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https://www.readbyqxmd.com/read/28820053/neurobiological-mechanisms-of-stress-resilience-and-implications-for-the-aged-population
#1
Charlène Faye, Josephine C Mcgowan, Christine A Denny, Denis J David
Stress is a common reaction to an environmental adversity, but a dysregulation of the stress response can lead to psychiatric illnesses such as major depressive disorder (MDD), post-traumatic stress disorder (PTSD), and anxiety disorders. Yet, not all individuals exposed to stress will develop psychiatric disorders; those with enhanced stress resilience mechanisms have the ability to adapt successfully to stress without developing persistent psychopathology. Notably, the potential to enhance stress resilience in at-risk populations may prevent the onset of stress-induced psychiatric disorders...
August 17, 2017: Current Neuropharmacology
https://www.readbyqxmd.com/read/28818717/the-effect-of-post-traumatic-stress-disorder-on-the-risk-of-developing-prescription-opioid-use-disorder-results-from-the-national-epidemiologic-survey-on-alcohol-and-related-conditions-iii
#2
Ahmed N Hassan, Bernard Le Foll, Sameer Imtiaz, Jürgen Rehm
OBJECTIVE: To evaluate the effect of baseline post-traumatic stress disorder (PTSD) and each symptoms cluster on the risk of developing opioid use disorder (OUD) in those exposed to opioid painkillers and to assess the effect of comorbid PTSD and OUD on functioning, OUD severity, and treatment seeking compared with individuals with OUD only. METHODS: We obtained data from 4025 individuals exposed to opioid painkillers from the National Epidemiologic Survey on Alcohol and Related Conditions III...
August 8, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28813322/anger-and-aggression-in-ptsd
#3
REVIEW
Casey T Taft, Suzannah K Creech, Christopher M Murphy
Trauma and posttraumatic stress disorder have massive negative consequences; associated anger and aggression are particularly damaging. This overview focuses on these relationships and their potential mechanisms, and offers treatment considerations. Research and theory suggests that trauma impacts anger and aggression through social information processing mechanisms, and an aggression model incorporating impelling, instigating, and disinhibiting factors helps us understand who is at risk under specific circumstances...
April 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28813309/theory-driven-models-of-self-directed-violence-among-individuals-with-ptsd
#4
REVIEW
Craig J Bryan, Jeremy L Grove, Nathan A Kimbrel
PTSD is a well-established risk factor for the full range of self-directed violence (SDV). It is also one of the few psychological conditions that distinguish those who think about suicide from those who attempt suicide. Despite considerable evidence supporting these points, very little is understood about the mechanisms by which PTSD increases the risk for SDV at the present time. This knowledge gap is largely due to the absence of research driven by empirically-supported models of suicide. More recently, this knowledge gap has been slowly filled by a growing number of studies informed by two particular conceptual models: the fluid vulnerability theory and the interpersonal psychological theory...
April 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28810979/women-veterans-a-population-at-risk-for-fibromyalgia-the-associations-between-fibromyalgia-symptoms-and-quality-of-life
#5
Rita F D'Aoust, Alicia Gill Rossiter, Amanda Elliott, Ming Ji, Cecile Lengacher, Maureen Groer
BACKGROUND: The Institute of Federal Health Care recently published an executive summary from a round table discussion indicating that active duty and retired female military personnel are at high risk for adverse health outcomes unique to military service including complications related to post-traumatic stress disorder (PTSD), unreported sexual trauma, and musculoskeletal problems. In 2008, the Institute of Medicine began to review, evaluate, and summarize the literature on health outcomes in Gulf War-deployed and found sufficient evidence of a causal relationship with PTSD and suggestive evidence of an association with fibromyalgia (FM)...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28805719/factors-affecting-depressive-symptoms-among-north-korean-adolescent-refugees-residing-in-south-korea
#6
Subin Park, Minji Lee, Jin Yong Jeon
We examined factors affecting the depressive symptoms and the relationship between depression and quality of life among 131 North Korean adolescent refugees aged 12-24 years. We compared sociodemographic, social, and individual characteristics and perceived the quality of life between participants with and without depression. Thirty-seven refugees (28.2%) had clinically significant depressive symptoms. The refugees with depression were younger (t = 2.67; p = 0.009), more likely to be male (χ² = 6.98; p = 0...
