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https://www.readbyqxmd.com/read/25312594/clevidipine-a-review-of-its-use-for-managing-blood-pressure-in-perioperative-and-intensive-care-settings
#1
REVIEW
Gillian M Keating
The ultrashort-acting dihydropyridine calcium channel antagonist clevidipine (Cleviprex(®)) has a rapid onset and offset of effect and reduces blood pressure (BP) by decreasing arteriolar resistance without affecting venous capacitance vessels. This article reviews the clinical efficacy and tolerability of intravenous clevidipine when used to manage BP in perioperative and intensive care settings, as well as summarizing its pharmacological properties. Intravenous clevidipine effectively treated preoperative and postoperative hypertension in patients undergoing cardiac surgery, according to the results of the randomized, multicentre, double-blind, phase III ESCAPE-1 and ESCAPE-2 trials...
October 2014: Drugs
https://www.readbyqxmd.com/read/20879629/use-of-clevidipine-for-intraoperative-hypertension-caused-by-an-undiagnosed-pheochromocytoma-a-case-report
#2
Jonathan P Kline
The acute intraoperative hypertension and tachycardia caused by an undiagnosed pheochromocytoma is a rare event for the anesthesia provider. If treatment is not prompt and successful, permanent and possibly lethal complications can ensue. This article reports what the author believes to be the first case study in which clevidipine (Cleviprex) was successfully used to treat a suspected, and later diagnosed, pheochromocytoma.
August 2010: AANA Journal
https://www.readbyqxmd.com/read/20730061/role-of-clevidipine-butyrate-in-the-treatment-of-acute-hypertension-in-the-critical-care-setting-a-review
#3
REVIEW
Ahmed S Awad, Michael E Goldberg
Acutely elevated blood pressure in the critical care setting is associated with a higher risk of acute end-organ damage (eg, myocardial ischemia, stroke, and renal failure) and perioperative bleeding. Urgent treatment and careful blood pressure control are crucial to prevent significant morbidity. Clevidipine butyrate (Cleviprex) is an ultrashort-acting, third-generation intravenous calcium channel blocker. It is an arterial-selective vasodilator with no venodilatory or myocardial depressive effects. Clevidipine has an extremely short half-life of approximately 1 minute as it is rapidly metabolized by blood and tissue esterases...
2010: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/19331440/clevidipine-a-review-of-its-use-in-the-management-of-acute-hypertension
#4
REVIEW
Emma D Deeks, Gillian M Keating, Susan J Keam
UNLABELLED: Clevidipine (Cleviprex), a late-generation dihydropyridine calcium channel antagonist available as a lipid emulsion for intravenous infusion, is approved in the US for the reduction of blood pressure (BP) when oral therapy is not feasible or desirable. Intravenous clevidipine is effective in the treatment of both acute preoperative and postoperative hypertension in adult cardiac surgery patients, and with a rapid onset and short duration of action the drug can be easily titrated for predictable BP control...
2009: American Journal of Cardiovascular Drugs: Drugs, Devices, and Other Interventions
https://www.readbyqxmd.com/read/18800023/clevidipine-cleviprex-for-iv-treatment-of-severe-hypertension
#5
(no author information available yet)
No abstract text is available yet for this article.
September 22, 2008: Medical Letter on Drugs and Therapeutics
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