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https://www.readbyqxmd.com/read/29783267/-conceptual-approaches-to-the-investigation-of-a-problem-of-professional-training-of-physical-therapists
#1
Anna V Fastivetz, Pavlo V Khomenko, Inna E Shaparenko
OBJECTIVE: Introduction:The level of people's health and its preservation is a medical problem that requires the optimal solution and the need to improve the management of the system of measures to achieve the goal. According to specialists, the health of Ukrainian people is accompanied by high mortality, significant parameters of disability and morbidity and a decrease in the average life expectancy. Diseases that lead to such negative medical and social and socio-economic consequences are so-called "illnesses of a way of life" or "diseases of civilization"...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783266/multiorgan-failure-syndrome-in-newborns-role-of-social-and-anatomico-functional-features-literature-review
#2
Dmytro A Skurupii, Evgeniy G Sonnyk, Vitaliy M Sizonenko
Protection of maternal health as well as protection of fetal and newborn health is a strategic objective in all countries. It ensures the formation of healthy generation as the basis of gene pool preservation and further development of the nation. It is known that the progress of critical conditions in newborns is different from classical concepts. Аnatomicofunctional features of the newborns (especially premature newborns), the effect of prenatal pathological factors are provocative and background factors of the multiorgan failure syndrome begining in these patients, which probably affects frequency of appearance of this syndrome, the mechanisms of development, clinical manifestations, the final of the disease and makes doctors to consider newborns in critical conditions as high-risk group for multiorgan failure syndrome appearance...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783265/-international-experience-in-the-legal-regulation-of-the-circulation-of-medicines-through-the-prism-of-the-law-of-the-world-trade-organization
#3
Olena V Pasechnyk, Nataliia V Hendel
OBJECTIVE: Introduction: The development of international legal cooperation in the field of health has largely been driven by the trade interests of states. The aim: The article analyzes the legal regulation of the circulation of medicines through the prism of the law of the World Trade Organization. PATIENTS AND METHODS: Materials and methods: Using the historical legal method has allowed to analyze the genesis of legal regulation of the circulation of medicines through the prism of the law of the World Trade Organization...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783264/the-use-of-immunohistochemical-methods-in-the-study-of-morphofunctional-features-of-the-human-paranasal-sinuses-literature-review
#4
Mykhailo M Koptev, Nataliia I Vynnyk, Oksana V Kokovska, Olena М Pronina, Serhii М Bilash
OBJECTIVE: Introduction:Chronic inflammatory diseases of the mucous membrane of the nose, paranasal sinuses, and pharynx are the most widespread pathology of the upper airways. The thorough study of the features of the organization of local immune protection of the mucous membrane of the paranasal sinuses is crucial for the deep understanding of the causes of the onset and development of this and other pathologies of the paranasal sinuses, the choice of methods of diagnostics and treatment...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783263/monitoring-of-efficiency-of-dental-caries-management-in-children-s-temporary-teeth-throughout-poltava-oblast
#5
Olha V Sheshukova, Valentina P Trufanova, Tetiana V Polishchuk, Kateryna S Kazakova, Sofiya S Bauman, Natalia A Lyakhova, Iryna M Tkachenko
OBJECTIVE: Introduction: Dental caries is still a major health care problem not only in Ukraine but throughout the world. Complicated dental caries currently ranks the leading position among the oral diseases in children. The aim of this study is to carry out a analysis of the epidemiology of dental caries and its complications, and to evaluate the efficiency of the caries treatment for temporary teeth among the children of Poltava oblast over the last decade based on the data of the annual reports...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783261/epidemiology-of-acute-myocardial-infarction-in-ukraine-and-poltava-region
#6
Viacheslav M Zhdan, Grigory А Oksak, Oleh V Radomskyi, Denis I Shaposhnikov
OBJECTIVE: Introduction: The number of elderly people in society is increasing. Alike in all European countries, ageing population in Ukraine is observed, which affects the structure and dynamics of morbidity and mortality of the population towards the increase of chronic non-communicable diseases, which is the epidemic of the 21st century civilization. In 2010 in Ukraine, the proportion of people over the age of 60 was 20.6% of the total. The prevalence of all diseases among the elderly in 2010 amounted to 283522,8, and among the general population - 186746,4...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783260/-methods-of-diagnosis-of-non-specific-and-specific-lymphideniates-of-the-jaw-facial-part-in-children-literature-review
#7
Pavlo I Tkachenko, Yurii B Lobach, Sergii O Bilokon, Vitalina O Dobroskok, Yuliia V Popelo
OBJECTIVE: Introduction: Insufficient basic knowledge on the mechanisms of the multifactoral etiology and pathogenesis of various forms of maxillofacial lymphadenitis of odontogenic and non-odontogenic nature in children causes difficulties in making differential diagnosis. The algorithm of their examination involves a large number of methods, each of which has its own advantages and disadvantages with variable informativeness, depending on the particular situation. The aim: The paper is aimed atfamiliarization of broad medical public with informativeness of diagnostic measures in the nonspecific and specific affection of lymph nodes of the maxillofacial area in children...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783259/classifications-of-temporomandibular-disorders-and-patients-examination-protocols-comparative-analysis-by-the-convenience-of-their-daily-use-in-clinical-practice
