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https://www.readbyqxmd.com/read/28334697/constraint-based-stoichiometric-modelling-from-single-organisms-to-microbial-communities
#1
REVIEW
Willi Gottstein, Brett G Olivier, Frank J Bruggeman, Bas Teusink
Microbial communities are ubiquitously found in Nature and have direct implications for the environment, human health and biotechnology. The species composition and overall function of microbial communities are largely shaped by metabolic interactions such as competition for resources and cross-feeding. Although considerable scientific progress has been made towards mapping and modelling species-level metabolism, elucidating the metabolic exchanges between microorganisms and steering the community dynamics remain an enormous scientific challenge...
November 2016: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28334674/organochlorine-pesticides-in-soil-air-and-vegetation-at-and-around-a-contaminated-site-in-southwestern-china-concentration-transmission-and-risk-evaluation
#2
Yanyan Fang, Zhiqiang Nie, Qingqi Die, Yajun Tian, Feng Liu, Jie He, Qifei Huang
Remediation and management of contaminated sites have become a prevalent problem under the current situation in China. The present study was conducted to investigate the concentration, transmission, and health risk of organochlorine pesticides (OCPs) in soil, air, and vegetation at and around a typical pesticide-contaminated site located in southwestern China. Exchange flux between soil and air was calculated to investigate the transmission of OCPs. Hexachlorocyclohexane (ΣHCHs, top soil: 19.1 mg/kg d.w., air: 52...
March 1, 2017: Chemosphere
https://www.readbyqxmd.com/read/28334619/investigation-on-metal-tolerance-and-phytoremoval-activity-in-the-poplar-hybrid-clone-monviso-under-cu-spiked-water-potential-use-for-wastewater-treatment
#3
Fabrizio Pietrini, Daniela Di Baccio, Valentina Iori, Sofia Veliksar, Natalia Lemanova, Liudvika Juškaitė, Audrius Maruška, Massimo Zacchini
A serious concern for the environmental and human health is represented by the increasing copper (Cu) occurrence in agricultural soils and waters, because of the possible food contamination and bioaugmentation along the trophic chain. The request for the decontamination of different matrices with an environmentally sustainable technology as the phytoremediation should be addressed by selecting plant materials with improved pollutant tolerance and removal capability. With this purpose, plants of the hybrid poplar clone "Monviso" (Populus×generosa A...
March 20, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28331085/heterologous-packaging-signals-on-ha-but-not-na-or-ns-limit-influenza-a-virus-reassortment
#4
Maria C White, John Steel, Anice C Lowen
Influenza A virus (IAV) RNA packaging signals serve to direct the incorporation of IAV gene segments into virus particles, and this process is thought to be mediated by segment-segment interactions. These packaging signals are segment- and strain-specific, and as such, they have the potential to impact reassortment outcomes between different IAV strains. Our study aimed to quantify the impact of packaging signal mismatch on IAV reassortment using the human seasonal influenza A/Panama/2007/99 (H3N2) and pandemic influenza A/Netherlands/602/2009 (H1N1) viruses...
March 22, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28330415/novel-detection-of-placental-insufficiency-by-magnetic-resonance-imaging-in-the-nonhuman-primate
#5
Jamie O Lo, Victoria H J Roberts, Matthias C Schabel, Xiaojie Wang, Terry K Morgan, Zheng Liu, Colin Studholme, Christopher D Kroenke, Antonio E Frias
The placenta is a vital organ necessary for healthy fetal development. Placental insufficiency creates an in utero environment where the fetus is at risk of insufficient oxygen or nutrient exchange. This is primarily caused by impairment of either maternal or fetal circulation or vascular thrombosis such as placental infarction. As a result of placental dysfunction, affected fetuses may be growth restricted, neurologically impaired, and at risk of increased morbidity and mortality. In a cohort of 4 pregnant Rhesus macaques, we describe antenatal detection of naturally occurring intrauterine growth restriction (IUGR) and aberrant fetal neurodevelopment in 1 animal...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28329807/are-you-sleeping-dyadic-associations-of-support-stress-and-worries-regarding-adult-children-on-sleep
#6
Amber J Seidel, Jeremy B Yorgason, Courtney A Polenick, Steven H Zarit, Karen L Fingerman
Purpose of the study: Sleep is a key factor in maintaining positive health and well-being throughout life. Although the negative outcomes of sleep problems are becoming better understood, less is known about how intergenerational relationships might affect sleep. Thus, this investigation examines the dyadic associations of support for, stress over, and worrying about adult children on sleep quality for husbands and wives. Design and Methods: The sample included 186 heterosexual married couples drawn from the Family Exchanges Study...
January 24, 2017: Gerontologist
https://www.readbyqxmd.com/read/28328103/characterization-of-maize-chitinase-a-a-tough-allergenic-molecule
#7
Mariateresa Volpicella, Claudia Leoni, Immacolata Fanizza, Marco Distaso, Guido Leoni, Laura Farioli, Todd Naumann, Elide Pastorello, Luigi Ruggiero Ceci
BACKGROUND: Food allergies are recognized as an increasing health concern. They are caused by specific proteins called food allergens. Proteins commonly identified as food allergens tend to have one of about 30 different biochemical activities. This leads to the assumption that food allergens must have specific structural features which causes their allergenicity. But these structural features are not completely understood. Uncovering the structural basis of allergenicity would allow improved diagnosis and therapy of allergies and would provide insights for safer food production...
