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Orthopaedic infection

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https://www.readbyqxmd.com/read/28208985/pattern-of-inpatient-dermatology-consultations-in-a-tertiary-care-centre-from-northern-india
#1
Abhilasha Williams, Anuradha Bhatia, Bimal Kanish, Paulina Rose Chaudhary, Clarence James Samuel
INTRODUCTION: The importance of dermatology inpatient consultation is of significant importance yet is not well documented. AIM: To retrospectively analyse the spectrum of dermatology inpatient consultations from the various departments and to document the most commonly occurring dermatological disorders from each speciality. MATERIALS AND METHODS: This study was done in an 800 bedded premier teaching hospital in Ludhiana, Punjab, North Western India...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28197990/a-chlorhexidine-releasing-epoxy-based-coating-on-titanium-implants-prevents-staphylococcus-aureus-experimental-biomaterial-associated-infection
#2
M Riool, A J Dirks, V Jaspers, L de Boer, T J Loontjens, C M van der Loos, S Florquin, I Apachitei, L N Rijk, H A Keul, S A Zaat
Prevention of biomaterial-associated infections (BAI) remains a challenging problem, in particular due to the increased risk of resistance development with the current antibiotic-based strategies. Metallic orthopaedic devices, such as non-cemented implants, are often inserted under high mechanical stress. These non-cemented implants cannot be protected by e.g. antibioticreleasing bone cement or other antimicrobial approaches, such as the use of bioactive glass. Therefore, in order to avoid abrasion during implantation procedures, we developed an antimicrobial coating with great mechanical stability for orthopaedic implants, to prevent Staphylococcus aureus BAI...
February 14, 2017: European Cells & Materials
https://www.readbyqxmd.com/read/28197703/contemporary-dual-mobility-cup-regional-and-private-register-methodology-and-results
#3
André Ferreira, Jean-Louis Prudhon, Régis Verdier, Jean-Marc Puch, Loys Descamps, Guy Dehri, Marcel Remi, Jacques H Caton
INTRODUCTION: The dual-mobility cup (DMC) was introduced in 1979. Due to lack of referenced publications, this interesting and innovating concept was ignored during close to 20 years. However, 180 studies (level III or IV) have now been published. Evidence-based medicine is based on level I studies. Over the past three decades, the role of national registries developed with the intention of surveying orthopaedic implants. In 2012, we developed, registered, and implemented a specific database for contemporary DMC...
February 14, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28196029/twelve-year-outcomes-of-an-oxinium-total-knee-replacement-compared-with-the-same-cobalt-chromium-design-an-analysis-of-17-577-prostheses-from-the-australian-orthopaedic-association-national-joint-replacement-registry
#4
Christopher J Vertullo, Peter L Lewis, Stephen Graves, Lan Kelly, Michelle Lorimer, Peter Myers
BACKGROUND: Oxidized zirconium (Oxinium) was introduced as an alternative bearing surface to cobalt-chromium (CoCr) in an attempt to reduce polyethylene wear and decrease aseptic mechanical failure of total knee replacements. While noncomparative reports have been described as promising, we were aware of no short or long-term clinical studies showing the superiority of Oxinium on polyethylene as a bearing surface. Using data from a comprehensive national joint replacement registry, we compared the long-term outcomes after cruciate-retaining total knee arthroplasty (TKA) with an Oxinium femoral component and those with the same prosthetic design but with a CoCr femoral component...