#8
Ulyana D Telishevska, Oksana D Telishevska
OBJECTIVE: Introduction:The problem of temporomandibular disorders (TMD) is relevant in today's world and is considered one of the most common pathologies causing nonodontogenic pain syndromes of maxillofacial region. The morbidity of temporomandibular disorders is 27 to 76% among patients who seek dental care. There is now a significant number of classifications of TMD, however, clinically convenient, morphologically and pathogenetically substantiated classification of temporomandibular joint's (TMJ) conditions has not yet been developed...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783257/burden-of-premature-mortality-caused-by-four-main-non-communicable-diseases-in-ukraine
#9
Natalia O Ryngach, Lyubov Y Vlasyk
OBJECTIVE: Introduction: The scale and socio-economic implications of the non-communicable diseases (NCD) epidemic are growing in Ukraine. The aim: To determine the mode of mortality resulted from main non-communicable diseases in Ukraine, calculate and estimate the number of years of potential life lost (YPLL) due to premature mortality from them. PATIENTS AND METHODS: Materials and Methods: The information base of the study was official data of the State Statistics Service of Ukraine on the distribution of the deceased by gender, age groups and causes of death in 2016 and World Health Statistics 2016 data...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783254/-legal-bases-of-vaccination-in-ukraine
#10
Olena O Terzi
OBJECTIVE: Introduction: Despite the extraordinary progress made in the field of vaccination, a large number of children in the last decade, 24 million children, or nearly 20% of children born every year, do not receive a full plan for vaccination during their first year of life. The aim: The purpose of the article is to analyze the legal framework of vaccination in Ukraine, comparing the approach of the domestic legislator to the vaccination with foreign experience. PATIENTS AND METHODS: Materials and methods: Methods of research are selected based on the goal of the study...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783081/recent-technological-advancements-in-tuberculosis-diagnostics-a-review
#11
REVIEW
Shagun Gupta, Vipan Kakkar
Early diagnosis and on-time effective treatment are indispensable for Tuberculosis (TB) control - a life threatening infectious communicable disease. The conventional techniques for diagnosing TB normally take two to three weeks. This delay in diagnosis and further increase in detection complexity due to the emerging risks of XDR-TB (Extensively drug Resistant-TB) and MDR-TB (Multidrug Resistant-TB) are evoking interest of researchers in the field of developing rapid TB detection techniques such as biosensing and other point-of-care (POC) techniques...
May 11, 2018: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29783069/association-between-the-rs1143634-polymorphism-in-interleukin-1b-and-chronic-periodontitis-results-from-a-meta-analysis-composed-by-54-case-control-studies
#12
REVIEW
Felipe Rodolfo Pereira da Silva, Any Carolina Cardoso Guimarães Vasconcelos, Luiz Felipe de Carvalho França, David Di Lenardo, Hélio Mateus Silva Nascimento, Daniel Fernando Pereira Vasconcelos
Several factors are involved in the periodontitis with host response through cytokines and as well as with influence of polymorphisms in cytokine genes, however the results remained contradictory. This study aimed at evaluating the rs1143634 polymorphism in interleukin-1B gene, a cytokine gene, and the risk of chronic periodontitis with conducting a meta-analysis focusing in ethnicity. A review in literature was performed in several databases to studies published before June 2017. Data extraction was performed by two calibrated investigators and the calculations of the meta-analysis were obtained through Review Manager version 5...
May 18, 2018: Gene
https://www.readbyqxmd.com/read/29783067/motor-retraining-more-for-functional-movement-disorders-outcomes-from-a-one-week-multidisciplinary-rehabilitation-program
#13
Alexandra Jacob, Darryl Kaelin, Abbey Roach, Craig Ziegler, Kathrin LaFaver
BACKGROUND: Functional Movement Disorders (FMD) are conditions of abnormal motor control thought to be caused by psychological factors. These disorders are commonly seen in neurological practice and prognosis is often poor. No consensus treatment guidelines have been established, however the role of physical therapy in addition to psychotherapy has increasingly been recognized. This study reports patient outcomes from a multidisciplinary FMD treatment program using motor retraining (MoRe) strategies...
May 18, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29783031/a-unique-all-payer-rate-setting-system-controls-the-cost-but-not-the-racial-disparity-in-lower-extremity-revascularization-procedures
#14
Besma Nejim, Robert J Beaulieu, Husain Alshaikh, Mohammed Hamouda, Joseph Canner, Mahmoud B Malas
BACKGROUND: Patients with peripheral arterial disease (PAD) often have high comorbidity burden that may complicate post-interventional course and drive increased healthcare expenditures. Racial disparity had been observed in lower extremity revascularization (LER) patterns and outcomes. In 2014, Maryland adopted an all-payer rate setting system to limit the rising hospitalization costs. This resulted in an aggregate payment system in which hospital compensation takes place as an overall per capita expenditure for hospital services...
