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https://www.readbyqxmd.com/read/28793104/frailty-in-the-elderly-prevalence-and-associated-factors
#1
Jair Almeida Carneiro, Rafael Rodrigues Cardoso, Meiriellen Silva Durães, Maria Clara Araújo Guedes, Frederico Leão Santos, Fernanda Marques da Costa, Antônio Prates Caldeira
Objective: to know the prevalence and factors associated with frailty in elderly assisted by the Centro Mais Vida de Referência em Assistência à Saúde do Idoso (Mais Vida Health Reference Center for the Elderly) in the North of Minas Gerais, Brazil. Method: cross-sectional study, with sampling by convenience. Data collection occurred in 2015. Demographic and socioeconomic variables, morbidities, use of health services and the score of the Edmonton Frail Scale were analyzed...
July 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28780314/a-high-definition-video-teaching-module-for-thyroidectomy-surgery
#2
Amr F Hamour, Adrian I Mendez, Jeffrey R Harris, Vincent L Biron, Hadi Seikaly, David W J Côté
OBJECTIVE: With the changing landscape of postgraduate surgical education to competency-based curricula, there emerges a need for alternative forms of training. Video teaching modules have been shown to be effective tools in surgical education, complementing traditional postgraduate curricula. There is a lack of validated modules described in the literature, specifically for teaching thyroidectomy. The primary objective of this study was to develop and validate a high definition video-based teaching module instructing thyroidectomy surgery to Otolaryngology-Head and Neck Surgery trainees...
August 2, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28776964/a-modified-edmonton-symptom-assessment-scale-for-symptom-clusters-in-radiation-oncology-patients
#3
Peter A S Johnstone, Jae Lee, Jun-Min Zhou, Zhenjun Ma, Diane Portman, Heather Jim, Hsiang-Hsuan Michael Yu
Patient-reported outcomes regarding symptom burden may provide valuable information in addition to physician assessment. Systematic collection of patient-reported outcomes may be an important metric to identify unmet needs and improve quality of patient care. To understand common symptoms of patients seen in radiation oncology clinic, we examined the prospectively collected modified Edmonton Symptom Assessment Scale (ESAS-r) data to explore symptom clusters. Our clinic established use of a modified Edmonton Symptom Assessment Scale in August 2015...
August 4, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/28775191/feasibility-acceptability-and-diagnostic-test-accuracy-of-frailty-screening-instruments-in-community-dwelling-older-people-within-the-australian-general-practice-setting-a-study-protocol-for-a-cross-sectional-study
#4
Rachel Ambagtsheer, Renuka Visvanathan, Matteo Cesari, Solomon Yu, Mandy Archibald, Timothy Schultz, Jonathon Karnon, Alison Kitson, Justin Beilby
INTRODUCTION: Frailty is one of the most challenging aspects of population ageing due to its association with increased risk of poor health outcomes and quality of life. General practice provides an ideal setting for the prevention and management of frailty via the implementation of preventive measures such as early identification through screening. METHODS AND ANALYSIS: Our study will evaluate the feasibility, acceptability and diagnostic test accuracy of several screening instruments in diagnosing frailty among community-dwelling Australians aged 75+ years who have recently made an appointment to see their general practitioner (GP)...
August 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/28761653/individuals-with-obesity-and-type-2-diabetes-have-additional-immune-dysfunction-compared-with-obese-individuals-who-are-metabolically-healthy
#5
Caroline Richard, Michael Wadowski, Susan Goruk, Lisa Cameron, Arya M Sharma, Catherine J Field
OBJECTIVE: The objective of the current study was to compare the responses to different ex vivo immunogenic challenges between immune cells derived from metabolically healthy subjects with obesity and subjects with obesity and type 2 diabetes. RESEARCH DESIGN AND METHODS: We recruited 10 metabolically healthy subjects with obesity (Edmonton Obesity Staging System (EOSS) stage 0) and 9 subjects with obesity and type 2 diabetes (EOSS stage 2) aged between 21 years and 70 years and matched for body mass index...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28751077/validation-of-the-french-version-of-the-edmonton-symptom-assessment-system-f-esas
#6
Sophie Pautex, Petra Vayne-Bossert, Mathieu Bernard, Michel Beauverd, Boris Cantin, Claudia Mazzocato, Catherine Thollet, Catherine Bollondi-Pauly, Dominique Ducloux, François Herrmann, Monica Escher
CONTEXT: The Edmonton Symptom Assessment System is a brief, widely adopted, multidimensional questionnaire to evaluate patient-reported symptoms. OBJECTIVES: To define a standard French version of the ESAS (F-ESAS), to determine the psychometric properties in French speaking patients Methods: In a first pilot study health professionals (n: 20) and patients (n: 33) defined the most adapted terms in French (F-ESAS). In a prospective multicentric study, palliative care patients completed the three forms of F-ESAS (F-ESAS-VI; VE; NU), the Hospital Anxiety and Depression Scale (HADS)...