August 14, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28804594/does-trauma-event-type-matter-in-the-assessment-of-traumatic-load
#7
Daniela Conrad, Sarah Wilker, Anett Pfeiffer, Birke Lingenfelder, Tracie Ebalu, Hartmut Lanzinger, Thomas Elbert, Iris-Tatjana Kolassa, Stephan Kolassa
Background: The likelihood of developing Posttraumatic Stress Disorder (PTSD) depends on the interaction of individual risk factors and cumulative traumatic experiences. Hence, the identification of individual susceptibility factors warrants precise quantification of trauma exposure. Previous research indicated that some traumatic events may have more severe influences on mental health than others; thus, the assessment of traumatic load may be improved by weighting event list items rather than calculating the simple sum score...
2017: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/28799847/the-willingness-of-people-who-inject-drugs-in-boston-to-use-a-supervised-injection-facility
#8
Casey León, Lena Cardoso, Sarah Mackin, Barry Bock, Jessie M Gaeta
BACKGROUND: In Massachusetts, the number of opioid-related deaths has increased 350% since 2000. In the setting of increasing overdose deaths, one potential intervention is Supervised Injection Facilities (SIFs). This study explores willingness of people who inject drugs in Boston to use a SIF and examines factors associated with willingness. METHODS: A cross-sectional survey of a convenience sample of 237 people who inject drugs and utilize Boston's needle exchange program (NEP)...
August 11, 2017: Substance Abuse
https://www.readbyqxmd.com/read/28797932/when-social-support-is-not-enough-trauma-and-ptsd-symptoms-in-a-risk-sample-of-adolescents
#9
Ricardo J Pinto, Diogo Morgado, Sara Reis, Rita Monteiro, Alytia Levendosky, Inês Jongenelen
Social support can mitigate the severity of posttraumatic stress disorder (PTSD) in children and adults following traumatic events. However, little is known about the role of social support in high-risk samples of adolescents from the community. The present study examined the relationship between social support and PTSD symptoms in adolescents exposed to traumatic events and childhood adversity, after adjusting for the effects of potential covariates, including sociodemographic factors, previous childhood adversity, level of exposure, comorbid anxiety, depression symptoms, and substance abuse, and coping strategies...
August 7, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28768717/formin-2-links-neuropsychiatric-phenotypes-at-young-age-to-an-increased-risk-for-dementia
#10
Roberto Carlos Agís-Balboa, Paulo Pinhero, Nelson Rebola, Cemil Kerimoglu, Eva Benito, Michael Gertig, Sanaz Bahari-Javan, Gaurav Jain, Susanne Burkhardt, Ivana Delalle, Alexander Jatzko, Markus Dettenhofer, Patricia A Zunszain, Andrea Schmitt, Peter Falkai, Julius C Pape, Elisabeth B Binder, Christophe Mulle, Andre Fischer, Farahnaz Sananbenesi
Age-associated memory decline is due to variable combinations of genetic and environmental risk factors. How these risk factors interact to drive disease onset is currently unknown. Here we begin to elucidate the mechanisms by which post-traumatic stress disorder (PTSD) at a young age contributes to an increased risk to develop dementia at old age. We show that the actin nucleator Formin 2 (Fmn2) is deregulated in PTSD and in Alzheimer's disease (AD) patients. Young mice lacking the Fmn2 gene exhibit PTSD-like phenotypes and corresponding impairments of synaptic plasticity, while the consolidation of new memories is unaffected...
