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https://www.readbyqxmd.com/read/28339606/testicular-abnormalities-in-mice-with-y-chromosome-deficiencies%C3%A2
#1
Victor A Ruthig, Torbjoern Nielsen, Jonathan M Riel, Yasuhiro Yamauchi, Egle A Ortega, Quinci Salvador, Monika A Ward
We recently investigated mice with Y chromosome gene contribution limited to two, one, or no Y chromosome genes in respect to their ability to produce haploid round spermatids and live offspring following round spermatid injection. Here we explored the normalcy of germ cells and Sertoli cells within seminiferous tubules, and the interstitial tissue of the testis in these mice. We performed quantitative analysis of spermatogenesis and interstitial tissue on Periodic acid-Schiff and hematoxylin-stained mouse testis sections...
February 7, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/28220735/sustained-reduction-in-antibiotic-consumption-in-a-south-african-public-sector-hospital-four-year-outcomes-from-the-groote-schuur-hospital-antibiotic-stewardship-program
#2
T H Boyles, V Naicker, N Rawoot, P J Raubenheimer, B Eick, M Mendelson
BACKGROUND: Overuse of antibiotics has driven global bacterial resistance to the extent that we have entered a post-antibiotic era, where infections that were once easily treatable are now becoming untreatable. Efforts to control consumption have focused on antibiotic stewardship programmes (ASPs), aimed at optimising use. OBJECTIVE: To report antibiotic consumption and cost over 4 years from a public hospital ASP in South Africa (SA). METHODS: A comprehensive ASP comprising online education, a dedicated antibiotic prescription chart and weekly dedicated ward rounds was introduced at Groote Schuur Hospital, Cape Town, in 2012...
January 30, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28198337/student-life-giving-the-best-start-in-life
#3
Doreen Crawford
How many nurses on adult wards get to kick off a medicines round with a game of hide-and-seek in a play room?
February 15, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28188136/david-oliver-is-the-ward-round-dead
#4
David Oliver
No abstract text is available yet for this article.
February 10, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28176132/checking-rounds-for-isolation-precautions-in-the-control-of-multidrug-resistant-organisms-reduction-achieved
#5
P Barbadoro, E Martini, M G Gioia, R Stoico, S Savini, E Manso, G Serafini, E Prospero, M M D'Errico
The objective of this investigation was to analyze the effectiveness of a quality improvement initiative in limiting the spread of multidrug-resistant organisms (MDROs) in the hospital setting. During the period 2011-2013, a multimodal intervention was activated at a tertiary care center in Italy. The intervention included: laboratory-based surveillance, interdisciplinary training sessions, monitoring the adoption of isolation precautions and daily supervision provided by infection control nurses, and a monthly feedback...
February 7, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28174594/preventing-involuntary-admissions-special-needs-for-distinct-patient-groups
#6
Knut Hoffmann, I S Haussleiter, F Illes, J Jendreyschak, A Diehl, B Emons, C Armgart, A Schramm, G Juckel
BACKGROUND: Coercive measures in psychiatry are a controversial topic and raise ethical, legal and clinical issues. Involuntary admission of patients is a long-lasting problem and indicates a problematic pathway to care situations within the community, largely because personal freedom is fundamentally covered by the UN declaration of human rights and the German constitution. METHODS: In this study, a survey on a large and comprehensive population of psychiatric in-patients in the eastern part of North Rhine-Westphalia, Germany, was carried out for the years 2004-2009, including 230...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/28170431/bedside-or-not-bedside-evaluation-of-patient-satisfaction-in-intensive-medical-rehabilitation-wards
#7
Christophe Luthy, Patricia Francis Gerstel, Angela Pugliesi, Valérie Piguet, Anne-Françoise Allaz, Christine Cedraschi
BACKGROUND: Concerns that bedside presentation (BsP) rounds could make patients uncomfortable led many residency programs to move daily rounds outside the patients' room (OsPR). We performed a prospective quasi-experimental controlled study measuring the effect of these two approaches on patient satisfaction. METHODS: Patient satisfaction was measured using the Picker questionnaire (PiQ). Results are expressed in problematic percentage scores scaled from 0 = best-100 = worst...
