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https://www.readbyqxmd.com/read/29245124/bisphenol-and-phthalate-concentrations-and-its-determinants-among-pregnant-women-in-a-population-based-cohort-in-the-netherlands-2004-5
#1
Elise M Philips, Vincent W V Jaddoe, Alexandros G Asimakopoulos, Kurunthachalam Kannan, Eric A P Steegers, Susana Santos, Leonardo Trasande
BACKGROUND: Exposure to bisphenols and phthalates in pregnancy may lead to adverse health effects in women themselves and their offspring. OBJECTIVE: To describe first trimester bisphenol and phthalate urine concentrations, including bisphenol and phthalate replacements, and determine nutritional, socio-demographic and lifestyle related determinants. METHODS: In a population-based prospective cohort of 1396 mothers, we measured first trimester bisphenol, phthalate and creatinine urine concentrations (samples collected in 2004-2005, median gestational age 12...
December 12, 2017: Environmental Research
https://www.readbyqxmd.com/read/29244813/a-different-view-on-the-necker-cube-differences-in-multistable-perception-dynamics-between-asperger-and-non-asperger-observers
#2
Jürgen Kornmeier, Rike Wörner, Andreas Riedel, Ludger Tebartz van Elst
BACKGROUND: During observation of the Necker cube perception becomes unstable and alternates repeatedly between a from-above-perspective ("fap") and a from-below-perspective ("fbp") interpretation. Both interpretations are physically equally plausible, however, observers usually show an a priori top-down bias in favor of the fap interpretation. Patients with Autism spectrum disorder are known to show an altered pattern of perception with a focus on sensory details. In the present study we tested whether this altered perceptual processing affects their reversal dynamics and reduces the perceptual bias during Necker cube observation...
2017: PloS One
https://www.readbyqxmd.com/read/29244720/functional-imaging-with-18f-fdg-pet-ct-and-diffusion-weighted-imaging-dwi-in-early-response-evaluation-of-combination-therapy-of-elotuzumab-lenalidomide-and-dexamethasone-in-a-relapsed-multiple-myeloma-patient
#3
Christos Sachpekidis, Antonia Dimitrakopoulou-Strauss, Stefan Delorme, Hartmut Goldschmidt
Elotuzumab is the first monoclonal antibody approved for the treatment of relapsed-refractory multiple myeloma (MM) in combination with lenalidomide, an immunodulatory drug, and dexamethasone. We report on a multiply pre-treated MM patient with disease progression due to appearance of new focal lesions on imaging modalities, who was started on a combination treatment of elotuzumab, lenalidomide, and dexamethasone. After completion of three cycles of the new therapy the patient responded very well with a major decline of serological myeloma activity parameters serum monoclonal protein, kappa light chains, free light chains (FLC) ratio...
December 15, 2017: Diagnostics
https://www.readbyqxmd.com/read/29244636/event-related-electroencephalographic-lateralizations-mark-individual-differences-in-spatial-and-nonspatial-visual-selection
#4
Iris Wiegand, Natan Napiorkowski, Thomas Töllner, Anders Petersen, Thomas Habekost, Hermann J Müller, Kathrin Finke
Selective attention controls the distribution of our visual system's limited processing resources to stimuli in the visual field. Two independent parameters of visual selection can be quantified by modeling an individual's performance in a partial-report task based on the computational theory of visual attention (TVA): (i) top-down control α, the relative attentional weighting of relevant over irrelevant stimuli, and (ii) spatial bias wλ, the relative attentional weighting of stimuli in the left versus right hemifield...
December 15, 2017: Journal of Cognitive Neuroscience
https://www.readbyqxmd.com/read/29244202/mental-health-risk-adjustment-with-clinical-categories-and-machine-learning
#5
Akritee Shrestha, Savannah Bergquist, Ellen Montz, Sherri Rose
OBJECTIVE: To propose nonparametric ensemble machine learning for mental health and substance use disorders (MHSUD) spending risk adjustment formulas, including considering Clinical Classification Software (CCS) categories as diagnostic covariates over the commonly used Hierarchical Condition Category (HCC) system. DATA SOURCES: 2012-2013 Truven MarketScan database. STUDY DESIGN: We implement 21 algorithms to predict MHSUD spending, as well as a weighted combination of these algorithms called super learning...
