keyword
https://read.qxmd.com/read/38508995/spontaneous-rupture-of-bladder-diverticulum-with-pseudo-renal-failure-a-case-report-and-literature-review
#1
Zhuo Zhang, Jing Shen, Qian He, Hu Nie
BACKGROUND: Spontaneous or non-traumatic bladder rupture is rare but can be life-threatening. Bladder rupture caused by a diverticulum is extremely rare, with only a few case reports in medical literature. CASE PRESENTATION: We report the case of a 32-year-old woman admitted to hospital complaints of abdominal pain, oliguria and ascites with no history of trauma. Laboratory tests revealed an elevated serum urea nitrogen(UN) level of 33.5 mmol/l and an elevated creatinine levels of 528 umol/l...
March 16, 2024: American Journal of Emergency Medicine
https://read.qxmd.com/read/38031186/can-we-predict-the-development-of-acute-gastric-dilatation-in-patients-with-anorexia-nervosa
#2
JOURNAL ARTICLE
Kristin Anderson, Ashlie Watters, Elizabeth Dee, Philip S Mehler
BACKGROUND: Acute gastric dilatation can develop in patients with anorexia nervosa who are being refed to achieve weight restoration. If unrecognized, this condition is associated with significant morbidity and mortality. Patients with acute gastric dilatation usually have abdominal pain, nausea, and vomiting. Abdominal imaging confirms the diagnosis. This study aims to identify risk factors associated with the development of acute gastric dilatation in patients with severe restrictive eating disorders in order to hasten diagnosis and guide treatment...
November 29, 2023: Journal of Eating Disorders
https://read.qxmd.com/read/38027399/is-camel-s-urine-friend-or-enemy-review-of-its-role-in-human-health-or-diseases
#3
REVIEW
Mohamed Tharwat, Tariq I Almundarij, Madeh Sadan, Faten Khorshid, Ayman Swelum
Camels play an important role in the pastoral mode of life by fulfilling basic demands of livelihood. Various pathologies, such as tuberculosis, hemorrhoids, ascites, increased size of the abdomen, gas colic, anemia, and abdominal tumors, were treated with animal urine, including camels, horses, donkeys, sheep, goats, elephants, and buffalo. Thirty different compounds were analyzed in camel urine by gas chromatography and mass spectrometry. For inductively coupled plasma mass spectrometry analysis, 28 important elements were analyzed in the urine of both camel and bovine...
October 2023: Open Veterinary Journal
https://read.qxmd.com/read/37832092/clinical-efficacy-of-dexamethasone-on-diabetic-ketoacidosis-complicated-with-acute-pancreatitis-a-randomized-controlled-study
#4
RANDOMIZED CONTROLLED TRIAL
Jing Zhang, Junfeng He
BACKGROUND: This study aimed to provide a clinical basis for the therapy of diabetic ketoacidosis (DKA) complicated with acute pancreatitis (AP) through exploring the clinical efficacy of dexamethasone. METHODS: A total of 106 DKA patients complicated with AP admitted to Wuxi People's Hospital Affiliated to Nanjing Medical University from January 2020 to December 2022 were selected and randomly divided into a study group (n = 53) and a placebo group (n = 53) according to the random number table method...
October 13, 2023: Medicine (Baltimore)
https://read.qxmd.com/read/37808385/a-study-of-socio-clinical-biochemical-and-electrocardiographic-changes-of-yellow-oleander-seed-poisoning-in-india
#5
JOURNAL ARTICLE
Murugan Subramani, Mudali Anbarasan, Shanmugam Deepalatha, Lakshmi Narayanan Muthumani, Mallu Azmeera Mahesh
Yellow oleander ( Thevetia peruviana ), which belongs to the Apocyanaceae family, is a common shrub seen throughout the tropics. All parts of the plant contain high concentrations of cardiac glycosides, which are toxic to cardiac muscle and the autonomic nervous system. The main objective of this study was to socio-clinical, biochemical and electrocardiographic changes of yellow oleander seed poisoning. This prospective observational study was conducted over a period of 6 months (March 2022 to September 2022)...
2023: Bioinformation
https://read.qxmd.com/read/37606429/review-of-the-case-reports-on-metformin-sulfonylurea-and-thiazolidinedione-therapies-in-type-2-diabetes-mellitus-patients
#6
REVIEW
Elis Susilawati, Jutti Levita, Yasmiwar Susilawati, Sri Adi Sumiwi
Type 2 diabetes mellitus (T2DM) is the world's most common metabolic disease. The development of T2DM is mainly caused by a combination of two factors: the failure of insulin secretion by the pancreatic β-cells and the inability of insulin-sensitive tissues to respond to insulin (insulin resistance); therefore, the disease is indicated by a chronic increase in blood glucose. T2DM patients can be treated with mono- or combined therapy using oral antidiabetic drugs and insulin-replaced agents; however, the medication often leads to various discomforts, such as abdominal pain, diarrhea or constipation, nausea and vomiting, and hypersensitivity reactions...
