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MULTICENTER STUDY
Nirmala Bhoo-Pathy, Cuno S P M Uiterwaal, Vincent K Dik, Suzanne M Jeurnink, Bodil H Bech, Kim Overvad, Jytte Halkjær, Anne Tjønneland, Marie-Christine Boutron-Ruault, Guy Fagherazzi, Antoine Racine, Verena A Katzke, Kuanrong Li, Heiner Boeing, Anna Floegel, Anna Androulidaki, Christina Bamia, Antonia Trichopoulou, Giovanna Masala, Salvatore Panico, Paolo Crosignani, Rosario Tumino, Paolo Vineis, Petra H M Peeters, Oxana Gavrilyuk, Guri Skeie, Elisabete Weiderpass, Eric J Duell, Marcial Arguelles, Esther Molina-Montes, Carmen Navarro, Eva Ardanaz, Miren Dorronsoro, Björn Lindkvist, Peter Wallström, Malin Sund, Weimin Ye, Kay-Tee Khaw, Nick Wareham, Timothy J Key, Ruth C Travis, Talita Duarte-Salles, Heinz Freisling, Idlir Licaj, Valentina Gallo, Dominique S Michaud, Elio Riboli, H Bas Bueno-De-Mesquita
BACKGROUND & AIMS: Few modifiable risk factors have been implicated in the etiology of pancreatic cancer. There is little evidence for the effects of caffeinated coffee, decaffeinated coffee, or tea intake on risk of pancreatic cancer. We investigated the association of total coffee, caffeinated coffee, decaffeinated coffee, and tea consumption with risk of pancreatic cancer. METHODS: This study was conducted within the European Prospective Investigation into Nutrition and Cancer cohort, comprising male and female participants from 10 European countries...
November 2013: Clinical Gastroenterology and Hepatology
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MULTICENTER STUDY
Federica Turati, Carlotta Galeone, Renato Talamini, Silvia Franceschi, Marco Manzari, Gianfrancesco Gallino, Jerry Polesel, Carlo La Vecchia, Alessandra Tavani
To evaluate the association between coffee, decaffeinated coffee, and tea consumption and pancreatic cancer risk in a pooled analysis of two Italian case-control studies, between 1983 and 2008, we conducted two case-control studies in Northern Italy, including a total of 688 pancreatic cancer cases and 2204 hospital controls with acute, non-neoplastic diseases. We computed multivariate odds ratios (ORs) and 95% confidence intervals (CIs) for coffee drinking (mostly espresso and mocha), adjusting for age, sex, center, year of interview, education, body mass index, tobacco smoking, alcohol drinking, and diabetes...
July 2011: European Journal of Cancer Prevention
#3
COMPARATIVE STUDY
D S Michaud, E Giovannucci, W C Willett, G A Colditz, C S Fuchs
Although most prospective cohort studies do not support an association between coffee consumption and pancreatic cancer, the findings for alcohol are inconsistent. Recently, a large prospective cohort study of women reported statistically significant elevations in risk of pancreatic cancer for both coffee and alcoholic beverage consumption. We obtained data on coffee, alcohol, and other dietary factors using semiquantitative food frequency questionnaires administered at baseline (1986 in the Health Professionals Follow-Up Study and 1980 in the Nurses' Health Study) and in subsequent follow-up questionnaires...
May 2001: Cancer Epidemiology, Biomarkers & Prevention
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JOURNAL ARTICLE
R S Lin, I I Kessler
In the past 30 years, the incidence of pancreatic cancer has increased substantially. The disease now causes more deaths than all other malignant neoplasms, except those of the colorectal region, lung, and breast. A study in over 115 hospitals in five metropolitan areas showed that males with pancreatic cancer were more often employed in the dry cleaning business or in occupations involving close exposure to gasoline, increasing the risk for pancreatic cancer up to five times. Females at risk for pancreatic cancer were more likely to smoke cigarettes, to have uterine myomas, and to have undergone oophorectomy or spontaneous abortions...
