keyword
MENU ▼
Read by QxMD icon Read
search

Physis

keyword
https://www.readbyqxmd.com/read/29783204/chondron-curvature-mapping-in-growth-plate-cartilage-under-compressive-loading
#1
Bhavya B Vendra, Esra Roan, John L Williams
The physis, or growth plate, is a layer of cartilage responsible for long bone growth. It is organized into reserve, proliferative and hypertrophic zones. Unlike the reserve zone where chondrocytes are randomly arranged, either singly or in pairs, the proliferative and hypertrophic chondrocytes are arranged within tubular structures called chondrons. In previous studies, the strain patterns within the compressed growth plate have been reported to be nonuniform and inhomogeneous, with an apparent random pattern in compressive strains and a localized appearance of tensile strains...
May 18, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29781506/articular-cartilage-protection-in-ctsk-mice-is-associated-with-cellular-and-molecular-changes-in-subchondral-bone-and-cartilage-matrix
#2
Fabiana N Soki, Ryu Yoshida, David N Paglia, Le T Duong, Marc F Hansen, Hicham Drissi
Osteoarthritis (OA) is a degenerative disease and a major cause of chronic disability in aging individuals. Cathepsin K (CatK), encoded by the Ctsk gene, has been implicated in the pathogenesis of pycnodysostosis and osteoporosis. The use of a selective inhibitor of CatK was recently shown to delay OA progression in rabbits. However, the cellular mechanisms underlying these protective effects remain unexplored. We examined articular cartilage maintenance and joint bone remodeling using Ctsk null mice (Ctsk-/- ) which underwent destabilization of the medial meniscus (DMM)...
May 21, 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29775757/molecular-characterization-of-physis-tissue-by-rna-sequencing
#3
Christopher R Paradise, Catalina Galeano-Garces, Daniela Galeano-Garces, Amel Dudakovic, Todd A Milbrandt, Daniel B F Saris, Aaron J Krych, Marcel Karperien, Gabriel B Ferguson, Denis Evseenko, Scott M Riester, Andre J van Wijnen, A Noelle Larson
The physis is a well-established and anatomically distinct cartilaginous structure that is crucial for normal long-bone development and growth. Abnormalities in physis function are linked to growth plate disorders and other pediatric musculoskeletal diseases. Understanding the molecular pathways operative in the physis may permit development of regenerative therapies to complement surgically-based procedures that are the current standard of care for growth plate disorders. Here, we performed next generation RNA sequencing on mRNA isolated from human physis and other skeletal tissues (e...
May 15, 2018: Gene
https://www.readbyqxmd.com/read/29735356/guaranteeing-the-quality-and-integrity-of-pork-an-australian-case-study
#4
REVIEW
H A Channon, D N D'Souza, R G Jarrett, G S H Lee, R J Watling, J Y C Jolley, F R Dunshea
The Australian pork industry is strongly committed to assuring the integrity of its product, with substantial research investment made over the past ten years to develop and implement systems to assure the consistency and quality of fresh pork and to enable accurate tracing of unpackaged fresh pork back to property of origin using trace elemental profiling. These initiatives are pivotal to allow Australian pork of guaranteed eating quality to be successfully positioned as higher value products, across a range of international and domestic markets, whilst managing any threats of product substitution...
April 27, 2018: Meat Science
https://www.readbyqxmd.com/read/29729762/editorial-commentary-the-all-epiphyseal-anterior-cruciate-ligament-distal-femoral-approach-sockets-or-tunnels
#5
EDITORIAL
Frank A Cordasco
I believe that the distal femoral approach for anterior cruciate ligament reconstruction in the skeletally immature athlete with 3 to 6 years of remaining growth is best performed with an all-inside, all-epiphyseal technique using sockets rather than an outside-in approach creating tunnels. A shorter socket rather than a longer tunnel exposes a smaller surface area of the lateral distal femoral physis to potential compromise and resultant valgus malalignment. In addition, exiting the lateral femoral aspect of the epiphysis with a full-diameter tunnel as compared with a smaller diameter drill hole used to prepare a socket places the posterior articular cartilage, the lateral collateral ligament and anterolateral ligament footprints, and the popliteus tendon insertion at risk...
May 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29682313/systematic-assessment-of-the-growth-plates-of-the-wrist-in-young-gymnasts-development-and-validation-of-the-amsterdam-mri-assessment-of-the-physis-amphys-protocol
#6
Laura S Kox, Rik B J Kraan, Kees F van Dijke, Robert Hemke, Sjoerd Jens, Milko C de Jonge, Edwin H G Oei, Frank F Smithuis, Maaike P Terra, Mario Maas
Objectives: To develop and validate a protocol for MRI assessment of the distal radial and ulnar periphyseal area in gymnasts and non-gymnasts. Methods: Twenty-four gymnasts with wrist pain, 18 asymptomatic gymnasts and 24 non-gymnastic controls (33 girls) underwent MRI of the wrist on a 3T scanner. Sequences included coronal proton density-weighted images with and without fat saturation, and three-dimensional water-selective cartilage scan and T2 Dixon series. Skeletal age was determined using hand radiographs...