July 24, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28736103/what-impact-do-chaplains-have-a-pilot-study-of-spiritual-aim-for-advanced-cancer-patients-in-outpatient-palliative-care
#7
Allison Kestenbaum, Michele Shields, Jennifer James, Will Hocker, Stefana Morgan, Shweta Karve, Michael W Rabow, Laura B Dunn
CONTEXT: Spiritual care is integral to quality palliative care. Although chaplains are uniquely trained to provide spiritual care, studies evaluating chaplains' work in palliative care are scarce. OBJECTIVES: The goals of this pre-post study, conducted among patients with advanced cancer receiving outpatient palliative care, were to evaluate the feasibility and acceptability of chaplain-delivered spiritual care, utilizing the Spiritual Assessment and Intervention Model ("Spiritual AIM"); and to gather pilot data on Spiritual AIM's effects on spiritual well-being, religious and cancer-specific coping, and physical and psychological symptoms...
July 20, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28736054/low-sensitivity-of-anion-gap-to-detect-clinically-significant-lactic-acidosis-in-the-emergency-department
#8
Q Xu, S HowlettClyne, A Fuezery, G S Cembrowski
INTRODUCTION: Lactic acidosis represents the pathologic accumulation of lactate and hydrogen ions. It is important to efficiently diagnose lactic acidosis as delayed treatment will lead to poor patient outcomes. As plasma lactate levels may not be rapidly available, some physicians may use elevated anion gaps to test for the need to measure lactate. All Edmonton metropolitan hospitals have Radiometer blood gas/electrolyte instruments in the ED or close by. As lactate is measured for each set of electrolytes, we were able to determine the effectiveness of a screening anion gap for lactic acidosis...
July 20, 2017: Clinical Biochemistry
https://www.readbyqxmd.com/read/28731422/frailty-in-men-living-with-hiv-a-cross-sectional-comparison-of-three-frailty-instruments
#9
Hui-Ling Yeoh, Allen Cheng, Clovis Palmer, Suzanne M Crowe, Jennifer F Hoy
BACKGROUND: Potent antiretroviral treatment has resulted in near normal life expectancy for people living with HIV. Consequently, there is an increased focus on comorbidities, frailty and quality of life. METHODS: We assessed and compared the prevalence of frailty, associated factors and relationship with quality of life in older Australian men living with HIV in a cross-sectional study using three frailty measurements. The Frailty Phenotype, Frailty Index, and Edmonton Frail Scale were applied to 93 HIV-infected men aged over 50 years, on antiretroviral therapy...
July 21, 2017: Antiviral Therapy
https://www.readbyqxmd.com/read/28728515/the-prevalence-of-constipation-at-admission-and-after-1-week-of-palliative-care-a-multi-center-study
#10
Sebastiano Mercadante, Francesco Masedu, Marco Maltoni, Daniela De Giovanni, Luigi Montanari, Cristina Pittureri, Raffaella Bertè, Laura Ursini, Franco Marinangeli, Federica Aielli
AIM: To assess the prevalence and intensity of constipation in advanced-cancer patients referred to palliative care, and to assess changes after 1 week of specialist palliative care. METHODS: This was a prospective multi-center study in advanced patients for a period of 1 year. At admission (T0), age, gender, primary tumor, concomitant diseases, Karnofsky status, Palliative prognostic score (PaP), Edmonton Symptom Assessment scale (ESAS), Memorial Delirium Assessment Scale (MDAS), and bowel function index (BFI) were collected...
August 16, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28721290/frailty-and-elderly-in-urology-is-there-an-impact-on-post-operative-complications
#11
Fabrizio Dal Moro, Alessandro Morlacco, Giovanni Motterle, Lisa Barbieri, Filiberto Zattoni
INTRODUCTION: Frailty used as predictive tool is still not carried out in daily practice, although many studies confirm the great clinical importance of the frailty syndrome in surgical outcomes. There is no standardized method of measuring the physiological reserves of older surgical patients. The aim of this study was to analyze a cohort of older urological patients according to various frailty indices, in order to evaluate whether they are predictors of post-operative complications after urological procedures...
