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https://www.readbyqxmd.com/read/28532604/validation-of-dwi-pre-processing-procedures-for-reliable-differentiation-between-human-brain-gliomas
#1
Sebastian Vellmer, Aram S Tonoyan, Dieter Suter, Igor N Pronin, Ivan I Maximov
Diffusion magnetic resonance imaging (dMRI) is a powerful tool in clinical applications, in particular, in oncology screening. dMRI demonstrated its benefit and efficiency in the localisation and detection of different types of human brain tumours. Clinical dMRI data suffer from multiple artefacts such as motion and eddy-current distortions, contamination by noise, outliers etc. In order to increase the image quality of the derived diffusion scalar metrics and the accuracy of the subsequent data analysis, various pre-processing approaches are actively developed and used...
May 19, 2017: Zeitschrift Für Medizinische Physik
https://www.readbyqxmd.com/read/28525383/histogram-analysis-of-diffusion-kurtosis-imaging-of-nasopharyngeal-carcinoma-correlation-between-quantitative-parameters-and-clinical-stage
#2
Xiao-Quan Xu, Gao Ma, Yan-Jun Wang, Hao Hu, Guo-Yi Su, Hai-Bin Shi, Fei-Yun Wu
PURPOSE: To evaluate the correlation between histogram parameters derived from diffusion-kurtosis (DK) imaging and the clinical stage of nasopharyngeal carcinoma (NPC). RESULTS: High T-stage (T3/4) NPC showed significantly higher Kapp-mean (P = 0.018), Kapp-median (P = 0.029) and Kapp-90th (P = 0.003) than low T-stage (T1/2) NPC. High N-stage NPC (N2/3) showed significantly lower Dapp-mean (P = 0.002), Dapp-median (P = 0.002) and Dapp-10th (P < 0.001) than low N-stage NPC (N0/1)...
May 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/28522257/can-ct-measures-of-tumour-heterogeneity-stratify-risk-for-nodal-metastasis-in-patients-with-non-small-cell-lung-cancer
#3
M Craigie, J Squires, K Miles
AIM: To undertake a preliminary assessment of the potential for computed tomography (CT) measurement of tumour heterogeneity to stratify risk of nodal metastasis in patients with non-small cell lung cancer (NSCLC). MATERIALS AND METHODS: Tumour heterogeneity in CT images from combined positron-emission tomography (PET)/CT examinations in 150 consecutive patients with NSCLC was assessed using CT texture analysis (CTTA). The short axis diameter of the largest mediastinal node was also measured...
May 15, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28515412/utility-of-a-hybrid-ivim-dki-model-to-predict-the-development-of-distant-metastasis-in-head-and-neck-squamous-cell-carcinoma-patients
#4
Noriyuki Fujima, Tomohiro Sakashita, Akihiro Homma, Daisuke Yoshida, Kohsuke Kudo, Hiroki Shirato
PURPOSE: To evaluate the diagnostic power of hybrid intravoxel incoherent motion (IVIM)-diffusion kurtosis imaging (DKI) model parameters in pretreatment for the prediction of future distant metastasis in head and neck squamous cell carcinoma (HNSCC) patients. MATERIALS AND METHODS: We retrospectively evaluated 49 HNSCC patients who underwent curative chemoradiation therapy. Diffusion-weighted image (DWI) acquired by single-shot spin-echo echo-planar imaging with 12 b-values (0-2000) was performed in all patients before any treatment...
May 18, 2017: Magnetic Resonance in Medical Sciences: MRMS
https://www.readbyqxmd.com/read/28514763/the-value-of-diffusion-kurtosis-imaging-in-assessing-pathological-complete-response-to-neoadjuvant-chemoradiation-therapy-in-rectal-cancer-a-comparison-with-conventional-diffusion-weighted-imaging
#5
Feixiang Hu, Wei Tang, Yiqun Sun, Dang Wan, Sanjun Cai, Zhen Zhang, Robert Grimm, Xu Yan, Caixia Fu, Tong Tong, Weijun Peng
OBJECTIVES: The aim of this study is to comprehensively evaluate the advantage of diffusion kurtosis imaging (DKI) in distinguishing pathological complete response (pCR) from non-pCR patients with locally advanced rectal cancer (LARC) after neoadjuvant chemoradiation therapy (CRT) in comparison to conventional diffusion-weighted imaging (DWI). MATERIAL AND METHODS: Fifty-six consecutive patients diagnosed with LARC were prospectively enrolled and underwent pre- and post-CRT MRI on a 3...