2017: PloS One
https://www.readbyqxmd.com/read/28166787/the-efficacy-of-protected-mealtimes-in-hospitalised-patients-a-stepped-wedge-cluster-randomised-controlled-trial
#8
Judi Porter, Terry P Haines, Helen Truby
BACKGROUND: Protected Mealtimes is an intervention developed to address the problem of malnutrition in hospitalised patients through increasing positive interruptions (such as feeding assistance) whilst minimising unnecessary interruptions (including ward rounds and diagnostic procedures) during mealtimes. This clinical trial aimed to measure the effect of implementing Protected Mealtimes on the energy and protein intake of patients admitted to the subacute setting. METHODS: A prospective, stepped wedge cluster randomised controlled trial was undertaken across three hospital sites at one health network in Melbourne, Australia...
February 7, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28166587/teaching-rounds-a-visual-aid-to-teaching-internal-medicine-pearls-on-the-wards-first-edition
#9
Timothy Mott
No abstract text is available yet for this article.
January 2017: Family Medicine
https://www.readbyqxmd.com/read/28164385/learning-to-prescribe-through-co-working-junior-doctors-pharmacists-and-consultants
#10
Christy Noble, Stephen Billett
CONTEXT: Learning to prescribe is challenging for junior doctors. Significant efforts have been made to improve prescribing education, especially in view of the high rates of prescribing errors made by junior doctors. However, considerations of educational options often overlook the fact that learning to prescribe and prescribing practices rely on practice-based interactions with informed practitioners, such as pharmacists and consultants. Pharmacists have long made important contributions to developing prescribing capacities...
February 6, 2017: Medical Education
https://www.readbyqxmd.com/read/28138385/prospective-surveillance-of-healthcare-associated-infections-in-a-cambodian-pediatric-hospital
#11
Pasco Hearn, Thyl Miliya, Soklin Seng, Chanpheaktra Ngoun, Nicholas P J Day, Yoel Lubell, Claudia Turner, Paul Turner
BACKGROUND: Healthcare associated infections (HAI) are the most common preventable adverse events following admission to healthcare facilities. Data from low-income countries are scarce. We sought to prospectively define HAI incidence at Angkor Hospital for Children (AHC), a Cambodian pediatric referral hospital. METHODS: Prospective HAI surveillance was introduced for medical admissions to AHC. Cases were identified on daily ward rounds and confirmed using locally adapted Centers for Disease Control and Prevention (CDC) definitions...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/28103162/indicators-of-prognosis-for-admissions-from-a-specialist-diabetic-foot-clinic-a-retrospective-service-improvement-exercise
#12
Z Essackjee, C Gooday, I Nunney, K Dhatariya
OBJECTIVE: To look at haematological and biochemical variables as predictors of outcomes in people admitted to hospital with a diabetic foot ulcer (DFU) without the use of technology or devices. In particular, to see if there was a relationship between admission blood cell and protein levels, and the likelihood of angioplasty, amputation, and death at one year after admission. METHOD: A five-year retrospective analysis of patients admitted to a tertiary multidisciplinary specialist diabetic foot clinic looking at admission C-reactive protein (CRP), white cell count (WCC), neutrophil count and HbA1c and their relationship to likelihood of angioplasty, minor or major amputation, and death at one year after admission...
January 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28087887/evaluation-of-a-standardized-ward-round-in-a-prenatal-inpatient-setting
#13
Katie Christensen, Sarah Janssens, Michael Beckmann
OBJECTIVE: To evaluate the impact of incorporating a standardized ward round (SWR) tool including checklists for communication, safety, and efficiency into ward rounds. METHODS: A prospective non-randomized, before-and-after observational study was conducted at a tertiary maternity hospital in Brisbane, Australia, between October 1, 2014, and October 1, 2015. Obstetric team members performing prenatal ward rounds used role-specific lanyards prompting the structure of each consultation...
March 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28069627/what-aspects-of-intentional-rounding-work-in-hospital-wards-for-whom-and-in-what-circumstances-a-realist-evaluation-protocol
#14
Ruth Harris, Sarah Sims, Ros Levenson, Stephen Gourlay, Fiona Ross Cbe, Nigel Davies, Sally Brearley, Giampiero Favato, Robert Grant
INTRODUCTION: Intentional rounding (IR) is a structured process whereby nurses in hospitals carry out regular checks, usually hourly, with individual patients using a standardised protocol to address issues of positioning, pain, personal needs and placement of items. The widespread implementation of IR across the UK has been driven by the recommendations of the Francis Inquiry although empirical evidence of its effectiveness is poor. This paper presents a protocol of a multimethod study using a realist evaluation approach to investigate the impact and effectiveness of IR in hospital wards on the organisation, delivery and experience of care from the perspective of patients, their family members and staff...