March 22, 2017: Allergy
https://www.readbyqxmd.com/read/28327593/characterisation-of-mental-health-conditions-in-social-media-using-informed-deep-learning
#8
George Gkotsis, Anika Oellrich, Sumithra Velupillai, Maria Liakata, Tim J P Hubbard, Richard J B Dobson, Rina Dutta
The number of people affected by mental illness is on the increase and with it the burden on health and social care use, as well as the loss of both productivity and quality-adjusted life-years. Natural language processing of electronic health records is increasingly used to study mental health conditions and risk behaviours on a large scale. However, narrative notes written by clinicians do not capture first-hand the patients' own experiences, and only record cross-sectional, professional impressions at the point of care...
March 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28327136/perceptions-of-interprofessional-collaboration-of-general-practitioners-and-community-pharmacists-a-qualitative-study
#9
Christin Löffler, Carolin Koudmani, Femke Böhmer, Susanne D Paschka, Jennifer Höck, Eva Drewelow, Martin Stremme, Bernd Stahlhacke, Attila Altiner
BACKGROUND: Despite numerous evidences for the positive effect of community pharmacists on health care, interprofessional collaboration of pharmacists and general practitioners is very often limited. Though highly trained, pharmacists remain an underutilised resource in primary health care in most western countries. This qualitative study aims at investigating pharmacists' and general practitioners' views on barriers to interprofessional collaboration in the German health care system...
March 21, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28326797/positive-and-negative-social-exchanges-experienced-by-fathers-and-mothers-of-children-with-autism
#10
Emily J Hickey, Lindsay Dubois, Sigan L Hartley
When faced with child-related challenges associated with autism spectrum disorder, positive and negative social exchanges may be critical to parents' psychological well-being. This study examined the types and sources of positive and negative social exchanges reported by mothers and fathers of children with autism spectrum disorder and their association with parental depressive symptoms in 176 families of children (5-12 years; 85% male) with autism spectrum disorder. One-way repeated measure multivariate analyses of variance and multilevel modeling were used...
March 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/28325242/radiation-oncology-in-india-challenges-and-opportunities
#11
REVIEW
Surbhi Grover, Shivakumar Gudi, Ajeet Kumar Gandhi, Priya M Puri, Adam C Olson, Danielle Rodin, Onyi Balogun, Preet K Dhillon, Daya Nand Sharma, Goura Kishor Rath, Shyam Kishore Shrivastava, Akila N Viswanathan, Umesh Mahantshetty
Rising cancer incidence and mortality in India emphasize the need to address the increasing burden of this disease and the stark inequities in access to radiotherapy and other essential medical treatments. State-of-the-art technology is available within the private sector and a few hospitals in the public sector, but 75% of patients in the public sector in India do not have access to timely radiotherapy. This inequity in access to radiotherapy in the public sector is amplified in rural areas, where most of India׳s population lives...
April 2017: Seminars in Radiation Oncology
https://www.readbyqxmd.com/read/28323474/jail-booking-as-an-occasion-for-hiv-care-reengagement-a-surveillance-based-study
#12
McKenna C Eastment, Katelynne Gardner Toren, Lara Strick, Susan E Buskin, Matthew R Golden, Julia C Dombrowski
OBJECTIVES: To examine population and HIV care outcomes of people living with HIV/AIDS (PLWHA) at their first incarceration of 2014 in 2 county jails in King County, Washington. METHODS: Using HIV surveillance data linked with jail booking data, we examined demographic information, viral loads, CD4 counts, and incarceration details for the period prior to jail booking, during incarceration, and year following jail release. RESULTS: In 2014, 202 PLWHA were incarcerated, 51% of whom were virally nonsuppressed at booking...
March 21, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28323317/the-health-insurance-gap-after-implementation-of-the-affordable-care-act-in-texas
#13
Gordon Gong, Cassandra C Huey, Coleman Johnson, Debra Curti, Billy U Philips
Households with incomes between 18% and 99% of the federal poverty level (FPL) are ineligible for Medicaid or enrollment in the health insurance exchange marketplace in Texas, resulting in the health insurance gap. We sought to determine the number of non-elderly adult Texans (NEATs) aged between 18 and 64 years in the insurance gap in rural vs urban areas in East Texas, West Texas, and South Texas. Data were obtained from the US Census Bureau website. In 2014, there were 1,101,000 NEATs in the insurance gap, accounting for 24...
