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https://www.readbyqxmd.com/read/28934773/leptospirosis-in-three-workers-on-a-dairy-farm-with-unvaccinated-cattle
#1
Jackie Benschop, Julie Collins-Emerson, Allie Maskill, Patrick O'Connor, Margaret Tunbridge, Yuni Yupiana, Jenny Weston
AIM: We report a one-health investigation of three cases of leptospirosis on a dairy farm with unvaccinated cattle in New Zealand. The cases are discussed in the context of diagnostics, risk factors, persistence of symptoms and outbreak mitigation measures. METHOD: Clinical and laboratory records from the human cases were reviewed and serological and molecular investigations were conducted into the Leptospira status of cattle and pigs on the farm. RESULTS: Cases presented early in their illness and all three were confirmed within seven days of onset of symptoms by urine PCR and within 18 days by convalescent MAT (two Hardjo-bovis, one Pomona)...
September 22, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/28934712/biotransformation-of-flubendazole-and-fenbendazole-and-their-effects-in-the-ribwort-plantain-plantago-lanceolata
#2
Lucie Raisová Stuchlíková, Lenka Skálová, Barbora Szotáková, Eliška Syslová, Ivan Vokřál, Tomáš Vaněk, Radka Podlipná
Although veterinary anthelmintics represent an important source of environmental pollution, the fate of anthelmintics and their effects in plants has not yet been studied sufficiently. The aim of our work was to identify metabolic pathways of the two benzimidazole anthelmintics fenbendazole (FBZ) and flubendazole (FLU) in the ribwort plantain (Plantago lanceolata L.). Plants cultivated as in vitro regenerants were used for this purpose. The effects of anthelmintics and their biotransformation products on plant oxidative stress parameters were also studied...
September 18, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28934348/antimicrobial-resistance-in-clinical-escherichia-coli-isolates-from-poultry-and-livestock-china
#3
Afrah Kamal Yassin, Jiansen Gong, Patrick Kelly, Guangwu Lu, Luca Guardabassi, Lanjing Wei, Xiangan Han, Haixiang Qiu, Stuart Price, Darong Cheng, Chengming Wang
Poultry and livestock are the most important reservoirs for pathogenic Escherichia coli and use of antimicrobials in animal farming is considered the most important factor promoting the emergence, selection and dissemination of antimicrobial-resistant microorganisms. The aim of our study was to investigate antimicrobial resistance in E. coli isolated from food animals in Jiangsu, China. The disc diffusion method was used to determine susceptibility to 18 antimicrobial agents in 862 clinical isolates collected from chickens, ducks, pigs, and cows between 2004 and 2012...
2017: PloS One
https://www.readbyqxmd.com/read/28934242/twelve-years-of-chiari-like-malformation-and-syringomyelia-scanning-in-cavalier-king-charles-spaniels-in-the-netherlands-towards-a-more-precise-phenotype
#4
Katrien Wijnrocx, Leonie W L Van Bruggen, Wieteke Eggelmeijer, Erik Noorman, Arnold Jacques, Nadine Buys, Steven Janssens, Paul J J Mandigers
Chiari-like malformation (CM), syringomyelia (SM) and middle ear effusion (also called PSOM) are three conditions that frequently occur in Cavalier King Charles Spaniels (CKCS). Both CM and SM are currently screened in the Netherlands prior to breeding and are graded according to the British Veterinary Association's Kennel Club (BVA/KC) scheme. This study evaluated the prevalence and estimated genetic parameter of CM, SM and middle ear effusion from 12 years of screening results. For SM, the classical method using the BVA/KC scheme, was compared with exact measuring of the central canal dilation...
2017: PloS One
https://www.readbyqxmd.com/read/28933730/veterinary-pharmaceutics-an-opportunity-for-interprofessional-education-in-new-zealand
#5
Arlene McDowell, Rebekah Beard, Anna Brightmore, Lisa W Lu, Amelia McKay, Maadhuri Mistry, Kate Owen, Emma Swan, Jessica Young
Globally pharmacists are becoming increasingly involved in veterinary medicine; however, little is known about the level of interest for pharmacists playing a larger role in animal treatment in New Zealand. A key stakeholder in any progression of pharmacists becoming more involved in the practice of veterinary pharmacy is the veterinary profession. The aim of this study was to investigate views of veterinarians and veterinary students on the role of pharmacists supporting veterinarians with advice on animal medicines...