December 15, 2017: Health Services Research
https://www.readbyqxmd.com/read/29243754/recycling-of-zincite-zno-via-uptake-of-hydrogen-halides
#6
Oday H Ahmed, Mohammednoor Altarawneh, Mohammad Al-Harahsheh, Zhong-Tao Jiang, Bogdan Z Dlugogorski
Hydrogen halides (HCl/HBr) represent major halogen fragments from the thermal decomposition of halogen laden materials, most notably PVC and brominated flame retardants (BFRs). Co-pyrolysis of halogen-containing solid waste with metal oxides is currently deployed as a mainstream strategy to treat halogen content as well as to recycle the valuable metallic fraction embedded in electric arc furnace dust (EAFD) and e-waste. However, designing an industrial-scale recycling facility necessitates accurate knowledge on mechanistic and thermo-kinetic parameters dictating the interaction between metal oxides and hydrogen halides...
December 15, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29243457/the-surgical-management-of-obesity
#7
Samuel Torres-Landa, Umashankkar Kannan, Isabella Guajardo, Octavia E Pickett-Blakely, Daniel T Dempsey, Noel N Williams, Kristoffel R Dumon
Obesity is a spreading epidemic associated with significant morbidity and mortality with a prevalence of over 36% worldwide. In the face of a growing epidemic, increasing medical costs, and the disappointing limitations of medical and lifestyle modification bariatric surgery was found to consistently lead to significant weight loss and improvement in obesity-associated comorbidities when compared to non-surgical interventions. Bariatric procedures fall within three basic categories: restrictive procedures, malabsorptive procedures, and procedures that combine both restrictive and malabsorptive mechanisms...
December 14, 2017: Minerva Chirurgica
https://www.readbyqxmd.com/read/29243190/faltering-growth-in-the-critically-ill-child-prevalence-risk-factors-and-impaired-outcome
#8
Frédéric V Valla, Julien Berthiller, Bénédicte Gaillard-Le-Roux, Carole Ford-Chessel, Tiphanie Ginhoux, Shancy Rooze, Fleur Cour-Andlauer, Rosan Meyer, Etienne Javouhey
Low body mass index (BMI) z score is commonly used to define undernutrition, but faltering growth allows for a complementary dynamic assessment of nutritional status. We studied the prevalence of undernutrition and faltering growth at admission in the pediatric intensive care (PICU) setting and their impacts on outcome. All (685) consecutive children (aged 0 to 18 years old) admitted in a single-center PICU over a 1-year period were prospectively enrolled. Nutritional status assessment was based on anthropometric measurements performed at admission and collected from medical files...
December 14, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29243101/fractures-in-a-nationwide-population-based-cohort-of-users-of-breast-cancer-hormonal-therapy
#9
Joan M Neuner, Yushu Shi, Amanda L Kong, Sailaja Kamaraju, Elizabeth C Smith, Alicia J Smallwood, Purushottam W Laud, John A Charlson
PURPOSE: Although users of aromatase inhibitors have higher total fracture risk in some randomized trials, little is known about their risk outside of clinical trials or in older higher-risk cohorts. METHODS: In a population-based retrospective cohort study, we identified all older US Medicare D prescription drug insurance plan-enrolled women who had initial breast cancer surgery in 2006-2008 and began hormonal therapy (an aromatase inhibitor (AI) or tamoxifen) within the subsequent year...
December 15, 2017: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/29242788/obturator-dislocation-of-hip-with-ipsilateral-fracture-neck-femur-a-case-report
#10
Sumit Kumar Jain, Parit Aggarwal, Arun Yadav
Introduction: Traumatic dislocation of the hip with ipsilateral fracture neck femur is a rare injury because of the different mechanism of both these injuries. The management of such injuries is a challenge as the chances of nonunion and avascular necrosis of femoral head are very high with fixation methods. We report a case of obturator dislocation of the hip with ipsilateral fracture neck of the femur which was treated with uncemented total hip replacement. Case Report: A 32-year-old male sustained obturator dislocation with ipsilateral fracture neck femur following road traffic accident...