April 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/28513853/association-between-textural-and-morphological-tumor-indices-on-baseline-pet-ct-and-early-metabolic-response-on-interim-pet-ct-in-bulky-malignant-lymphomas
#6
Fayçal Ben Bouallègue, Yassine Al Tabaa, Marilyne Kafrouni, Guillaume Cartron, Fabien Vauchot, Denis Mariano-Goulart
PURPOSE: We investigated whether metabolic, textural and morphological tumoral indices evaluated on baseline PET-CT were predictive of early metabolic response on interim PET-CT in a cohort of patients with bulky Hodgkin and non-Hodgkin malignant lymphomas. METHODS: This retrospective study included 57 patients referred for initial PET-CT examination. In-house dedicated software was used to delineate tumor contours using a fixed 30% threshold of SUV max and then to compute tumoral metabolic parameters (SUV max, mean, peak, standard deviation, skewness and kurtosis, metabolic tumoral volume (MTV), total lesion glycolysis, and area under the curve of the cumulative histogram), textural parameters (Moran's and Geary's indices, energy, entropy, contrast, correlation derived from the gray-level co-occurrence matrix, area under the curve of the power spectral density, auto-correlation distance, and granularity), and shape parameters (surface, asphericity, convexity, surfacic extension, and 2D and 3D fractal dimensions)...
May 17, 2017: Medical Physics
https://www.readbyqxmd.com/read/28509567/early-evaluation-of-radiation-induced-parotid-damage-with-diffusion-kurtosis-imaging-a-preliminary-study
#7
Nan Zhou, Weibo Chen, Xia Pan, Jian He, Jing Yan, Zhengyang Zhou, Xiaofeng Yang
Background Radiation-induced parotid gland damage is a common complication of radiotherapy (RT) in patients with nasopharyngeal carcinoma (NPC), which always causes xerostomia, dysphagia, dental caries, and even sleep disorders. Early evaluation of radiation-induced parotid damage is required to facilitate early interventions. Purpose To early-evaluate radiation-induced parotid damage using diffusion kurtosis imaging (DKI) in patients with NPC undergoing RT. Material and Methods Thirty-two patients with NPC underwent DKI for parotid glands pre-RT (two weeks before RT), mid-RT (five weeks after RT began), and post-RT (four weeks after RT)...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28508679/comparison-of-fdg-pet-metabolic-tumour-volume-versus-adc-histogram-prognostic-value-of-tumour-treatment-response-and-survival-in-patients-with-locally-advanced-uterine-cervical-cancer
#8
Yoshiko Ueno, Robert Lisbona, Tsutomu Tamada, Amer Alaref, Kazuro Sugimura, Caroline Reinhold
OBJECTIVE: To evaluate the prognostic utility of volume-based parameters of fluorine 18 fluorodeoxyglucose positron emission tomography ((18)F-FDG PET) and apparent diffusion coefficient (ADC) histogram analysis for tumour response to therapy and event-free survival (EFS) in patients with uterine cervical cancer receiving chemoradiotherapy (CRT). METHODS: The study included 21 patients diagnosed as locally advanced uterine cervical cancer who underwent pre-treatment MRI and (18)F-FDG PET and were treated with concurrent CRT...
May 16, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28508489/prediction-of-whole-genome-risk-for-selection-and-management-of-hyperketonemia-in-holstein-dairy-cattle
#9
K A Weigel, R S Pralle, H Adams, K Cho, C Do, H M White
Hyperketonemia (HYK), a common early postpartum health disorder characterized by elevated blood concentrations of β-hydroxybutyrate (BHB), affects millions of dairy cows worldwide and leads to significant economic losses and animal welfare concerns. In this study, blood concentrations of BHB were assessed for 1,453 Holstein cows using electronic handheld meters at four time points between 5 and 18 days postpartum. Incidence rates of subclinical (1.2 ≤ maximum BHB ≤ 2.9 mmol/L) and clinical ketosis (maximum BHB ≥ 3...
June 2017: Journal of Animal Breeding and Genetics, Zeitschrift Für Tierzüchtung und Züchtungsbiologie
https://www.readbyqxmd.com/read/28497987/elevated-activating-transcription-factor-4-and-glucose-regulated-78-kda-protein-levels-correlate-with-inflammatory-cytokines-in-the-aqueous-humor-and-vitreous-of-proliferative-diabetic-retinopathy
#10
Yanuo Wang, Sha Gao, Yanji Zhu, Xi Shen
PURPOSE: To determine concentrations of endoplasmic reticulum (ER) stress-related factors activating transcription factor 4 (ATF4) and glucose-regulated 78 kDa protein (GRP78) in vitreous and aqueous humor (AqH) of patients with proliferative diabetic retinopathy (PDR) and the correlation of ATF4, GRP78 and inflammatory cytokines interleukin-6(IL-6) and monocyte chemoattractant protein-1 (MCP-1). MATERIALS AND METHODS: AqH and vitreous samples were collected from eyes of patients with PDR and idiopathic macular hole (IMH) which needed vitrectomy...