August 15, 2023: Medical Sciences: Open Access Journal
https://read.qxmd.com/read/37400005/antinociceptive-and-anti-inflammatory-activities-of-essential-oil-of-the-leaves-of-amburana-cearensis-allem%C3%A3-o-a-c-smith-from-the-semi-arid-region-of-northeastern-brazil
#7
JOURNAL ARTICLE
Bruno Oliveira de Veras, Geovanna Maria de Medeiros Moura, Amanda Vieira de Barros, Márcia Vanusa da Silva, Priscilla Anne Castro de Assis, Júlio César Ribeiro de Oliveira Farias de Aguiar, Daniela Maria do Amaral Ferraz Navarro, Rafael Matos Ximenes, Almir Gonçalves Wanderley, Maria Betânia Melo de Oliveira, Ana Catarina de Sousa Lopes
ETHNOPHARMACOLOGICAL RELEVANCE: Amburana cearensis (Allemão) A.C. Smith is a medicinal plant with wide distribution in South America, popularly known in Brazil as "cumaru" or "amburana de cheiro". In folk medicine, in the semi-arid region of Northeastern Brazil, infusions, teas and decoctions of leaves of Amburana cearensis have their practical use for treating fever, gastrointestinal disorders, inflammation, and inflammation pain. However, none of the ethnopharmacological properties has been scientifically evaluated using volatile compounds obtained from its leaves (essential oil)...
July 1, 2023: Journal of Ethnopharmacology
https://read.qxmd.com/read/37354482/clinical-spectrum-of-mercury-poisoning-in-india-case-series-from-a-poison-control-center
#8
JOURNAL ARTICLE
Amith Balachandran, Mohan Jambugulam, Krupa George, Srija Inturi, Swathi Padankatti, Anand Alwan, Sherin Susheel Mathew, Arun Jose Nellickal, Anand Zachariah, Ravikar Ralph
BACKGROUND: Mercury is a naturally occurring heavy metal that finds wide application in industrial and household settings. It exists in three chemical forms which include elemental (Hg0 ), inorganic mercurous (Hg+) or mercuric (Hg++) salts, and organic compounds. All forms are highly toxic, particularly to the nervous, gastrointestinal, and renal systems. Common circumstances of exposure include recreational substance use, suicide or homicide attempts, occupational hazards, traditional medicines, and endemic food ingestions as witnessed in the public health disasters in Minamata Bay, Japan and in Iraq...
February 2023: Journal of the Association of Physicians of India
https://read.qxmd.com/read/37336337/isolation-of-alkaloidal-and-glycosidal-fractions-from-leaves-of-trigonella-foenum-graecum-l-cv-desi-indigenous-to-pakistan-for-antiprostaglandin-evaluation-as-substitute-of-nonsteroidal-anti-inflammatory-drugs
#9
JOURNAL ARTICLE
Tahir Mahmood Shaukat, Muhammad Ovais Omer, Aqeel Javeed, Habib Ur Rehman, Tariq Mahmood Shaukat
ETHNOPHARMACOLOGICAL RELEVANCE: Trigonella foenum graecum (fenugreek) has been in use for a long time as a traditional medicine and natural food additive. The reported gastro-protective property makes it unique among other herbs. Seeds and leaves have been shown to exert significant antiatherogenic, antidiabetic, antianorexic, antioxidant, anticarcinogenic, antihyperlipidemic, galactogogue and anti-inflammatory effects in several animal and human models. But its use as a substitute for ulcerative nonsteroidal anti-inflammatory drugs needs to be confirmed...
June 17, 2023: Journal of Ethnopharmacology
https://read.qxmd.com/read/37235796/erratum-eyestalk-ablation-to-increase-ovarian-maturation-in-mud-crabs
#10
JOURNAL ARTICLE
(no author information available yet)
An erratum was issued for: Eyestalk Ablation to Increase Ovarian Maturation in Mud Crabs. The Introduction, Protocol, Discussion and References were updated. The forth sentence in the third paragraph of the Introduction has been updated from: The eyestalk ablation protocol in this work minimizes stress by using fully sedated crabs and minimizes physical injury to personnel from crab bites.  to: The eyestalk ablation protocol in this work minimizes stress by using fully anesthetized crabs and minimizes physical injury to personnel from crab bites...
