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https://www.readbyqxmd.com/read/29679734/cortical-networks-for-encoding-near-and-far-space-in-the-non-human-primate
#1
Justine Cléry, Olivier Guipponi, Soline Odouard, Claire Wardak, Suliann Ben Hamed
While extra-personal space is often erroneously considered as a unique entity, early neuropsychological studies report a dissociation between near and far space processing both in humans and in monkeys. Here, we use functional MRI in a naturalistic 3D environment to describe the non-human primate near and far space cortical networks. We describe the co-occurrence of two extended functional networks respectively dedicated to near and far space processing. Specifically, far space processing involves occipital, temporal, parietal, posterior cingulate as well as orbitofrontal regions not activated by near space, possibly subserving the processing of the shape and identity of objects...
April 18, 2018: NeuroImage
https://www.readbyqxmd.com/read/29679354/low-serum-phosphate-is-associated-with-ischemic-stroke-in-hemodialysis-patients
#2
Tsang-Shan Chen, Chao-Hung Chen, Chien-An Chen, Li-Ping Chou, Chi-Chu Liu
BACKGROUND: Hemodialysis patients have a high incidence of ischemic stroke. However, the association between serum phosphate levels and ischemic stroke is controversial among hemodialysis patients. The present study is used to evaluate whether serum phosphate levels are associated with ischemic stroke among patients undergoing hemodialysis. METHODS: A total of 84 hemodialysis patients were followed up for 8 years. Data collection included chart reviews and assessments of laboratory records...
April 20, 2018: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/29676349/partial-corpus-callosal-agenesis-with-ventriculomegaly-and-sulcal-anomaly-in-a-10-year-old-child
#3
Austine Abebe Osawe, Saleh M Kabir, Anas Ismail
Agenesis of the corpus callosum is a heterogeneous, congenital neurodevelopmental condition that can be observed either in isolation or in combination with other brain abnormalities. Patients often present early with characteristic neurologic and physical manifestations. This case discusses a 10-year-old boy who presented to a tertiary health facility in Northern Nigeria with 6-month history of seizure disorder, cognitive impairment and urinary incontinence and had classical magnetic resonance imaging (MRI) findings consistent with partial corpus callosum agenesis in combination with other brain abnormalities...
January 2018: Nigerian Postgraduate Medical Journal
https://www.readbyqxmd.com/read/29674364/health-and-prevention-enhancement-h-peace-a-retrospective-population-based-cohort-study-conducted-at-the-seoul-national-university-hospital-gangnam-center-korea
#4
Changhyun Lee, Eun Kyung Choe, Ji Min Choi, Yunji Hwang, Young Lee, Boram Park, Su Jin Chung, Min-Sun Kwak, Jong-Eun Lee, Joo Sung Kim, Sue Kyung Park, Sang-Heon Cho
PURPOSE: The Health and Prevention Enhancement (H-PEACE) study was designed to investigate the association of diagnostic imaging results, biomarkers and the predisease stage of non-communicable diseases (NCDs), such as malignancies and metabolic diseases, in an average-risk population in Korea. PARTICIPANTS: This study enrolled a large-scale retrospective cohort at the Healthcare System Gangnam Center, Seoul National University Hospital, from October 2003 to December 2014...
April 19, 2018: BMJ Open
https://www.readbyqxmd.com/read/29673820/extra-osseous-ewing-s-sarcoma-of-sciatic-nerve-masquerading-as-benign-nerve-sheath-tumor-and-presented-as-lumbar-radiculopathy
#5
Jung Soo Bang, Nitin Adsul, Jae-Hyeon Lim, Il-Tae Jang
BACKGROUND: Extraosseous Ewing Sarcoma (EES) arising from peripheral nerves is extremely rare with only 11 cases, mentioned in the literature. It poses a diagnostic challenge to the clinicians due to its nonspecific presentation and rare occurrence. CASE DESCRIPTION: A 56-year-old woman came with a history of low back pain and intractable right leg pain. Physical examination revealed the normal motor power of both lower limbs with decreased sensation along the lateral aspect of the foot with decreased ankle reflex...