May 12, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28497123/functional-trait-diversity-maximizes-ecosystem-multifunctionality
#11
Nicolas Gross, Yoann Le Bagousse-Pinguet, Pierre Liancourt, Miguel Berdugo, Nicholas J Gotelli, Fernando T Maestre
Understanding the relationship between biodiversity and ecosystem functioning has been a core ecological research topic over the last decades. Although a key hypothesis is that the diversity of functional traits determines ecosystem functioning, we do not know how much trait diversity is needed to maintain multiple ecosystem functions simultaneously (multifunctionality). Here, we uncovered a scaling relationship between the abundance distribution of two key plant functional traits (specific leaf area, maximum plant height) and multifunctionality in 124 dryland plant communities spread over all continents except Antarctica...
May 2017: Nat Ecol Evol
https://www.readbyqxmd.com/read/28495001/a-comparison-between-swallowing-sounds-and-vibrations-in-patients-with-dysphagia
#12
Faezeh Movahedi, Atsuko Kurosu, James L Coyle, Subashan Perera, Ervin Sejdić
The cervical auscultation refers to the observation and analysis of sounds or vibrations captured during swallowing using either a stethoscope or acoustic/vibratory detectors. Microphones and accelerometers have recently become two common sensors used in modern cervical auscultation methods. There are open questions about whether swallowing signals recorded by these two sensors provide unique or complementary information about swallowing function; or whether they present interchangeable information. This study aims to compare of swallowing signals recorded by a microphone and a tri-axial accelerometer from 72 patients (mean age 63...
June 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28490790/entropy-of-radiation-the-unseen-side-of-light
#13
Alfonso Delgado-Bonal
Despite the fact that 2015 was the international year of light, no mention was made of the fact that radiation contains entropy as well as energy, with different spectral distributions. Whereas the energy function has been vastly studied, the radiation entropy distribution has not been analysed at the same speed. The Mode of the energy distribution is well known -Wien's law- and Planck's law has been analytically integrated recently, but no similar advances have been made for the entropy. This paper focuses on the characterization of the entropy of radiation distribution from an statistical perspective, obtaining a Wien's like law for the Mode and integrating the entropy for the Median and the Mean in polylogarithms, and calculating the Variance, Skewness and Kurtosis of the function...
May 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28485734/the-effect-of-crack-cocaine-addiction-and-age-on-the-microstructure-and-morphology-of-the-human-striatum-and-thalamus-using-shape-analysis-and-fast-diffusion-kurtosis-imaging
#14
E A Garza-Villarreal, M M Chakravarty, B Hansen, S F Eskildsen, G A Devenyi, D Castillo-Padilla, T Balducci, E Reyes-Zamorano, S N Jespersen, P Perez-Palacios, R Patel, J J Gonzalez-Olvera
The striatum and thalamus are subcortical structures intimately involved in addiction. The morphology and microstructure of these have been studied in murine models of cocaine addiction (CA), showing an effect of drug use, but also chronological age in morphology. Human studies using non-invasive magnetic resonance imaging (MRI) have shown inconsistencies in volume changes, and have also shown an age effect. In this exploratory study, we used MRI-based volumetric and novel shape analysis, as well as a novel fast diffusion kurtosis imaging sequence to study the morphology and microstructure of striatum and thalamus in crack CA compared to matched healthy controls (HCs), while investigating the effect of age and years of cocaine consumption...
May 9, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28484279/diffusion-kurtosis-imaging-of-microstructural-alterations-in-the-brains-of-paediatric-patients-with-congenital-sensorineural-hearing-loss
#15
Wenbin Zheng, Chunxiao Wu, Lexing Huang, Renhua Wu
Our aim was to assess microstructural alterations in the cerebrums of paediatric patients with congenital sensorineural hearing loss (SNHL) using diffusion kurtosis imaging (DKI). Seventy-two paediatric SNHL patients and 38 age-matched healthy volunteers were examined via DKI using a 3.0 T magnetic resonance (MR) imager. Fractional anisotropy (FA) and mean kurtosis (MK) values were computed for 12 cerebral regions in both the controls and the SNHL patients. Compared with patients below age 3, patients in the older age group were found to have more significant differences in MK than in FA, and these appeared in more major areas of the brain...