May 26, 2023: Journal of Visualized Experiments: JoVE
https://read.qxmd.com/read/36707292/selective-infrared-neural-inhibition-can-be-reproduced-by-resistive-heating
#11
JOURNAL ARTICLE
Junqi Zhuo, Chloe E Weidrick, Yehe Liu, Michael A Moffitt, E Duco Jansen, Hillel J Chiel, Michael W Jenkins
OBJECTIVES: Small-diameter afferent axons carry various sensory signals that are critical for vital physiological conditions but sometimes contribute to pathologies. Infrared (IR) neural inhibition (INI) can induce selective heat block of small-diameter axons, which holds potential for translational applications such as pain management. Previous research suggested that IR-heating-induced acceleration of voltage-gated potassium channel kinetics is the mechanism for INI. Therefore, we hypothesized that other heating methods, such as resistive heating (RH) in a cuff, could reproduce the selective inhibition observed in INI...
January 25, 2023: Neuromodulation: Journal of the International Neuromodulation Society
https://read.qxmd.com/read/36225440/covid-19-vaccine-induced-rapid-progression-of-prediabetes-to-ketosis-prone-diabetes-mellitus-in-an-elderly-male
#12
Binay Kshetree, Janette Lee, Sameer Acharya
Studies show a low progression rate of prediabetes to Type 2 diabetes mellitus (DM) that we commonly seek to reverse, but we don't associate prediabetes as a lead-up to the first presentation of ketosis. We present a prediabetic who, in less than a year, converted to GAD65 antibody-positive diabetes mellitus with a diabetic ketoacidosis presentation. A 69-year-old male presented with three weeks of fatigue, polyuria, polydipsia, abdominal pain, and weight loss. Vital signs and physical exam were normal except for abdominal tenderness and dry oral mucosa...
September 2022: Curēus
https://read.qxmd.com/read/36214299/a-novel-mutation-leading-to-11-%C3%AF-hydroxylase-deficiency-in-a-female-patient
#13
Ozbas B, Demir M, Dursun H, Sahin I, Hacioglu A, Karaca Z, Dundar M, Unluhizarci K
BACKGROUND: 11β hydroxylase deficiency (11βOHD) ranks the second most common enzyme deficiency that cause congenital adrenal hyperplasia. Depending on the severity of the enzyme deficiency, it can lead to cortisol deficiency, androgen excess and hypertension due to increased mineralocorticoid precursor levels. Many different types of mutations in the CYP11B1 gene located on chromosome 8q24.3 have been shown to cause 11βOHD. Here, we report a novel missense mutation that leads to 11βOHD in a female patient...
October 7, 2022: Endocrine, Metabolic & Immune Disorders Drug Targets
https://read.qxmd.com/read/36179724/primary-aldosteronism-presenting-as-embolic-myocardial-infarction
#14
JOURNAL ARTICLE
Hye Won Lee, Yu Ji Kim, Heung Yong Jin, Kyung Ae Lee
INTRODUCTION: Primary aldosteronism is now recognized as the most common cause of secondary hypertension. Increasing evidence has demonstrated increased cardiovascular events in primary aldosteronism patients. Heart failure and atrial fibrillation are the most common cardiovascular complications occurring in these patients, and a few cases of coronary artery disease have been reported. Herein, we report a rare case of primary aldosteronism in a patient who presented with myocardial infarction associated with coronary embolism...
September 16, 2022: Neuro Endocrinology Letters
https://read.qxmd.com/read/35818960/covid-19-diagnosis-in-patients-with-acute-abdominal-pain-without-respiratory-symptoms-a-uk-emergency-general-surgical-unit-experience
#15
JOURNAL ARTICLE
Sharukh Zuberi, Yusuf Mushtaq, Krashna Patel, Saranya Vickramarajah, Alan Askari, Farhan Rashid, Roy Gurprashad
BACKGROUND: Recent evidence has emerged reporting atypical clinical symptoms of the novel coronavirus (COVID-19). There is a sparsity of existing studies examining COVID-19-related abdominal pain and the role of investigative imaging for the virus in these patients. Study aims were to determine COVID-19 incidence in those with acute abdominal pain in the absence of respiratory symptoms and to assess the diagnostic performance of CT thoracic imaging in such patients. METHODS: Retrospective analysis of all consecutive patients admitted to our emergency general surgical unit between 1st March 2020 and 31st May 2020 was performed...
