Miriam Kessi, Fangling Yan, Langui Pan, Baiyu Chen, Eleonore Olatoutou, Dong Li, Fang He, Tibera Rugambwa, Lifen Yang, Jing Peng, Fei Yin
Background and Purpose: To date, there is no specific treatment guideline for the benign childhood epilepsy with centrotemporal spikes (BECTS). Several countries recommend levetiracetam, carbamazepine, sodium valproate, oxcarbazepine, and lamotrigine as first-line drugs. Nevertheless, some of these drugs are associated with cognitive decline. Available studies that investigated the efficacy of levetiracetam and sodium valproate on BECTS involved small sample sizes. This study aimed to evaluate the efficacy of levetiracetam and sodium valproate on cognition, and to investigate the prognostic factors for BECTS as whole...
2021: Frontiers in Neurology