February 15, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28194715/does-extracellular-dna-production-vary-in-staphylococcal-biofilms-isolated-from-infected-implants-versus-controls
#5
Beata Zatorska, Marion Groger, Doris Moser, Magda Diab-Elschahawi, Luigi Segagni Lusignani, Elisabeth Presterl
BACKGROUND: Prosthetic implant infections caused by Staphylococcus aureus and epidermidis are major challenges for early diagnosis and treatment owing to biofilm formation on the implant surface. Extracellular DNA (eDNA) is actively excreted from bacterial cells in biofilms, contributing to biofilm stability, and may offer promise in the detection or treatment of such infections. QUESTIONS/PURPOSES: (1) Does DNA structure change during biofilm formation? (2) Are there time-dependent differences in eDNA production during biofilm formation? (3) Is there differential eDNA production between clinical and control Staphylococcal isolates? (4) Is eDNA production correlated to biofilm thickness? METHODS: We investigated eDNA presence during biofilm formation in 60 clinical and 30 control isolates of S aureus and S epidermidis...
February 13, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28192826/the-management-of-bone-defects-in-periarticular-knee-injuries-a-review-article
#6
Brian Buck, Yvonne M Murtha
Traumatic bone defects of the distal femur and proximal tibia present treatment challenges for the orthopaedic traumatologist. In addition to bone loss, significant soft tissue compromise and cartilage defects leave the patient and surgeon with few reconstructive options for proper long-term joint function. These injuries are often complicated by delayed healing, nonunion, malunion, infection, and poor subjective patient outcomes. There are a variety of clinical problems associated with the treatment of periarticular fractures about the knee...
February 13, 2017: Journal of Knee Surgery
https://www.readbyqxmd.com/read/28169937/outcomes-of-distal-femur-nonunions-treated-with-a-combined-nail-plate-construct-and-autogenous-bone-grafting
#7
Basem Attum, Diana Douleh, Paul S Whiting, Gabrielle A White-Dzuro, Ashley C Dodd, Michelle S Shen, William T Obremskey, Manish K Sethi
SummaryIn this study, we sought to retrospectively evaluate union and infection rates after treatment of distal femur nonunions using a combined nail/plate construct with autogenous bone grafting. 10 patients treated at a Level I Trauma Center for nonunion of a femoral fracture using a combined nail/plate construct from 2004 to 2014 were included in the study. Union rate and postoperative infection rate were recorded.10 patients underwent treatment for nonunion of the distal femur. Mean interval from index surgery to nonunion repair was 12 months (range 4-36 months)...
December 26, 2016: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28157079/treatment-outcomes-and-quality-of-life-after-the-implantation-of-modular-prostheses-of-the-proximal-femur-in-patients-with-cancer-metastases
#8
Grzegorz Guzik
BACKGROUND: Surgical treatment of pathological fractures of the proximal femur with intramedullary rods produces good short-term outcomes, but after some time the fixation often becomes unstable in patients with a good prognosis and a repeat surgery is required. Modular prostheses allow for better long-term outcomes. MATERIAL AND METHODS: A total of 64 surgical resection procedures for metastatic tumours of the proximal femur combined with the implantation of modular prostheses were performed at the Oncological Orthopaedics Department in Brzozów in 2010-2014...
May 5, 2016: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28154812/qivas-therapy-for-treatment-of-implant-associated-mdr-bacterial-infection
#9
Varun Chouhan
INTRODUCTION: Orthopedic implant-associated infections are difficult to treat, both physically and psychologically, for the patient and the surgeon as well. Organisms capable of forming biofilms tend to be more virulent and have ability of causing chronic infections. Chronic implant associated infections are very difficult to treat, requires a lot of time, money and other resources. Chronic infections produce a lot of morbidity and sometimes mortality to the patient. CASE REPORT: A 40-year-old male treated for bilateral acetabular fracture sustained after fall from height due to an episode of seizure...
April 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28148674/computer-hexapod-assisted-orthopaedic-surgery-provides-a-predictable-and-safe-method-of-femoral-deformity-correction
#10
A Hughes, N Heidari, S Mitchell, J Livingstone, M Jackson, R Atkins, F Monsell
AIMS: Computer hexapod assisted orthopaedic surgery (CHAOS), is a method to achieve the intra-operative correction of long bone deformities using a hexapod external fixator before definitive internal fixation with minimally invasive stabilisation techniques. The aims of this study were to determine the reliability of this method in a consecutive case series of patients undergoing femoral deformity correction, with a minimum six-month follow-up, to assess the complications and to define the ideal group of patients for whom this treatment is appropriate...
