Jun Zhang, Xin Huang, Guoqing Wang, Xianjun Wang, Tao Zhang, Dong Wang, Lifeng Qi, Jiye Liang, Bing Li, Jianfeng Chu, Kai Li, Lili Sun, Yun Song, Wei Zhao, Meimei Zheng, Yao Meng, Hao Yin, Wei Wang, Ju Han
BACKGROUND AND OBJECTIVES: Acute stent thrombosis (AST) is not uncommon and even catastrophic during intracranial stenting angioplasty in patients with symptomatic high-grade intracranial atherosclerotic stenosis (ICAS). The purpose of this study was to investigate whether adjuvant intravenous tirofiban before stenting could reduce the risk of AST and periprocedural ischemic stroke in patients receiving stent angioplasty for symptomatic ICAS. METHODS: A prospective, multicenter, open-label, randomized clinical trial was conducted from September 9, 2020, to February 18, 2022, at 10 medical centers in China...
April 9, 2024: Neurology