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Siân E Halcrow, Kristina Killgrove, Gwen Robbins Schug, Michael Knapp, Damien Huffer, Bernardo Arriaza, William Jungers, Jennifer Gunter
Here we evaluate Bhattacharya et al.'s (2018) recent paper "Whole-genome sequencing of Atacama skeleton shows novel mutations linked with dysplasia" published in Genome Research. In this short report, we examine the hypothesis that the so-called "Atacama skeleton" has skeletal abnormalities indicative of dysplasia, critique the validity of the interpretations of disease based on genomic analyses, and comment on the ethics of research on this partially mummified human foetus. The current paper acts as a case study of the importance of using an anthropological approach for aDNA research on human remains...
July 16, 2018: International Journal of Paleopathology
Gregory D Roach, Thomas Kantermann, Drew Dawson, Charli Sargent, Frida Marina Fischer
The Working Time Society (WTS), and the International Commission on Occupational Health (ICOH) Scientific Committee on Shiftwork and Working Time, are twin organisations focused on conducting research, and informing practice, regarding the impact of work hours in general, and shiftwork in particular, on the efficiency, productivity, safety, well-being, health, and biological rhythms, of employees. Every 2-3 years since 1969, the WTS and ICOH have conducted a series of international symposia in Europe, Asia, Australia, North America, and South America...
June 2018: Chronobiology International
Hakan Kulaçoğlu
Guidelines are meant to evaluate the options available in the current circumstances and suggest the proper solutions for particular problems. The duty of a guideline is to present a basis for decision-making. Surgical options for the treatment of groin hernias are numerous. Recently, a joint guideline called " International Guidelines for Groin Hernia Management " was developed by five continental hernia societies, the International Endo hernia Society, and the European Association for Endoscopic Surgery...
2018: Turkish Journal of Surgery
Adeolu Oladayo Akinboro, David Adekunle Onilede, Taiwo Olabimpe Babatunde, Sebastine Oseghae Oiwoh, Oreoluwa Adeola Suleiman, Olatunde Peter Olabode
Introduction: Idiopathic scrotal calcinosis is a benign and rare disease of the scrotal skin that presents as solitary or multiple asymptomatic calcified nodules in the absence of systemic disorders of calcium/phosphorus balance. Case reports: We report the management of 2 cases and review the literature with comments on factors that determine acceptance or otherwise of surgical treatment. Our patients were 29 and 33 years old and presented with nodular scrotal lesions...
2018: Clinical, Cosmetic and Investigational Dermatology
Fredrik Hieronymus, Alexander Lisinski, Jakob Näslund, Elias Eriksson
Funded by the Danish state to provide guidance in health-related matters, the Copenhagen Trial Unit (CTU) at Rigshospitalet may cause considerable societal harm if allowing their analyses to be influenced by bias and prejudice rather than rigor and impartiality. This is why we found it worthwhile to comment on a report from the CTU in which the authors invoked analyses marred by numerous errors and methodological mistakes to claim that selective serotonin reuptake inhibitors (SSRIs) are harmful and ineffective...
July 19, 2018: Acta Neuropsychiatrica
Johanna Anneser
Palliative Sedation: Comments on a controversial topic Abstract. Palliative sedation (PS) is an accepted medical practice for terminally ill patients. It intends the alleviation of unbearable suffering by intentionally lowering the level of consciousness. In contrast to physician assisted suicide and euthanasia, palliative sedation aims to relieve burdensome symptoms with no intention of hastening death. PC can be applied as "intermittent palliative sedation" or "continuous (deep) sedation until death"...
July 2018: Therapeutische Umschau. Revue Thérapeutique
Niels Lynøe, Anders Eriksson
Since the publication of the Swedish systematic literature review on the diagnostic accuracy of the triad of signs and symptoms and shaken baby syndrome (1), several authors have commented on the arguments for classifying most previous studies as having a high risk of bias (2-4). The main reason for this classification is that scientists have used the clinical judgments of child protection teams as the reference test when classifying shaken baby cases (1). Since the diagnostic tests depend on this reference test, the outcome will be a high risk of bias (5,6)...
July 19, 2018: Acta Paediatrica
George Muller, Robert Grieshaber, J Floyd Talley, Mike Riepl, Don Fellows
The ancient autoimmune skin condition psoriasis is still ubiquitous worldwide, produces the same, often-intolerable effects noted in its earliest recorded descriptions, and remains without cure. Management options designed to resolve the itchy, scaly, weeping, erythematous, and often widespread lesions of that disorder are now available, but they vary in efficacy, most are associated with the development of severe adverse effects, and many are prohibitively expensive. In this article, we describe the successful use of a compounded formulation of oral low-dose naltrexone to manage guttate psoriasis in a 75-year-old white male patient...
July 2018: International Journal of Pharmaceutical Compounding
(no author information available yet)
On August 12, 2016, VA published in the Federal Register the proposed rule for Schedule for Rating Disabilities: Skin. VA received multiple responses during the 60-day comment period. This final rule implements the Secretary’s proposed rule with limited revisions.