June 30, 2017: Central European Journal of Urology
https://www.readbyqxmd.com/read/28720558/my-team-of-care-study-a-pilot-randomized-controlled-trial-of-a-web-based-communication-tool-for-collaborative-care-in-patients-with-advanced-cancer
#12
Teja Voruganti, Eva Grunfeld, Trevor Jamieson, Allison M Kurahashi, Bhadra Lokuge, Monika K Krzyzanowska, Muhammad Mamdani, Rahim Moineddin, Amna Husain
BACKGROUND: The management of patients with complex care needs requires the expertise of health care providers from multiple settings and specialties. As such, there is a need for cross-setting, cross-disciplinary solutions that address deficits in communication and continuity of care. We have developed a Web-based tool for clinical collaboration, called Loop, which assembles the patient and care team in a virtual space for the purpose of facilitating communication around care management...
July 18, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28717768/symptom-levels-in-care-seeking-bangladeshi-and-nepalese-adults-with-advanced-cancer
#13
Richard Reed Love, Tahmina Ferdousy, Bishnu D Paudel, Shamsun Nahar, Rumana Dowla, Mohammad Adibuzzaman, Golam Mushih Tanimul Ahsan, Miftah Uddin, Reza Salim, Sheikh Iqbal Ahamed
PURPOSE: Three-fourths of patients with advanced cancer are reported to suffer from pain. A primary barrier to provision of adequate symptom treatment is failure to appreciate the intensity of the symptoms patients are experiencing. Because data on Bangladeshi and Nepalese patients' perceptions of their symptomatic status are limited, we sought such information using a cell phone questionnaire. METHODS: At tertiary care centers in Dhaka and Kathmandu, we recruited 640 and 383 adult patients, respectively, with incurable malignancy presenting for outpatient visits and instructed them for that single visit on one-time completion of a cell phone platform 15-item survey of questions about common cancer-associated symptoms and their magnitudes using Likert scales of 0 to 10...
June 2017: Journal of Global Oncology
https://www.readbyqxmd.com/read/28712662/enteropathogen-detection-in-children-with-diarrhoea-or-vomiting-or-both-comparing-rectal-flocked-swabs-with-stool-specimens-an-outpatient-cohort-study
#14
Stephen B Freedman, Jianling Xie, Alberto Nettel-Aguirre, Bonita Lee, Linda Chui, Xiao-Li Pang, Ran Zhuo, Brendon Parsons, James A Dickinson, Otto G Vanderkooi, Samina Ali, Lara Osterreicher, Karen Lowerison, Phillip I Tarr
BACKGROUND: Enteropathogen detection traditionally relies on diarrhoeal stool samples, but these are inconvenient to collect if they are not immediately available, leading to suboptimum return rates of samples and delayed or missed diagnostic opportunities. We sought to compare the enteropathogen yields of rectal swabs and stool specimens in children with diarrhoea or vomiting, or both. METHODS: The Alberta Provincial Pediatric EnTeric Infection TEam (APPETITE) did a study in three outpatient cohorts in Calgary and Edmonton (AB, Canada)-children enrolled in the Pediatric Emergency Research Canada emergency departments, children receiving routine vaccinations at a Calgary health clinic, and symptomatic children who met criteria for treatment at home...
July 13, 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28710110/impact-of-a-patient-tailored-complementary-integrative-medicine-programme-on-disturbed-sleep-quality-among-patients-undergoing-chemotherapy
#15
Hilit Kerner, Noah Samuels, Shlomi Ben Moshe, Ilanit Shalom Sharabi, Eran Ben-Arye
OBJECTIVES: The present study examined the impact of a patient-tailored complementary/integrative medicine (CIM) programme on sleep quality in patients undergoing chemotherapy for breast and gynaecological cancer. METHODS: Study participants received standard supportive care, with or without weekly CIM treatments. Disturbed sleep quality was defined as a score of ≥4 on the Edmonton Symptom Assessment Scale (ESAS) or a score of ≥3 on the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30)...
July 14, 2017: BMJ Supportive & Palliative Care
https://www.readbyqxmd.com/read/28688121/assessing-the-cost-of-implementing-the-2011-society-of-obstetricians-and-gynecologists-of-canada-and-canadian-college-of-medical-genetics-practice-guidelines-on-the-detection-of-fetal-aneuploidies
#16
Margaret Lilley, Stacey Hume, Nina Karpoff, Georges Maire, Sherry Taylor, Robert Tomaszewski, Maisa Yoshimoto, Susan Christian
BACKGROUND: The Society of Obstetricians and Gynecologists of Canada (SOGC) and the Canadian College of Medical Genetics (CCMG) published guidelines, in 2011, recommending replacement of karyotype with QF-PCR when prenatal testing is performed because of an increased risk of a common aneuploidy. STUDY OBJECTIVE: This study's objective is to perform a cost analysis following the implementation of QF-PCR as a stand-alone test. RESULTS: A total of 658 samples were received between April 1, 2014 and August 31, 2015: 576 amniocentesis samples and 82 CVS...