February 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28148666/custom-made-total-ankle-arthroplasty-for-the-salvage-of-major-talar-bone-loss
#11
J Wagener, C E Gross, C Schweizer, T Horn Lang, B Hintermann
AIMS: A failed total ankle arthroplasty (TAA) is often associated with much bone loss. As an alternative to arthrodesis, the surgeon may consider a custom-made talar component to compensate for the bone loss. Our aim in this study was to assess the functional and radiological outcome after the use of such a component at mid- to long-term follow-up. PATIENTS AND METHODS: A total of 12 patients (five women and seven men, mean age 53 years; 36 to77) with a failed TAA and a large talar defect underwent a revision procedure using a custom-made talar component...
February 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28148665/the-impact-of-lifestyle-risk-factors-on-the-rate-of-infection-after-surgery-for-a-fracture-of-the-ankle
#12
L L Olsen, A M Møller, S Brorson, R B Hasselager, R Sort
AIMS: Lifestyle risk factors are thought to increase the risk of infection after acute orthopaedic surgery but the evidence is scarce. We aimed to investigate whether smoking, obesity and alcohol overuse are risk factors for the development of infections after surgery for a fracture of the ankle. PATIENTS AND METHODS: We retrospectively reviewed all patients who underwent internal fixation of a fracture of the ankle between 2008 and 2013. The primary outcome was the rate of deep infection and the secondary outcome was any surgical site infection (SSI)...
February 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28148657/orthopaedic-surgical-site-infection-surveillance-in-nhs-england-national-audit-of-current-practice
#13
REVIEW
E K Tissingh, A Sudlow, A Jones, J F Nolan
AIMS: The importance of accurate identification and reporting of surgical site infection (SSI) is well recognised but poorly defined. Public Health England (PHE) mandated collection of orthopaedic SSI data in 2004. Data submission is required in one of four categories (hip prosthesis, knee prosthesis, repair of neck of femur, reduction of long bone fracture) for one quarter per year. Trusts are encouraged to carry out post-discharge surveillance but this is not mandatory. Recent papers in the orthopaedic literature have highlighted the importance of SSI surveillance and the heterogeneity of surveillance methods...
February 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28140564/mussel-inspired-multifunctional-hydrogel-coating-for-prevention-of-infections-and-enhanced-osteogenesis
#14
Hao Cheng, Kan Yue, Mehdi Kazemzadeh-Narbat, Yanhui Liu, Akbar Khalilpour, Bingyun Li, Yu Shrike Zhang, Nasim Annabi, Ali Khademhosseini
Prevention of post-surgery infection and promotion of bio-integration are the key factors to achieve long-term success in orthopaedic implants. Localized delivery of antibiotics and bioactive molecules by the implant surface serves as a promising approach towards these goals. However, previously reported methods for surface functionalization of the titanium (Ti) alloy implants to load bioactive ingredients suffer from time-consuming complex processes and lack of long-term stability. Here, we present the design and characterization of an adhesive, osteoconductive, and antimicrobial hydrogel coating for Ti implants...
January 31, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28135373/elution-profiles-of-two-methods-of-antibiotic-tibial-nail-preparations
#15
Matthew R Karek, Nancy M Jackson, Jeffrey C Flynn, Rahul Vaidya, David C Markel
Interlocking nails coated with antibiotic-supplemented cement provide effective treatment of infected long bone nonunion, but the thicker coating on guidewires may provide greater antibacterial activity. This study compared the properties of cement cured on each construct by evaluating 2-cm segments of 8-mm interlocking nails and 3.5-mm guidewires coated with antibiotic-supplemented cement. Each construct (n=7 for each group) was coated with polymethylmethacrylate cement (Simplex; Stryker Orthopaedics, Mahwah, New Jersey) containing either 1 g tobramycin or 1 g vancomycin powder plus 2...