2018: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/29672435/outcomes-in-early-versus-late-presentation-of-focal-fibrocartilaginous-dysplasia-affecting-the-upper-extremity-a-review-of-4-cases
#7
Grigory Gershkovich, David Kahan, Scott Kozin, Daniel Zlotolow
BACKGROUND: Focal fibrocartilaginous dysplasia (FFCD) is a rare disorder of the upper and lower extremities. In the distal ulna, a ligamentous tether emerging from the metaphysis crosses the physis and restricts growth, leading to deformity. Lesion excision before radiocapitellar subluxation has been shown to restore growth and allow remodeling. We review the outcomes of 4 patients with FFCD of the distal ulna after the occurrence of radiocapitellar incongruity. METHODS: This retrospective review examined 4 patients diagnosed with FFCD of the distal ulna from 2007 to 2015...
April 18, 2018: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/29660737/treatment-of-a-paediatric-distal-femoral-malunion-deformity
#8
Greta S Pavarotti, Randy J Boudrieau
OBJECTIVE:  The aim of this article was to describe the surgical re-alignment technique and stabilization of a distal femoral deformity in a 6-week-old, male, Foxhound. METHODS:  A healing metaphyseal fracture, resulting in a valgus deformity with internal rotation, was observed just proximal to the distal femoral physis. The deformity was treated by an opening wedge osteotomy with lateral translation and external rotation of the distal epiphysis using a guide-wire technique; a corticocancellous allograft bridged the defect, which was stabilized with a 2...
April 16, 2018: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/29611848/special-considerations-for-pediatric-patellar-instability
#9
Sean Keyes, Meghan Price, Daniel W Green, Shital N Parikh
Patellar instability in children and adolescents is a challenging subset to treat. Varied forms of instability, ranging from episodic dislocation to fixed dislocation, have been recognized. It is of utmost importance for the treating physician to recognize these different patterns of instability and their associated risk factors, as more complex patterns of instability would require more extensive surgical procedures. Medial patellofemoral ligament (MPFL) reconstruction, by itself, may not suffice or may not be appropriate for the more complex instability patterns...
March 2018: American Journal of Orthopedics
https://www.readbyqxmd.com/read/29600218/arthroscopic-fixation-of-tibial-spine-avulsion-in-skeletally-immature-the-technique
#10
Skand Sinha, Durgashankar Meena, Ananta K Naik, M Selvamari, Rajendra K Arya
Introduction: Tibial spine avulsion fracture is more frequent in children than adults. Various methods of fixation have been mentioned, but concern remains about crossing the tibial physis. We present a technique of arthroscopic fixation with non-absorbable suture. Case Report: A total of 10 skeletally immature patients with tibial spine avulsion of Meyers and McKeever Type 2 and 3 were included in the study. The knee was arthroscopically cleared of hematoma. The avulsed tibial insertion of anterior cruciate ligament was reduced and held in place with tibial guide...
November 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/29600203/isolated-spontaneous-atraumatic-avulsion-of-lesser-trochanter-of-femur-a-pathognomonic-sign-of-malignancy-in-adults-a-case-report-and-review-of-literature
#11
Prasoon Kumar, Saurabh Agarwal, Rajesh Kumar Rajnish, Vishal Kumar, Karan Jindal
Introduction: Avulsion fractures of lesser trochanter (LT) of femur are generally seen following trauma with intertrochanteric or sub trochanteric fractures. Non-traumatic fractures of LT could oc-cur due to sudden violent contraction of the iliopsoas muscle that inserts on the LT; during vigorous exercise, or sudden pull involving flexion of hip. These are seen commonly in adolescents where the physis has not fused yet. Such a scenario in an adult patient most often or not leads to a diagnosis of an underlying malignancy or metastatic lesion...
November 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/29554020/what-s-new-in-pediatric-hip
#12
Matthew R Schmitz, Todd J Blumberg, Susan E Nelson, Julieanne P Sees, Wudbhav N Sankar
BACKGROUND: Developmental dysplasia of the hip (DDH), which encompasses a wide spectrum of disease from mild dysplasia to frank dislocation, is one of the most common developmental deformities of the lower extremities and one of the leading causes of future osteoarthritis and hip arthroplasty. Legg-Calvé-Perthes disease (LCPD) results from a vascular insult to the growing femoral epiphysis, which in turn can create permanent morphologic changes to the hip joint. Slipped capital femoral epiphysis (SCFE) occurs when the proximal femoral physis fails allowing the epiphysis to displace in relation to the metaphysis...
March 17, 2018: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/29549568/cozen-s-deformity-resolved-by-guided-growth
#13
Matthew Morin, Joshua Klatt, Peter M Stevens
Proximal tibial metaphyseal fractures in children can lead to progressive and symptomatic tibial valgus. Corrective osteotomy has been abandoned, due to frequent complications, including recurrent valgus deformity. While spontaneous remodelling has been reported, this is not predictable. For children with persistent deformities, we have resorted to guided growth of the tibia. We present 19 patients who were successfully treated with guided growth, tethering the proximal medial physis. There were ten boys and nine girls, ranging in age from two to 13...