July 26, 2017: Pharmaceutics
https://www.readbyqxmd.com/read/28933680/prevalence-of-antibodies-against-hepatitis-e-virus-in-veterinarians-in-estonia
#6
Brian Lassen, Marilin Janson, Kädi Neare, Tatjana Tallo, Irina Reshetnjak, Tatiana Kuznetsova, Arvo Viltrop, Irina Golovljova, Pikka Jokelainen
In this cross-sectional study, we investigated veterinarians in Estonia for evidence of exposure to hepatitis E virus (HEV). In 2012, we collected sera from 158 persons attending a veterinary conference, of whom 156 completed a questionnaire covering their background information. Altogether 115 persons reported they had obtained a veterinary degree and were included in this study. The sera were tested for presence of antibodies against HEV using a commercial enzyme linked immunosorbent assay and a commercial immunoblot assay in series...
September 21, 2017: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/28933508/-skills-lab-training-in-veterinary-medicine-effective-preparation-for-clinical-work-at-the-small-animal-clinic-of-the-university-for-veterinary-medicine-hannover-foundation-effektive-vorbereitung-auf-die-klinische-t%C3%A3-tigkeit-am-beispiel-der-kleintierklinik
#7
Simon Engelskirchen, Jan Ehlers, Ansgar T Kirk, Andrea Tipold, Marc Dilly
OBJECTIVE: During five and a half years of studying veterinary medicine, students should in addition to theoretical knowledge acquire sufficient practical skills. Considering animal welfare and ethical aspects, opportunities for hands-on learning on living animals are limited because of the high annual number of students. The first German veterinary clinical-skills lab, established in 2013 at the University for Veterinary Medicine Hannover, Foundation (TiHo), offers opportunities for all students to learn, train and repeat clinical skills on simulators and models as frequently as they would like, until they feel sufficiently confident to transfer these skills to living animals...
September 20, 2017: Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
https://www.readbyqxmd.com/read/28932406/large-scale-survey-to-estimate-the-prevalence-of-disorders-for-192-kennel-club-registered-breeds
#8
B M Wiles, A M Llewellyn-Zaidi, K M Evans, D G O'Neill, T W Lewis
BACKGROUND: Pedigree or purebred dogs are often stated to have high prevalence of disorders which are commonly assumed to be a consequence of inbreeding and selection for exaggerated features. However, few studies empirically report and rank the prevalence of disorders across breeds although such data are of critical importance in the prioritisation of multiple health concerns, and to provide a baseline against which to explore changes over time. This paper reports an owner survey that gathered disorder information on Kennel Club registered pedigree dogs, regardless of whether these disorders received veterinary care...
2017: Canine Genetics and Epidemiology
https://www.readbyqxmd.com/read/28932389/challenges-facing-the-veterinary-profession-in-ireland-2-on-farm-use-of-veterinary-antimicrobials
#9
Manuel Magalhães-Sant'Ana, Simon J More, David B Morton, Alison J Hanlon
BACKGROUND: Antimicrobial resistance has emerged in recent years as a significant public health threat, which requires both an ethical and a scientific approach. In a recent Policy Delphi study, on-farm use of antimicrobials was a key concern identified by veterinary professionals in Ireland. In this case study (the second in a series of three resulting from a research workshop exploring the challenges facing the veterinary profession in Ireland; the other two case studies investigate clinical veterinary services and emergency/casualty slaughter certification) we aim to provide a value-based reflection on the constraints and possible opportunities for responsible use of veterinary antimicrobials in Ireland...
