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https://www.readbyqxmd.com/read/29457685/tailored-microstructured-hyperpolarizing-matrices-for-optimal-magnetic-resonance-imaging
#1
Matthieu Cavaillès, Aurélien Bornet, Xavier Jaurand, Basile Vuichoud, David Baudouin, Mathieu Baudin, Laurent Veyre, Geoffrey Baudenhausen, Jean-Nicolas Dumez, Sami Jannin, Christophe Copéret, Chloé Thieuleux
Tailoring the physical features and the porous network architecture of silica-based hyperpolarizing solids containing TEMPO radicals, known as HYPSO (HYbrid Polarizing SOlids), enable unprecedented performance of dissolution Dynamic Nuclear Polarization (d-DNP). High polarization values up to P(1H) = 99 % were reached for samples impregnated with a mixture of H2O:D2O and loaded in a 6.7 T polarizer at temperatures around 1.2 K. These HYPSO materials combine the best performance of homogeneous DNP formulations with the advantages of solid polarizing matrices which provide hyperpolarized solutions free of any - potentially toxic - additives (radicals and glass-forming agents)...
February 19, 2018: Angewandte Chemie
https://www.readbyqxmd.com/read/29457390/-diagnosis-and-treatment-for-posterolateral-rotatory-instability-of-the-elbow
#2
Hui Kang, Wei Wang, Hong-Chuan Li, Jian Li
OBJECTIVE: To study the effects of surgical reconstruction of the lateral ligament complex for posterolateral rotatory instability (PLRI) of the elbow joint. METHODS: From January 2013 to January 2015, 20 patients with posterolateral rotatory instability of elbow joint were treated in our department. There were 12 males and 8 females whose age ranged from 30 to 60 years old, with an average age of 45.5 years old. Sixteen patients had injuries on the right side and 4 patients had injuries on the left side...
November 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29456899/facial-weakness-diplopia-and-fever-in-a-31-year-old-an-atypical-case-of-tuberculous-meningitis
#3
Ahmed H Qavi, Tasnim F Imran, Zachariah Hasan, Fariha Ilyas
Tuberculous meningitis (TBM) is an infection of the central nervous system (CNS) meninges that carries high morbidity and mortality. It is important to recognize, as patients may present with atypical symptoms. We describe the case of a 31-year-old man with a history of diabetes who presented with a sub-acute onset of right-sided facial weakness and right gaze difficulty with diplopia. History revealed low-grade fever, right-sided headache, fatigue and moderate weight loss for the past several weeks. The patient did not report neck stiffness, rigidity, fever, chills or cough...
December 7, 2017: Curēus
https://www.readbyqxmd.com/read/29456631/a-model-of-anterior-cruciate-ligament-injury-in-cynomolgus-monkeys-developed-via-arthroscopic-surgery
#4
Lei Zhang, Taiyuan Guan, Ji Qi, Shaoqun Zhang, Xin Zhou, Yang Liu, Shijie Fu
The anterior cruciate ligament (ACL) is an important structure that maintains the stability of knee joints. Animal models of ACL injury are helpful to explore its underlying mechanisms, and strategies for prevention, treatment and rehabilitation. Therefore, the aim of the present study was to develop an efficient model of ACL injury in cynomolgus monkeys via arthroscopic techniques. In the present study, 18 cynomolgus monkeys were randomly divided into a model group (n=6), a sham operation group (n=6) and a blank control group (n=6)...
March 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29456443/the-screening-process-of-a-patient-with-low-back-pain-and-suspected-thoracic-myelopathy-a-case-report
#5
Guillaume Christe, Toby Hall
Background: Thoracic disc herniations are rare and difficult to diagnose. Myelopathy is a potential consequence that can lead to irreversible neurological impairment if not treated appropriately. It is incumbent on all clinicians who see patients with low back pain (LBP) to be aware of such pathologies. This case describes a screening process in the detection of a rare serious spinal pathology and discusses the use of red flags and central nervous system signs and symptoms in the decision leading to immediate referral...