July 13, 2018: Federal Register
(no author information available yet)
The Department of Veterans Affairs (VA) adopts as final, with no changes, a proposed rule amending its medical regulations related to hospital care and medical services in foreign countries. We simplified and clarified the scope of these regulations, address medical services provided to eligible veterans in the Republic of the Philippines, and removed provisions related to grants to the Republic of the Philippines that are no longer supported by statutory authority. VA also amends its medical regulations related to filing claims for reimbursement of medical expenses incurred for VA care not previously authorized...
June 25, 2018: Federal Register
Peter Lloyd-Sherlock, Fransesc Gomez-Olive, Sizzy Ngobeni, Ryan Wagner, Stephen Tollman
Background This paper describes a pilot study to assess the feasibility of a novel intervention to improve the management of hypertension among older people in rural South Africa. Older South Africans have the highest rates of uncontrolled hypertension recorded for any country. Notably, South Africa has a widely-available old age grant (pension), which is delivered on a monthly basis to citizens living in rural villages. Methods We assessed the feasibility of engaging with older people at the point of pension delivery in the Agincourt sub-district of Mpumalanga Province...
July 17, 2018: Current Aging Science
Christine Gibson, Madawa Chandratilake, Andrea Hull
Background: When the Global Health training program was created at the University of Calgary, residents were encouraged to seek learning experiences that met their career goals and individualized objectives. An assessment tool was sought that could be reliable, valid, yet flexible. A portfolio process was chosen, but research was necessary to determine whether it was robust. Methods: A qualitative study was conducted with academic experts in Canadian residency training, as well as directors and residents involved in Global Health study in order to assess the validity and benefit of such a tool...
May 2018: Canadian Medical Education Journal
Matthew Loranger, Kayla Simms, Andrew Pipe
Background: Cigarette use is Canada's leading cause of preventable disease, disability, and death. The Medical Council of Canada requires that physicians be able to address tobacco-use, however smoking cessation counselling (SCC) training remains largely neglected in the pre-clerkship curricula of many Canadian medical schools. Methods: Between July and October of 2015, Canada's 17 medical schools were invited to participate in an administrative survey: The Canadian Medical School Assessment of Smoking Cessation Counselling in the Pre-Clerkship Curriculum ...
May 2018: Canadian Medical Education Journal
Atsunobu Murase, Ryohei Miki, Masaaki Wada, Masahide Itou, Hiroyuki Motomura, Hiroshi Senou
The Potato Grouper, Epinephelus tukula , is relatively rare worldwide. Records from the northernmost part of its range (Japan) have been few, resulting in a "Critically Endangered" listing on the Red List for Japan. The Japanese records were revised by examining literature, new specimens, photographs, and the internet, and a continuous distribution pattern from the tropical Ryukyu Islands (including adult individuals) to temperate regions affected by the Kuroshio Current were delineated; this suggests the species inhabits tropical Japan and can spread to temperate regions via the warm current...
2018: ZooKeys
Peter Conrad Ng
No abstract text is available yet for this article.
June 28, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
Tuomas Eerola, Jonna K Vuoskoski, Henna-Riikka Peltola, Vesa Putkinen, Katharina Schäfer
No abstract text is available yet for this article.
July 9, 2018: Physics of Life Reviews
David Bernard, Olga Medina
The text approaches two fundamental aspects of the adolescent crisis from the works of Sigmund Freud and Gustave Flaubert: their encounter with their object in desire, pleasure, sexual act, and the causes the detachment from parental authority and their effects. A study was made on the work of Flaubert on the causes of the enigma, which the author suggests in his Memoirs of a Madman: Am I another or myself? That feeling of strangeness the adolescent experiences on waking up in a dream, with a new feeling and desire of the love object...
July 2018: Revista Colombiana de Psiquiatría
Alexandra Monkhouse, Leanne Sadler, Andrew Boyd, Fleur Kitsell
BACKGROUND: The importance of leadership development in the early stages of careers in the NHS has been highlighted in recent years and many programmes have been implemented which seek to develop leadership skills in healthcare professionals. The Improving Global Health (IGH) Fellowship scheme is one such programme, it provides a unique leadership development opportunity through an overseas placement with a focus on quality improvement work. This evaluation examines the impact of completing an IGH Fellowship on the career and leadership development of participants, who are referred to as Fellows...
July 17, 2018: Globalization and Health
(no author information available yet)
This interim final rule with comment period makes technical amendments to the regulation to reflect the extension of the transition period from June 30, 2016 to December 31, 2016 that was mandated by the 21st Century Cures Act for phasing in fee schedule adjustments for certain durable medical equipment (DME) and enteral nutrition paid in areas not subject to the Durable Medical Equipment, Prosthetics, Orthotics, and Supplies (DMEPOS) Competitive Bidding Program (CBP). In addition, this interim final rule with comment period amends the regulation to resume the transition period’s blended fee schedule rates for items furnished in rural areas and non-contiguous areas (Alaska, Hawaii, and United States territories) not subject to the CBP from June 1, 2018 through December 31, 2018...
May 11, 2018: Federal Register
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