August 2, 2017: EMBO Journal
https://www.readbyqxmd.com/read/28767006/potentially-traumatic-events-as-predictors-of-disability-pension-a-10-year-follow-up-study-in-norway
#11
Eva Lassemo, Inger Sandanger
AIMS: Are potentially traumatic events associated with subsequent disability pension? Traumatic exposure and post-traumatic stress disorder (PTSD) may represent a disabling state with both personal and professional consequences for the affected individual. Despite this, there is a scarcity of research studying the effects of traumatic exposure on disability pension. This study examined the differences in risk for disability pension among unexposed, exposed to trauma and PTSD cases. METHODS: An ambidirectional Norwegian cohort study, consisting of 1238 individuals aged 18-66 years who were at risk of disability pension, were interviewed using the Composite International Diagnostic Interview, and linked with registry data on disability pension...
August 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/28758569/association-between-self-reported-sexually-transmitted-infection-treatment-and-mental-health-symptoms-in-conflict-affected-eastern-democratic-republic-of-the-congo
#12
Erica Koegler, Caitlin E Kennedy, Carol B Thompson, Peter J Winch, Remy M Mpanano, Nancy A Perrin, Nancy Glass
Although poor mental health has been associated with sexual risk behavior, few studies have examined the association between mental health and sexually transmitted infections (STIs) in conflict-affected settings. With elevated symptoms of poor mental health in conflict-affected settings, it is important to consider if and how mental health may be a risk factor for STIs in these settings. We used cross-sectional logistic regression to examine the association between symptoms of depression, anxiety, and post-traumatic stress disorder (PTSD) with having been treated for an STI in rural South Kivu, Democratic Republic of the Congo...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28742837/risk-factors-associated-with-posttraumatic-stress-disorder-in-us-veterans-a-cohort-study
#13
Jan Müller, Sarmila Ganeshamoorthy, Jonathan Myers
OBJECTIVE: To assess the association between clinical and exercise test factors and the development of posttraumatic stress disorder (PTSD) in US Veterans. PATIENTS AND METHODS: Exercise capacity, demographics and clinical variables were assessed in 5826 veterans (mean age 59.4 ± 11.5 years) from the Veterans Affairs Healthcare System in Palo Alto, CA. The study participants underwent routine clinical exercise testing between the years 1987 and 2011. The study end point was the development of PTSD...
2017: PloS One
https://www.readbyqxmd.com/read/28741810/gender-differences-in-machine-learning-models-of-trauma-and-suicidal-ideation-in-veterans-of-the-iraq-and-afghanistan-wars
#14
Jaimie L Gradus, Matthew W King, Isaac Galatzer-Levy, Amy E Street
Suicide rates among recent veterans have led to interest in risk identification. Evidence of gender-and trauma-specific predictors of suicidal ideation necessitates the use of advanced computational methods capable of elucidating these important and complex associations. In this study, we used machine learning to examine gender-specific associations between predeployment and military factors, traumatic deployment experiences, and psychopathology and suicidal ideation (SI) in a national sample of veterans deployed during the Iraq and Afghanistan conflicts (n = 2,244)...
August 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/28740430/a-systematic-literature-review-exploring-the-prevalence-of-post-traumatic-stress-disorder-and-the-role-played-by-stress-and-traumatic-stress-in-breast-cancer-diagnosis-and-trajectory
#15
REVIEW
Paola Arnaboldi, Silvia Riva, Chiara Crico, Gabriella Pravettoni
Stress has been extensively studied as a psychosomatic factor associated with breast cancer. This study aims to review the prevalence of post-traumatic stress disorder (PTSD), its associated risk factors, the role of predicting factors for its early diagnosis/prevention, the implications for co-treatment, and the potential links by which stress could impact cancer risk, by closely examining the literature on breast cancer survivors. The authors systematically reviewed studies published from 2002 to 2016 pertaining to PTSD, breast cancer and PTSD, and breast cancer and stress...
2017: Breast Cancer: Targets and Therapy
https://www.readbyqxmd.com/read/28731985/accelerated-dna-methylation-age-associations-with-ptsd-and-mortality
#16
Erika J Wolf, Mark W Logue, Tawni B Stoop, Steven A Schichman, Annjanette Stone, Naomi Sadeh, Jasmeet P Hayes, Mark W Miller
OBJECTIVE: Recently-developed indices of cellular age based on DNA methylation (DNAm) data, referred to as DNAm age, are being used to study factors that influence the rate of aging and the health correlates of these metrics of the epigenetic clock. This study evaluated associations between trauma exposure, posttraumatic stress disorder (PTSD) symptoms, and accelerated versus decelerated DNAm age among military veterans. We also examined if accelerated DNAm age predicted mortality over the course of a 6...