February 2018: Journal of Manual & Manipulative Therapy
https://www.readbyqxmd.com/read/29453618/lumbosacral-transitional-vertebrae-significance-of-local-bone-marrow-edema-at-the-transverse-processes
#6
Mika T Nevalainen, Eoghan McCarthy, William B Morrison, Adam C Zoga, Johannes B Roedl
OBJECTIVE: To evaluate the association between low back pain and bone marrow edema in lumbosacral transitional vertebra (LSTV) transverse processes, and to assess the prevalence of LSTV in a physically active population. MATERIALS AND METHODS: Individuals with LSTV on coronal MRI studies were identified in a retrospective review by keyword search from PACS. In total, 140 cases were reviewed by two fellowship-trained musculoskeletal radiologists. Data on associated low back pain were collected from patient records at the time of the imaging...
February 16, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29452329/a-frontal-sinus-osteoma-accompanied-by-an-intracranial-mucocele-and-local-hyperostosis-frontalis-interna
#7
Yang Yang, Liang Wang, Zhen Wu
Frontal sinus osteoma accompanied by intracranial mucocele and local hyperostosis frontalis interna has never been reported. A 47-year-old woman presented with a 3-month history of intermittent headache. Physical examination revealed no neurological abnormality. Contrasted MRI showed a frontal heterogeneously enhanced lesion with adjacent non-enhanced cyst. Computed tomography showed a bone-density mass, which was accompanied by local hyperostosis frontalis interna, filled the left frontal sinus and extended intracranially...
February 13, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29451811/role-of-tendoscopy-in-treating-stage-ii-posterior-tibial-tendon-dysfunction
#8
Alessio Bernasconi, Francesco Sadile, Matthew Welck, Nazim Mehdi, Julien Laborde, François Lintz
BACKGROUND: Stage II tibialis posterior tendon dysfunction (PTTD) resistant to conservative therapies is usually treated with invasive surgery. Posterior tibial tendoscopy is a novel technique being used in the assessment and treatment of posterior tibial pathology. The aims of this study were (1) to clarify the role of posterior tibial tendon tendoscopy in treating stage II PTTD, (2) to arthroscopically classify spring ligament lesions, and (3) to compare the arthroscopic assessment of spring ligament lesions with magnetic resonance imaging (MRI) and ultrasonographic (US) data...
February 1, 2018: Foot & Ankle International
https://www.readbyqxmd.com/read/29450605/abbreviated-mpmri-protocol-for-diffuse-liver-disease-a-practical-approach-for-evaluation-and-follow-up-of-nafld
#9
Guilherme Moura Cunha, Cristiane A Villela-Nogueira, Anke Bergman, Flavia Paiva Proença Lobo Lopes
AIM: Multiparametric magnetic resonance imaging (mpMRI) may help determine the metabolic profile of patients with obesity and metabolic syndrome in addition to their clinical and laboratory biomarkers for diagnosis and monitoring. An abbreviated mpMRI protocol may be a faster, less-costly, and easier to perform alternative for the diagnosis, treatment, and follow-up of patients with NAFLD and for use in clinical trials. OBJECTIVE: To evaluate an abbreviated mpMRI protocol tailored to analyze quantitative imaging features of patients with obesity and NAFLD and assess its use during treatment...
February 15, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29444466/interference-and-problem-size-effect-in-multiplication-fact-solving-individual-differences-in-brain-activations-and-arithmetic-performance
#10
Alice De Visscher, Stephan E Vogel, Gernot Reishofer, Eva Hassler, Karl Koschutnig, Bert De Smedt, Roland H Grabner
In the development of math ability, a large variability of performance in solving simple arithmetic problems is observed and has not found a compelling explanation yet. One robust effect in simple multiplication facts is the problem size effect, indicating better performance for small problems compared to large ones. Recently, behavioral studies brought to light another effect in multiplication facts, the interference effect. That is, high interfering problems (receiving more proactive interference from previously learned problems) are more difficult to retrieve than low interfering problems (in terms of physical feature overlap, namely the digits, De Visscher and Noël, 2014)...