April 16, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29672768/microsurgical-resection-of-a-meningioma-at-the-entrance-of-dorello-s-canal-causing-vi-cranial-nerve-compression-2-dimensional-operative-video
#6
Abdulrahman Alturki, Alejandro Enriquez-Marulanda, Raghav Gupta, Ajith J Thomas, Christopher S Ogilvy
We describe the case of a 73-yr-old female patient with a 2-yr history of diplopia that has progressively become worse. Physical examination revealed a right VI cranial nerve (CN) palsy. Magnetic resonance imaging and angiography showed a dolichoectatic basilar artery near the VI CN. A suboccipital craniectomy was performed, initially with the intention to perform a microvascular decompression; however, a red mass was encountered at the entrance of the right Dorello's canal that was compressing the VI CN. Complete resection of the lesion was done and decompression of the nerve was accomplished...
April 17, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29672184/oral-supplementation-with-beta-hydroxy-beta-methylbutyrate-arginine-and-glutamine-improves-lean-body-mass-in-healthy-older-adults
#7
Amy C Ellis, Gary R Hunter, Amy M Goss, Barbara A Gower
Oral intake of beta-hydroxy-beta-methylbutyrate (HMB), arginine, and glutamine may ameliorate muscle loss by stimulating protein synthesis and decreasing protein degradation while simultaneously decreasing inflammation. Previous studies provide evidence for improvement in body composition with dietary supplementation of these ingredients among patients with muscle-wasting diseases. The objectives of this study were to examine the effects of this amino acid mixture on lean body mass, muscle volume, and physical function among healthy older adults...
April 19, 2018: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/29671088/magnetic-gold-nanoparticle-labeled-heparanase-monoclonal-antibody-and-its-subsequent-application-for-tumor-magnetic-resonance-imaging
#8
Ning Li, Meng-Meng Jie, Min Yang, Li Tang, Si-Yuan Chen, Xue-Mei Sun, Bo Tang, Shi-Ming Yang
Heparanase (HPA) is ubiquitously expressed in various metastatic malignant tumors; previous studies have demonstrated that HPA was a potential tumor-associated antigen (TAA) for tumor immunotherapy. We sought to evaluate the feasibility of HPA as a common TAA for magnetic resonance imaging (MRI) of tumor metastasis and its potential application in tumor molecular imaging. We prepared a targeted probe based on magnetic gold nanoparticles coupled with an anti-HPA antibody for the specific detection of HPA by MRI...
April 18, 2018: Nanoscale Research Letters
https://www.readbyqxmd.com/read/29670797/recurrent-migratory-transient-bone-marrow-edema-of-the-knees-associated-with-low-vitamin-d-and-systemic-low-bone-mineral-density-a-case-report-and-literature-review
#9
Omar Alsaed, Mohammad Hammoudeh
Transient bone marrow edema (TBME) is a self-limiting disease characterized by joint pain with localized bone marrow edema by MRI and has been reported in many case series and case reports. It is well known that joints of the lower extremity including hips, knees, ankles, and feet are the classical sites for TBME. Many theories have been proposed for the pathogenesis of TBME. Systemic osteopenia and vitamin D deficiency is one of the theories that have been suggested in the last few years. In this case report, we present a middle-aged male patient, who presented with 4 attacks of TBME in both knees between September 2016 and August 2017...
2018: Case Reports in Rheumatology
https://www.readbyqxmd.com/read/29668636/spinal-dural-arteriovenous-fistula-presenting-with-subarachnoid-hemorrhage-a-case-report
#10
Jingzhe Han, Duanhua Cao, Hongmei Wang, Ye Ji, Zhilei Kang, Jianguo Zhu
RATIONALE: Subarachnoid hemorrhage (SAH) is a common and serious disease and one of the most important differential diagnoses in the emergency department. PATIENT CONCERNS: A 39-year-old female patient with a 12 years' history of migraine, presented with a sudden headache combined with motor aphasia. Physical examination suggested probable positive neck resistance. SAH was confirmed by magnetic resonance imaging. In addition, spinal digital subtraction angiography and spinal vascular computed tomography angiography indicated spinal arteriovenous malformation (SAVM)...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29668564/a-systematic-review-of-the-utility-of-the-hoffmann-sign-for-the-diagnosis-of-degenerative-cervical-myelopathy
#11
Alexandra Fogarty, Eric Lenza, Gaurav Gupta, Peter Jarzem, Kaberi Dasgupta, Mohan Radhakrishna
STUDY DESIGN: Systematic review OBJECTIVE.: To determine the validity of the Hoffmann sign for the detection of degenerative cervical myelopathy (DCM) for patients presenting with cervical complaints. SUMMARY OF BACKGROUND DATA: While physical exam maneuvers are often used to diagnose DCM, no previous review has synthesized diagnostic accuracy data. METHODS: Medline, Embase and HealthStar were searched for articles from 1 January 1947 to 1 March 2017 using the following terms: Spinal Cord Diseases, Spinal Cord Compression, Cervical Vertebrae, Signs and Symptoms, Physical Examination, Epidemiologic studies, Epidemiologic Research Design, Predictive Value of Tests and Myelopathy...