May 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28483356/evaluation-of-a-breast-software-model-for-2d-and-3d-x-ray-imaging-studies-of-the-breast
#16
Yanka Baneva, Kristina Bliznakova, Lesley Cockmartin, Stoyko Marinov, Ivan Buliev, Giovanni Mettivier, Hilde Bosmans, Paolo Russo, Nicholas Marshall, Zhivko Bliznakov
INTRODUCTION: In X-ray imaging, test objects reproducing breast anatomy characteristics are realized to optimize issues such as image processing or reconstruction, lesion detection performance, image quality and radiation induced detriment. Recently, a physical phantom with a structured background has been introduced for both 2D mammography and breast tomosynthesis. A software version of this phantom and a few related versions are now available and a comparison between these 3D software phantoms and the physical phantom will be presented...
May 5, 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28482407/-value-of-texture-analysis-in-evaluating-liver-cancer-recurrence-after-transarterial-chemoembolization
#17
R Wang, X Y Yang, K Y Wang, S Wang, Q Li, J F Wu, H T Xu, Y Dai, C P Han, K Xu, G H Chen
Objective: To investigate the feasibility of contrast-enhanced computer tomography (CT) texture analysis in predicting early recurrence after transarterial chemoembolization (TACE) in patients with liver cancer. Methods: A retrospective analysis was performed for 47 patients with liver cancer confirmed by liver biopsy and digital subtraction angiography who underwent upper abdominal contrast-enhanced CT scan before TACE, and according to the presence or absence of focal recurrence within half a year, these patients were divided into early recurrence (ER) group and non-early recurrence (NER) group...
March 20, 2017: Zhonghua Gan Zang Bing za Zhi, Zhonghua Ganzangbing Zazhi, Chinese Journal of Hepatology
https://www.readbyqxmd.com/read/28480613/efficient-experimental-designs-for-isotropic-generalized-diffusion-tensor-mri-igdti
#18
Alexandru V Avram, Joelle E Sarlls, Elizabeth Hutchinson, Peter J Basser
PURPOSE: We propose a new generalized diffusion tensor imaging (GDTI) experimental design and analysis framework for efficiently measuring orientationally averaged diffusion-weighted images (DWIs), which remove bulk signal modulations attributed to diffusion anisotropy and quantify isotropic higher-order diffusion tensors (HOT). We illustrate how this framework accelerates the clinical measurement of rotation-invariant tissue microstructural parameters derived from HOT, such as the HOT-Trace and the mean t-kurtosis...
May 7, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28474533/ct-texture-analysis-of-ex-vivo-renal-stones-predicts-ease-of-fragmentation-with-shockwave-lithotripsy
#19
Helen Wei Cui, Wout Devlies, Samuel Ravenscroft, Hendrik Heers, Andrew Freidin, Robin Cleveland, Balaji Ganeshan, Ben W Turney
Introduction Understanding the factors affecting success of shock wave lithotripsy (SWL) would improve informed decision-making on the most appropriate treatment modality for an individual patient. Although stone size and skin-to-stone distance do correlate with fragmentation efficacy, it has been shown that stone composition and architecture, as reflected by structural heterogeneity on CT, are also important factors. This study aims to determine if CT Texture Analysis (CTTA)-a novel, non-destructive, and objective tool that generates statistical metrics reflecting stone heterogeneity-could have utility in predicting likelihood of SWL success...
May 5, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28473339/diffusional-kurtosis-imaging-and-motor-outcome-in-acute-ischemic-stroke
#20
M V Spampinato, C Chan, J H Jensen, J A Helpern, L Bonilha, S A Kautz, P J Nietert, W Feng
BACKGROUND AND PURPOSE: Motor impairment is the most common deficit after stroke. Our aim was to evaluate whether diffusional kurtosis imaging can detect corticospinal tract microstructural changes in the acute phase for patients with first-ever ischemic stroke and motor impairment and to assess the correlations between diffusional kurtosis imaging-derived diffusion metrics for the corticospinal tract and motor impairment 3 months poststroke. MATERIALS AND METHODS: We evaluated 17 patients with stroke who underwent brain MR imaging including diffusional kurtosis imaging within 4 days after the onset of symptoms...
May 4, 2017: AJNR. American Journal of Neuroradiology
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