February 11, 2018: NeuroImage
https://www.readbyqxmd.com/read/29442350/occult-phosphaturic-mesenchymal-tumor-of-femur-cortex-causing-oncogenic-osteomalacia-diagnostic-challenges-and-clinical-outcomes
#11
Deep Dutta, Raghuvansh Kumar Pandey, Rakhee Gogoi, Nagender Solanki, Renu Madan, Anupam Mondal, Shruti Dogra, Pradeep Thapa
BACKGROUND: Tumor induced osteomalacia (TIO) are extremely rare paraneoplastic syndrome with less than 300 reported cases. This report highlights the pitfalls and challenges in diagnosing and localizing TIO in patients with refractory and resistant osteomalacia. PATIENT AND METHODS: 41- year gentleman with 4-year history of musculoskeletal weakness and pathologic fractures presented in wheelchair bound incapacitated state of 1-year duration. Investigations were significant for severe hypophosphatemia, severe phosphaturia, normal serum calcium, reduced 1,25-dihydroxy vitamin-D, elevated ALP, elevated intact parathyroid hormone (iPTH), and pseudo-fractures involving pelvis and bilateral femur...
February 14, 2018: Endokrynologia Polska
https://www.readbyqxmd.com/read/29441430/prenatal-diagnosis-of-apert-syndrome-using-ultrasound-magnetic-resonance-imaging-and-three-dimensional-virtual-physical-models-three-case-series-and-literature-review
#12
Heron Werner, Pedro Castro, Pedro Daltro, Jorge Lopes, Gerson Ribeiro, Edward Araujo Júnior
OBJECTIVE: This aimed to describe the prenatal diagnosis of three cases of Apert syndrome using two-dimensional (2D) and three-dimensional (3D) ultrasound, magnetic resonance imaging (MRI), and 3D virtual/physical models. METHODS: We retrospectively analyzed three cases of Apert syndrome at our service. The prenatal diagnostic methods used were 2D ultrasound, 3D ultrasound in conventional and HDlive rendering modes, T2-weighted MRI sequences, and 3D virtual/physical models from MRI or 3D ultrasound scan data...
February 13, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29438835/structural-mri-correlates-of-cognitive-function-in-multiple-sclerosis
#13
Artemios Artemiadis, Maria Anagnostouli, Ioannis Zalonis, Konstantinos Chairopoulos, Nikos Triantafyllou
BACKGROUND: Cognitive impairment (CI) has been associated with numerous magnetic resonance imaging (MRI) indices in multiple sclerosis (MS) patients. In this study we investigated the association of a large set of 2D and 3D MRI markers with cognitive function in MS. METHODS: A sample of 61 RRMS patients (mean age 41.8 ± 10.6 years old, 44 women, mean disease duration 137.9 ± 83.9 months) along with 51 age and gender matched healthy controls was used in this cross-sectional study...
February 6, 2018: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29437060/degenerative-subtalar-joints-complicated-by-medial-plantar-intraneural-cysts-cutting-the-cystic-articular-branch-prevents-recurrence
#14
P Laumonerie, F Lapègue, N Reina, M Tibbo, M Rongières, M Faruch, P Mansat
AIMS: The pathogenesis of intraneural ganglion cysts is controversial. Recent reports in the literature described medial plantar intraneural ganglion cysts (mIGC) with articular branches to subtalar joints. The aim of the current study was to provide further support for the principles underlying the articular theory, and to explain the successes and failures of treatment of mICGs. PATIENTS AND METHODS: Between 2006 and 2017, five patients with five mICGs were retrospectively reviewed...
February 2018: Bone & Joint Journal
https://www.readbyqxmd.com/read/29436307/cancers-of-the-major-salivary-gland
#15
Eugene Son, Aru Panwar, Charles H Mosher, Daniel Lydiatt
Salivary gland malignancies are rare tumors that comprise multiple histologic entities with diverse clinical behavior. Mucoepidermoid carcinoma is the most frequent primary salivary malignancy, followed by adenoid cystic and acinic cell carcinoma. Although most salivary malignancies are asymptomatic, presentation with a rapidly enlarging mass may be accompanied by pain, functional neurologic deficits, soft-tissue invasion, or nodal enlargement. Assessment of clinical behavior and physical exam greatly contributes to diagnostic workup...