2017: Irish Veterinary Journal
https://www.readbyqxmd.com/read/28932221/diversity-of-vibrio-navarrensis-revealed-by-genomic-comparison-veterinary-isolates-are-related-to-strains-associated-with-human-illness-and-sewage-isolates-while-seawater-strains-are-more-distant
#10
Keike Schwartz, Cindy Kukuc, Nadja Bier, Karin Taureck, Jens A Hammerl, Eckhard Strauch
Strains of Vibrio navarrensis are present in aquatic environments like seawater, rivers, and sewage. Recently, strains of this species were identified in human clinical specimens. In this study, V. navarrensis strains isolated from livestock in Germany were characterized that were found in aborted fetuses and/or placentas after miscarriages. The veterinary strains were analyzed using phenotypical and genotypical methods and compared to isolates from marine environments of the Baltic Sea and North Sea. The investigated phenotypical traits were similar in all German strains...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28931425/neutralizing-immune-responses-induced-by-oligomeric-h5n1-hemagglutinins-from-plants
#11
Hoang Trong Phan, Thuong Thi Ho, Ha Hoang Chu, Trang Huyen Vu, Ulrike Gresch, Udo Conrad
Plant-based transient expression is an alternative platform to produce hemagglutinin-based subunit vaccines. This production system provides not only fast and effective response in the context of a pandemic but also enables the supply of big volume vaccines at low cost. Crude plant extracts containing influenza hemagglutinin are considered to use as vaccine sources because of avoidance of related purification steps resulting in low cost production allowing veterinary applications. Highly immunogenic influenza hemagglutinins are urgently required to meet these pre-conditions...
September 20, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28930546/tick-host-pathogen-systems-immunobiology-an-interactive-trio
#12
Stephen K Wikel
Significant new insights are being made into tick modulation of host immune defenses and the implications of those host defense changes on tick-borne pathogen transmission and establishment of infection. Understanding tick saliva complexity increased with construction and analyses of salivary gland cDNA libraries. High throughput next generation sequencing and advances in proteomics are revealing greater complexity of saliva, nature of gene families and differential gene expression patterns not previously attainable...
January 1, 2018: Frontiers in Bioscience (Landmark Edition)
https://www.readbyqxmd.com/read/28930002/investigation-of-outbreaks-of-salmonella-enterica-serovar-typhimurium-and-its-monophasic-variants-using-whole-genome-sequencing-denmark
#13
Pernille Gymoese, Gitte Sørensen, Eva Litrup, John Elmerdal Olsen, Eva Møller Nielsen, Mia Torpdahl
Whole-genome sequencing is rapidly replacing current molecular typing methods for surveillance purposes. Our study evaluates core-genome single-nucleotide polymorphism analysis for outbreak detection and linking of sources of Salmonella enterica serovar Typhimurium and its monophasic variants during a 7-month surveillance period in Denmark. We reanalyzed and defined 8 previously characterized outbreaks from the phylogenetic relatedness of the isolates, epidemiologic data, and food traceback investigations. All outbreaks were identified, and we were able to exclude unrelated and include additional related human cases...
October 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28929472/-ivermectin-as-an-adjunct-in-the-treatment-of-refractory-epilepsy
#14
J A Diazgranados-Sanchez, J L Mejia-Fernandez, L S Chan-Guevara, M H Valencia-Artunduaga, J L Costa
INTRODUCTION: Ivermectin, a 22'23 dihydro derivative of avermectins beta-1a, is a highly effective veterinary and human anti parasitic, used to treat endoparasites of difficult control such as filariasis and onchocerciasis, with a median plasma life of at least of 16 hours. The recommended therapeutic doses range from 0.05 to 0.40 mg/kg, without undesirable effects or risk to human life. It went from being a great success in animal health to its application in humans, where it has had great impact...
October 1, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28929328/molecular-vaccine-prepared-by-fusion-of-xcl1-to-the-multi-epitope-protein-of-foot-and-mouth-disease-virus-enhances-the-specific-humoural-immune-response-in-cattle
#15
Kun Li, Huifang Bao, Guoyan Wei, Dong Li, Yingli Chen, Yuanfang Fu, Yimei Cao, Pinghua Li, Pu Sun, Xingwen Bai, Xueqin Ma, Jing Zhang, Zengjun Lu, Zaixin Liu
Targeting antigen to dendritic cells (DCs) is a promising way to manipulate the immune response and to design prophylactic molecular vaccines. In this study, the cattle XCL1, ligand of XCR1, was fused to the type O foot-and-mouth disease virus (FMDV) multi-epitope protein (XCL-OB7) to create a molecular vaccine antigen, and an (△)XCL-OB7 protein with a mutation in XCL1 was used as the control. XCL-OB7 protein specifically bound to the XCR1 receptor, as detected by flow cytometry. Cattle vaccinated with XCL-OB7 showed a significantly higher antibody response than that to the (△)XCL-OB7 control (P < 0...