January 9, 1981: JAMA
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JOURNAL ARTICLE
B MacMahon
The descriptive epidemiology of cancer of the pancreas is hampered by the difficulty of differential diagnosis and the variation in diagnostic expertise and resources around the world. The condition is a disease of the elderly and there are few patients under 40 years of age. The disease is somewhat more common in American blacks than in whites. Two populations of Polynesian origin--Maoris and Hawaiians--show high incidence rates, especially in males. Geographic variation is not striking and is difficult to interpret...
December 1, 1982: Cancer
#6
JOURNAL ARTICLE
E L Wynder, G S Dieck, N E Hall
The relationship between decaffeinated coffee consumption and pancreatic cancer was examined using data from a hospital-based case-control study of individuals aged 20-80 years in 18 hospitals in 6 United States cities, from January 1981 to December 1984. Among the males, 127 cases and 371 controls were examined, while for females, the figures were 111 and 325 for cases and controls, respectively. Decaffeinated coffee use was not associated with an increased risk of pancreatic cancer in males (odds ratio = 0...
October 1986: Cancer Research
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JOURNAL ARTICLE
C La Vecchia, P Liati, A Decarli, E Negri, S Franceschi
The relationship between pancreatic cancer and coffee, decaffeinated coffee and tea drinking habits was evaluated using data from a hospital-based case-control study conducted in Northern Italy on 150 histologically confirmed cases and 605 controls with acute, non-neoplastic, other than digestive tract diseases unrelated to coffee consumption or to any of the known or potential risk factors for cancer of the pancreas. Compared with subjects who did not drink coffee, the multivariate relative risks were 1.7 for those who drank less than 2 cups per day, but only 1...
September 15, 1987: International Journal of Cancer. Journal International du Cancer
#8
REVIEW
E D Gorham, C F Garland, F C Garland, A S Benenson, L Cottrell
In a study of the risk of fatal pancreatic cancer according to intake of regular and decaffeinated coffee, cases (N = 30) and controls (N = 47) were identified from death certificates and matched for age (+/- 5 years), sex, ethnicity, and date of death (+/- 5 years). Telephone interviews were completed with survivors of about 80% of both groups. In smokers, the relative risk for high (3 + cups) versus low (<3 cups) intake of regular coffee was 4.3 (P < .05), and high verus low decaffeinated coffee, 5...
January 1988: Western Journal of Medicine
#9
JOURNAL ARTICLE
J L Lyon, A W Mahoney, T K French, R Moser
Data from a population-based, case-control study of 149 cases of cancer of the exocrine pancreas (excluding insulinomas) and 363 controls were used to test the hypothesis that coffee consumption increased the risk of cancer of the exocrine pancreas. Because of the high mortality from cancer of the pancreas, all information was obtained from proxy respondents for cases and controls. Increased risk was present for coffee drinkers [odds ratio (OR) = 2.38], cigarette smokers (OR = 2.27), and alcohol users (OR = 1...
March 1992: Epidemiology
#10
JOURNAL ARTICLE
H B Bueno de Mesquita, P Maisonneuve, C J Moerman, S Runia, P Boyle
From 1984 to 1988 a population-based case-control study was carried out in the Netherlands, in collaboration with the International Agency for Research on Cancer, to examine the possible relationship between the habitual lifetime consumption of alcohol, coffee and tea and exocrine pancreatic carcinoma in 176 cases and 487 controls. An interviewer-administered questionnaire was used to ascertain major life events and obtain estimates of consumption (ever-never) and frequency of consumption throughout life. Logistic regression analyses yielded odds ratios adjusted for age, sex, response status, smoking, dietary intake of energy and vegetables and of alcoholic or non-alcoholic drinks...
February 20, 1992: International Journal of Cancer. Journal International du Cancer
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