March 1, 2017: Texas Medicine
https://www.readbyqxmd.com/read/28320535/optimization-of-selective-pressurized-liquid-extraction-of-organic-pollutants-in-placenta-to-evaluate-prenatal-exposure
#14
REVIEW
Tania Fernández-Cruz, Elena Martínez-Carballo, Jesús Simal-Gándara
The early exposure to organic pollutants (OPs) related to dietary habit or environmental exposure is a concern of growing interest in environmental health. When OPs enter the body, they can accumulate in fatty tissue and even travel through the bloodstream being able to cross the placenta and reach the fetus through the substance exchange between the mother and the child. Epidemiologic and clinical data affirm that these chemicals increase the risk of adverse effects during childhood. This article reviews and addresses one of the most relevant analytical methods for determining OPs in placenta...
March 8, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28319897/dialysis-membrane-enforced-microelectrode-array-measurement-of-diverse-gut-electrical-activity
#15
Naoko Iwata, Takumi Fujimura, Chiho Takai, Kei Odani, Shin Kawano, Shinsuke Nakayama
A variety of electrical activities occur depending on the functional state in each section of the gut, but the application of microelectrode array (MEA) is rather limited. We thus developed a dialysis membranes-enforced technique to investigate diverse and complex spatio-temporal electrical activity in the gut. Muscle sheets isolated from the gastrointestinal (GI) tract of mice along with a piece of dialysis membrane were woven over and under the strings to fix them to the anchor rig, and mounted on an 8×8 MEA (inter-electrode distance=150µm)...
March 16, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28319014/human-biomonitoring-science-and-policy-for-a-healthy-future-april-17-19-2016-berlin-germany
#16
Joas Anke, Gerda Schwedler, Judy Choi, Marike Kolossa-Gehring
Following the success of the 1st International Conference on Human Biomonitoring (HBM) in Berlin in 2010, the 2nd International Conference on Human Biomonitoring took place in Berlin from April 17-19, 2016 for an exchange and updates among participants on all aspects relating to HBM. Entitled "Science and Policy for a Healthy Future", the conference brought together international experts from the scientific sector, politics, authorities, industry, non-governmental organizations (NGOs), and other involved associations...
February 7, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28316330/the-microbiota-of-the-respiratory-tract-gatekeeper-to-respiratory-health
#17
REVIEW
Wing Ho Man, Wouter A A de Steenhuijsen Piters, Debby Bogaert
The respiratory tract is a complex organ system that is responsible for the exchange of oxygen and carbon dioxide. The human respiratory tract spans from the nostrils to the lung alveoli and is inhabited by niche-specific communities of bacteria. The microbiota of the respiratory tract probably acts as a gatekeeper that provides resistance to colonization by respiratory pathogens. The respiratory microbiota might also be involved in the maturation and maintenance of homeostasis of respiratory physiology and immunity...
March 20, 2017: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/28315858/how-does-culture-affect-experiential-training-feedback-in-exported-canadian-health-professional-curricula
#18
Kerry Wilbur, Rasha Mousa Bacha, Somaia Abdelaziz
Objectives: To explore feedback processes of Western-based health professional student training curricula conducted in an Arab clinical teaching setting. Methods: This qualitative study employed document analysis of in-training evaluation reports (ITERs) used by Canadian nursing, pharmacy, respiratory therapy, paramedic, dental hygiene, and pharmacy technician programs established in Qatar. Six experiential training program coordinators were interviewed between February and May 2016 to explore how national cultural differences are perceived to affect feedback processes between students and clinical supervisors...
March 17, 2017: International Journal of Medical Education
https://www.readbyqxmd.com/read/28314179/online-maternity-information-seeking-among-lesbian-bisexual-and-queer-women
#19
Emily H Ruppel, Hannah E Karpman, Carolyn E Delk, Mallory Merryman
OBJECTIVE: recent research has concluded that barriers to maternity health care exist for lesbian, bisexual, and queer women. This mixed methods study aims to understand patterns in seeking and sharing online health information for LBQ women attempting conception. DESIGN: researchers performed a qualitative content analysis of 400 discussions in lesbian-oriented Facebook groups, containing 1764 total instances of text. 400 discussions from heterosexual-oriented conception and parenting Facebook groups were examined for comparison purposes, though they will not be the focus of this analysis...
March 1, 2017: Midwifery
https://www.readbyqxmd.com/read/28306386/perceived-discrimination-among-racial-and-ethnic-minority-drug-users-and-the-association-with-health-care-utilization
#20
Courtney McKnight, Martha Shumway, Carmen L Masson, Enrique R Pouget, Ashly E Jordan, Don C Des Jarlais, James L Sorensen, David C Perlman
People who use drugs (PWUDs) are at increased risk for several medical conditions, yet they delay seeking medical care and utilize emergency departments (EDs) as their primary source of care. Limited research regarding perceived discrimination and PWUDs' use of health care services exists. This study explores the association between interpersonal and institutional racial/ethnic and drug use discrimination in health care settings and health care utilization among respondents (N = 192) recruited from methadone maintenance treatment programs (36%), HIV primary care clinics (35%), and syringe exchange programs (29%) in New York City (n = 88) and San Francisco (n = 104)...
March 17, 2017: Journal of Ethnicity in Substance Abuse
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