September 19, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28929103/authorization-and-toxicity-of-veterinary-drugs-and-plant-protection-products-residues-of-the-active-ingredients-in-food-and-feed-and-toxicity-problems-related-to-adjuvants
#16
REVIEW
Szandra Klátyik, Péter Bohus, Béla Darvas, András Székács
Chemical substances applied in animal husbandry or veterinary medicine and in crop protection represent substantial environmental loads, and their residues occur in food and feed products. Product approval is governed differently in these two sectors in the European Union (EU), and the occurrence of veterinary drug (VD) and pesticide residues indicated by contamination notification cases in the Rapid Alert System for Food and Feed of the EU also show characteristic differences. While the initial high numbers of VD residues reported in 2002 were successfully suppressed to less than 100 cases annually by 2006 and on, the number of notification cases for pesticide residues showed a gradual increase from a low (approximately 50 cases annually) initial level until 2005 to more than 250 cases annually after 2009, with a halt occurring only in 2016...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28929101/current-trends-in-volume-replacement-therapy-and-the-use-of-synthetic-colloids-in-small-animals-an-internet-based-survey-2016
#17
Ivayla D Yozova, Judith Howard, Nadja E Sigrist, Katja-Nicole Adamik
The use of synthetic colloids (SCs), particularly hydroxyethyl starch (HES), in people has changed in recent years following new evidence raising concerns about their efficacy and safety. Although fluid therapy guidelines for small animals are often extrapolated from human medicine, little information exists on current practice in veterinary medicine. The objective of the present study was to investigate current fluid selection, use of plasma volume expanders including SCs, and recent changes in their use in small animal practice...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28929096/contaminants-in-foods-of-animal-origin-in-cameroon-a-one-health-vision-for-risk-management-from-farm-to-fork
#18
REVIEW
Guy B Pouokam, B U Saha Foudjo, Chi Samuel, Philomina Fankam Yamgai, A Kamda Silapeux, Joel Taguemkam Sando, G Fankam Atonde, Chiara Frazzoli
Foods of animal origin represent an important share in the diet of Cameroonian populations. Cameroon is known to be a food basket in the west and central Africa sub-region, and an important supplier of foods on the international markets. In the meantime, food importation is continuously increasing to meet the high demand of a more westernized segment of the population. Cereals, fish, sea products, eggs, honey, shrimps, chicken, and feed ingredients are important share in the international trade of agricultural products...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28929022/development-and-evaluation-of-rapid-novel-isothermal-amplification-assays-for-important-veterinary-pathogens-chlamydia-psittaci-and-chlamydia-pecorum
#19
Martina Jelocnik, Md Mominul Islam, Danielle Madden, Cheryl Jenkins, James Branley, Scott Carver, Adam Polkinghorne
BACKGROUND: Chlamydia psittaci and Chlamydia pecorum are important veterinary pathogens, with the former also being responsible for zoonoses, and the latter adversely affecting koala populations in Australia and livestock globally. The rapid detection of these organisms is still challenging, particularly at the point-of-care (POC). In the present study, we developed and evaluated rapid, sensitive and robust C. psittaci-specific and C. pecorum-specific Loop Mediated Isothermal Amplification (LAMP) assays for detection of these pathogens...
2017: PeerJ
https://www.readbyqxmd.com/read/28927469/genetic-diversity-of-haemonchus-contortus-isolated-from-sympatric-wild-blue-sheep-pseudois-nayaur-and-sheep-in-helan-mountains-china
#20
Dong-Dong Shen, Ji-Fei Wang, Dan-Yu Zhang, Zhi-Wei Peng, Tian-Yun Yang, Zhao-Ding Wang, Dwight D Bowman, Zhi-Jun Hou, Zhen-Sheng Liu
BACKGROUND: Haemonchus contortus is known among parasitic nematodes as one of the major veterinary pathogens of small ruminants and results in great economic losses worldwide. Human activities, such as the sympatric grazing of wild with domestic animals, may place susceptible wildlife hosts at risk of increased prevalence and infection intensity with this common small ruminant parasite. Studies on phylogenetic factors of H. contortus should assist in defining the amount of the impact of anthropogenic factors on the extent of sharing of agents such as this nematode between domestic animals and wildlife...
September 19, 2017: Parasites & Vectors
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