intervals. An important drawback of this method is the fact that the rarity of the glass composition is not taken into account...
May 2017: Science & Justice: Journal of the Forensic Science Society
https://www.readbyqxmd.com/read/28447176/the-structural-model-of-spirituality-and-psychological-well-being-for-pregnancy-specific-stress
#17
Mahrokh Dolatian, Zohreh Mahmoodi, Taibeh Dilgony, Jamal Shams, Farid Zaeri
Women experience different types of stress in their lifetime. The present study was conducted to examine the structural model of spirituality and psychological well-being for pregnancy-specific stress. The present descriptive correlational study was conducted on 450 pregnant Iranian women (150 women from each trimester) in Dehdasht city in 2015. Data were collected using the personal-social questionnaire, the pregnancy-specific stress questionnaire, the spirituality questionnaire and the psychological well-being questionnaire and were then analyzed in SPSS-16 and Lisrel-8...
April 26, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28419819/path-to-illness-intrusiveness-what-symptoms-impact-the-life-of-people-living-with-multiple-sclerosis
#18
Vanessa Bouchard, Pierre Duquette, Nancy E Mayo
OBJECTIVE: To determine the direct and indirect effects of physical, emotional, and cognitive impairments on illness intrusiveness in people with MS. DESIGN: Secondary analysis of a cross sectional data set collected in 2008 to identify gender differences in people living with MS. SETTING: Three MS clinics in the Greater Montréal region, Canada. PARTICIPANTS: A random sample of 135 women and 48 men diagnosed with Multiple Sclerosis after 1995 recruited and evaluated in 2008...
April 15, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28295292/differential-neuronal-and-glial-expression-of-nuclear-factor-i-proteins-in-the-cerebral-cortex-of-adult-mice
#19
Kok-Siong Chen, Lachlan Harris, Jonathan W C Lim, Tracey J Harvey, Michael Piper, Richard M Gronostajski, Linda J Richards, Jens Bunt
The nuclear factor I (NFI) family of transcription factors plays an important role in the development of the cerebral cortex in humans and mice. Disruption of nuclear factor IA (NFIA), nuclear factor IB (NFIB), or nuclear factor IX (NFIX) results in abnormal development of the corpus callosum, lateral ventricles, and hippocampus. However, the expression or function of these genes has not been examined in detail in the adult brain, and the cell type-specific expression of NFIA, NFIB, and NFIX is currently unknown...
August 1, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28279394/validation-and-application-of-the-chinese-version-of-the-10-item-connor-davidson-resilience-scale-cd-risc-10-among-parents-of-children-with-cancer-diagnosis
#20
Zeng Jie Ye, Hong Zhong Qiu, Peng Fei Li, Peng Chen, Mu Zi Liang, Mei Ling Liu, Yuan Liang Yu, Shu Ni Wang, Xiao Ming Quan
PURPOSE: Parents of children diagnosed with cancer often experience considerable emotional distress for their children with negative emotions, such as disbelief, depression, anxiety, hope and shock. Resilience is defined as the psychological characteristics that promote positive adaptation in the face of stress and adversity, which has been demonstrated to relate to positive coping and less psychological distress. Thus, a quick screening tool to evaluate the levels of resilience of parents with cancer-diagnosed children is urgently required...
April 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
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