July 20, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28723949/post-traumatic-stress-disorder-and-other-mental-disorders-in-the-general-population-after-lorca-s-earthquakes-2011-murcia-spain-a-cross-sectional-study
#17
Fernando Navarro-Mateu, Diego Salmerón, Gemma Vilagut, Mª José Tormo, Guadalupe Ruíz-Merino, Teresa Escámez, Javier Júdez, Salvador Martínez, Karestan C Koenen, Carmen Navarro, Jordi Alonso, Ronald C Kessler
AIMS: To describe the prevalence and severity of mental disorders and to examine differences in risk among those with and without a lifetime history prior to a moderate magnitude earthquake that took place in Lorca (Murcia, Spain) at roughly the mid-point (on May 11, 2011) of the time interval in which a regional epidemiological survey was already being carried out (June 2010 -May 2012). METHODS: The PEGASUS-Murcia project is a cross-sectional face-to-face interview survey of a representative sample of non-institutionalized adults in Murcia...
2017: PloS One
https://www.readbyqxmd.com/read/28713596/discharge-against-medical-advice-in-surgical-patients-with-posttraumatic-stress-disorder-a-case-report-series-illustrating-unique-challenges
#18
Marek Brzezinski, Maren Gregersen, Luiz Gustavo Schuch, Ricarda Sawatzki, Joy W Chen, Grant Gauger, Jasleen Kukreja, Brian Cason
Discharge against medical advice (DAMA) can have detrimental effects on patient outcomes. Recently, the diagnosis of posttraumatic stress disorder (PTSD) has been linked with DAMA in the mental health setting. However, PTSD as a risk factor for DAMA in surgical patients has not received much consideration, although such patients may be at risk for triggering or amplification of PTSD symptoms perioperatively. We present the first case report series of three surgical patients with PTSD who left the hospital AMA...
2017: Case Reports in Anesthesiology
https://www.readbyqxmd.com/read/28707425/experiential-acceptance-and-trait-mindfulness-as-predictors-of-analogue-post-traumatic-stress
#19
Paul A Boelen, Lonneke I M Lenferink
OBJECTIVES: Experiential acceptance and trait-mindfulness are associated with post-traumatic stress disorder (PTSD) after traumatic events. This study was a preliminary attempt to examine (1) associations of experiential acceptance and trait-mindfulness with post-traumatic stress (PTS) associated with negative, but not necessarily traumatizing, life events ('analogue' PTS), (2) the role of these variables in the context of neuroticism as well as worry and rumination - two other regulatory strategies associated with PTS, and (3) the impact of pre-trauma tendencies towards experiential acceptance and mindfulness on analogue PTS...
July 14, 2017: Psychology and Psychotherapy
https://www.readbyqxmd.com/read/28704829/prevalence-of-and-risk-factors-for-secondary-traumatization-in-interpreters-for-refugees-a-cross-sectional-study
#20
David Kindermann, Carolin Schmid, Cassandra Derreza-Greeven, Daniel Huhn, Rupert Maria Kohl, Florian Junne, Maritta Schleyer, Judith K Daniels, Beate Ditzen, Wolfgang Herzog, Christoph Nikendei
BACKGROUND: A substantial proportion of refugees, fleeing persecution, torture, and war, are estimated to suffer from psychological traumatization. After being sheltered in reception centers, the refugees come in close contact with different occupational groups, e.g., physicians, social workers, and interpreters. Previous studies ascertained that such interpreters themselves often suffer from primary psychological traumatization. Moreover, through translating refugees' potentially traumatic depictions, the interpreters are in danger of developing a so-called secondary traumatization...
July 14, 2017: Psychopathology
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