September 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/29242571/divergent-risk-factors-for-cerebellar-and-intraventricular-hemorrhage
#11
Zachary A Vesoulis, Maja Herco, Amit M Mathur
OBJECTIVE: To identify whether intraventricular hemorrhage (IVH) and cerebellar hemorrhage (CH) have common or divergent risk factors. STUDY DESIGN: This is a retrospective cross-sectional cohort of infants including all infants born <30 weeks from 2007 to 2016. Comprehensive perinatal and clinical factors were extracted from the medical record. Outborn infants, infants with major congenital anomaly, those transferred prior to discharge, and those with mixed or no brain injury were excluded...
December 15, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29242349/efficacy-and-safety-of-itca-650-a-novel-drug-device-glp-1-receptor-agonist-in-type-2-diabetes-uncontrolled-with-oral-antidiabetes-drugs-the-freedom-1-trial
#12
Julio Rosenstock, John B Buse, Rehan Azeem, Prakash Prabhakar, Lise Kjems, Holly Huang, Michelle A Baron
OBJECTIVE: ITCA 650 (exenatide in osmotic mini-pump) continuously delivers exenatide subcutaneously for 3-6 months. Two doses of ITCA 650 were compared with placebo in patients with uncontrolled type 2 diabetes. RESEARCH DESIGN AND METHODS: This 39-week, phase 3, double-blind, placebo-controlled trial randomized 460 patients aged 18-80 years with glycated hemoglobin (HbA1c) 7.5-10% [58-86 mmol/mol] 1:1:1 to placebo, ITCA 650 40 μg/day, or ITCA 650 60 μg/day. Primary end point was change in HbA1c at 39 weeks...
December 14, 2017: Diabetes Care
https://www.readbyqxmd.com/read/29242110/initiation-of-traditional-cigarette-smoking-after-electronic-cigarette-use-among-tobacco-na%C3%A3-ve-u-s-young-adults
#13
Brian A Primack, Ariel Shensa, Jaime E Sidani, Beth L Hoffman, Samir Soneji, James D Sargent, Robert Hoffman, Michael J Fine
BACKGROUND: While electronic cigarettes (e-cigarettes) may help some smokers quit, some young adult never-smokers are now using e-cigarettes recreationally, potentially increasing their risk for initiation of smoking. We aimed to determine the association between baseline e-cigarette use and subsequent initiation of cigarette smoking among initially never-smoking young adults. METHODS: We conducted a prospective cohort study with assessments at baseline (March 2013) and follow-up (October 2014)...
November 17, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/29241659/a-novel-method-for-predicting-kidney-stone-type-using-ensemble-learning
#14
Yassaman Kazemi, Seyed Abolghasem Mirroshandel
The high morbidity rate associated with kidney stone disease, which is a silent killer, is one of the main concerns in healthcare systems all over the world. Advanced data mining techniques such as classification can help in the early prediction of this disease and reduce its incidence and associated costs. The objective of the present study is to derive a model for the early detection of the type of kidney stone and the most influential parameters with the aim of providing a decision-support system. Information was collected from 936 patients with nephrolithiasis at the kidney center of the Razi Hospital in Rasht from 2012 through 2016...
December 11, 2017: Artificial Intelligence in Medicine
https://www.readbyqxmd.com/read/29241518/influence-of-anthropometric-parameters-on-breastmilk-provision-in-preterm-infants
#15
Sharon G Casavant, Michelle Judge, Jacqueline McGrath
OBJECTIVE: To explore how growth trends may relate to maternal provision of breastmilk to preterm infants in the Neonatal Intensive Care Unit (NICU). DESIGN: Non-experimental, retrospective, descriptive. SETTING: Level III, 40-bed suburban neonatal intensive care unit (NICU). PARTICIPANTS: 94 preterm infants (<37 post-menstrual age) admitted to the NICU between September 2011 and May 2013. METHODS: This retrospective chart review explored the relationship between infant growth during hospitalization and maternal provision of breastmilk at discharge...