July 8, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28680173/venous-thromboembolism-prophylaxis-on-general-internal-medicine-units-are-patients-well-served-by-current-practice
#17
Allison Mejilla, Micheal Guirguis, Sheri Koshman, Tammy J Bungard
BACKGROUND: Venous thromboembolism (VTE) is the most preventable hospital-associated complication, and implementation of appropriate VTE prophylaxis is a requirement for institutional accreditation. However, ambiguity and controversy exist within current recommendations, and greater clarity about and understanding of current utilization of VTE prophylaxis may be needed. OBJECTIVES: The primary objective was to assess the proportion of patients receiving appropriate VTE prophylaxis (right drug, dose, frequency, and duration) within 24 h after admission to general internal medicine units...
May 2017: Canadian Journal of Hospital Pharmacy
https://www.readbyqxmd.com/read/28668143/prognosis-impact-of-frailty-assessed-by-the-edmonton-frail-scale-in-the-setting-of-acute-coronary-syndrome-in-the-elderly
#18
Stéphanie Blanco, Jean Ferrières, Vanina Bongard, Olivier Toulza, Fatia Sebai, Sophie Billet, Caroline Biendel, Olivier Lairez, Thibault Lhermusier, Nicolas Boudou, Francisco Campelo-Parada, Jérôme Roncalli, Michel Galinier, Didier Carrié, Meyer Elbaz, Frédéric Bouisset
BACKGROUND: Elderly patients represent a large proportion of patients admitted for acute coronary syndrome (ACS). Whether frailty-defined as a biological syndrome that reflects a state of decreased physiological reserve and vulnerability to stressors-may impact the clinical outcomes in this population remains unclear. We aimed to determine the prevalence of frailty and its impact on mortality in patients aged ≥ 80 years admitted for ACS. METHODS: This prospective observational study was conducted in patients aged 80 years or older admitted to a tertiary hospital for ACS...
July 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28666762/the-impact-of-baseline-edmonton-symptom-assessment-scale-scores-on-treatment-and-survival-in-patients-with-advanced-non-small-cell-lung-cancer
#19
Sharon F McGee, Tinghua Zhang, Hannah Jonker, Scott A Laurie, Glen Goss, Garth Nicholas, Khalid Albaimani, Paul Wheatley-Price
BACKGROUND: Palliative systemic therapy is frequently underutilized in patients with advanced non-small-cell lung cancer (NSCLC), for many reasons. The aim of this study was to identify patient-reported factors that may predict for treatment decisions and survival in advanced NSCLC, using the Edmonton Symptom Assessment Scale (ESAS), which is a self-reported questionnaire that quantifies symptom burden by asking patients to rate the severity of 9 common symptoms. PATIENTS AND METHODS: With ethics approval, we analyzed ESAS scores at initial oncology consultation for 461 patients with advanced NSCLC seen at The Ottawa Hospital Cancer Centre from 2009 to 2012...
June 8, 2017: Clinical Lung Cancer
https://www.readbyqxmd.com/read/28662985/building-a-tissue-based-molecular-diagnostic-system-in-heart-transplant-rejection-the-heart-molecular-microscope-diagnostic-mmdx-system
#20
Philip F Halloran, Luciano Potena, Jean-Paul Duong Van Huyen, Patrick Bruneval, Ornella Leone, Daniel H Kim, Xavier Jouven, Jeff Reeve, Alexandre Loupy
BACKGROUND: The emergence of molecular systems offers opportunities for improving the assessment of rejection in heart transplant biopsy specimens. The present study developed a microarray-based system for assessing heart transplant endomyocardial biopsy (EMB) specimens. METHODS: We analyzed 331 protocol or for-cause EMB specimens from 221 subjects in 3 centers (Edmonton, Bologna, and Paris). Unsupervised principal component analysis (PCA) and archetype analysis used rejection-associated transcripts (RATs) shown in kidney transplants to be associated with antibody-mediated rejection (ABMR) or T cell-mediated rejection (TCMR), or both...
May 29, 2017: Journal of Heart and Lung Transplantation
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