April 17, 2018: Spine
https://www.readbyqxmd.com/read/29668367/which-patients-with-cervical-squamous-cell-carcinoma-might-benefit-from-neoadjuvant-chemotherapy
#12
Omar Mahmoud, Mark H Einstein
The Oncology Grand Rounds series is designed to place original reports published in the Journal into clinical context. A case presentation is followed by a description of diagnostic and management challenges, a review of the relevant literature, and a summary of the authors' suggested management approaches. The goal of this series is to help readers better understand how to apply the results of key studies, including those published in Journal of Clinical Oncology, to patients seen in their own clinical practice...
April 18, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29665854/a-community-based-physical-activity-intervention-to-prevent-mobility-related-disability-for-retired-older-people-retirement-in-action-react-study-protocol-for-a-randomised-controlled-trial
#13
Afroditi Stathi, Janet Withall, Colin J Greaves, Janice L Thompson, Gordon Taylor, Antonieta Medina-Lara, Colin Green, James Bilzon, Selena Gray, Heidi Johansen-Berg, Claire E Sexton, Max J Western, Jolanthe L de Koning, Jessica C Bollen, Sarah J Moorlock, Naiara Demnitz, Poppy Seager, Jack M Guralnik, W Jack Rejeski, Ken R Fox
BACKGROUND: The REtirement in ACTion (REACT) study is a multi-centre, pragmatic, two-arm, parallel-group randomised controlled trial (RCT) with an internal pilot phase. It aims to test the effectiveness and cost-effectiveness of a community, group-based physical activity intervention for reducing, or reversing, the progression of functional limitations in older people who are at high risk of mobility-related disability. METHODS/DESIGN: A sample of 768 sedentary, community-dwelling, older people aged 65 years and over with functional limitations, but who are still ambulatory (scores between 4 and 9 out of 12 in the Short Physical Performance Battery test (SPPB)) will be randomised to receive either the REACT intervention, delivered over a period of 12 months by trained facilitators, or a minimal control intervention...
April 17, 2018: Trials
https://www.readbyqxmd.com/read/29664106/effect-of-therapeutic-exercise-on-knee-osteoarthritis-after-intra-articular-injection-of-botulinum-toxin-type-a-hyaluronate-or-saline-a-randomized-controlled-trial
#14
Xiao Bao, Jie-Wen Tan, Michael Flyzik, Xian-Cong Ma, Howe Liu, Hui-Yu Liu
OBJECTIVE: To study the effect of therapeutic exercise on knee osteoarthritis after injection of botulinum toxin type A, hyaluronate or saline. METHODS: Sixty participants with knee osteoarthritis were randomly assigned to 3 groups: injection of saline (control) (group A), botulinum toxin type A (group B), or hyaluronate (group C). All participants received therapeutic exercise. Western Ontario and McMaster Universities Osteoarthritis Index questionnaire score, visual analogue scale pain scale, and Medical Outcomes Study 36-item Health Survey were conducted at baseline, and at the end of the 4th and 8th weeks...
April 17, 2018: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29662741/predictive-factors-for-the-outcome-of-surgical-treatment-of-lumbar-spondylolysis-in-young-sporting-individuals
#15
Ujjwal K Debnath, B E Scammell, Brian J C Freeman, Jeffrey R McConnell
Study Design: Retrospective consecutive case series. Objectives: Only few sporting individuals with symptomatic lumbar pars injuries require surgical repair and it is often difficult to predict the outcome following surgery. The factors that predict the outcome after direct repair of lumbar pars defect was evaluated clinically and statistically. The preoperative background variables both subjective and objective as well as radiological evaluation were used in a multiple regression model to find the strong predictors of postoperative outcome as measured by VAS (visual analogue scores), ODI (Oswestry Disability Index) and SF-36 (Short Form)...