July 12, 2022: American Surgeon
https://read.qxmd.com/read/35693921/a-novel-mutation-of-slc12a3-gene-causing-gitelman-syndrome
#16
Neomal De Silva, Sivatharshya Pathmanathan, Manilka Sumanatilleke, Chinthana Dematapitiya, Preethi Dissanayake, Umesha Wijenayake, Vindya Subasinghe, Vajira Dissanayake
A 48-year-old patient with a history of diabetes mellitus, presented to a surgical ward with abdominal pain. She was found to have hypokalemia. Her younger sister had passed away due to sudden cardiac death at the age of 25 years. Further evaluation revealed an elevated trans-tubular potassium gradient suggestive of renal potassium loss, normal blood pressure, hypomagnesemia, hypocalciuria, and alkalosis. Moreover, there was evidence of secondary hyperaldosteronism. Genetic studies revealed two heterozygous mutations of the SLC12A3 gene, including a novel mutation which has not been reported before anywhere in the world...
2022: SAGE Open Medical Case Reports
https://read.qxmd.com/read/35664380/documenting-disease-in-the-undocumented-migrants-a-case-report-of-chronic-kidney-disease-of-unknown-origin-in-a-central-american-migrant
#17
Adityabikram Singh, Brittany M Zaita, Isha Gupta, Gurjinder Kaur
Mesoamerican nephropathy (MeN) or chronic kidney disease of unknown origin (CKDu) is a rising epidemic in hotspot regions of El Salvador and Nicaragua. MeN is often defined in patients who exhibit a clinically reduced estimated glomerular filtration rate (eGFR) but lack a defining etiology such as diabetes or hypertension. A multitude of risk factors for MeN have been identified, including physical labor demands in a hot climate, exposure to pesticides, and poverty. Additionally, social determinants such as limited access to health care and the cost of disease burden often contribute to overall poor prognosis and progression of the disease...
April 2022: Curēus
https://read.qxmd.com/read/35386772/recurrent-seasonal-severe-hypertriglyceridemia-induced-acute-pancreatitis-a-case-report
#18
Shaho F Ahmed, Pshtiwan H Qadir, Sasan M Ahmed, Karzan M Salih, Berwn A Abdulla, Hawbash R Mohammed, Abdulwahid M Salih, Fahmi H Kakamad
Introduction: Acute pancreatitis (AP) is a serious inflammatory condition of the pancreas. Hypertriglyceridemia (HTG) is considered an uncommon cause of AP. The current study aims to present a unique case of recurrent seasonal severe HTG-induced AP (HTG-AP); treated with insulin and heparin. Case report: A 36-year-old male presented with recurrent attacks of severe upper abdominal pain that was radiating to the back and associated with repeated vomiting. The condition has being occurring every autumn-winter for the last three years...
March 2022: Annals of Medicine and Surgery
https://read.qxmd.com/read/34873512/euglycemic-diabetic-ketoacidosis-due-to-sglt2-inhibitor-in-a-patient-with-gitelman-syndrome-a-therapeutic-dilemma
#19
Taha Ahmed, Hussain Karimi, Vishwajit Hegde, Samra Haroon Lodhi
Euglycemic diabetic ketoacidosis (DKA) is a rarely reported side effect of sodium-glucose cotransporter-2 inhibitor (SGLT2i) empagliflozin. A 51-year-old female with Gitelman syndrome and type 2 diabetes mellitus (DM) presented with abdominal pain after a recent hospitalization for acute pancreatitis. Her diabetes medications included metformin, pioglitazone, and empagliflozin. Diabetic ketoacidosis was suspected; however, glucose levels were below the cutoff for DKA; therefore, she was diagnosed with euglycemic DKA...
October 2021: Curēus
https://read.qxmd.com/read/34578838/the-dietary-approach-to-the-treatment-of-the-rare-genetic-tubulopathies-gitelman-s-and-bartter-s-syndromes
#20
REVIEW
Francesco Francini, Laura Gobbi, Verdiana Ravarotto, Silvia Toniazzo, Federico Nalesso, Paolo Spinella, Lorenzo A Calò
Gitelman's (GS) and Bartter's (BS) syndromes are rare, inherited autosomal recessive tubulopathies characterized by hypokalemia, metabolic alkalosis, renal sodium, chloride, and potassium and magnesium-wasting. While the treatment based on potassium, sodium, chloride, and magnesium supplementation in addition to other pharmacologic options are widely established, recommendations about the dietary approach to GS and BS still remain generic. In this review we focus on the dietary strategies to increase sodium, potassium, and magnesium intake in GS and BS patients...
August 26, 2021: Nutrients
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