March 16, 2018: Strategies in Trauma and Limb Reconstruction
https://www.readbyqxmd.com/read/29529639/what-are-the-complications-of-allograft-reconstructions-for-sarcoma-resection-in-children-younger-than-10-years-at-long-term-followup
#14
Luis A Aponte-Tinao, Jose I Albergo, Miguel A Ayerza, D Luis Muscolo, Federico Milano Ing, German L Farfalli
BACKGROUND: Preservation of limb function after resection of malignant bone tumors in skeletally immature children is challenging. Resection of bone sarcomas and reconstruction with an allograft in patients younger than 10 years old is one reconstructive alternative. However, long-term studies analyzing late complications and limb length discrepancy at skeletal maturity are scarce; this information would be important, because growth potential is altered in these patients owing to the loss of one physis during tumor resection...
March 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29521936/quantifying-the-location-of-the-radial-nerve-in-children-for-intraoperative-use
#15
Ena Nielsen, Lindsay M Andras, David L Skaggs
BACKGROUND: In adults, a relative "safe zone" for lateral approaches to the elbow has been well described in efforts to reduce iatrogenic injury, typically a minimum of 6 cm proximal to the lateral epicondyle. To avoid iatrogenic injury to the radial nerve intraoperatively, we investigated the distance of the nerve from the distal humeral physis in children. METHODS: All patients who had axial and coronal T1-weighted magnetic resonance imagings of the humerus and elbow between 2005 and 2015 were eligible...
May 2018: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/29517625/no-difference-between-bracing-and-no-bracing-after-open-reduction-and-internal-fixation-of-tibial-plateau-fractures
#16
Aakash Chauhan, Alan Slipak, Mark C Miller, Daniel T Altman, Gregory T Altman
INTRODUCTION: The use of a postoperative brace may be beneficial after open reduction and internal fixation of tibial plateau fractures. However, bracing has potential drawbacks related to cost, fitting, wound complications, and compliance. We hypothesized that no difference will be found between patients with and without bracing after open reduction and internal fixation of tibial plateau fractures. METHODS: In this prospective, comparative trial, patients were randomized to 6 weeks of bracing or no bracing after open reduction and internal fixation of tibial plateau fractures...
March 15, 2018: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/29511703/shoulder-mri-abnormalities-in-asymptomatic-little-league-baseball-players
#17
Andrew T Pennock, Jerry Dwek, Emily Levy, Philip Stearns, John Manning, M Morgan Dennis, Amanda Davis-Juarez, Tracey Bastrom, Kenneth S Taylor
Background: Youth baseball is extremely popular in the United States, but it has been associated with shoulder pain and injury. The incidence of shoulder abnormalities in this athletic population has yet to be defined. Purpose: To examine abnormalities noted on magnetic resonance imaging (MRI) in the shoulders of asymptomatic Little League baseball players and to correlate these findings with the players' throwing history and physical examinations. Study Design: Case-control study; Level of evidence, 3...
February 2018: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29437394/physical-removal-of-anions-from-aqueous-media-by-means-of-a-macrocycle-containing-polymeric-network
#18
Xiaofan Ji, Ren-Tsung Wu, Lingliang Long, Chenxing Guo, Niveen M Khashab, Feihe Huang, Jonathan L Sessler
Reported here is a hydrogel-forming polymer network that contains a water-soluble tetracationic macrocycle. Upon immersion of this polymer network in aqueous solutions containing various inorganic and organic salts, changes in the physical properties are observed that are consistent with absorption of the constituent anions into the polymer network. This absorption is ascribed to host-guest interactions involving the tetracationic macrocyclic receptor. Removal of the anions may then be achieved by lifting the resulting hydrogels out of the aqueous phase...
February 28, 2018: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29409076/the-primary-physis
#19
James M Brian, David H Choi, Michael M Moore
The primary physis is responsible for long bone growth in children and adolescents. Injury and physiologic or metabolic stress to the primary physis present unique radiologic findings that are important for radiologists to recognize and diagnose. Appreciation of the anatomy and histology of the primary physis forms the basis for understanding the imaging findings associated with pathologic conditions affecting the primary physis. Salter-Harris injuries, physeal bars, growth arrest lines, rickets, and focal periphyseal edema zones are common conditions with recognizable radiologic presentations...
February 2018: Seminars in Musculoskeletal Radiology
https://www.readbyqxmd.com/read/29405367/influence-of-evolution-on-cam-deformity-and-its-impact-on-biomechanics-of-the-human-hip-joint
#20
REVIEW
Helen Anwander, Martin Beck, Lorenz Büchler
Anatomy and biomechanics of the human hip joint are a consequence of the evolution of permanent bipedal gait. Habitat and behaviour have an impact on hip morphology and significant differences are present even within the same biological family. The forces acting upon the hip joint are mainly a function of gravitation and strength of the muscles. Acetabular and femoral anatomy ensure an inherently stable hip with a wide range of motion. The femoral head in first human ancestors with upright gait was spherical (coxa rotunda)...
February 5, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
keyword
keyword
69977
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"