Lucas A Zena, Andreas Tommy Ekström, Daniel Morgenroth, Tristan McArley, Michael Axelsson, Henrik Sundh, Anders Palmquist, Ida B Johansen, Albin Gräns, Erik Sandblom
Salmonid fish include some of the most valued cultured fish species worldwide. Unlike most other fish, the hearts of salmonids, including Atlantic salmon and rainbow trout, have a well-developed coronary circulation. Consequently, their hearts' reliance on oxygenation through coronary arteries leaves them prone to coronary lesions, believed to precipitate myocardial ischemia. Here, we mimicked such coronary lesions by subjecting groups of juvenile rainbow trout to coronary ligation, assessing histo-morphological myocardial changes associated with ischemia and scarring in the context of cardiac arrhythmias using electrocardiography (ECG)...
February 26, 2024: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology