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Serous cystadenoma testis

L Olla, N Di Naro, G Puliga, G A Tolu
A case is presented of a 58-year old man with a double multilocular cystic intratesticular tumour exhibiting the morphological features described by the WHO for diagnosis of a serous papillary cystadenoma of the ovary. We classified this tumour as the male analogue of a respective ovarian growth.
February 2013: Pathologica
Guo-Xia Tong, Lorenzo Memeo, Cristina Colarossi, Diane Hamele-Bena, Cristina Magi-Galluzzi, Ming Zhou, Stephen M Lagana, Lara Harik, Jennifer M Oliver-Krasinski, Mahesh Mansukhani, Lorenzo Falcone, Hanina Hibshoosh, Kathleen O'Toole
PAX8 and PAX2 are cell-lineage-specific transcription factors that are essential for the development of Wolffian and Müllerian ducts and have recently emerged as specific diagnostic markers for tumors of renal or Müllerian origin. Little is known about their expression in the Wolffian duct-derived human male genital tract. We report our findings of PAX8 and PAX2 expression in the epithelium of the normal male genital tract and in epithelial tumors derived therefrom using immunohistochemistry (IHC). We found that PAX8 and PAX2 were expressed in the epithelium of the male genital tract from the rete testis to the ejaculatory duct...
October 2011: American Journal of Surgical Pathology
Giuseppe Albino, Rosanna Nenna, Cosimo Damiano Inchingolo, Ettore Cirillo Marucco
INTRODUCTION: Hydrocele is a fluid collection between tunica vaginalis and testis. Approximately 10% of testicular cancers occurs with a reactive hydrocele. CASE REPORT: A 64 year old male presented with a 30 year history of left hydrocele, progressively increasing. Physical examination demonstrated a left large hydrocele, transilluminable, not under pressure. Ultrasonography showed a "corpusculated hydrocele with vaginal hypertrophy jutting out near the head of the epididymis, perhaps caused by an inflammatory reaction [...
December 2010: Archivio Italiano di Urologia, Andrologia
Perikala V Kumar, Mehdi Shirazi, Mahmood Salehi
BACKGROUND: Testicular neoplasmns resembling ovarian serous tumors are rarely reported. We describe the first fine needle aspiration biopsy (FNAB) finding of this type of tumor. CASE: A 35-year-old man presented with an enlarged right testis. Based on clinical observation, we hypothesized that it was a malignant tumor. FNA cytology findings revealed numerous papillary clusters, glandular-like structures and many isolated round cells. Metastatic papillary adenocarcinoma was suspected based on FNAB cytology...
July 2009: Acta Cytologica
Sebastian C J van der Putte, Johan Toonstra, Daisy M D S Sie-Go
A 24-year-old man presented himself with a nodular lesion of about 1 cm diameter at the site of a previous orchiopexy associated with surgery for cryptorchism. Histopathology revealed the lesion to be adenomatous and confined to the scrotum. Histological and immunohistological features were not consistent neither with median raphe cysts or cutaneous adenomas nor with the intrascrotal adenomas of the rete testis, epididymis, nor with (malignant) mesotheliomas. However, the lesion did compare well with serous (papillary) cystadenomas of the testis or paratestis...
2009: Advances in Urology
Noboru Hara, Makoto Kawaguchi, Hiroshi Koike, Kota Takahashi
Median raphe cyst (MRC) is a benign lesion occurring predominantly in the ventral surface of the penises of young men and is an embryological developmental anomaly of the male genitalia. Serous borderline tumors (SBT) are found most frequently in the female ovary and only several cases with SBT of the male genitalia have been reported. We describe a case of MRC with features of SBT, which appeared in the scrotum of a 9-year-old boy after orchiopexy and was associated with surgery for cryptorchidism. The cyst arose on the right testicular tunica and consisted of cystic components with intracystic papillae lined by stratified epithelial cells, some of which showed mild cytological atypia and sporadic mitosis...
December 2004: International Journal of Urology: Official Journal of the Japanese Urological Association
F Gaytan, C Morales, M L Barreiro, P Jeffery, L K Chopin, A C Herington, F F Casanueva, E Aguilar, C Dieguez, M Tena-Sempere
Ghrelin, the endogenous ligand of the GH secretagogue receptor (GHS-R), is a newly identified, ubiquitously expressed molecule that has been involved in a wide array of endocrine and nonendocrine functions, including cell proliferation. In this context, our group recently reported the expression of ghrelin and its functional receptor, the GHS-R type 1a, in the human ovary and testis as well as several testicular tumors. Ovarian malignancies, however, remain unexplored. Notably, a vast majority of ovarian tumors derive from the surface epithelium, which originates from the celomic epithelium...