February 2018: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29432610/accelerometer-physical-activity-is-associated-with-greater-gray-matter-volumes-in-older-adults-without-dementia-or-mild-cognitive-impairment
#16
Shannon Halloway, Konstantinos Arfanakis, JoEllen Wilbur, Michael E Schoeny, Susan J Pressler
Objectives: Physical activity (PA) is a modifiable health behavior that can protect against age-related gray matter atrophy and cognitive dysfunction. Current studies of PA and gray matter failed to utilize device measures of PA and do not focus on adults >80 years. Thus, the purpose of this secondary analysis was to examine cross-sectional associations between accelerometer lifestyle PA and (a) gray matter volumes and (b) cognitive function, controlling for demographics and health status...
February 8, 2018: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/29430243/the-effect-of-motion-artifacts-on-near-infrared-spectroscopy-nirs-data-and-proposal-of-a-video-nirs-system
#17
Masayuki Satoh, Keisuke Okamoto, Ken-Ichi Tabei, Hirotaka Kida, Hidekazu Tomimoto, Hideo Eda
Aims: The aims of this study were (1) to investigate the influence of physical movement on near-infrared spectroscopy (NIRS) data, (2) to establish a video-NIRS system which simultaneously records NIRS data and the subject's movement, and (3) to measure the oxygenated hemoglobin (oxy-Hb) concentration change (Δoxy-Hb) during a word fluency (WF) task. Experiment 1: In 5 healthy volunteers, we measured the oxy-Hb and deoxygenated hemoglobin (deoxy-Hb) concentrations during 11 kinds of facial, head, and extremity movements...
September 2017: Dementia and Geriatric Cognitive Disorders Extra
https://www.readbyqxmd.com/read/29430056/osteochondral-lesion-of-the-distal-tibial-plafond-in-an-adolescent-soccer-player-a-case-report
#18
Melissa Corso, Christopher DeGraauw, William Hsu
Introduction: Osteochondral lesions of the tibial plafond account for approximately 2.6% of osteochondral lesions in the ankle. There are few cases describing this lesion in the literature, with little information on mechanism of injury, history/physical findings or recommendations for management. Case Presentation: A 17-year-old male competitive soccer player presented with a 6-7 month history of medial ankle pain after an inversion sprain. He presented with locking and giving way of the ankle with weight-bearing and pushing off the foot to the contralateral side...
December 2017: Journal of the Canadian Chiropractic Association
https://www.readbyqxmd.com/read/29430055/conservative-management-of-mri-confirmed-knee-osteoarthritis-with-instrument-assisted-soft-tissue-mobilization-joint-manipulation-and-platelet-rich-plasma
#19
Arif Karmali
Objective: To describe the successful conservative management of a patient with chronic degenerative knee pain. Clinical Features: An active 47 year-old female office-worker with intermittent right knee pain inferolateral to the right patella for eight months described difficulty ascending stairs, sitting on a chair for one hour, and squatting. A physical exam led to the diagnosis of a suspected chronic degenerative tear of the posterior horn of the right medial meniscus and chronic right subpatellar chondrosis, in addition to extensive cartilaginous degeneration revealed by an MRI study conducted prior to initial presentation...
December 2017: Journal of the Canadian Chiropractic Association
https://www.readbyqxmd.com/read/29429784/rapid-progressive-visual-decline-and-visual-field-defects-in-two-patients-with-the-heidenhain-variant-of-creutzfeld-jakob-disease
#20
Janine Lenk, Kay Engellandt, Naim Terai, Antonia Bottesi, Egbert Matthé
BACKGROUND: Heidenhain variant of Creutzfeldt-Jakob (HvCJD) is a rare disease, patients presenting with loss of visual acuity and a decline in visual fields. CASE PRESENTATION: Two patients with rapid loss of visual acuity and declining visual fields presented with homonymic hemianopsia over several weeks. Cranial MRI showed neither stroke nor other morphological changes explaining the severe visual field defects. Neurological examination revealed no pathologies...
February 8, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
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