January 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28067559/implementing-an-electronic-patient-handover-system
#15
Ben Oakley, James B Hunter
BACKGROUND: Clear communication among health-care teams is paramount for safe patient care and effective handover. Advances in information technology have led to an increased use of electronic systems within modern health care. This quality improvement project introduced an electronic patient handover system that was intended to improve the accuracy of patient handover lists and be readily available to all members of the health-care team. METHODS: A quality improvement project was undertaken to assess the effect of introducing an electronic patient handover system on maintenance workload and list accuracy...
January 2, 2017: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/28063383/push-pull-strategy-in-the-regulation-of-postembryonic-root-development
#16
REVIEW
Goh Choe, Ji-Young Lee
Unlike animals, plants continue to grow throughout their lives. The stem cell niche, protected in meristems of shoots and roots, enables this process. In the root, stem cells produce precursors for highly organized cell types via asymmetric cell divisions. These precursors, which are "transit-amplifying cells," actively divide for several rounds before entering into differentiation programs. In this review, we highlight positive feedback regulation between shoot- and root-ward signals during the postembryonic root growth, which is reminiscent of a "push-pull strategy" in business parlance...
January 4, 2017: Current Opinion in Plant Biology
https://www.readbyqxmd.com/read/28052996/novel-bioengineered-three-dimensional-human-intestinal-model-for-long-term-infection-of-cryptosporidium-parvum
#17
Maria A DeCicco RePass, Ying Chen, Yinan Lin, Wenda Zhou, David L Kaplan, Honorine D Ward
Cryptosporidium spp. are apicomplexan parasites of global importance that cause human diarrheal disease. In vitro culture models that may be used to study this parasite and that have physiological relevance to in vivo infection remain suboptimal. Thus, the pathogenesis of cryptosporidiosis remains poorly characterized, and interventions for the disease are limited. In this study, we evaluated the potential of a novel bioengineered three-dimensional (3D) human intestinal tissue model (which we developed previously) to support long-term infection by Cryptosporidium parvum Infection was assessed by immunofluorescence assays and confocal and scanning electron microscopy and quantified by quantitative reverse transcription-PCR...
March 2017: Infection and Immunity
https://www.readbyqxmd.com/read/28049889/importance-of-pharmaceutical-training-and-clinical-research-at-medical-facilities
#18
Michiaki Myotoku
 To respond to advancements in medical techniques, and to address the separation of medical and dispensary practices, clinical professors are required to educate human resource staff to become highly-skilled pharmacists. For this purpose, it is extremely important for these professors to learn about cutting-edge practical skills and knowledge, as well as to advance their expertise. In addition, they need to conduct clinical research in cooperation with relevant facilities. As our university does not have its own hospital or pharmacy, it is important to provide training for clinical professors in clinical facilities...
2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28004239/impact-of-team-versus-ward-aligned-clinical-pharmacy-on-unintentional-medication-discrepancies-at-admission
#19
Sharon M Byrne, Tamasine C Grimes, Marie-Claire Jago-Byrne, Mairéad Galvin
Background Medication reconciliation at admission to hospital reduces the prevalence of medication errors. Strategies are needed to ensure timely and efficient delivery of this service. Objective To investigate the effect of aligning clinical pharmacy services with consultant teams, by pharmacists attending post-admission ward rounds, in comparison to a ward-based service, on prevalence of unintentional unresolved discrepancies 48 h into admission. Setting A 243-bed public university teaching hospital in Ireland...
February 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/27981600/the-effect-of-pharmacists-on-ward-rounds-measured-by-the-stopp-start-tool-in-a-specialized-geriatric-unit
#20
K Mulvogue, J A Roberts, I Coombes, N Cottrell, S Kanagarajah, A Smith
WHAT IS KNOWN AND OBJECTIVE: The STOPP/START tool has been validated to assess elderly patients for potentially inappropriate prescribing. This study aimed to assess the effect of inclusion of a pharmacist on a physician-led ward round on potentially inappropriate prescribing in hospitalized elderly patients. METHODS: This was an observational study of prescribing for patients using the STOPP/START tool at three points during hospital stay; admission to hospital, on transfer to the specialized geriatric unit and on discharge from hospital...
December 16, 2016: Journal of Clinical Pharmacy and Therapeutics
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