April 2018: Global Spine Journal
https://www.readbyqxmd.com/read/29661070/scaphoid-cysts-literature-review-of-etiology-treatment-and-prognosis
#16
Tyler Safran, Jessica Hazan, Becher Al-Halabi, Hassan Al-Naeem, Sabrina Cugno
BACKGROUND: Cystic lesions of the carpal bones are rare entities that are infrequently reported in the literature. Scaphoid intraosseous cystic lesions represent a rare subset of carpal bone cysts. This review aims to summarize the available evidence on the evaluation and treatment of scaphoid cystic lesions to help guide clinical management. METHODS: Systematic electronic searches were performed using PubMed, Ovid, and Embase databases. Studies included were graded for their risk of bias...
April 1, 2018: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/29658089/electrophysiological-properties-of-rat-vestibular-labyrinth-and-their-effect-on-parameters-of-transmitted-voltage-pulses
#17
V P Demkin, V V Udut, P P Shchetinin, M V Svetlik, S V Mel'nichuk, A P Shchetinina, M O Pleshkov, D N Starkov, O V Demkin, H Kingma
We propose a new approach to optimization of electrical stimulation of the vestibular nerve and improving the transfer function of vestibular implant. A mathematical model of the vestibular organ is developed based on its anatomy, the model premises, 3D-analysis of MRI and CT images, and mathematical description of physical processes underlying propagation of alternating electric current across the tissues of vestibular labyrinth. This approach was tested in vitro on the rat vestibular apparatus and had been examined anatomically prior to the development of its mathematical model and equivalent electrical circuit...
April 16, 2018: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/29656321/multi-center-reproducibility-of-structural-diffusion-tensor-and-resting-state-functional-magnetic-resonance-imaging-measures
#18
S Deprez, Michiel B de Ruiter, S Bogaert, R Peeters, J Belderbos, D De Ruysscher, S Schagen, S Sunaert, P Pullens, E Achten
PURPOSE: The aim of this study is to assess multi-center reproducibility and longitudinal consistency of MRI imaging measurements, as part of a phase III longitudinal multi-center study comparing the neurotoxic effect following prophylactic cranial irradiation with hippocampal avoidance (HA-PCI), in comparison with conventional PCI in patients with small-cell lung cancer. METHODS: Harmonized MRI acquisition protocols from six participating sites and two different vendors were compared using both physical and human phantoms...
April 14, 2018: Neuroradiology
https://www.readbyqxmd.com/read/29656266/cortical-and-subcortical-changes-in-patients-with-premenstrual-syndrome
#19
Peng Liu, Ying Wei, Yingying Fan, Hai Liao, Geliang Wang, Ru Li, Gaoxiong Duan, Demao Deng, Wei Qin
BACKGROUND: Premenstrual syndrome (PMS) is characterized by a series of emotional, physical and behavioral symptoms. Although PMS is related to dysfunctions of the central nervous system, the neuropathological mechanism of PMS still has not been clearly established. The aim of this study is to evaluate potential differences in both cortical thickness and subcortical volumes in PMS patients compared to healthy controls (HCs). METHODS: Twenty PMS patients and twenty HCs underwent a structural magnetic resonance imaging scan and clinical assessment...
April 7, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29656234/intramasseteric-schwanoma-mimicking-an-isolated-cheek-mass-case-report-and-review-of-literature
#20
Nazir El Khatib, Antoine Nehme, Selim Nasser, Nabil Moukarzel, Houssam Khodor Abtar
INTRODUCTION: Schwannoma is a benign well circumscribed tumor of the nerve sheath and it is mostly localized in the head and neck. Intramasseteric schwannoma represents a very rare entity and a few cases have been described in the literature. PRESENTATION OF CASE: We present a case of an isolated, asymptomatic and slowly progressive right cheek tumor in a middle aged man. Although multiple investigations, including neck scanner and fine needle aspiration, were done, the diagnosis was obscure and difficult before definite surgical resection...
April 7, 2018: International Journal of Surgery Case Reports
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