March 2005: Journal of Clinical Endocrinology and Metabolism
Evgeny Yakirevich, Edmond Sabo, Ofer Lavie, Salam Mazareb, Giulio C Spagnoli, Murray B Resnick
PURPOSE: The cancer-testis (CT) family of antigens is expressed in a variety of malignant neoplasms and is silent in normal tissues, except for the testis. Expression of two members of this family, MAGE-A4 and NY-ESO-1, has been described in melanomas, germ cell tumors, certain carcinomas and sarcomas, and more recently in uterine neoplasms. The objective of this study was to evaluate the extent and prognostic significance of CT antigen expression in ovarian serous neoplasms. EXPERIMENTAL DESIGN: Seventy-four patients with ovarian neoplasms, including 10 with serous cystadenomas, 11 with serous tumors of borderline malignancy, and 53 with serous carcinomas, were studied...
December 15, 2003: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
Thomas M Ulbright, Robert H Young
Ovarian-type surface epithelial tumors are rare in the testis and paratestis, with most reported examples being serous. There is little information on mucinous tumors, nine of which are described in this report, applying criteria and terminology used in the ovary. The patients were 44-69 years of age (median 64 years) and presented with masses in the testis (four) or paratestis (five). Eight tumors were cystic (median size, 3.5 cm) and contained gelatinous material; one (a paratesticular carcinoma) appeared as thickening of the tunica vaginalis...
September 2003: American Journal of Surgical Pathology
V Rettori, M Van Sickle, A Steinberger, R H Asch
Ovarian cystic fluid was obtained from 13 regularly cycling women with the operative diagnosis of ovarian serous (n = 6), mucinous cystadenomas (n = 3) and simple follicular cysts (n = 4). The effects of the fluids, after steroid extraction with charcoal treatment, on the binding of follicle stimulating hormone (FSH) to rat testicular homogenates and on the in vitro secretion of FSH and luteinizing hormone (LH) by rat pituitary cell preparations were studied. Similar studies were conducted simultaneously with steroid-free porcine follicular fluid (pFF)...
March 1984: Acta Europaea Fertilitatis
H Kosmehl, L Langbein, F Kiss
A case is presented of a 50-year old man with a unilocular cystic intratesticular tumour exhibiting the morphological features demanded from WHO for the diagnosis of serous papillary cystadenoma of the ovary. Keratin filaments could be demonstrated in the cyst lining and papillae covering cells by means of PAP-technique; AFP and SP-1 were lacking. The epithelial cells of the tumour showed a lectin binding pattern (WGA, UEA-I, PNA, Con A, PSA, LCA, RCA) different from the epithelium of rete testis and epididymis...
1989: International Urology and Nephrology
P Meister, E Keiditsch, B Stampfl
No abstract text is available yet for this article.
May 1990: Der Pathologe
W Remmele, E Kaiserling, U Zerban, U Hildebrand, M Bennek, P Jacobi-Nolde, F A Pinkenburg
A 59-year-old white man presented with painless scrotal swelling, a symptom he stated he had had for "several decades." Pathologic examination (conventional stainings, immunohistochemistry, and electron microscopy) revealed a cystic papillary tumor that was classified as a serous papillary cystadenoma, ovarian type, of borderline malignancy, with focal transition into invasive cancer. This appears to be the ninth reported case of testicular tumors of the serous or mucinous ovarian type and the first reported case with development of a circumscribed carcinoma from serous cystadenoma of borderline malignancy...
January 1992: Human Pathology
R W Balasa, L L Adcock, K A Prem, L P Dehner
The Brenner tumor of the ovary has been the topic of voluminous clinical and pathologic literature since its original description by Macnaughton-Jones in 1898. One of the major problems confronting most investigators of this uncommon neoplasm has been the question of histogenesis. There is general agreement that the tumor is derived from surface (coelomic) epithelium, as are the serous and mucinous cystadenomas. Most Brenner tumors are asymptomatic except for some which have features suggestive of estrogen production...
July 1977: Obstetrics and Gynecology
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