May 18, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29783026/a-prolonged-and-large-outbreak-of-invasive-group-a-streptococcal-disease-within-a-nursing-home-repeated-intra-facility-transmission-of-a-single-strain
#15
S A Nanduri, B J Metcalf, M A Arwady, C Edens, M A Lavin, J Morgan, W Clegg, A Beron, J P Albertson, R Link-Gelles, A Ogundimu, J Gold, D Jackson, S Chochua, N Stone, C Van Beneden, K Fleming-Dutra, B Beall
OBJECTIVES: Multiple invasive group A streptococcal (GAS) infections were reported to public health by a skilled nursing facility (Facility A) in Illinois between May 2014 and August 2016. Cases continued despite interventions including antibiotic prophylaxis for all residents and staff. Two other geographically close facilities reported contemporaneous outbreaks of GAS. We investigated potential reasons for ongoing transmission. METHODS: We obtained epidemiologic data from chart review of cases and review of facility and public health records from previous investigations into the outbreak...
May 18, 2018: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29783010/translaminar-approach-for-treatment-of-hidden-zone-foraminal-lumbar-disc-herniations-considerations-on-the-surgical-technique-and-pre-operative-selection-of-patients-with-a-long-term-follow-up
#16
Christian Cossandi, Andrea Fanti, Andrea Gerosa, Andrea Bianco, Riccardo Fornaro, Emanuela Crobeddu, Sara Forgnone, Gabriele Panzarasa, Andrea Di Cristofori
BACKGROUND: Lumbar disc herniation (LDH) is a common degenerative disease of the lumbar spine with a prevalence of 1-3% in population studies according to some authors. In 10% of patients there is a fragment migrated cranially in the Macnab's "hidden zone". In selected cases, this fragment can be removed with a translaminar approach that has been described in 1998. Aim of our work is to provide a detailed description of the technical advantages and pitfalls of such approach reviewing a consecutive series of patients...
May 18, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29782972/stat3-and-apoptosis-challenges-in-cancer
#17
REVIEW
Nazanin Fathi, Golnaz Rashdi, Simin Sharifi
Several studies have processed conceivable evidence for the vital role of Signal Transducer and Activator of Transcription 3 (STAT3) in cancer transformation and carcinogenesis. Therefore, one of the important factors in formation of cancer is STAT3 and for design of novel anticancer drugs is a suitable target. On the other hand, apoptosis pathway has a critical role in the cancers pathogenesis. Generally, increasing developments have been existed to expression, production, phosphorylation or activation of STAT3 in the effective or responsible cells of most of the cancers...
May 18, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29782944/a-comprehensive-review-on-contact-lens-for-ophthalmic-drug-delivery
#18
REVIEW
Jiawen Xu, Yingyan Xue, Gaoyong Hu, Tianyu Lin, Jingxin Gou, Tian Yin, Haibing He, Yu Zhang, Xing Tang
With the prevalence of electronic devices and an aging population, the number of people affected with eye disease is increasing year by year. In spite of a large number of eye drops on the market, most of them do not perform sufficiently, due to rapid clearance mechanisms and ocular barriers. To enhance drug delivery to the eye, a number of novel formulations for ocular diseases have been investigated over recent decades, aiming to increase drug retention and permeation while also allowing for sustained drug release over prolonged periods...
May 18, 2018: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/29782925/the-developmental-genetics-of-canalization
#19
REVIEW
Benedikt Hallgrimsson, Rebecca M Green, David Katz, Jennifer L Fish, Francois P J Bernier, Charles C Roseman, Nathan M Young, James M Cheverud, Ralph S Marcucio
Canalization, or robustness to genetic or environmental perturbations, is fundamental to complex organisms. While there is strong evidence for canalization as an evolved property that varies among genotypes, the developmental and genetic mechanisms that produce this phenomenon are very poorly understood. For evolutionary biology, understanding how canalization arises is important because, by modulating the phenotypic variation that arises in response to genetic differences, canalization is a determinant of evolvability...
May 18, 2018: Seminars in Cell & Developmental Biology
https://www.readbyqxmd.com/read/29782919/animal-models-to-study-bile-acid-metabolism
#20
REVIEW
Jianing Li, Paul A Dawson
The use of animal models, particularly genetically modified mice, continues to play a critical role in studying the relationship between bile acid metabolism and human liver disease. Over the past 20 years, these studies have been instrumental in elucidating the major pathways responsible for bile acid biosynthesis and enterohepatic cycling, and the molecular mechanisms regulating those pathways. This work also revealed bile acid differences between species, particularly in the composition, physicochemical properties, and signaling potential of the bile acid pool...
May 18, 2018: Biochimica et Biophysica Acta
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