January 30, 2017: Orthopedics
https://www.readbyqxmd.com/read/28134674/clostridium-difficile-infection-an-orthopaedic-surgeon-s-guide-to-epidemiology-management-and-prevention
#16
Paul A Anderson, James Bernatz, Nasia Safdar
Clostridium difficile infection is a growing concern in health care and is a worrisome complication in orthopaedics. The incidence and severity of this infection are increasing, although the incidence following orthopaedic surgery is comparatively lower than that seen in patients in most other surgical specialties. The typical geriatric orthopaedic patient may have many risk factors that increase the likelihood of C difficile infection, including advanced age, residence in a long-term care facility, multiple comorbidities, the use of perioperative antibiotics, and a long length of stay...
March 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28134091/irrigation-solutions-in-open-fractures-of-the-lower-extremities-evaluation-of-isotonic-saline-and-distilled-water
#17
Olukemi Temiloluwa Olufemi, Adeolu Ikechukwu Adeyeye
INTRODUCTION: Open fractures are widely considered as orthopaedic emergencies requiring immediate intervention. The initial management of these injuries usually affects the ultimate outcome because open fractures may be associated with significant morbidity. Wound irrigation forms one of the pivotal principles in the treatment of open fractures. The choice of irrigation fluid has since been a source of debate. This study aimed to evaluate and compare the effects of isotonic saline and distilled water as irrigation solutions in the management of open fractures of the lower extremities...
2017: SICOT-J
https://www.readbyqxmd.com/read/28126027/functional-analysis-of-distraction-arthroplasty-in-the-treatment-of-ankle-osteoarthritis
#18
Hongmou Zhao, Wenqing Qu, Yi Li, Xiaojun Liang, Ning Ning, Yan Zhang, Dong Hu
BACKGROUND: Ankle joint distraction arthroplasty (AJDA) is an alternative surgical procedure for the management of moderate to severe ankle osteoarthritis. However, the benefit of this procedure and failure relative factors are still in debate. The purpose of the current study was to evaluate the functional outcomes of AJDA in treatment of moderate to severe ankle OA and to evaluate the relative factors correlated with treatment failure. METHODS: Forty-six van Dijk stages II and III ankle osteoarthritis patients were included...
January 26, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28116947/type-iv-hypersensitivity-reactions-following-dermabond-adhesive-utilization-in-knee-surgery-a-report-of-three-cases
#19
Michelle Yagnatovsky, Hien Pham, Andrew Rokito, Laith Jazrawi, Eric Strauss
​We retrospectively reviewed the records of 3 patients (3 knees) with a delayed type hypersensitivity reaction following Dermabond exposure after an orthopaedic knee procedure. Delayed hypersensitivity reactions are mediated by CD4+ helper T cells. The use of skin adhesives in place of traditional sutures is increasing in popularity given Dermabond's potential benefits of decreased wound infection rate and better wound approximation. However, hypersensitivity reactions to the cyanoacrylate material in Dermabond have been described...
January 25, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/28116667/is-there-an-association-between-hemoglobin-a1c-and-deep-postoperative-infection-after-tka
#20
Jourdan M Cancienne, Brian C Werner, James A Browne
BACKGROUND: Despite substantial research into the use of glycemic markers to stratify infection risk in patients with diabetes mellitus, there is little evidence to support a perioperative hemoglobin A1c (HbA1c) level associated with an increased risk of deep postoperative infection after TKA. QUESTIONS/PURPOSES: (1) Is there an association between perioperative HbA1c level in patients with diabetes and deep postoperative infection after primary TKA? (2) Is the perioperative HbA1c level in patients with diabetes a useful test as an independent predictor for postoperative infection after TKA? METHODS: We queried the PearlDiver Patient Records Database Humana dataset for patients who underwent primary TKA...
January 23, 2017: Clinical Orthopaedics and related Research
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