December 2017: Applied Nursing Research: ANR
https://www.readbyqxmd.com/read/29240978/biomimicry-of-volatile-based-microbial-control-for-managing-emerging-fungal-pathogens
#16
REVIEW
Kyle T Gabriel, Joseph D Sexton, Christopher T Cornelison
Volatile organic compounds (VOCs) are known to be produced by a wide range of microorganisms and for a number of purposes. Volatile-based microbial inhibition in environments such as soil is well-founded, with numerous antimicrobial VOCs having been identified. Inhibitory VOCs are of interest as microbial control agents, as low concentrations of gaseous VOCs can elicit significant antimicrobial effects. Volatile organic compounds are organic chemicals typically characterized as having low molecular weight, low solubility in water, and high vapor pressure...
December 14, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/29240835/scientific-research-on-animal-biodiversity-is-systematically-biased-towards-vertebrates-and-temperate-regions
#17
Mark A Titley, Jake L Snaddon, Edgar C Turner
Over the last 25 years, research on biodiversity has expanded dramatically, fuelled by increasing threats to the natural world. However, the number of published studies is heavily weighted towards certain taxa, perhaps influencing conservation awareness of and funding for less-popular groups. Few studies have systematically quantified these biases, although information on this topic is important for informing future research and conservation priorities. We investigated: i) which animal taxa are being studied; ii) if any taxonomic biases are the same in temperate and tropical regions; iii) whether the taxon studied is named in the title of papers on biodiversity, perhaps reflecting a perception of what biodiversity is; iv) the geographical distribution of biodiversity research, compared with the distribution of biodiversity and threatened species; and v) the geographical distribution of authors' countries of origin...
2017: PloS One
https://www.readbyqxmd.com/read/29240778/biopsychosocial-predictors-of-perceived-life-expectancy-in-a-national-sample-of-older-men-and-women
#18
Lindsay C Kobayashi, Rebecca J Beeken, Susanne F Meisel
Perceived life expectancy (PLE) is predictive of mortality risk in older adults, but the factors that may contribute to mental conceptions of PLE are unknown. We aimed to describe the sociodemographic, biomedical, behavioral, and psychological predictors of self-reported PLE estimates among older English adults. Data were from 6662 adults aged 50-79 years in the population-based English Longitudinal Study of Ageing (cross-sectional sample from 2012/13). PLE was assessed in the face-to-face study interview ("What are the chances you will live to be age x or more?" where x = current age plus 10-15 years)...
2017: PloS One
https://www.readbyqxmd.com/read/29240744/an-osteoarthritis-model-of-care-should-be-a-national-priority-for-new-zealand
#19
Jennifer Baldwin, Andrew Briggs, Warwick Bagg, Peter Larmer
Osteoarthritis is highly prevalent, disabling and costly to the person and the community. The burden of this chronic condition is predicted to increase dramatically over the coming decades. Healthcare spending on osteoarthritis is unsustainable and action is needed to improve care delivery. At present, there is an over-emphasis on surgical and pharmacological interventions, despite evidence supporting conservative treatments such as exercise, weight loss and education. While clinical guidelines provide recommendations regarding best practice (ie, what to do), they fail to address how to operationalise these recommendations into clinical practice...
December 15, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29240683/development-and-validation-of-the-brief-folate-specific-food-frequency-questionnaire-for-young-women-s-diet-assessment
#20
Dominika Głąbska, Aneta Książek, Dominika Guzek
The tools enabling brief assessment of folate intake may be of great value for public health purposes. The aim of the presented study was to design a brief folate-specific food frequency questionnaire for Central and Eastern European population of women, as well as to assess the validity and reproducibility of the designed Folate-Intake Calculation-Food Frequency Questionnaire (Fol-IC-FFQ) on a group of Polish women aged 20-30 years. Participants collected 3-day dietary records and completed the Fol-IC-FFQ twice (FFQ1: directly after the dietary record; and FFQ2: six weeks later)...
December 14, 2017: International Journal of Environmental Research and Public Health
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